scholarly journals Clinical presentation of ulcerative colitis among Bangladeshi population twenty years experience from a tertiary care hospital in Bangladesh

2016 ◽  
Vol 6 (1) ◽  
pp. 16
Author(s):  
Mohammad Shoaib Chowdhury ◽  
Md. Masudur Rahman Khan ◽  
Md. Zahidur Rahman ◽  
Madhusudan Saha ◽  
Guru Prashad Dhakal ◽  
...  

<p><strong>Background:</strong> The prevalence of Ulcerative colitis has been increasingly reported from Western countries as well as other Asian countries. Our personal experience shows that Ulcerative colitis is not uncommon in our country and is being diagnosed more commonly. So, there is need to study the disease pattern in our country. Objective: To find out the clinical presentation, among Bangladeshi population. <strong></strong></p><p><strong>Methods:</strong> A hospital (Department of Gastroenterology, Bang­abandhu Sheikh Mujib Medical University) based study registering previously diagnosed and newly diagnosed cases of Ulcerative colitis, was carried out from January 1990 to June 2010. Data that were obtained are: age and sex of the patients, clinical presentations like bloody diarrhoea, per rectal bleeding, diarrhoea without per rectal bleeding, urgency, tenesmus, abdominal pain, fever, anorexia, weakness, weight loss. Data regarding physical findings and extra intestinal manifestations were also recorded. <strong></strong></p><p><strong>Results:</strong> Out of 164 patients 65.24% (107) were male and 34.76% (57) were female. The male- female ratio was 1.88 : 1. Mean age of male patients was 36.14(±11.66) years and mean age for female patients was 33.15(±11.12) years. Maximum number of male patients were in 21-40 years age group (65.42%, 70). Maximum number of female patients were in 21-30 years age group (42.10%, 24). Maximum number of both male and female patients were in 21-30 years age group (35.97%, 59). Clinical features of 164 patients showed that 87.28% (143) had bloody diarrhoea, 20.12% (33) had per-rectal bleeding, 4.26% (7) had diarrhoea without per rectal bleeding, 1.21% (2) had urgency, 5.48% (9) had tenesmus, 33.53% (55) had abdominal pain, 17.66% (29) had fever, 18.29% (30) had anorexia, weakness and 17.68% (29) had weight loss at their initial presentation. Physical examination of 164 patients revealed that 81(49.39%) patients had normal findings, 7 (4.27%) patients had oedema and 83 (50.61%) patients had anaemia. Extra intestinal features were absent in 143 (87.20%) patients out of 164 patients. The rest 21 (12.80%) patients had joint involvement and 2 ( 1.21 % ) patients had ocular involvement. There was no patient with skin involvement. <strong></strong></p><p><strong>Conclusion:</strong> The clinical presentation of Ulcerative colitis in our country is mostly similar compared to other Asian' and Western countries except higher male-female ratio, presence of oedema and wide variability of extra intestinal involve­ment. These differences are probably due to social and cultural reasons, poor nutritional status, incomplete workup or records and influence of various enviornmental factors. To validate these results further prospective studies are needed.</p>

2018 ◽  
Vol 29 (1) ◽  
pp. 16-20
Author(s):  
MMR Khan ◽  
NK Sana ◽  
PM Basak ◽  
BC Sarker ◽  
M Akhtarul Islam ◽  
...  

Background: The impacts of socio-demographic characteristics on acute myocardial infarction (AMI) are not well understood and have not yet been studied much more in our country. Acute myocardial infarction is the most common form of coronary heart disease and the single most important cause of premature death worldwide.Objective: The aim of this study was to assess the impacts of the socio-demographic characteristics on AMI patients and to investigate the association between socioeconomic status and its various indicators and the risk of acute myocardial infarction (AMI). This study will help in awareness building in reducing AMI by early detection of socio-demographic variables.Patients and methods: This was a prospective observational study consisted of 325 persons of AMI patients who were aged >20 years. Patients with first time AMI arriving in Coronary Care Unit (CCU) of Rajshahi medical college during the period of 2012-2014, were included. Data were collected through interview.Results: Among the AMI patients, male were more sufferer than female (68.3% vs. 31.7%) and male and female ratio was 2.15:1.0. Highest percentage of education was up to primary level (53.85%). Most of studied subjects (92.0%) monthly income were ≤15000. More than half (59.38%) of the studied population were from rural area, mostly they were Muslim (94.46%) and smokers (50.15%). The mean±SD age of the acute Myocardial infarction patients was 53.75±11.64 years. Mean age of the female patients were a little bit higher than the male patients (female 54.28±11.78 vs. male 53.51±11.63). Highest percentage was in the age group 51-60 years (32%) followed by 41-50 (26.8%) and then age group >60 (23.7%). Among the male patients highest percentage was in the age group 51-60 years (31.1%) followed by 41-50 years (27%) and then age group >60 (24.3%). However, among the female patients, highest percentage were in the age group 51-60 years (34%) followed by 41-50 years (26.2%), and then age group >60 (22.3%). Acute Myocardial infarction patients was more in age group >40 years of age. Interestingly after 60 years of age occurrence of AMI was low in both sexes.Conclusion: Both sex and age influenced AMI. An association was also found among educational level, monthly income, residence area, religion, smoking habit and AMI.TAJ 2016; 29(1): 16-20


2011 ◽  
Vol 26 (S1) ◽  
pp. s27-s28
Author(s):  
M. Hata ◽  
J. Tanaka ◽  
Y. Yamahata ◽  
K. Okuchi

An earthquake struck Haiti on 12 January 2010. More than 200,000 people were killed and more than 300,000 people were injured in this earthquake. The Japanese government dispatched the Japan Disaster Relief Medical Team (JDR-MT) to Haiti on 16 January. This is the report of the medical activities of JDR-MT in Haiti. The JDR-MT consisted of 27 members, including four medical doctors, seven nurses, one pharmacist, one radiologist, one medical technologist, two emergency medical technicians, and 11 logisticians. The JDR-MT was equipped with medicines for 1,000 patients, a portable x-ray system, and ultrasound diagnostic equipment. The JDR-MT performed relief activities at Leogane City, which was 40km west of the capital of Port-au-Prince, and was the first medical team that entered the Leogane area after the earthquake. The JDR-MT treated 534 patients for eight days. The male-female ratio of total patients was 180/354, and the male-female ratio of 242 injured cases treated by the JDR-MT was 80/162. Among the patients treated by the JDR-MT, 100 were diagnosed as bone fractures with the portable x-ray system. There were 17 cases of open bone fractures and 15 cases of pelvic fractures. The male-female ratios were 28/72, 4/13, and 1/14 respectively. The total number of female patients was approximately double compared with the number of male patients in this experience. The proportion of female patients was much higher in the cases of severe injury, such as open bone fractures and pelvic fractures.


Author(s):  
Maneesha Sethi ◽  
Ridham Nanda ◽  
Amarjeet Singh Bali ◽  
P. Sadhotra

Background: Vernal Keratoconjunctivitis (VKC) is common cause of ocular morbidity in children living in tropical countries. Its diagnosis is based on signs and symptoms of the disease. The study was undertaken to stress upon the demography and clinical presentation of VKC.Methods: Retrospective pre-formed proforma of 155 patients of VKC, who were detected at random in the out - patient department of ophthalmology, ASCOMS, Jammu from May 2016 to April 2017, were analyzed.Results: Mean age at presentation was 10.31 years +4.05. The Male: Female ratio was 4.96:1. Majority of patients reported in the month of May. Mixed type of VKC was predominant. Personal or family history of allergy was seen in 5.8% of patients. Itching (100%) was commonest symptom and palpaberal papillae were commonest sign seen in 78.70% of patients.Conclusions: Clinical pattern of VKC seen in hot and dry climate of Northern India is like that seen in other parts of country.


2014 ◽  
Vol 15 (2) ◽  
pp. 118-121
Author(s):  
Aparna Das ◽  
Modhusudan Saha ◽  
Bimal Chandra Shil ◽  
Rubina Yasmin ◽  
Gobinda Banik ◽  
...  

Background: The pattern and incidence of Carcinoma Stomach vary widely in different parts of the world. Overall it is the 2nd most common cause of death but in some Asian countries, it is still the commonest cause of cancer death in patients of > 50 years.Aim: To analyze the clinical presentation and histological findings of patients of carcinoma of the stomach. Methods and materials: This study was done over a period of 2 years between January 2011 and December 2012. Adult patients (Age more than 18 years) of histologically confirmed as having carcinoma stomach were included in the study. Studied variables included age, gender, socioeconomic status, clinical presentations, site of lesion, histopathological subtypes. Diagnostic modalities included abdominal ultrasound, upper GI (gastrointestinal) endoscopy and endoscopic biopsy to confirm the diagnosis. Results: Total number of patients included in this study was 150. The number of patients in <50 years age group and >50 years age group were 50 (33.33%) & 100 (66.66%) respectively. The median age at presentation was 57 years. The peak incidence was in 61-70 years age group. In our study,male: female ratio being 2.3:1. By occupation, farmer 74 (49%), housewife 37(24.6%), serviceholder12(8%), business man 5(10%) and others12 (8%). 71 (47.4%) patients were from lower socioeconomic group, middle74 (49.4%), upper class 5 (3.4%) & only 63 (42%) were literate. The common clinical features were vomiting 28%, abdominal pain 18%, weight loss and anorexia 17.3% , dyspepsia 16% , Anaemia (26% ), Abdominal mass 4%, Metastatic lymph node 4%, Ascites 1.3%. lesions are involved in Cardia 14%, Body &Antrum 6.6%, Antrum 2.6%, Body 23.3%, Fundus 2% and Diffusely in 1.3% cases. Conclusion: As regards to clinical presentation, patients in our country are presenting more with features of gastric outlet obstruction whereas abdominal lump and upper GI bleeding are more common in Western world. If gastric carcinoma is diagnosed at an early stage, patients can have a highly favorable prognosis.DOI: http://dx.doi.org/10.3329/jom.v15i2.20683 J MEDICINE 2014; 15 : 118-121


2015 ◽  
Vol 14 (1) ◽  
pp. 36-37
Author(s):  
Mozammel Hoq Sharife ◽  
M Jalal Uddin ◽  
Mostak Ahmed

Objective: The study was conducted to evaluate outcome of probing for congenital nasolacrimal duct obstruction. It was an interventional study at a tertiary level hospital of Chittagong. Methods: The study was conducted during April 2009 to March 2013 (04 years). Total 120 eyes of 102 children of 1-3 years age group were probed. Minimum follow up time was 01 year. Results: 110 eyes fully cured, 05 eyes needed re-probing, 03 eyes needed Dacrocystorhinostomy operation (DCR) and 02 cases were dropped out. Male female ratio was 72 (60%) and 48 (40%). Conclusion: Outcome of probing is better among 1-2 years age group than that of 2- 3 years age group. A discussion is made with updated literature review. DOI: http://dx.doi.org/10.3329/cmoshmcj.v14i1.22879 Chatt Maa Shi Hosp Med Coll J; Vol.14 (1); Jan 2015; Page 36-37


2020 ◽  
Vol 6 (1) ◽  
pp. 81-93
Author(s):  
Mijala Bajracharya ◽  
S Nakarmi

Correction: The page numbers were changed from 98-100 to 81-93 on 31/08/2020. Background: Obesity is regarded as worldwide health problems which may put a person at a higher risk of serious health conditions leading to morbidity and mortality. Obesity is a risk factor for many diseases of which hypertension and type-2 diabetes mellitus are the most important. Hypertension, diabetes mellitus and obesity together form 24% of the global risk for mortality. Cardiovascular diseases related to these life-style disorders has major effect on life expectancy and impaired quality of life. Objectives: The study was done to evaluate the drug prescribing pattern of type - 2 diabetes and hypertension in both obese and non-obese patients. Along with it, this study also attempt to find the contributing factors associated with it and different types of drugs selected in those conditions respectively. Method: A descriptive cross-sectional study was conducted in 2074 at Manmohan memorial teaching hospital. A total of 101 out-patient were interviewed, measurements were done to calculate BMI and waist to hip ratio and their prescriptions were reviewed. For Treatment Guideline of HTN, JNC 8[20] was followed and Updated Treatment Guidelines for Type 2 Diabetes by the American Diabetes Association (ADA) [21] was followed in case of diabetes. Result: Among 101 patients studied, 58 were males and 43 were females. Regarding physical activity, only 26.7% of total patients were involved in morning walk and 3% in yoga, remaining 71% of study patients did not involve in any kind of physical exercise. Regarding food habits, 22.8% were smokers, 49.5% were alcoholics and 96% were non-vegetarians. Waist to hip ratio was also observed higher in both males (35.6%) and females (39.6%). Among the101 total participants, the age group of 41-55 years were found to be more obese than other age group (34 in numbers) followed by age group 56-70 which were 16 in numbers. Male patients were more obese (41) than female patients (31). Highest number (31) of the obese patients were diagnosed with type 2 diabetes mellitus, followed by second highest number (26) of patients diagnosed with hypertension and 15 patients with both the conditions. The commonly prescribed oral hypoglycemic drugs were metformin (35.60%) followed by glimepiride (24.80%). Among anti-hypertensive drugs, amlodipine (22.80%) was most common in prescriptions followed by losartan (18.80%) and Telmisartan (17.80%). Conclusion: The results of the present study show that higher number of male patients (41) were obese than female patients (31). About 30% of patients were found obese-diabetic, 26% were obese-hypertensive and 15% were with both obese diabetic and hypertensive condition. Among oral hypoglycemic drugs, metformin (35.60%) was mostly prescribed followed by glimepiride (24.80%). Among antihypertensives, amlodipine (22.8%) was mostly prescribed followed by losartan (18.80%). Atorvastatin (11.9%) was mostly prescribed oral hypolipidemic agent.


2019 ◽  
Vol 27 (2) ◽  
pp. 113-120
Author(s):  
Sabyasachi Ghosh ◽  
Tarak Nath Saha ◽  
Indranil Sen

Introduction   Head and neck lesions encompass a multitude of disorders which can be broadly classified into two groups: Benign and Malignant. Overall 57.5% of global head and neck cancers comes from Asia itself and India alone constitutes 30% of it. Therefore, it is of prime essence that need based and coordinated research for understanding the threats to the nation from chronic diseases such as head and neck cancers and ways to defy such threats should gain the utmost importance. The present study attempts to present the epidemiological profile of the patients attending a peripheral referral institute of this state with head-neck pathologies and has undergone a histopathological examination of their lesions within a period of three years period (2016-18) based on the histopathological evidences. Materials and Methods The accumulated data regarding the aforesaid patients as per records of the histopathological reports available in the Department of Pathology was used as the primary material and the interrelation of different epidemiological parameters were studied using the statistical methods Results Six hundred and eighty seven cases from the head and neck region were analysed during this three-year period. Age range was from 3 years to 96 years with maximum cases in the age group of 20-29 years (16.1%). The Male: Female ratio in our study was 1.34:1 (Males 394, Females 293). In this study, 38.8% benign, 32.46% malignant, 25.32% inflammatory and 3.3% congenital cases were recorded. Maximum number of benign lesions was in the age group of 10-39 years. Malignancies were noted to be higher in ages 40 years and above. Squamous cell carcinoma was the most common malignancy observed. Conclusion  Specific data obtained like this from histopathological records is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.


Author(s):  
Irda Handayani ◽  
B. Rusli ◽  
Hardjoeno Hardjoeno

Nephrotic syndrome (NS) is characterized by proteinuria, hypoalbuminemia accompanied by oedema and hypercholesterolemia.Nephrotic syndrome is an often relapsing disease (75%) and often the diagnosis is too late. This disease is 15 times greater in childrenthan in adult and the male to female ratio is 2:1. Laboratory examination is needed to rapidly detect and evaluate the progress of thedisease for treatment. To know the distribution of NS based on aged, gender, cholesterol, and albumin concentration and the urinesediment profile. The data in this retrospective descriptive study were collected from 56 patients with NS at the Wahidin SudirohusodoHospital, Makassar, in the period of January 2004 – June 2006. NS were found in 36 male patients (64.3%) and 20 female patients(35.7%). Cholesterol concentrations were 250 mg/dl in 50 patients (89.3%) and 250 mg/dl in 6 patients (10.7%). Albuminconcentration was 2.5 g/dl in 21 patients (37.5%) and < 2.5 gr/dl in 35 patients (62.5%). In urine sediments, there were found in 23patients (41.1%) with positive proteinuria (+++), 51 patients (91.1%) with positive erythrocytes, 54 patients (96.4%) with positiveleucocytes, and 33 patients (58.9%) with positive cylinders such as rugged granular and fatty cost. More NS were found in male patientsin comparison to female, and many were aged + 6 years. Hypercholesterolemia, hypoalbuminemia, proteinuria, hematuria, leucocyturia,and positive cylinder (rugged granular and fatty cast) were found in the urine of most of the NS patients.


2017 ◽  
Vol 3 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Md Shafiul Alam ◽  
Md Abdus Salam ◽  
Tayseer Farzana ◽  
ASM Raushan Newaz ◽  
Md Saiful Islam

Background: Spinal tuberculosis is more frequently reported in developing countries.Objective: The purpose of the present study was to see the socio-demographic characteristics of spinal tuberculosis patients.Methodology: This study was carried out in the Department of Neurosurgery, Dhaka Medical College Hospital during the period of January 2002 to December 2004 to elucidate the effectiveness of surgical and conservative treatment of the tuberculosis of the spine. For this purpose, a total number of 50 consecutive cases admitted during the study period with tuberculosis of the spine supported by investigations were included in this study.Result: The mean age of the patients was 25.4 years and ranged from 7 years to 68 years. The highest incidence of tuberculosis of the spine was found in age group between 11 to 20 years and 70% of the patients were under 30 years of age. Incidence of tuberculosis of this spine was more in male (62%) in comparison to female (3 8%) with a male female ratio of 1.63:1. In this study most of the patients came from low class society (66%) followed by middle class (28%) and high class (6%) respectively.Conclusion: Spinal TB more frequently occurs among the young age group with a male predominance.Bangladesh Journal of Infectious Diseases 2016;3(1):3-5


Author(s):  
Rukma L. Sharma ◽  
Rekha Sharma

<p class="abstract"><strong>Background:</strong> Herpes zoster results from the reactivation of varicella-zoster virus lying dormant in the dorsal root ganglia following an earlier primary infection (chickenpox), usually in childhood. The reactivation occurs due to multifactorial causes leading to decreased immunity.</p><p class="abstract"><strong>Methods:</strong> This study was conducted on 109 cases of herpes zoster. Patient’s particulars were noted. A detailed history was recorded; morphology, the site and side of skin lesions were recorded. Any other associated diseases were noted.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 109 patients 66 were male and 43 were female. The total of 53 (48.6%) patients were under the age of 40 years and 56 (51.4%) patients above 40 years. Bhutias were affected in highest number (18.4%) followed by Sharma community (15.6%). The ophthalmic division of trigeminal nerve was the most commonly affected single nerve with 13.8% followed by T10 and T7 dermatome at 9.17% and 7.3% respectively. Thoracic nerves the most commonly involved thoracic nerves with 44 cases. Single dermatomal eruptions were found in 55 patients. The dissemination of herpes zoster was although very rare but was present in three patients. Type 2 diabetes mellitus was the common associated systemic illness with 10.09% of patients.</p><p class="abstract"><strong>Conclusions:</strong> From this study it was revealed that both young adults and older age group people were affected almost equally. The male: female ratio was 1.5:1 with Bhutia community being mostly affected. Thoracic dermatome was the most common dermatome involved and in half the patients some form of associated disease noted.</p>


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