scholarly journals In vitro cytotoxic activity of Cymbopogon citratus L. and Cymbopogon nardus L. essential oils from Togo

2008 ◽  
Vol 4 (1) ◽  
Author(s):  
Koffi Koba ◽  
Komla Sanda ◽  
Catherine Guyon ◽  
Christine Raynaud ◽  
Jean-Pierre Chaumont ◽  
...  
Keyword(s):  
Essential Oils ◽  
Cytotoxic Activity ◽  
Cymbopogon Citratus ◽  
Cymbopogon Nardus

scholarly journals In VitroCytotoxic Potential of Essential Oils ofEucalyptus benthamiiand Its Related Terpenes on Tumor Cell Lines

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Patrícia Mathias Döll-Boscardin ◽  
Adilson Sartoratto ◽  
Beatriz Helena Lameiro de Noronha Sales Maia ◽  
Josiane Padilha de Paula ◽  
Tomoe Nakashima ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Essential Oils ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cytotoxic Effect ◽  
Herbal Remedy ◽  
Jurkat Cells ◽  
Tumor Cell Lines ◽  
Hela Cell Lines

EucalyptusL. is traditionally used for many medicinal purposes. In particular, someEucalyptusspecies have currently shown cytotoxic properties. Local Brazilian communities have used leaves ofE. benthamiias a herbal remedy for various diseases, including cancer. Considering the lack of available data for supporting this cytotoxic effect, the goal of this paper was to study thein vitrocytotoxic potential of the essential oils from young and adult leaves ofE. benthamiiand some related terpenes (α-pinene, terpinen-4-ol, andγ-terpinene) on Jurkat, J774A.1 and HeLa cells lines. Regarding the cytotoxic activity based on MTT assay, the essential oils showed improved results thanα-pinene andγ-terpinene, particularly for Jurkat and HeLa cell lines. Terpinen-4-ol revealed a cytotoxic effect against Jurkat cells similar to that observed for volatile oils. The results of LDH activity indicated that cytotoxic activity of samples against Jurkat cells probably involved cell death by apoptosis. The decrease of cell DNA content was demonstrated due to inhibition of Jurkat cells proliferation by samples as a result of cytotoxicity. In general, the essential oils from young and adult leaves ofE. benthamiipresented cytotoxicity against the investigated tumor cell lines which confirms their antitumor potential.

scholarly journals EFFICACY OF FOUR ESSENTIAL OILS ON FUSARIUM HEAD BLIGHT CAUSED BY FUSARIUM OXYSPORUM F. SP. RADICIS LYCOPERSICI (FORL), A FUNGAL TELLURIC PATHOGEN OF TOMATO GROWN UNDER COVER

2021 ◽  
Vol 9 (11) ◽  
pp. 1018-1030
Author(s):  
Doumbouya Mohamed ◽  
◽  
Kouame Koffi Gaston ◽  
Brou Kouassi Guy ◽  
NGuessan Aya Carine ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Fusarium Oxysporum ◽  
Fusarium Head Blight ◽  
Growth Parameters ◽  
Curative Treatment ◽  
Life Stages ◽  
Cymbopogon Citratus ◽  
Head Blight

Fusarium head blight caused by Fusarium oxysporum f. sp. Radicis-lycopersici (FORL) is a constraint to tomato cultivation in Korhogo, Côte dIvoire. To control this disease, the antifungal activity of essential oils extracted from certain plants was evaluated in comparison with that of a synthetic fungicide for use. In vitro tests were performed on the different life stages of FORL. The in vivo evaluations consisted in carrying out two modes of treatment (curative and preventive) on plants of a susceptible variety of tomato inoculated with FORL. The results showed that the essential oils significantly reduced the different life stages of F.oxysporum f. sp. Radicis-lycopersici (FORL) as did the synthetic product. Thus, the essential oil Cymbopogon citratus at concentrations of 4000 and 6000 ppm strongly inhibited in vitro the different stages of FORL. In preventive and curative treatment, the essential oils not only improved the growth parameters of tomato plants but also reduced the incidence and severity of diseases. Thus, it was found that Cymbopogon citratus (4000 ppm) in preventive treatment, and Banko plus (250 ppm) in curative treatment reduced the mortality rate of FORL up to 6.66% and improved the growth parameters and reduced the flowering time of the tomato plant.The essential oil of C. citratus could be used for biological control of F. oxysporum f. sp. Radicis lycopersici.

scholarly journals Chemical Composition and In vitro Cytotoxic Activity of the Essential Oils of Stachys rupestris and Salvia heldreichiana, Two Endemic Plants of Turkey

2013 ◽  
Vol 8 (11) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Elif Ayşe Erdogan ◽  
Ayşe Everest ◽  
Laura De Martino ◽  
Emilia Mancini ◽  
Michela Festa ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Endemic Plants ◽  
Total Oil

The chemical composition of the essential oils of two endemic plants of Turkey, Stachys rupestris Montbret et Aucher ex Benth. and Salvia heldreichiana Boiss. ex Benth., were obtained by hydrodistillation and studied by GC and GC–MS. In all, 46 compounds were identified, 22 for S. rupestris accounting for 94.6 % of the total oil and 30 for S. heldreichiana, accounting for 91.9 % of the total oil. The presence of diterpenoids (50.7%) characterized the oil from S. rupestris, while S. heldreichiana oil was rich in oxygenated sesquiterpenes (78.9%). The essential oils were evaluated for their in vitro potential cytotoxic activity on three human cancer cell lines. The oil of S. rupestris showed the higher antiproliferative activity against PC-3 and MCF-7 cancer cell lines.

scholarly journals Chemical Composition of Nardostachys grandiflora Rhizome Oil from Nepal – A Contribution to the Chemotaxonomy and Bioactivity of Nardostachys

2015 ◽  
Vol 10 (6) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Prabodh Satyal ◽  
Bhuwan K. Chhetri ◽  
Noura S. Dosoky ◽  
Ambika Poudel ◽  
William N. Setzer
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Cytotoxic Activity ◽  
Biological Activities ◽  
Mcf 7

The essential oil from the dried rhizome of Nardostachys grandiflora, collected from Jaljale, Nepal, was obtained in 1.4% yield, and a total of 72 compounds were identified constituting 93.8% of the essential oil. The rhizome essential oil of N. grandiflora was mostly composed of calarene (9.4%), valerena-4,7(11)-diene (7.1%), nardol A (6.0%), 1(10)-aristolen-9-ol (11.6%), jatamansone (7.9%), valeranal (5.6%), and cis-valerinic acid (5.7%). The chemical composition of N. grandiflora rhizome oil from Nepal is qualitatively very different than those from Indian, Chinese, and Pakistani Nardostachys essential oils. In this study we have evaluated the chemical composition and biological activities of N. grandiflora from Nepal. Additionally, 1(10)-aristolen-9-ol was isolated and the structure determined by NMR, and represents the first report of this compound from N. grandiflora. N. grandiflora rhizome oil showed in-vitro antimicrobial activity against Bacillus cereus, Escherichia coli, and Candida albicans (MIC = 156 μg/mL), as well as in-vitro cytotoxic activity on MCF-7 cells.

scholarly journals Evaluation of In Vitro Activity of Essential Oils againstTrypanosoma brucei bruceiandTrypanosoma evansi

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Nathan Habila ◽  
Abel S. Agbaji ◽  
Zakari Ladan ◽  
Isaac A. Bello ◽  
Emmanuel Haruna ◽  
...  
Keyword(s):  
Essential Oils ◽  
Eucalyptus Camaldulensis ◽  
Trypanosoma Evansi ◽  
In Vitro Activity ◽  
Eucalyptus Citriodora ◽  
Cymbopogon Citratus ◽  
Trypanosoma Brucei Brucei ◽  
Short Period ◽  
Dose Dependent

Essential oils (EOs) fromCymbopogon citratus(CC),Eucalyptus citriodora(EC),Eucalyptus camaldulensis(ED), andCitrus sinensis(CS) were obtained by hydrodistillation process. The EOs were evaluated in vitro for activity againstTrypanosoma brucei brucei(Tbb) andTrypanosoma evansi(T. evansi). The EOs were found to possess antitrypanosomal activity in vitro in a dose-dependent pattern in a short period of time. The drop in number of parasite over time was achieved doses of 0.4 g/ml, 0.2 g/mL, and 0.1 g/mL for all the EOs. The concentration of 0.4 g/mL CC was more potent at 3 minutes and 2 minutes for Tbb andT. evansi, respectively. The GC-MS analysis of the EOs revealed presence of Cyclobutane (96.09%) in CS, 6-octenal (77.11%) in EC, Eucalyptol (75%) in ED, and Citral (38.32%) in CC among several other organic compounds. The results are discussed in relation to trypanosome chemotherapy.

scholarly journals Assessment of Cytotoxic Activity of Rosemary (Rosmarinus officinalisL.), Turmeric (Curcuma longaL.), and Ginger (Zingiber officinaleR.) Essential Oils in Cervical Cancer Cells (HeLa)

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
P. A. S. R. Santos ◽  
G. B. Avanço ◽  
S. B. Nerilo ◽  
R. I. A. Marcelino ◽  
V. Janeiro ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cell Death ◽  
Essential Oils ◽  
Cytotoxic Activity ◽  
Cancer Cells ◽  
Hela Cells ◽  
Membrane Integrity ◽  
Annexin V ◽  
Cervical Cancer Cells

The objective of this study was to evaluate the cytotoxic activity of rosemary (REO,Rosmarinus officinalisL.), turmeric (CEO,Curcuma longaL.), and ginger (GEO,Zingiber officinaleR.) essential oils in HeLa cells. Cytotoxicity tests were performedin vitro, using tetrazolium (MTT) and neutral red assays for evaluation of antiproliferative activity by different mechanisms, trypan blue assay to assess cell viability and evaluation of cell morphology for Giemsa to observe the cell damage, and Annexin V to evaluate cell death by apoptosis. CEO and GEO exhibited potent cytotoxic activity against HeLa cells. IC50obtained was 36.6 μg/mL for CEO and 129.9 μg/mL for GEO. The morphology of HeLa cells showed condensation of chromatin, loss of cell membrane integrity with protrusions (blebs), and cell content leakage for cells treated with CEO and GEO, from the lowest concentrations studied, 32.81 μg/mL of CEO and 32.12 μg/mL of GEO. The Annexin V assay revealed a profile of cell death by apoptosis for both CEO and GEO. The results indicate cytotoxic activityin vitrofor CEO and GEO, suggesting potential use as anticancer agents for cervical cancer cells.

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