scholarly journals Laboratory parameters of COVID-19 patients in Khulna, Bangladesh

2021 ◽  
Vol 53 (1-2) ◽  
pp. 13-16
Author(s):  
Sabikun Nahar Chowdhury ◽  
Md Nazrul Islam ◽  
Md Mahabubur Roshed ◽  
Md Mokter Hossain ◽  
Gazi Salahuddin
Keyword(s):  
Laboratory Tests ◽  
Complete Blood Count ◽  
Mean Value ◽  
High Resolution Computed Tomography ◽  
Acute Phase Reactants ◽  
Laboratory Findings ◽  
Neutrophil Lymphocyte Ratio ◽  
Current State ◽  
Number Of Patients ◽  
Radiological Changes

Background: Recent studies have demonstrated the role of several laboratory tests in addition to RT-PCR in the diagnosis of COVID 19. Some of these, laboratory tests are indicators of the current state of the disease, while others have proved to be useful prognostic markers. Objective: The objective of our study was to evaluate the hematological, biochemical and radiological changes in COVID-19 patients. Methods: It was an observational and analytical study done retrospectively. The whole number of patients were included on the basis of inclusion and exclusion creteria. All were confirmed cases of COVID-19 patients either admitted in different hospitals or were in home isolation. Results: Total study cases was 112. Complete blood count revealed, leukocytosis was present in 9 (8.0%) cases and leucopenia in 8 (7.14%) cases. Neutrophilia was present in 27 (24.1%) cases; neutropenia in 9(8.0%) cases, lymphocylosis in 17 (15.2%) cases; lymphopenia in 28 (25%) cases. Neutrophil Lymphocyte ratio (NLR) revealed mean value of NLR 2.3(±1.1) with a range of 0.6-4.0. Decreased total circulating eosinophil count (<40/cmm) was found in 6 (5.3%) cases. Thrombocytopenia was found in 31 (27.7%) cases, Elevated ESR was found in 53 (47.3%) cases; CRP value was increased in 47 (42.0%) cases. Increased serum ferritin was found in 29 (25.9%) cases. D-dimer was increased in 35 (31.3%) cases; Xray chest showed bilateral pneumonia in 26 (23.2%) cases. High resolution computed tomography (HRCT) of chest revealed ground glass opacities in 11(9.8%) cases. Conclusion: Multiple changes in laboratory findings were observed such as altered NLR, elevated acute phase reactants, increased seromarkers (S ferritin, D-dimers) and also opacities in chest imaging. Bang Med J Khulna 2020: 53 : 13-16

Diagnostic and Prognostic Value of Routine Blood Tests in Patients with COVID-19 in Iran, Tehran

2021 ◽  
Author(s):  
Behzad Asanjarani ◽  
Goli Siri ◽  
Seyed Mahmoud Eshagh Hosseini ◽  
Hamed Abdollahi ◽  
Mehrdad Hasibi ◽  
...  
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Adverse Outcomes ◽  
Control Group ◽  
Laboratory Findings ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Routine Blood ◽  
Novel Coronavirus ◽  
Comprehensive Metabolic Panel

Background: Routine blood testing consists of Complete Blood Count (CBC) indices together with Comprehensive Metabolic Panel (CMP) which have significant roles in both diagnosis and prognosis of the novel coronavirus disease 2019 (COVID-19). Methods: A total number of 942 COVID-19 patients and 400 healthy persons as the control group were enrolled in this study. All patients were admitted to a single center and were divided into two groups according to disease severity (severe or non-severe). Routine laboratory findings of peripheral blood sample were collected and then analyzed. Results: Neutrophil-Lymphocyte Ratio (NLR) had the highest sensitivity and specificity value for COVID-19 diagnosis. Among patients with different severities of COVID-19, the amount of neutrophil, NLR, platelet, hemoglobin, Red cell Distribution Width (RDW) and total bilirubin was significantly different (p<0.01). Conclusion: Some indices of complete blood count and comprehensive metabolic panel have diagnostic and prognostic roles in COVID-19 patients, which are helpful in early diagnosis, predicting severity and adverse outcomes of patients with COVID-19.

scholarly journals Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Senol Kobak ◽  
Hatice Yilmaz ◽  
Murat Yalcin ◽  
Ahmet Karaarslan
Keyword(s):  
Rheumatoid Arthritis ◽  
Female Patient ◽  
Laboratory Tests ◽  
Morning Stiffness ◽  
Partial Regression ◽  
Digital Ulcer ◽  
Acute Phase Reactants ◽  
Laboratory Findings ◽  
Left Hand ◽  
Iloprost Infusion

42-year-old old female patient, followed up with diagnosis of rheumatoid arthritis for 15 years, was admitted with necrotising ulcer of left hand 1st and 2nd fingertips and pain, swelling, limitation of movement, and morning stiffness at bilateral wrist, and metacarpophalangeal and proximal interphalangeal joints. Laboratory tests revealed elevated acute phase reactants. Radial and ulnar arteries were clear in upper extremity Doppler ultrasound. The patient was diagnosed as RA activation and digital ulcer and administered iloprost infusion for five days and 1 mg/kg corticosteroid and 20 mg/week methotrexate (MTX). After one month, a partial regression of clinical and laboratory findings was observed. However, 6 months later, due to relapsed and increased complaints and findings, adalimumab 40 mg was administered. Two months later, clinical and laboratory findings apparently decreased.

P0899BIOMARKERS OF CKD-MBD IN CHILDREN

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Altynay Balmukhanova ◽  
Assiya Kanatbayeva ◽  
Kairat Kabulbayev ◽  
Abay Shepetov ◽  
Aigul Balmukhanova
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Correlation Analysis ◽  
Bone Metabolism ◽  
Laboratory Tests ◽  
Mean Value ◽  
Mineral And Bone Disorder ◽  
Number Of Patients ◽  
Bone Disorder ◽  
Fgf 23

Abstract Background and Aims In recent years there has been a growth in the number of patients with chronic kidney disease (CKD). As it is known, one of the most severe complications of CKD is mineral and bone disorder (MBD). MBD, which develops in childhood, contributes not only to the development of degenerative bone disease, but also to the growth of vascular morbidity and mortality in adulthood. Therefore, adequate control of bone and mineral metabolism is one of the goals in the treatment of children with CKD. Due to the recently discovered FGF-23, a significant role in the pathogenesis of MBD is given to hyperphosphatemia as the initiator of the process. However, changes in value of phosphorus and parathyroid hormone (PTH) are revealed only on the last stages of the disease. FGF-23 is a protein, which produced in bone cells and nowadays it is considered to be the central regulator of mineral-bone metabolism. It increases the loss of phosphorus in the urine due to the blockade of the sodium-phosphorus transporter in the proximal tubule of the nephron. FGF-23 also inhibits 1α-hydroxylase and stimulates 24-hydroxylase, leading to accelerated degradation of the active form of vitamin D. Thus, the aim of our study was to investigate the relation between FGF-23 and other markers of bone metabolism such as phosphorus and parathyroid hormone. Method The study was conducted on 73 children (38 boys and 35 girls) with different stages of CKD. An average age of the patients was 9.89 ± 0.57 years. Exclusion criteria: active inflammatory, bone, infectious, oncological, immunological diseases; taking steroids and vitamin D supplements. We performed further laboratory tests: phosphorus, PTH, vitamin D and FGF-23. Serum concentration of intact FGF-23 was assessed by using the kit for ELISA method (Biomedica Medizinprodukte GmbH, Austria). This study was approved by the local scientific ethics committee of National medical university. Ethical standards and rights of patients were not violated. Descriptive statistics and correlation analysis were performed in MS Excel 2016 and SPSS 18.0. Results The laboratory tests results revealed that the mean value of phosphorus was 1.77±0.04 mmol/l among all patients with different stages of CKD. There were 29 (33.3%) children with hyperphosphatemia. The most of these patients were ESRD and they needed a renal replacement therapy. No patients with CKD 1-3 stages had high level of phosphorus. The values of PTH increase as CKD progresses. The patients with the first and second stages had absolutely normal PTH value and only 2 patients with the third stage had slightly elevated level. Only 1 out of 17 patients on dialysis (both hemodialysis and peritoneal dialysis) had an acceptable PTH value. By contrast, there was a vitamin D deficiency (a mean value was 22.4±1.64 ng/ml). The results of identification FGF-23 by the ELISA kit showed that there was also a gradual increase in its level depending on the stage of the disease. Moreover, there were 14 (19.2%) children with elevated FGF-23 concentration though other markers of bone metabolism were normal. The correlation analysis revealed positively significant associations between FGF-23 and phosphorus (r=0.60, p=0.00), FGF-23 and PTH (r=0.68, p=0.00). Conclusion Overall, our investigation proved that FGF-23 is positively correlated to phosphorus and PTH. Furthermore, in most cases, FGF-23 responds much sooner than other markers of mineral and bone metabolism and its increased value might be an early predictor of mineral and bone disorder. However, more research is required in this area.

scholarly journals To Compare Neutrophil Lymphocyte Ratio with Other Parameters in Acute Exacerbation of COPD and Stable COPD: A Hospital Based Study

2020 ◽  
Vol 9 (1) ◽  
pp. PM20-PM23
Author(s):  
Kailash Sharma ◽  
Gajendra Singh ◽  
Ummed Singh
Keyword(s):  
Acute Exacerbation ◽  
Complete Blood Count ◽  
Cost Effective ◽  
Mean Value ◽  
Normal Range ◽  
Acute Exacerbation Of Copd ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Wbc Count ◽  
Exacerbation Of Copd

Background: White blood cell (WBC) count and its subtypes are also well known systemic inflammatory markers. The ratio of neutrophils to lymphocytes (NLR), which is calculated from complete blood count with differential, is an inexpensive widely available marker of inflammation. The aim of this study to compared the neutrophil lymphocyte ratio with other parameters in acute exacerbation of COPD and stable COPD.Subjects and Methods:A Hospital based comparative study done on 50 Patients with COPD (stable/ exacerbation) attending at Government Medical College, Bharatpur, Rajasthan. While the upper limit of neutrophils count for normal range was set at 8x109/l, the lower limit of lymphocyte count for the normal range was set at 0.9x109/l. NLR was calculated as the ratio of neutrophils to lymphocytes, both of which were obtained from the same automated blood samples for the study.Results:Our study showed that the comparison of mean value of age, BMI & pack years was statistically significant (P=0.0112, P<0.0001 & P=0.0141 respectively) in between groups. The comparison of mean value of NLR was statistical significant (P=0.0009) in between groups. NLR measurement demonstrated a sensitivity and specificity of 40%and 77.14%. PPV and NPV for NLR were 63.64%and 56.25%, and OR and RR were 2.250 and 1.455. A positive correlation was determined between NLR and CRP (r=0.482; p<0.05).Conclusion: NLR, like CRP, both readily available and simple parameters, could also be used as a cost-effective marker of inflammation in AECOPD.

Von Willebrand Disease in Taiwan: A Clinical and Laboratory Studies of 52 Patients.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 3974-3974
Author(s):  
Yeu-Chin Chen ◽  
Tsu-Yi Chao ◽  
Shin-Nan Cheng
Keyword(s):  
Laboratory Tests ◽  
Invasive Procedure ◽  
Mean Value ◽  
Von Willebrand Disease ◽  
Type I ◽  
Excessive Bleeding ◽  
Disease Subtype ◽  
Dental Procedures ◽  
Number Of Patients ◽  
Von Willebrand

Abstract Von Willebrand disease (VWD) has been found to be the most common inherited bleeding disorder in Caucasian with a prevalence of around 1%, yet it has not been well recognized in Taiwan and Asian countries. Only a small number of patients have been identified and reported. The aim of this retrospective study was to identify patients with VWD by clinical manifestation and laboratory tests in Taiwan. VWD was detected by a panel of laboratory tests, including bleeding time, aPTT, factor VIII activity assay, Von Willebrand antigen (VWF: Ag) and ristocetin cofactor activity (VWF: RCo), and platelet function analyzer (PFA) test using both Collagen/ADP and Collagen/Epinephrine (CEPI). VWF multimer analysis was performed by western blot to confirm the disease subtype. From October, 2003 to April, 2007, 52 of 494 (9.5%) patients, from 44 families, were identified to have VWD, including 16 men and 36 women. Their median age was 29 with a range of 4∼69 years of age. The most frequently encountered reasons for VWD detection was menorrhagia accounting for 19.2%. The others included inherited detection because of affected family (11.5%), prolonged aPTT (11.5%), excessive bleeding after dental procedures (9.6%) and excessive bleeding after surgery or invasive procedure (9.6%). By laboratory tests, the mean value of VWF: Ag and VWF: RCo was 46.9 ± 18.4% and 32.3 ± 17.4%, respectively. The most sensitive test was VWF: RCo with 90.3%, followed by CEPI with 83.8%. Of 37 patients with VWF multimer analysis, 34(92%) were revealed to have type I VWD, 1 had type IIA, and 2 from the same family had type III VWD. In conclusion, our study demonstrated that VWD was not an uncommon inherited bleeding disease in Taiwan. Menorrhagia was the most common reason for VWD determination, and VWF: RCo and PFA test CEPI were the more sensitive tests for the VWD identification.

scholarly journals AB0782 MONOARTHRITIS: PROBABLE OUTCOMES

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1417.1-1417
Author(s):  
M. Osipyan ◽  
M. Efraimidou ◽  
V. Vardanyan ◽  
K. Ginosyan
Keyword(s):  
Joint Distribution ◽  
Complete Blood Count ◽  
Mefv Gene ◽  
Baseline Data ◽  
Mefv Mutations ◽  
Appropriate Treatment ◽  
Number Of Patients ◽  
Female Predominance ◽  
Mediterranean Fever ◽  
Systemic Manifestations

Background:Numerous joint disorders initially produce swelling in a single joint and new onset monoartritis will probably further lead to the involvement of other joint groups and development of extraarticular manifestations. It is essential to take a proper diagnostic approach for organizing appropriate treatment and lowering possibility of disease progression.Objectives:The aim of this study was to investigate joint distribution, determine rheumatological diseases of patients with acute monoarthritis and reveal the development of further systemic manifestations.Methods:100 patients (age 18-75 years) with clinically apparent monoarthritis of less than 6 weeks duration were included in the study. Criteria of exclusion were infection, trauma and crystal induced arthritis. Joint distribution, presence of systemic manifestations and development of chronic inflammatory rheumatic disease were evaluated. Presence of arthritis was proved with help of ultrasound examination. Complete blood count, ESR, CRP, RF, anti-CCP; HLAB27; MEFV mutations and X-ray of swollen joint were performed for all patients. Temperature was also measured.Results:Mean age of patients with acute monoarthritis was 46±13 years. Female predominance was noted (61%). 71% of patients had elevated ESR, 69%- CRP. In 24% of cases homozygous or heterozygous mutations of MEFV gene were revealed. 21% of patients had positive RF and 18% - anti-CCP. 11% patients carried HLA-B27 antigen. 28% of examined patients had subfebril fever. Hepatosplenomegaly was determined in 16%, uveitis in 5%, psoriatic plaque in 4%, interstitial pneumonia in 2% of casesAt the baseline 82 patients were diagnosed with rheumatologically disease. Baseline data is shown in the Table 1 bellow.Table 1.Baseline dataDiagnosis Number of patientsFMF23Osteoarthritis (reactive synovitis)16Rheumatoid arthritis15Reactive arthritis10Ankylosing spondylitis6Psoriatic arthritis4SLE3Schonleyn-Henoch purpura2Sarcoidosis2Behcet diseases1Conclusion:In this study monoarhtritis in majority of cases underlies FMF. Though FMF is not considered as a frequent cause of acute monoarthritis, more attention should be paid on this pathology in focus of monoarthritis, especially in specific for FMF region. Further follow up of acute monoarthritis progression is needed.References:[1]A. Becker, J. Daily, K. Pohlgeers. Acute Monoarthritis: Diagnosis in Adults.Am Fam Physician 2016; 94(10): 810-816[2]S. Camacho-Lovillo, A. García-Martínez. Arthritis as presentation of familial Mediterranean fever. An Pediatr (Barc). 2015; 83(2):130. DOI: 10.1016/j.anpede.2015.07.007[3]J. Ellis. Acute monoarthritis. JAAPA. 2019, 32(3):25-31. doi: 0.1097/01.JAA.0000553379.52389.ebDisclosure of Interests:None declared

scholarly journals Relative Frequency and Risk Factors of COVID-19 Related Headache in a Sample of Egyptian Population: A Hospital-Based Study

Pain Medicine ◽  
2021 ◽  
Author(s):  
Mona Hussein ◽  
Wael Fathy ◽  
Ragaey A Eid ◽  
Hoda M Abdel-Hamid ◽  
Ahmed Yehia ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Platelet Count ◽  
Relative Frequency ◽  
Clinical Laboratory ◽  
Primary Headache ◽  
Female Gender ◽  
Imaging Data ◽  
Laboratory Findings ◽  
Neutrophil Lymphocyte Ratio ◽  
The Impact

Abstract Objectives Headache is considered one of the most frequent neurological manifestations of coronavirus disease 2019 (COVID-19). This work aimed to identify the relative frequency of COVID-19-related headache and to clarify the impact of clinical, laboratory findings of COVID-19 infection on headache occurrence and its response to analgesics. Design Cross-sectional study. Setting Recovered COVID-19 patients. Subjects In total, 782 patients with a confirmed diagnosis of COVID-19 infection. Methods Clinical, laboratory, and imaging data were obtained from the hospital medical records. Regarding patients who developed COVID-19 related headache, a trained neurologist performed an analysis of headache and its response to analgesics. Results The relative frequency of COVID-19 related headache among our sample was 55.1% with 95% confidence interval (CI) (.516–.586) for the estimated population prevalence. Female gender, malignancy, primary headache, fever, dehydration, lower levels of hemoglobin and platelets and higher levels of neutrophil/lymphocyte ratio (NLR) and CRP were significantly associated with COVID-19 related headache. Multivariate analysis revealed that female gender, fever, dehydration, primary headache, high NLR, and decreased platelet count were independent predictors of headache occurrence. By evaluating headache response to analgesics, old age, diabetes, hypertension, primary headache, severe COVID-19, steroid intake, higher CRP and ferritin and lower hemoglobin levels were associated with poor response to analgesics. Multivariate analysis revealed that primary headache, steroids intake, moderate and severe COVID-19 were independent predictors of non-response to analgesics. Discussion Headache occurs in 55.1% of patients with COVID-19. Female gender, fever, dehydration, primary headache, high NLR, and decreased platelet count are considered independent predictors of COVID-19 related headache.

scholarly journals Mild bleeders: Diagnosis is elusive in large number of patients

2016 ◽  
Vol 8 ◽  
pp. 201649 ◽  
Author(s):  
Mrinalini Kotru ◽  
Deepti Mutereja ◽  
Abhishek Purohit ◽  
Seema Tyagi ◽  
Manoranjan Mahapatra ◽  
...  
Keyword(s):  
Platelet Function ◽  
Complete Blood Count ◽  
Bleeding Tendency ◽  
Thrombin Time ◽  
Bleeding Disorders ◽  
Platelet Aggregometry ◽  
Number Of Patients ◽  
Pertinent Question ◽  
Common Clinical Presentation ◽  
A Prospective Study

Abstract. Background: Bleeding is a common clinical presentation. Even patients with mild bleeding disorders are extensively investigated for ascertaining the cause. The present study was conducted in order to evaluate the extent of the possibility of diagnosis in mild bleeding disorders.Material and Methods: This was a prospective study of patients referred for work up of mild bleeding for a period of 13 months. A complete blood count, peripheral smear examination, Prothrombin time, Partial Thromboplastin time and Thrombin Time, Platelet Aggregometry test, tests for von Willebrand’s disease and Platelet function 3 availability were measured. Results: 164 patients presented with mild bleeding, in 114 of the  patients a single site of bleeding was present. Epistaxis was the most common presentation (39%). Cutaneous bleeding (petechiae and purpura) was the next common site. History of a major bleeding tendency in the family was present only in 11 patients. The investigations showed that VWD (17/164), followed by clotting disorders (CD) mainly mild hemophilia (15/164) were the most common diagnosable cause. There were also 4 cases of hypofibrinogenemia. The disorders of platelets (Platelet function defects/PFD) were the least common (9/164). Rest 123 (75%) patients could not be diagnosed on the basis of these investigations and were labeled as  Bleeding disorders – Unclassified (BDC). Conclusion: n our study, 75% of the patients with mild bleeding remained undiagnosed even after extensive laboratory workup, thus raising a very pertinent question that is it necessary that all mild bleeders submit to a broad battery of investigations, as the diagnosis continues to be elusive despite extensive workup.

scholarly journals The Role of Transthoracic Ultrasound in the Study of Interstitial Lung Diseases: High-Resolution Computed Tomography Versus Ultrasound Patterns: Our Preliminary Experience

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 439
Author(s):  
Donato Lacedonia ◽  
Giulia Scioscia ◽  
Angelamaria Giardinelli ◽  
Carla Maria Irene Quarato ◽  
Ennio Vincenzo Sassani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
High Resolution Computed Tomography ◽  
Pleural Line ◽  
Complementary Role ◽  
Number Of Patients ◽  
Significant Difference ◽  
Transthoracic Ultrasound

Transthoracic ultrasound (TUS) is a readily available imaging tool that can provide a quick real-time evaluation. The aim of this preliminary study was to establish a complementary role for this imaging method in the approach of interstitial lung diseases (ILDs). TUS examination was performed in 43 consecutive patients with pulmonary fibrosis and TUS findings were compared with the corresponding high-resolution computed tomography (HRCT) scans. All patients showed a thickened hyperechoic pleural line, despite no difference between dominant HRCT patterns (ground glass, honeycombing, mixed pattern) being recorded (p > 0.05). However, pleural lines’ thickening showed a significant difference between different HRCT degree of fibrosis (p < 0.001) and a negative correlation with functional parameters. The presence of >3 B-lines and subpleural nodules was also assessed in a large number of patients, although they did not demonstrate any particular association with a specific HRCT finding or fibrotic degree. Results allow us to suggest a complementary role for TUS in facilitating an early diagnosis of ILD or helping to detect a possible disease progression or eventual complications during routine clinical practice (with pleural line measurements and subpleural nodules), although HRCT remains the gold standard in the definition of ILD pattern, disease extent and follow-up.

Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Esin Merve Erol Koç ◽  
Rahime Bedir Fındık ◽  
Hatice Akkaya ◽  
Işılay Karadağ ◽  
Eda Özden Tokalıoğlu ◽  
...  
Keyword(s):  
Complete Blood Count ◽  
Perinatal Outcomes ◽  
Control Group ◽  
Strong Positive Correlation ◽  
Monocyte Count ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Significant Difference ◽  
Adverse Perinatal Outcomes

AbstractObjectivesTo evaluate the relationship between Coronavirus Disease 2019 (COVID-19) in pregnancy and adverse perinatal outcomes. The secondary aim is to analyze the diagnostic value of hematologic parameters in COVID-19 complicated pregnancies.MethodsThe current study is conducted in a high volume tertiary obstetrics center burdened by COVID-19 pandemics, in Turkey. In this cohort study, perinatal outcomes and complete blood count indices performed at the time of admission of 39 pregnancies (Study group) complicated by COVID-19 were compared with 69 uncomplicated pregnancies (Control group).ResultsThere was no significant difference between the obstetric and neonatal outcomes of pregnancies with COVID-19 compared to data of healthy pregnancies, except the increased C-section rate (p=0.026). Monocyte count, red cell distribution width (RDW), neutrophil/lymphocyte ratio (NLR), and monocyte/lymphocyte ratio (MLR) were significantly increased (p<0.0001, p=0.009, p=0.043, p<0.0001, respectively) whereas the MPV and plateletcrit were significantly decreased (p=0.001, p=0.008) in pregnants with COVID-19. ROC analysis revealed that the optimal cut-off value for MLR was 0.354 which indicated 96.7% specificity and 59.5% sensitivity in diagnosis of pregnant women with COVID-19. A strong positive correlation was found between the MLR and the presence of cough symptom (r=41.4, p=<0.0001).ConclusionsThe study revealed that, pregnancies complicated by COVID-19 is not related with adverse perinatal outcomes. MLR may serve as a supportive diagnostic parameter together with the Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) in assessment of COVID-19 in pregnant cohort.

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