scholarly journals Can dietary zinc diminish the impact of necrotic enteritis on growth performance of broiler chickens by modulating the intestinal immune-system and microbiota?

2019 ◽  
Vol 98 (8) ◽  
pp. 3181-3193 ◽  
Author(s):  
C Bortoluzzi ◽  
B.S. Vieira ◽  
B Lumpkins ◽  
G.F. Mathis ◽  
W.D. King ◽  
...  
Keyword(s):  
Immune System ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Necrotic Enteritis ◽  
Dietary Zinc ◽  
Intestinal Immune System ◽  
The Impact

scholarly journals Supplementing Garlic Nanohydrogel Optimized Growth, Gastrointestinal Integrity and Economics and Ameliorated Necrotic Enteritis in Broiler Chickens Using a Clostridium perfringens Challenge Model

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2027
Author(s):  
Doaa Ibrahim ◽  
Tamer Ahmed Ismail ◽  
Eman Khalifa ◽  
Shaimaa A. Abd El-Kader ◽  
Dalia Ibrahim Mohamed ◽  
...  
Keyword(s):  
Growth Performance ◽  
Clostridium Perfringens ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Economic Benefits ◽  
Production Costs ◽  
Broiler Chicks ◽  
Necrotic Enteritis ◽  
Feed Conversion ◽  
Intestinal Lesion

Necrotic enteritis (NE) caused by Clostridium perfringens (C. perfringens) results in impaired bird growth performance and increased production costs. Nanotechnology application in the poultry industry to control NE outbreaks is still not completely clarified. Therefore, the efficacy of dietary garlic nano-hydrogel (G-NHG) on broilers growth performance, intestinal integrity, economic returns and its potency to alleviate C. perfringens levels using NE challenge model were addressed. A total of 1200 male broiler chicks (Ross 308) were assigned into six groups; four supplemented with 100, 200, 300 or 400 mg of G-NHG/kg diet and co-challenged with C. perfringens at 21, 22 and 23 d of age and two control groups fed basal diet with or without C. perfringens challenge. Over the total growing period, the 400 mg/kg G-NHG group had the most improved body weight gain and feed conversion efficiency regardless of challenge. Parallel with these results, the mRNA expression of genes encoding digestive enzymes (alpha 2A amylase (AMY2A), pancreatic lipase (PNLIP) and cholecystokinin (CCK)) and intestinal barriers (junctional adhesion molecule-2 (JAM-2), occludin and mucin-2 (Muc-2)) were increased in groups fed G-NHG at higher levels to be nearly similar to those in the unchallenged group. At 14 d post challenge, real-time PCR results revealed that inclusion of G-NHG led to a dose-dependently decrease in the C. perfringens population, thereby decreasing the birds’ intestinal lesion score and mortality rates. Using 400 mg/kg of G-NHG remarkably ameliorated the adverse effects of NE caused by C. perfringens challenge, which contributed to better growth performance of challenged birds with rational economic benefits.

scholarly journals Effects of Early Nutrition and Sanitary Conditions on Oral Tolerance and Antibody Responses in Broiler Chickens

2020 ◽  
Vol 7 (4) ◽  
pp. 148 ◽  
Author(s):  
Maarten S. Hollemans ◽  
Ger de Vries Reilingh ◽  
Sonja de Vries ◽  
Henk K. Parmentier ◽  
Aart Lammers
Keyword(s):  
Immune System ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Oral Tolerance ◽  
Feeding Strategy ◽  
Later Life ◽  
Antibody Responses ◽  
Oral Exposure ◽  
Antibody Levels ◽  
Sanitary Conditions

Greater antigenic exposure might accelerate activation and maturation of the humoral immune system. After hatch, commercial broiler chickens can have early (EN) or delayed (DN) access to nutrition, up to 72 h after hatch. The immune system of EN versus DN broilers is likely more exposed to antigens after hatch. This might contribute to activation and maturation of the immune system, but might also influence the development of oral tolerance, thereby altering later life antibody responses. We studied antibody (IgM, IgY, IgA) responses between 21 and 42 d of age in fast-growing EN and DN broilers, kept under low (LSC) or high sanitary conditions (HSC). In a first experiment (n = 51 broilers), we tested whether early oral exposure to bovine serum albumin (BSA) affected later life antibody responses towards BSA and a novel antigen—rabbit γ-globulin (RGG), under HSC. In a second experiment, a total of 480 EN and DN broilers were housed under either LSC or HSC, and we studied antibody responses against both BSA and RGG (n = 48 broilers per treatment) and growth performance. Broilers kept under LSC versus HSC, had higher antibody levels and their growth performance was severely depressed. Interactions between feeding strategy (EN versus DN) and sanitary conditions, or main effects of feeding strategy, on natural and specific antibody levels, and growth performance were not observed. Levels of IgA were elevated in EN versus DN broilers, in experiment I and in batch 2 of experiment II, but not in the other batches of experiment II. We concluded that EN versus DN contributes minimally to the regulation of antibody responses, irrespective of antigenic pressure in the rearing environment.

scholarly journals Maternal Supplementation of Food Ingredient (Prebiotic) or Food Contaminant (Mycotoxin) Influences Mucosal Immune System in Piglets

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 2115
Author(s):  
Stéphanie Ferret-Bernard ◽  
Laurence Le Normand ◽  
Véronique Romé ◽  
Cindy Le Bourgot ◽  
Julie Seeboth ◽  
...  
Keyword(s):  
Immune System ◽  
Lamina Propria ◽  
Inflammatory Responses ◽  
Intestinal Barrier ◽  
Mucosal Immune System ◽  
Food Ingredient ◽  
Intestinal Immune System ◽  
Maternal Supplementation ◽  
Antigen Presenting ◽  
The Impact

The early life period is crucial for the maturation of the intestinal barrier, its immune system, and a life-long beneficial host–microbiota interaction. The study aims to assess the impact of a beneficial dietary (short-chain fructooligosaccharides, scFOS) supplementation vs. a detrimental dietary environment (such as mycotoxin deoxynivalenol, DON) on offspring intestinal immune system developmental profiles. Sows were given scFOS-supplemented or DON-contaminated diets during the last 4 weeks of gestation, whereas force-feeding piglets with DON was performed during the first week of offspring life. Intestinal antigen-presenting cell (APC) subset frequency was analyzed by flow cytometry in the Peyer’s patches and in lamina propria and the responsiveness of intestinal explants to toll-like receptor (TLR) ligands was performed using ELISA and qRT-PCR from post-natal day (PND) 10 until PND90. Perinatal exposure with scFOS did not affect the ontogenesis of APC. While it early induced inflammatory responses in piglets, scFOS further promoted the T regulatory response after TLR activation. Sow and piglet DON contamination decreased CD16+ MHCII+ APC at PND10 in lamina propria associated with IFNγ inflammation and impairment of Treg response. Our study demonstrated that maternal prebiotic supplementation and mycotoxin contamination can modulate the mucosal immune system responsiveness of offspring through different pathways.

An Economic Analysis of the Impact of Subclinical (Mild) Necrotic Enteritis in Broiler Chickens

2010 ◽  
Vol 5 (4) ◽  
pp. e39-e40 ◽  
Author(s):  
James T. Skinner ◽  
Sharon Bauer ◽  
Virginia Young ◽  
Gail Pauling ◽  
Jeff Wilson
Keyword(s):  
Economic Analysis ◽  
Broiler Chickens ◽  
Necrotic Enteritis ◽  
The Impact

scholarly journals The Role of Arginine in Disease Prevention, Gut Microbiota Modulation, Growth Performance and the Immune System of Broiler Chicken – A Review

2020 ◽  
Vol 20 (2) ◽  
pp. 325-341
Author(s):  
Harry A. Aguzey ◽  
Zhenhua Gao ◽  
Wu Haohao ◽  
Cheng Guilan ◽  
Wu Zhengmin ◽  
...  
Keyword(s):  
Immune System ◽  
Disease Prevention ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Building Blocks ◽  
The Body ◽  
Necrotic Enteritis ◽  
Poultry Production ◽  
Growth Promoters ◽  
Immune System Modulation

AbstractThe effect of dietary arginine on disease prevention, immune system modulation, the gut micro-biota composition and growth of broiler chicken was reviewed. The main aim of poultry production is the maximization of profit at the least possible cost. This objective can mainly be achieved by ensuring that there is no interference in growth or disease outbreak and by feeding chicken with the best possible level of nutrients. With the ban on antibiotic growth promoters, attention is shifted towards other nutrition methods to prevent diseases and promote growth. More attention is therefore given to protein diets in animal nutrition due to their importance as essential part of active biological compounds in the body, assisting in the breakdown of body tissue and helping in the physiological processes of the animal. Arginine plays important function in serving as building blocks of proteins and polypeptides. It performs other roles during the regulation of important biochemical functions such as maintenance, growth, reproduction and immunity. Arginine cannot be synthesized by the body so it has to be supplemented in the diet. When arginine is supplemented above the recommended level, the gut mucosa is protected, immunosuppression is alleviated, diseases like necrotic enteritis, infectious bursal disease and coccidiosis in broiler chickens are prevented. There is an improvement in growth resulting from the increase in intestinal absorption, barrier function and microbiota composition.

scholarly journals Autolyzed Yeast (Saccharomyces cerevisiae) Supplementation Improves Performance While Modulating the Intestinal Immune-System and Microbiology of Broiler Chickens

2018 ◽  
Vol 2 ◽  
Author(s):  
Cristiano Bortoluzzi ◽  
José Guilherme Morchel Barbosa ◽  
Rafaela Pereira ◽  
Naiara Simarro Fagundes ◽  
Jaqueline Moreira Rafael ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Immune System ◽  
Broiler Chickens ◽  
Yeast Saccharomyces Cerevisiae ◽  
Intestinal Immune System
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