scholarly journals Treatment Response on Positive Symptoms of Schizophrenia with Olanzapine and Risperidone

2020 ◽  
Vol 15 (1) ◽  
pp. 58-60
Author(s):  
Fatema Zerin Khan ◽  
Nafisa Rashid ◽  
Syeda Papia Sultana ◽  
Wahida Rahman ◽  
Sayeda Nazrina ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Armed Forces ◽  
Treated Group ◽  
Positive Symptoms ◽  
Inclusion Criteria ◽  
Medical College ◽  
Motor Behaviors ◽  
Disturbed Behavior ◽  
The Difference ◽  
Medical University

Introduction: Positive symptoms become perceptible in patients as schizophrenia progresses. If schizophrenia goes untreated catatonic motor behaviors are develops. Now a day’s catatonia which is a type of disturbed behavior is observed, with less frequency than in past years due to advances in treating schizophrenia. Treatment of schizophrenia by olanzapine and risperidone shows diverse outcomes. Objectives: To assess the response on positive symptoms of schizophrenia by olanzapine and risperidone. Materials and Methods: This study was conducted in Department of Pharmacology and Department of Psychiatry of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period from September 2013 to January 2015. A total of 179 schizophrenia patients fulfilling the inclusion criteria were enrolled and of them 75 patients completed the study, where 40 were in olanzapine treated group and 35 were in risperidone treated group in a 12-weeks assessment where Scale for Assessment of Positive Symptoms (SAPS) was applied. After statistical analysis of scores between intergroup and intra group p<0.05 was considered significant. Results: Treatment with both the olanzapine and risperidone were remarkably effective for progress of positive symptoms of schizophrenia patients but in olanzapine treated group the score was reduced more than that of risperidone treated group and the difference was significant (p<0.05). Conclusion: Olanzapine has responded better on positive symptoms of schizophrenia patients than that of risperidone. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 58-60

scholarly journals COMPARATIVE STUDY OF CLINICAL VERSUS USG IN DIAGNOSIS OF EARLY TRIMESTER BLEEDING PV

2020 ◽  
pp. 60-62
Author(s):  
Narendra Nath Hait ◽  
Brahmarshi Das ◽  
Ratan Chandra Mandal ◽  
Haricharan Roy ◽  
Debarshi Jana
Keyword(s):  
Statistical Analysis ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Common Cause ◽  
Clinical Method ◽  
Medical College ◽  
Threatened Miscarriage ◽  
Obstetrics And Gynaecology ◽  
Threatened Abortion ◽  
The Difference

Background: Threatened abortion is till most common cause of early trimester bleeding PV and can be diagnosed and managed by early USG diagnosis. Materials and methods: This was a prospective observational study. Place of the study was Department of Obstetrics and Gynaecology and Department of Radiodiagnosis, Midnapore Medical College and Hospital from January 2019 to June 2020. Eighteen months. Result: When the clinical method to diagnose threatened miscarriage was compared to the sonographic method, it was evident that sonographic method was reliable than the clinical method and the difference was statistically significant. Conclusion: In case of missed miscarriage and complete miscarriage, although the percentage of discrepancy was 100%, on further statistical analysis, the discrepancy was not statistically significant. And the cause behind this was probably inadequate sampling.

scholarly journals Response of systemic PUVA in vitiligo - experience with 25 cases in Combined Military Hospital, Dhaka

2015 ◽  
Vol 10 (1) ◽  
pp. 29-33
Author(s):  
ATM Rezaul Karim ◽  
Md Abdul Latif Khan ◽  
Md Sayeed Hasan ◽  
Moyassaque Ahmed ◽  
Shirajul Islam Khan ◽  
...  
Keyword(s):  
Therapeutic Response ◽  
Previous Treatment ◽  
Armed Forces ◽  
The Body ◽  
Military Hospital ◽  
Study Group ◽  
Inclusion Criteria ◽  
Medical College ◽  
Number Of Patients ◽  
Prospective Longitudinal

Introduction: It is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. As a result, white patches appear in the skin in different parts of the body. Objective: The objective of this study is to see the efficacy of systemic PUVA in the treatment of vitiligo patient. Methods: This is an prospective longitudinal interventional study, carried out in the depigmented area was assessed according to the department of Dermatology and Venereology, Combined Military Hospital, Dhaka in between the duration of April 2010 to March 2011. Total 25 vitiligo patients based on inclusion criteria like patient with vitiligo affecting more than 5% body surface area, patient having ivory- white fluorescence on Wood’s lamp, patient who was above 15 years of age, patient who had given written consent, patient was not taken any previous treatment etc. Results: This study showed the therapeutic response of study group after 04 weeks of therapy, 05 (20%) patients responsed Fair, 15 (60%) patients responsed Poor and no responsed by 05 (20%) patients. Therapeutic response of study group after 08 weeks of therapy showed that 15 (60%) patients responsed Fair and 10 (40%) patients responsed Poor. It was observed after 12 weeks of therapy that 13 (52%) patients responsed Poor followed by 10 (40%) patients responsed Fair and 02 (08%) patients responsed well. 29 JAFMC Bangladesh. Vol 10, No 1 (June) 2014 Therapeutic response of study group after 16 weeks of therapy was 15 (60%) patients responsed Fair, followed by 06 (24%) patients responsed Poor and 04 (16%) patients responsed Good. It was showed that after 20 weeks of therapy 13 (52%) patients responsed Fair, followed by 08 (32%) patients responsed Good, 03 (12%) patients responsed Poor and 01 (04%) patients responsed Excellent. It was observed that after 24 weeks of therapy 12 (48%) patients responsed Good, followed by 08 (32%) patients responsed Fair, 03 (12%) patients responsed Poor and 02 (08%) patients responsed Excellent. Conclusion: Systemic PUVA for the repigmentation of vitiligo seems to be effective. Study needs large number of patients for longer period of duration for confirmation of results. DOI: http://dx.doi.org/10.3329/jafmc.v10i1.22900 Journal of Armed Forces Medical College Bangladesh Vol.10(1) 2014

scholarly journals SERUM ELECTROLYTE ESTIMATATION AS AN EARLY PREDICATOR FOR GRADING SEVERITY OF HEPATIC ENCEPHALOPATHY

2021 ◽  
pp. 32-35
Author(s):  
Sonu Kumar ◽  
Anuradha Singh ◽  
Prashant Kumar
Keyword(s):  
Statistical Analysis ◽  
Hepatic Encephalopathy ◽  
Serum Sodium ◽  
Inclusion Criteria ◽  
Observation Study ◽  
Exclusion Criteria ◽  
Sodium Potassium ◽  
Medical College ◽  
Spss Software

*AIMS AND OBJECTIVES:- 1) Alteration in the level of Serum Sodium,Potassium and Chloride in hepatic encephalopathy. 2) Correlation of these levels with severity of hepatic encephalopathy due to various causes. 3) The role of Serum Sodium,Potassium and Chloride as a predictor for grading of severity of hepatic encephalopathy. *STUDY-DESIGN:- Prospective observation study (a) Inclusion criteria:- All children with clinical and biochemical evidence of liver dysfunction having neuropsychiatric changes were included. (b) Exclusion criteria:- Cases with meningioencephalitis and other cases of encephalopathy will be excluded. * SETTING:- Upgraded department of Paediatrics,PMCH,Patna. *STUDY GROUP:- All children with hepatic encephalopathy, they were admitted in paediatrics ward of Patna Medical College and Hospital,Patna,during the period of Jan 2018 to Dec-2019. *PLAN FOR STATISTICAL ANALYSIS:- Statistical analysis was done by using Descriptive Statistics,Standard Deviation,Standard Error of Mean and using SPSS Software .

scholarly journals Study of Serum FT3, FT4 and TSH Levels in Pregnant Women

2016 ◽  
Vol 27 (2) ◽  
pp. 1-4 ◽  
Author(s):  
Shahanara Yeasmin ◽  
AFM Anwar Hossain ◽  
Tahmina Yeasmin ◽  
Md Ruhul Amin
Keyword(s):  
Statistical Analysis ◽  
Pregnant Women ◽  
Childbearing Age ◽  
Cross Sectional ◽  
Medical College ◽  
Control Serum ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Tsh Levels

Thyroid disease have a strong predominance in woman of childbearing age. Pregnancy may be associated with thyroid dysfunction. Our objective was to assess the serum FT3, FT4 and TSH levels in pregnant women. This cross-sectional analytical study was done in the Department of Physiology of Dhaka Medical College from July 2006- June 2007. Total 50 apparently healthy women of low socioeconomic class, age ranged from 18- 40 years were selected from the Outpatient Department of urban primary health care project at Mirpur, Dhaka. Out of them 30 pregnant women of different trimester were taken as study group and 20 age matched non pregnant women were taken as control. Serum FT3, FT4 and TSH levels were parameters in both groups. Statistical analysis was done by the SPSS 12.0 programme. The means ( SD) of serum FT3 levels were 6.36 1.16 p mol/L and 6.38 1.38 p mol/L, FT4 levels were 20.25 4.77 pmol/L and 19.39 8.17 pmol/L and TSH levels were 0.96 0.96 mIu/L and 1.27 0.86 mIu/L in group A (Study) and group B (control) respectively. The difference of means ( SD) of serum FT3 , FT4 and TSH levels were not significant (p>0.05) between group A and B. From the statistical analysis of the results obtained in the present study and their comparison with those of published reports, it may be concluded that there is no change of serum FT3, FT4 and TSH levels in pregnancy.Medicine Today 2015 Vol.27(2): 1-4

scholarly journals Oxidative Stress and Antioxidant Status in Schizophrenia Patients

2016 ◽  
Vol 12 (2) ◽  
pp. 40-43
Author(s):  
Fatema Zerin Khan ◽  
Syeda Papia Sultana ◽  
Mohammad SI Mullick ◽  
Nargis Akhter
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Antioxidant Status ◽  
Armed Forces ◽  
Control Group ◽  
Study Group ◽  
Medical College ◽  
Anti Oxidant ◽  
Endogenous Antioxidants ◽  
Medical University

Introduction: Oxidative stress has been assumed to contribute to the pathophysiology of schizophrenia. Increased oxidative stress is the result of either an increased production of free radicals or a depletion of the endogenous antioxidants. Objective: To assess the levels of oxidative stress and antioxidant status in schizophrenia. Materials and Methods: This observational study was carried out in the department of Pharmacology, Bangabandhu Sheikh Mujib Medical University from September 2013 to January 2015. Ninety three schizophrenia patients were enrolled as study group and 30 healthy indivuduals were taken as control group. The peripheral levels of several molecules associated with oxidative stress namely malondialdehyde (MDA), glutathione (GSH) and anti-oxidant status like plasma levels of ascorbic acid (vitamin C) and α-tocopherol (vitamin E) in 93 patients with schizophrenia and 30 healthy participants were assessed. Results: Study found that the schizophrenia group presented substantially higher levels of oxidative stress than the control group, as revealed by elevated quantities of the pro-oxidant MDA (6.3±0.5μmol/L in study group and 2.1±0.5μmol/L in control group), decreased levels of the antioxidants GSH (0.6±0.2mg/gm of Hb in study group and 2.1±0.5mg/gm of Hb in control group), plasma α-tocopherol and ascorbic acid. Results found were highly significant (p=0.001). Conclusion: In schizophrenia there are increased level of oxidative stress and decreased level of the antioxidants. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 40-43

scholarly journals A Comparative Study on Efficacy of Methotrexate and Sulphasalazine in Spondyloarthropathies

2011 ◽  
Vol 24 (1) ◽  
pp. 43-47
Author(s):  
NS Afsar ◽  
MMN Khan ◽  
MMH Chowdhury ◽  
SA Haq ◽  
M Khalilur Rahman ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Disease Duration ◽  
Wide Spectrum ◽  
Female Ratio ◽  
Male Female Ratio ◽  
The Mean ◽  
The Difference ◽  
Medical University ◽  
Active Disease

Background: Spondyloarthropathies include a wide spectrum of disease. The study was conducted with the aim of observing the efficacy of SSZ and MTX in different subclasses of spondyloarthropathies and to compare the treatment response of the two drugs. Methods: This study was conducted in the Department of Medicine and Rheurnatology clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU) between January 1999 and July 2001.A total number of one hundred twenty five patients was included in the study. Patients with active disease more than three months, regularly taking NSAIDs and not on DMARD in the last three months were included in the study. Monthly follow up of the patients was done for 6 months. Result: One hundred twenty five patients were included in this study. Male female ratio was 11.5:1. Mean age of patients was 24.17±7.15 years. The mean disease duration was 47.8±32.8 months. The present study categorized the patients into responder and non responder. Among the 78 patients in AS subclass, after completion of 6 month trial 55.6% patients in SSZ group and 39.4% patients in MTX group were categorized responder. The difference of response between drug groups was not significant (p=0.158). In the JCA subclass 81.82% in SSZ and 50% in MTX group were responder. The numbers of patient in Reiter's/Reactive Arthritis in our study were too small to make a definite comment. Conclusion: It can be concluded from this study that both the SSZ and MTX are effective DMARDs for spondyloarthropathies. Statistical analysis did not prove superiority of one drug over another, though the response rates were numerically higher in SSZ group. TAJ 2011; 24(1): 43-47

Effect of Αlfa-Tocopherol on Pain and Inflammation of Rats

2018 ◽  
Vol 5 (1) ◽  
pp. 15-18
Author(s):  
Tasneema Juaira ◽  
Noorzahan Begum ◽  
Md Abdullah Yusuf ◽  
Mohammad Asaduzzaman Patwary
Keyword(s):  
Normal Saline ◽  
Formalin Test ◽  
Treated Group ◽  
Test Duration ◽  
Loading Dose ◽  
Paw Edema ◽  
Group A ◽  
The Difference ◽  
Group B ◽  
Medical University

Background: Alfa-tocopherol (αT) is a naturally occurring lipid soluble anti-oxidant that protects our body from oxidative process.Objective: The purpose of the present study was to assess the effects of α-tocopherol on pain and inflammation in rats.Methodology: This prospective experimental study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh from January 2013 to December 2013. Ten (10) male Long Evans rats, weighing 180 to 250 grams, were collected from Bangladesh Institute of Research and Rehabilitation for Diabetic Endocrine and Metabolic Disorders (BIRDEM), Shahbag, Dhaka for this purpose. On the basis of vitamin, all the rats were divided into two (02) groups (5 rats in each group). Group A received normal saline and group B received α-tocopherol. All the groups received single dose and equal volume through intraperitoneal route. Just one hour after administrations, 5 rats of each group were subjected to formalin test followed by formalin induced paw edema test.Results: In early, inter and late phases, the frequencies of jerking was significantly lower in group B than that of group A. In the early and late phases of formalin test duration of flexing and licking was significantly (p<0.05) lower in group B than that of group. In this study, mean±SE of paw edema volume in group A (0.28 ± 0.02 ml) was higher than that of group B (0.20 ± 0.03) but the difference was not statistically significant (p=0.070). Supplementation with single loading dose of α-tocopherol significantly (p<0.05) lowered the variables for nociceptive pain, central analgesic activity and inflammatory pain in comparison to normal saline treated group (control). Inflammations were also non-significantly reduced than those of control rats.  Conclusion: From this study it may be concluded that, single loading dose of α-tocopherol have analgesic and anti-inflammatory effect.Journal of Current and Advance Medical Research 2018;5(1):15-18

Olfactory Functions Difference on Gas Station Workers Using Sniffin’ Sticks Test

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Irwan pernandi Sagala ◽  
Delfitri Munir ◽  
Andrina Y.M Rambe
Keyword(s):  
Statistical Analysis ◽  
Confidence Level ◽  
Chronic Exposure ◽  
Olfactory Function ◽  
Inclusion Criteria ◽  
Chi Square ◽  
Cross Sectional ◽  
Gas Station ◽  
The Difference ◽  
Operator Group

ABSTRACT Background: Chronic exposure of volatile substances can cause the impaired olfactory function. Objective: To identify the difference of olfactory function at Gas Station workers in Medan city. Method: Cross-sectional analitic study. A total of 80 persons consisting of 40 gas station operators and 40 non-operators who fulfilled the inclusion criteria. The applied statistical analysis was Mann Whitney, Fisher's Exact, Chi Square, T independent, Spearman with 95% confidence level. Result: Proportion of the impaired olfactory function in the gas station operator group by 77.5% and non-operator group by 0%. Significant correlation was obtained between age, duration of work with the impaired olfactory function (p = 0,047, p = 0,001). The gas station  operators will suffer the impaired olfactory function if they works for ≥ 3.89 years. Conclusion: There were differences of olfactory functions on the gas station workers by using Sniffin 'Sticks Test.

scholarly journals Correlation of Hand Hygiene Knowledge and Hand Decontamination Practices of Medical Students

2021 ◽  
Vol 10 (02) ◽  
pp. 147-151
Author(s):  
Syeda Ghadeer Zehra Naqvi ◽  
Nazish Jaffar ◽  
Syeda Aqeela Zehra ◽  
Rubina Ghani ◽  
Hasan Ali
Keyword(s):  
Medical Students ◽  
Public Sector ◽  
Hand Hygiene ◽  
Practical Implication ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Medical College ◽  
The Difference ◽  
Medical University

Objectives: To determine the knowledge of MBBS students of a public sector medical university regarding hand hygiene and to assess the practical implication of their knowledge regarding hand hygiene during the clinical postings. Study Design and Setting: A cross sectional study was conducted in Sindh Medical College, Jinnah Sindh Medical University (SMC-JSMU) Karachi, from July to November 2018. Methodology: A total of 316 M.B.B.S students from first year to final year were included in the study. Students were equally divided into preclinical and clinical groups. Hence, the knowledge of preclinical and clinical students were compared in the present study. Age range of participants was 18 to 24 years and both male and female participants were involved. Data was analyzed by SPSS 22.0. P value < 0.05 was considered as statistically significant. Results: Approximately 249 (78.8%) students agreed that hands of health care workers are a source of nosocomial infections. Nearly 293 (92.7%) students admitted that hand decontamination and gloving is necessary before bedside procedures. Only 61 (38.6%) students performed it routinely. Chief restricting factor in performance of hand hygiene was inadequate supply of hand hygiene resources as reported by 122 (77.2%) students. Conclusions: Majority of medical students in both preclinical and clinical groups were well aware of HH practices and its significant role in infection control. However, only a limited number of students routinely performed HH. The difference between knowledge and practice of students was mainly due to the inadequate facilities of hand washing in public sector hospitals

Comparative Study Between Clean Intermittent Self-Catheterization (Cisc) and Continuous Indwelling Catheterization (Cidc) in Relieving Acute Refractory Retention of Urine Due to Benign Enlargement of Prostate (Bep)

2020 ◽  
Vol 21 (2) ◽  
pp. 105-110
Author(s):  
Md Shawkat Alam ◽  
Sudip Das Gupta ◽  
Hadi Zia Uddin Ahmed ◽  
Md Saruar Alam ◽  
Sharif Muhammod Wasimuddin
Keyword(s):  
Comparative Study ◽  
Acute Urinary Retention ◽  
Bladder Capacity ◽  
Inclusion Criteria ◽  
College Hospital ◽  
Medical College ◽  
High Incidence ◽  
Group A ◽  
Group B ◽  
Better Than

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110

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