scholarly journals EFFEKTIFITAS OBAT HERBAL TERHADAP PENYEMBUHAN JERAWAT : A Systematic Review

2021 ◽  
Vol 1 (2) ◽  
pp. 152-162
Author(s):  
Al Ihksan Agus
Keyword(s):  
Side Effects ◽  
Skin Diseases ◽  
Aloe Vera ◽  
Punica Granatum ◽  
Herbal Remedies ◽  
Tea Tree ◽  
Common Skin ◽  
Herbal Plants ◽  
Aloe Ferox ◽  
Anti Inflammatory

Acne is one of the most common skin diseases and usually affects almost everyone. Herbal remedies can be given to treat acne and do not cause side effects. The purpose of writing is to see the effectiveness of herbal remedies for healing acne. Methods: Recent literature reviews were conducted using the electronic databases of Pubmed, Wiley Online and Science Direct. The review method uses keyword terms and phrases of Herbal Medicine, Acne, and Facial Treatment. Results: From the results of 9 studies, it was found that there was anti-acne activity of herbal plants and was relatively safe because there were no severe side effects compared to conventional or synthetic treatments. And there is the effectiveness of herbal remedies for healing acne. Conclusion: Herbal plants have antioxidant, anti-inflammatory, antibacterial and anti-inflammatory effects. Some of the recommended plants based on journal reviews for treating acne include: Nigela Sativa L, Amurense Phellodendron, Tea Tree Oil, Mangosteen Fruit Skin, Aloe Vera, Lavandulla, Paper Murbey, Green Tea, Hops, Aloe Ferox, Punica Granatum (Pomegranate).

scholarly journals ODREĐIVANJE HEMIJSKOG SASTAVA RAZLIČITIH EKSTRAKATA ČUVARKUĆE

2021 ◽  
Author(s):  
Jelena Mladenovic ◽  
◽  
Nebojsa Markovic ◽  
Ljiljana Boskovic-Rakocevic ◽  
Milena Đuric ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Vitamin C ◽  
Moisture Content ◽  
Organic Acids ◽  
Skin Diseases ◽  
Aloe Vera ◽  
First Aid ◽  
Wide Range ◽  
Anti Inflammatory

Sempervivum tectorum has a similar effect as aloe vera, which is known in the treatment of various skin diseases. This herb is considered one of the safest remedies for a wide range of skin diseases. Due to its anti-inflammatory and antiseptic properties, it also serves as an excellent first aid for burns, stings and bites, because it provides quick relief and calming. Freshly squeezed juice from the leaves of the houseplant is used in the treatment of nervous disorders, epilepsy and restless dreams. The leaves are edible and can be used as an addition to salads or stews. They are not particularly tasty, but as they are rich in water, they can be put in a juicer together with other fruits or vegetables and become a refreshing drink. It is used in folk herbal medicine and as a medicine. The aim of this study was to determine the moisture content, total extracted substances, extract density, vitamin C, organic acids and proteins in house extracts.

Comparison of the efficacy of tea tree (Melaleuca alternifolia) oil with other current pharmacological management in human demodicosis: A Systematic Review

Parasitology ◽  
2020 ◽  
Vol 147 (14) ◽  
pp. 1587-1613
Author(s):  
Nelson Siu Kei Lam ◽  
Xin Xin Long ◽  
Xuegang Li ◽  
Li Yang ◽  
Robert C Griffin ◽  
...  
Keyword(s):  
Side Effects ◽  
Cost Effective ◽  
Research Needs ◽  
Tea Tree Oil ◽  
Melaleuca Alternifolia ◽  
Pharmacological Management ◽  
Tea Tree ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Delivery Technology

AbstractVarious treatments are found to be moderately effective in managing Demodex-related diseases except tea tree oil (TTO) and terpinen-4-ol (T4O), which showed superior miticidal and anti-inflammatory effects in numerous clinical studies. Their possible effects include lowering mite counts, relieving Demodex-related symptoms, and modulating the immune system. This review summarizes the current clinical topical and oral treatments in human demodicosis, their possible mechanisms of action, side-effects and resistance in treating this condition. TTO (especially T4O) is found to be the most effective followed by metronidazole, ivermectin and permethrin in managing the disease. This is because TTO has anti-parasitic, anti-bacterial, anti-fungal, anti-inflammatory and wound-healing effects. Furthermore, nanoTTO can even release its contents into fungus and Pseudomonas biofilms. Combinations of different treatments are occasionally needed for refractory cases, especially for individuals with underlying genetic predisposal or are immuno-compromised. Although the current treatments show efficacy in controlling the Demodex mite population and the related symptoms, further research needs to be focused on the efficacy and drug delivery technology in order to develop alternative treatments with better side-effects profiles, less toxicity, lower risk of resistance and are more cost-effective.

scholarly journals Release of Aloe vera Extracts from Therapeutic Lenses

2020 ◽  
Vol 10 (24) ◽  
pp. 9055
Author(s):  
Alessandra Pulliero ◽  
Aldo Profumo ◽  
Alberto Izzotti ◽  
Sergio Claudio Saccà
Keyword(s):  
Drug Therapy ◽  
Side Effects ◽  
Aloe Vera ◽  
Corneal Surface ◽  
Ocular Surgery ◽  
Adverse Side Effects ◽  
Ocular Irritation ◽  
Anti Inflammatory ◽  
Microbial Agent

Aloe vera extracts have been used for drug therapy due to their antimicrobial, anti-inflammatory, and epithelia-regenerative actions. Considering the possible adverse side effects on the corneal surface of anti-microbial agent administration after ocular surgery, it is of interest to identify the ability of Aloe vera extract release from a therapeutic lens to prevent ocular irritation. The aim of this research was to evaluate the effects of different lens types on the availability and efficacy of releasing Aloe vera extracts in which they are soaked. Two lens types were examined: (1) non-ionic hydrogel lenses and (2) ionic hydrogel lenses. Aloe vera availability was quantified by LC–MS, and activity was quantified by a spectrophotometer (Nanodrop) at different times: (a) 30 min, (b) 60 min, (c) 2 h, (d) 6 h, and (e) 24 h. The lens allowing for the most abundant passage of Aloe vera extracts was the ionic hydrogel lens, followed by the non-ionic hydrogel lens. The obtained results demonstrate that the best lens allowing for the high and stable release of Aloe vera extract to the corneal surface are those composed of ionic hydrogels.

scholarly journals Development of Poly Herbal Cream Formulations Containing Wild Growing Omani Medicinal Plants

2021 ◽  
pp. 57-65
Author(s):  
Mullaicharam Bhupathyraaj ◽  
Lakshmi Sreenath ◽  
Hanan Obaid Al-Habsi ◽  
Nirmala Halligudi
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Sebaceous Gland ◽  
Contact Allergy ◽  
Research Work ◽  
Aloe Vera ◽  
Herbal Medication ◽  
Herbal Plants ◽  
Limiting Condition ◽  
Bacterial Effect

Acne is derived from the Greek word “acme” which means “prime of life”. It is mostly considered to be benign and self-limiting condition but if it is ignored than it can progress to lifetime presence and scaring of the skin. Almost 85% of adolescence are affected by acne and from here males are at higher ration that female due to testosterone level that causes increase size in sebaceous gland which in turn causes more production of sebum (oil production). Women are affected more during adulthood due to imbalance of premenstrual hormones and over use of oil based cosmetics. There are many different factors that contribute to acne formation and it has many different forms. Herbal medication are considered safer than allopathic medicines because allopathic medicines are associated with various side effects such as like contact allergy, local irritation, scaling, photosensitivity, itching, redness, skin peeling, necrosis of the skin etc. In this study there are 3 herbal plants were used to prepare cream formulation that were used to investigate the anti-acne property. The aim of this research work was to develop formulations and to perform its evaluation as an herbal anti-acne cream. The objective of this study was to focus on the ant-acne or anti-bacterial effect of the formulated polyherbal cream containing three plants, Thyme, Aloe Vera and Basil. The results showed that the formulation 10 showed potential anti-acne property had that twice more concentration of aloe Vera than basil and thyme.

scholarly journals Topical therapy of dermatoses in children with complex localizations

2021 ◽  
pp. 192-202
Author(s):  
J. S. Kovaleva ◽  
M. V. Orobei ◽  
N. K. Zyablitskaya ◽  
N. K. Bishevskaya
Keyword(s):  
Side Effects ◽  
Skin Diseases ◽  
Topical Therapy ◽  
Age Groups ◽  
Rapid Onset ◽  
Transepidermal Water Loss ◽  
Omega 3 ◽  
Onset Of Action ◽  
Methylprednisolone Aceponate ◽  
Anti Inflammatory

The skin of children has its own anatomical and physiological characteristics, the epidermis is much thinner than in adults, the layers of the dermis and basement membrane are poorly developed and differentiated, the rate of transepidermal water loss is increased and the level of natural moisturizing factor (NMF) is reduced. Such a structure of the skin predisposes to a violation of its barrier function, contributes to the occurrence of skin diseases, provides an increased resorptive capacity of the skin and requires special attention when prescribing external therapy. The use of high-quality emollients is an important part of the basic treatment of chronic dermatoses and has its own characteristics in childhood. The use of emollients prevents the development of exacerbations and reduces the need for anti-inflammatory topical drugs. With the localization of the inflammatory process on the face, neck, genitals and large folds, it is necessary to give preference to short courses of topical glucocorticosteroids (THCS) with sufficient anti-inflammatory activity, rapid onset of action, minimal side effects. Given the high risk of side effects in children in these areas of the skin, strong fluorinated THCS, high-potency THCS, and the use of THCS under occlusive dressings are not recommended. The Russian experience of using 0.1% methylprednisolone aceponate in children of various age groups in the treatment of allergic dermatoses, including those with localization in sensitive areas, has shown good efficacy, tolerance and the absence of side effects. he article presents own clinical observations of the effectiveness of the use of combination therapy: an emollient agent - a special cream with physiological lipids omega 3-6-9 and cream methylprednisolone aceponate (with ceramides in the base) in the treatment of skin diseases in children with an emphasis on complex localizations, such as face, folds, genital area.

scholarly journals Intracellular Replication Inhibitory Effects of Tea Tree Oil on Vesicular Stomatitis Virus and Anti-inflammatory Activities in Vero Cells

2021 ◽  
Vol 8 ◽  
Author(s):  
Qi Shao ◽  
Junjie Huang ◽  
Jingui Li
Keyword(s):  
Viral Infection ◽  
Vesicular Stomatitis Virus ◽  
Skin Diseases ◽  
Quantitative Polymerase Chain Reaction ◽  
Vero Cells ◽  
Tea Tree Oil ◽  
Tea Tree ◽  
Vesicular Stomatitis ◽  
Anti Inflammatory ◽  
In Cells

Viral disease management has been proven difficult, and there are no broadly licensed vaccines or therapeutics. Vesicular stomatitis virus (VSV) is an active pathogen of wild ungulates and livestock; its infection frequently caused irreversible vesicles on the tongue or other positions, leading to enormous economic loss. Tea tree oil (TTO) has been shown to be a popular remedy for many skin diseases owing to its antibacterial, antipruritic, and anti-inflammatory effects. However, the potential effect of TTO on VSV proliferation and the corresponding inflammatory response in cells remain unclear. In this study, methyl thiazolyl tetrazolium assay was used to evaluate the cell viability of TTO, and cytotoxic concentration 50 (CC50) was calculated. Then, fluorescence observation, reverse transcription–quantitative polymerase chain reaction, Western blot (WB), and flow cytometry (FCM) assay were used to evaluate the antiviral effect of TTO against VSV under three manners of pre-infection before medication, co-administration, pretreatment before infection at safe doses to Vero cells. Meanwhile, the mRNA expressions of interleukin 8, tumor necrosis factor α, and ISG56 in cells were also detected. The results showed that the maximum safe concentration of TTO to Vero cells was 0.063% and the CC50 is 0.32%. Most notably, TTO dose-dependently inhibited the VSV GFP fluorescence generation and restrained the replication of VSV in gene and protein levels regardless of the treatment modes. Based on the results of the FCM, effective concentration 50 of TTO against VSV is 0.019%. Similarly, the mRNA expression of the above cytokines induced by viral infection was also remarkably curbed. These findings suggest that TTO emerged blocking, prophylaxis, and treatment action against VSV replication and suppressed the related inflammation in Vero cells. This study provides a novel potential for TTO fighting against viral infection and anti-inflammatory activities in Vero cells.

scholarly journals Concise review: Herbal remedies and herbal plants for constipation in children

2018 ◽  
Vol 5 (5) ◽  
pp. 2260-2267
Author(s):  
Marjan Vakili ◽  
Shokoufeh Ahmadipour ◽  
Parisa Rahmani
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Ricinus Communis ◽  
Scientific Information ◽  
Aloe Vera ◽  
Prunus Armeniaca ◽  
New Drugs ◽  
Herbal Remedies ◽  
Foeniculum Vulgare ◽  
Herbal Plants

Background: Constipation refers to difficult or delayed bowel emptying lasting 2 weeks or more and causing anxiety and distress in patients, and it is one of the most common problems in children. To treat constipation, therapeutic measures such as nutritional methods, feedback training, osmotic laxatives and stimulants, as well as stool volume enhancers, are used; however, each has its own problems and side effects. Medicinal plants have been shown to be effective in the treatment of many diseases, including constipation. Therefore, this review was conducted to report the medicinal plants effective for constipation. Methods: In the current review, eligible articles indexed from databases such as ISI (Web of Science), PubMed, Scopus, Islamic World Science Citation Center, Scientific Information Database, and Magiran were retrieved using the keywords ‘constipation’, ‘children constipation’, ‘baby’s and newborn constipation’, ‘medicinal plants’, and ‘traditional medicine’. Results: Available evidence showed that the medicinal plants Olea europaea, Phaseolus vulgaris, Prunus armeniaca, Brassica oleracea var. italica, Malus domestica, Linum usitatissimum, Aloe vera, Vitis vinifera, Foeniculum vulgare, Ficus carica, Ricinus communis, Sesamum indicum, and Descurainia sophia are some of the most important medicinal plants for the treatment of constipation in traditional medicine. Conclusion: Herbal plants are important for isolation/ preparation of new drugs in the treatment of constipation in children. In future studies, it may be beneficial to further understand and classify herbal plants/remedies, based on their mechanisms, as laxatives in the treatment of constipation.

Rola olejków eterycznych w terapii grzybicy skóry i jej przydatków

2020 ◽  
Vol 31 (4) ◽  
Author(s):  
Małgorzata Glenc-Ambroży ◽  
Laura Piejko
Keyword(s):  
Side Effects ◽  
Essential Oils ◽  
Antifungal Therapy ◽  
Skin Diseases ◽  
Tea Tree ◽  
Long Time ◽  
Chronic Skin ◽  
The Right ◽  
Synthetic Derivatives

Skin diseases are not only a health problem, but also a significant psychological and social trouble affecting every age group of patients. One of the largest groups of skin diseases are mycoses including mycoses of the skin and its appendages. The most common symptoms of infection are skin itching and burning, followed by disruption at the stratum corneum. Treatment includes the use of natural antibiotics such as griseofulvin and synthetic derivatives such as terbinafine. Chronic skin disease, which includes mycosis, necessitates taking medications for a long time, which translates into reduced effectiveness of the drug and side effects. The latest results of study herbal substances prove that they exhibit high fungistatic and fungicidal activity. Therefore, medicinal plants and their secondary metabolites are increasingly used in antifungal therapy. Essential oils are one of the products of secondary metabolism of plants. With the right dosage, they can be used for a long time with eliminating the risk of side effects. So far have been no reports of the increasing resistance of bacterial or fungal strains to the components of essential oils, which often occur in the case of long-term antibiotic therapy. The paper describes essential oils of tea tree, thyme, oregano, basil, sage, savory, clove and cinnamon, showing the greatest effectiveness in the antifungal therapy of the skin and its appendages.

scholarly journals ANTI-INFLAMMATORY PERSPECTIVES OF DIVERSE NATURAL RESOURCES

2021 ◽  
Vol 10 (4) ◽  
pp. 3270-3279
Author(s):  
Ashima Gakhar
Keyword(s):  
Natural Products ◽  
Side Effects ◽  
Chemical Diversity ◽  
New Drugs ◽  
Heart Attacks ◽  
Inflammatory Models ◽  
Conventional Drug ◽  
Increased Risk ◽  
Herbal Plants ◽  
Anti Inflammatory

irritants. It is characterized by redness, swollen joints, joint pain, stiffness, and loss of joint function. Inflammation is currently treated by NSAIDs. Unfortunately, these drugs cause an increased risk of blood clots resulting in heart attacks and strokes. Therefore, the developments of potent anti-inflammatory drugs from natural products are now under consideration. Natural products are a rich source for the discovery of new drugs because of their chemical diversity. A natural product from medicinal plants plays a major role to cure many diseases associated with inflammation. The conventional drug available in the market to treat inflammation produces various side effects. Due to these side effects, there is a need for the search for newer drugs with fewer or no side effects. There are hundreds of phytoconstituents reported to have many pharmacological activities although most of these reports are of academic interest and very few find an entry in clinical trials. The present review is directed towards the compilation of data on promising phytochemicals from herbal plants that have been tested in inflammatory models using modern scientific systems

Sign in / Sign up

Export Citation Format

Share Document