scholarly journals The Influence of Bioinsecticide Granules of Srikaya (A. Squamosa) and Betel Leaves (P. Beetle) Extract Extracts on Kidney Histopathology in Mice (Mus musculus)

2020 ◽  
Vol 3 (1) ◽  
pp. 17
Author(s):  
Wike Rosalini ◽  
Sri Hernawati ◽  
Dwi Wahyuni

The use of chemical insecticides in the long term and high frequency will suppress insects (mosquitoes) and vectors to be tolerant until resistant. Reports of resistance from various species of mosquitoes found in multiple countries even occur in Indonesia in Surabaya. This study aimed to analyze the effect of granules bioinsecticides on the mixture of srikaya seeds (A. squamosa) and betel leaf (P. beetle) on the histopathology of mice (M. musculus) using true-experimental (the post-test only group design). Sample taken by simple random sampling and grouped into each control group and the treatment group totaling 25 mice. Data were analyzed using simple linear regression test. The results showed an overall p-value >0.05, meaning that there was no bioinsecticide effect of a mixture of betel leaf granules (Piper beetle) and srikaya seeds (Annona squamosa) on the histopathology of the kidney of mice (Mus musculus). Required safety testing of target animals in addition to mice and a preliminary examination is needed before the research is conducted so that the results are valid Keywords: bioinsecticide; histopatology; Mus musculus

2021 ◽  
Vol p6 (1) ◽  
pp. 3179-3185
Author(s):  
Roopa M.R ◽  
Vasudev A Chate ◽  
Shreevathsa Shreevathsa ◽  
Mohan Kumar G

Introduction: Shwasa is said as Shigrapranahara Roga. It occurs as the main disease and also a symptom in various diseases. Shwasakruchrata is a common symptom that occurs in Hrudroga. Acharya Charaka mentioned the unique classification of drugs based on their action. Shwasahara Dashemani is one among them. It is containing 10 herbal drugs which are specially indicated in Shwasa Roga. Hence to evaluate the efficacy of Shwasahara Dashemani in Lakshana Roopi Shwasa in L.V.F (Cardiac Asthma) has taken for the study. Aim and Objective: The objective is to assess the efficacy of Shwasahara Dashemani in L.V.F with dyspnea (Cardiac Asthma). Method: The present study is a controlled comparative, open-label, clinical trial with pre and post-test design. A total of 40 subjects of a diagnosed case of L.V.F with dyspnea (Cardiac Asthma) were selected by using a simple random sampling method. Control group subjects were intervened with standard treatment of L.V.F and intervention group subjects were intervened with standard treatment of L.V.F along with Shwasahara Dashemani Ghana Vati, for the duration of 30 days. Its efficacy was assessed before treatment (0th day) and after treatment (31st day) by using BDI (Baseline Dyspnea Index Scale). Results: The P-value of dyspnea of the control group is 1.000 and the P-value of dyspnea of the intervention group is 0.105. This shows that the results of both groups are statistically not significant. But as compared to the control group, the intervention group is clinically significant because after the intervention 35% of subjects had shown improvement in the intervention group. Conclusion: As compared to the control group, in the intervention group Shwasahara Dashemani Ghanavati is clinically significant in relieving cardiac asthma when used with standard treatment of L.V.F. Keyword: Shwasahara Dashemani. Cardiac Asthma, L.V.F, Dyspnea


2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Okky Irtanto ◽  
Alex Pangkahila ◽  
IGM Aman

Abstract: Overtraining accelerates aging due to the excessive production of free radicals that can cause oxidative stress. Banana floret extract contains bioactive compounds with antioxidant capacity which can increase the body's defence to deal with the oxidative stress by increasing the level of superoxide dismutase (SOD). This study was aimed to prove that the banana (Musa x paradisiaca) floret extract could prevent the decrease of superoxide dismutase (SOD) levels in overtraining-induced mice (Mus musculus) BALB/c liver. This was a true experimental study with the post-test only control group design. Subjects were 36 male mice (Mus musculus), BALB/c strain, 12 weeks old, weighing 20-22 g, which were divided into two groups with 18 mice each. The control group (P0) was treated with a placebo of 1 ml aquadest and overtrained for 14 days meanwhile the treatment group (P1) was treated with banana (Musa x paradisiaca) floret extract of 400 mg/kgBW/day and overtrained for 14 days. The results showed that after 14-day treatment, the mean SOD level in the liver tissue of the P0 group was 568.82±9.558 U/mg protein whereas in the P1 group was 588.37±10.629 U/mg protein (P < 0.01). The t-independent test showed a t value of -5.804 and a P value of 0.000 which indicated that after treatment, the levels of SOD in liver tissue of both groups were significantly different. Conclusion: Banana (Musa x paradisiaca) floret extract could prevent the decrease of superoxide dismutase (SOD) levels in the liver tissue of overtraining-induced mice (Mus musculus) BALB/c.Keywords: banana floret, SOD, liver, overtrainingAbstrak: Aktivitas fisik berlebih mempercepat penuaan karena meningkatkan produksi radikal bebas yang dapat menyebabkan stres oksidatif. Ekstrak floret pisang mengandung senyawa bioaktif dengan kapasitas antioksidan yang dapat meningkatkan pertahanan tubuh dalam menghadapi stres oksidatif melalui peningkatan kadar superoksida dismutase (SOD). Penelitian ini bertujuan untuk membuktikan bahwa pemberian ekstrak floret pisang raja (Musa x paradisiaca) dapat mencegah penurunan kadar SOD pada hati mencit (Mus musculus) BALB/c dengan aktivitas fisik berlebih. Jenis penelitian ialah eksperimental murni dengan post test only control group design. Subjek penelitian ialah 36 ekor mencit (Mus Musculus) BALB/c, jantan, berumur 12 minggu, berat badan 20-22 gr, yang dibagi menjadi dua kelompok masing-masing berjumlah 18 ekor mencit. Kelompok kontrol (P0) diberikan plasebo berupa aquadest sebanyak 1 ml dengan aktivitas fisik berlebih selama 14 hari, dan kelompok perlakuan (P1) diberikan ekstrak floret pisang raja (Musa x paradisiaca) dosis 400 mg/kgBB mencit per hari dicampur aquadest hingga 1 ml dengan aktivitas fisik berlebih selama 14 hari. Hasil penelitian menunjukkan rerata kadar SOD jaringan hati pada kelompok kontrol (P0) sesudah perlakuan (post-test) ialah 568,82±9,558 U/mg protein, sedangkan pada kelompok perlakuan (P1) ialah 588,37± 10,629 U/mg protein. Analisis kemaknaan dengan T-Independent mendapatkan nilai t= -5,804 dan nilai P = 0,000 yang menunjukkan bahwa sesudah perlakuan (post-test), kadar SOD jaringan hati pada kedua kelompok berbeda sangat bermakna. Simpulan: Ekstrak floret pisang raja (Musa x paradisiaca) dapat mencegah penurunan kadar SOD pada hati mencit (Mus musculus) BALB/c dengan aktivitas fisik berlebih.Kata kunci: floret pisang raja, SOD, hati, aktivitas fisik berlebih


2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Fauziah Fauziah ◽  
Sri Lestari

Masa remaja akan diwarnai dengan perubahan fisik salah satunya adalah payudara   membesar.  Payudara   ini   memiliki   kemungkinan   akan   timbulnya penyakit salah satunya adalah kanker payudara. Namun kurangnya minat remaja dalam  mencari  informasi  mengenai  deteksi  dini  kanker payudara,  menjadikan remaja tidak paham akan penyakit kanker payudara. Tujuan penelitian ini adalah untuk mengetahui pengaruh pendidikan kesehatan melalui peer group terhadap pengetahuan dan sikap remaja putri tentang SADARI. Jenis penelitian ini menggunakan desain quasi experiment dengan pendekatan pre and post test without control group. Dengan jumlah populasi 1028 remaja putri, sehingga jumlah sampel didapatkan sebanyak 91 responden. Teknik pengambilan sampel yang digunakan dalam penelitian ini menggunakan simple random sampling. Data diperoleh dengan cara wawancara, alat pengumpulan data menggunakan kuesioner dan dianalisis secara statistik menggunakan uji Wilcoxon Signed Rank Test. Hasil pengujian hipotesis menggunakan uji Wilcoxon signed ranktest diperoleh   nilai   probabilitas  (p-value)  sebesar 0,000  (p<   0,05)   sehingga kesimpulan uji adalah terdapat pengaruh pendidikan kesehatan melalui peer group terhadap pengetahuan dan sikap remaja putri tentang SADARI.Kata kunci : Pengetahuan, Sikap, Peer Group, Remaja   ABSTRACT Adolescence will be colored by physical changes, one of which is enlarged breasts. This breast has the possibility of disease, one of which is breast cancer. But the lack of interest in adolescents in seeking information about early detection of breast cancer, makes teenagers do not understand breast cancer.The purpose of this study was to determine the effect of health education through peer groups on the knowledge and attitudes of young women about their awareness. This type of research uses a quasi experiment design with a pre and post test without control group approach. With a population of 1028 young women, so the number of samples was 91 respondents. The sampling technique used in this study used simple random sampling. Data obtained by interview, data collection tools using questionnaires and statistically analyzed using the Wilcoxon Signed Rank Test. The results of hypothesis testing using the Wilcoxon signed ranktest test obtained a probability value (p-value) of 0,000 (p <0.05) so that the conclusion of the test was that there was an effect of health education through peer groups on the knowledge and attitudes of young women.Keywords : Knowledge, Attitude,Peer Group, Adoloscence


2020 ◽  
Vol 16 (1) ◽  
pp. 55-66
Author(s):  
Yeni Nur Rahmayanti ◽  
Suhartono Suhartono ◽  
Bambang Edy Warsito

Kepuasan perawat ini sangat dipengaruhi oleh kepemimpinan dari kepala ruang. Kepemimpinan efektif yang digunakan oleh kepala ruang untuk memimpin bawahannya. Tujuan dari penelitian ini adalah untuk pengetahui pengaruh pelatihan kepemimpinan efektif kepala ruang terhadap kepuasan perawat di ruang rawat inap RSUD Karanganyar. Rancangan penelitian yang digunakan kuantitatif, bersifat quasi experimental dengan bentuk pre-post test with control group. Jumlah sampel sebanyak 18 responden pada kelompok intervensi dan 18 responden pada kelompok kontrol yang diambil dengan teknik simple random sampling. Hasil analisis menunjukkan adanya perbedaan kepuasan perawat antara sebelum dan setelah dilakukan pelatihan kepemimpinan efektif kepala ruang (p value = 0,000). Penelitian ini menyimpulkan adanya pengaruh kepemimpinan efektif terhadap kepuasan perawat.


2020 ◽  
Vol 5 (1) ◽  
pp. 9-17
Author(s):  
Try Putra Parmana ◽  
Edison Siringoringo ◽  
Safruddin

Abstrak Hipertensi merupakan penyakit yang dapat menyebabkan kecacatan permanen dan kematian secara mendadak akibat penyakit ikutannya seperti stroke, gagal ginjal dan lainnya. Berdasarkan dari dokumentasi buku laporan kesehatan 10 penyakit terbanyak pada satu tahun terakhir di pustu Benjala menunjukkan kasus hipertensi menjadi urutan pertama. Pengukuran time series dalam 3 bulan terakhir yaitu pada bulan November 2017 sampai bulan januari 2018 penderita hipertensi . penelitian ini adalah untuk mengetahui dan mengidentifikasi Pengaruh Rendam Kaki dengan Air Hangat terhadap Tekanan Darah Pasien Hipertensi Diwilayah Kerja Pustu Kelurahan Benjala Tahun . Penelitian ini menggunakan desain penelitian  True-Eksperimen dengan rancangan penelitian Pre and post test control group design.. Sampel penelitian ini sebanyak 34 responden kelompok eksperimen yang diambil dengan metode simple random sampling. Kelompok eksperimen  mendapatkan terapi rendam kaki dengan air hangat selama 5 kali perlakuan dengan durasi 15 menit . Analisis data dalam penelitian ini menggunakan uji statistik uji Wilcoxon.Hasil analisis menggunakan uji statistik wilcoxon dengan tingkat kepercayaan (α = 0,05). Berdasarkan hasil uji wilcoxon menunjukkan bahwa ada penurunan rerata tekanan darah sistolik dan diastolik sebelum dan setelah dengan nilai p-Value = < 0,05. Maka Ha diterima dan Ho ditolak.  Kesimpulan : dari penelitian  ini adalah terdapat pengaruh  rendam kaki dengan air hangat terhadap tekanan darah pasien hipertensi di wilayah kerja pustu kelurahan benjalaPeneliti menyarankan agar hasil penelitian ini bisa dijadikan sebagai referensi untuk pengaplikasian dalam ruang lingkup pelayanan keperawatan khususnya dalam menangani  hipertensi. Kata Kunci : Rendam Air Hangat, Pasien Hipertensi


2019 ◽  
Vol 3 (2) ◽  
pp. 78-85
Author(s):  
Rahmawati Dian Nurani ◽  
Erna Rochmawati ◽  
Nurchayati Nurchayati

Hemodialisis merupakan salah satu terapi untuk pelaksanaan penyakit ginjal kronis tahap akhir. Pasien yang menjalani hemodialisis sering mengalami komplikasi seperti gangguan tidur. Salah satu cara untuk meningkatkan kualitas tidur yaitu terapi murottal. Tujuan penelitian untuk mengetahui efektifitas terapi murottal Al Qur’an terhadap kualitas tidur. Penelitian ini merupakan quasy-experiment dengan pre-test and post-test with control group design. Sampel penelitian adalah 38 orang dengan teknik simple random sampling. Analisis yang digunakan independent sample t test. Hasil penelitian menunjukkan peningkatan kualitas tidur dengan p-value = 0,000 (p < 0,05). Terdapat efektifitas murottal Al Qur’an dalam meningkatkan kualitas tidur pasien hemodialisa.


Author(s):  
Yanti Nopita ◽  
Susmiati Susmiati ◽  
Emil Huraini

Hemodialysis is a kidney replacement therapy for clients with chronic renal failure. Hemodialysis therapy helps the client's survival, but on the other hand the client will experience various problems including psychosocial problems, which ultimately affect the client's quality of life. Self Help Group is a social support therapy and the Mobile Messaging Apps (WhatsApp) application can be used in Self Help Group. The purpose of this study was to determine the effect of implementing a combination of Self Help Group and the use of Mobile Messaging Apps on the quality of life of clients with chronic kidney failure. The research design was quasy experiment with pre and post test design with control group, the sampling technique was simple random sampling. The research sample consisted of 42 people, consisting of 21 respondents in the control group and 21 in the intervention group. The test results showed the effect of implementing a combination of Self Help Group and the use of Mobile Messaging Apps on the quality of life of clients with p value < 0.05. It is recommended that Self Help Group and the use of WhatsApp be implemented as part of nursing interventions in nursing care. Keywords: mobile messaging apps; quality of life; self help group ABSTRAK Hemodialisa merupakan salah satu terapi pengganti ginjal bagi klien gagal ginjal kronik. Terapi hemodialisa membantu kelangsungan hidup klien, namun di sisi lain klien akan mengalami berbagai masalah termasuk masalah psikososial, yang pada akhirnya mempengaruhi kualitas hidup klien. Self Help Group adalah salah satu terapi dukungan sosial dan aplikasi Mobile Messaging Apps (WhatsApp) aplikasi yang dapat digunakan dalam Self Help Group. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penerapan kombinasi Self Help Group dan penggunaan Mobile Messaging Apps terhadap kualitas hidup klien gagal ginjal kronik. Desain penelitian yang digunakan yaitu quasy experiment dengan rancangan pre and post test with control group, teknik pengambilan sampel yaitu simple random sampling. Sampel penelitian berjumlah 42 orang terdiri dari 21 responden kelompok kontrol dan 21 kelompok intervensi. Hasil uji menunjukkan adanya pengaruh penerapan kombinasi Self Help Group dan penggunaan Mobile Messaging Apps terhadap kualitas hidup klien dengan p value < 0,05. Direkomendasikan Self Help Group dan penggunaan WhatsApp diterapkan sebagai bagian intervensi keperawatan dalam asuhan keperawatan. Kata kunci: mobile messaging apps; kualitas hidup; self help group


2017 ◽  
Vol 1 (1) ◽  
pp. 26
Author(s):  
Dwi Heppy Rahcmawati ◽  
Betie Febriana

AbstrakProses hidup lansia telah menghadapi berbagai masalah yang dapat mempengaruhi perkembangan psikologi lansia. Studi terdahulu menemukan bahwa konsep diri dan makna hidup merupakan hal yang paling terpengaruh pada usia lanjut. Jika tidak diatasi, hal ini akan memicu depresi pada lansia. Oleh karena itu, dibutuhkan terapi untuk meningkatkan konsep diri dan kemampuan memaknai hidup lansia. Penelitian ini bertujuan melihat efektifitas logoterapi terhadap peningkatan konsep diri dan kemampuan memaknai hidup lansia di panti. Desain pada penelitian ini adalah kuantitatif dengan Quasi Experimental Pre-Post Test Without Control Group Design. Jumlah sampel sebanyak 30 responden dengan teknik simple random sampling. Hasil penelitian ini menunjukkan bahwa perbedaan secara bermakna pada konsep diri (nilai p= 0,000) dan makna hidup (nilai p=0,000) lansia sebelum dan sesudah terapi. Logoterapi merupakan salah satu intervensi yang dapat digunakan pada lansia atau masalah psikososial. Pemberian logoterapi pada lansia berdampak pada peningkatan harga diri lansia dari rendah ke tinggi yaitu sebesar 22 responden artinya73% terjadi peningkatan harga diri-konsep diri dan ini merupakan angka yang cukup tinggi dan bermakna. Kesimpulan logoterapi efektif untuk meningkatkan konsep diri dan makna hidup lansia di Panti Pelayanan lansia di Panti pelayanan sosial pucang gading Semarang. Kata kunci: konsep diri, makna hidup, logoterapi, lansia AbstractThe effectiveness of logotherapy on improving self-concept and the ability to interpret the life of the elderly. The life process of the elderly has faced various problems that can affect the psychological development of the elderly. Previous studies have found that self-concept and the meaning of life are the most affected in old age. If not overcome, this will trigger depression in the elderly. Therefore, therapy is needed to improve self-concept and the ability to interpret the life of the elderly. This study aims to see the effectiveness of logotherapy on improving self-concept and the ability to interpret the life of the elderly in the institution. The design in this study is quantitative with Quasi Experimental Pre-Post Test Without Control Group Design. The number of samples was 30 respondents with simple random sampling technique. The results of this study indicate that there are significant differences in self-concept (p value = 0,000) and the meaning of life (p value = 0,000) the elderly before and after therapy. Logotherapy is one intervention that can be used in the elderly or psychosocial problems. The provision of logotherapy in the elderly has an impact on increasing the self-esteem of the elderly from low to high, which is 22 respondents, meaning that 73% of the increase in the price of self-concept is self and this is a fairly high and meaningful number. Conclusion Effective logotherapy to improve self-concept and the meaning of elderly life in Panti Elderly services at the social service center of Semarang ivory. Keywords: self-concept, meaning of life, logotherapy, elderly


2021 ◽  
Vol 21 (1) ◽  
pp. 103
Author(s):  
Nurul Atika Zar’ah ◽  
Syachruddin Syachruddin ◽  
Kusmiyati Kusmiyati

Green betel leaf (Piper betle L.) contains secondary metabolites, namely alkaloids, flavonoids, steroids, terpenoids, saponins, tannins. Green betel leaf (Piper betle L.) is widely used for wound healing, especially in rural Indonesians. This study aims to determine the effect of green betel leaves extract (Piper betle L.) on wound healing in mice (Mus musculus L.). The samples were determined using a randomized block design (RBD) using mice (Mus musculus L.) which consisted of three treatment groups using a concentration of 20%, 30%, 40% and one control group. The Measure of the average diameter of the wound was using a ruler on each side of the diameter. The data measurement for the average diameter of wound restriction was analyzed by using the one way. The one way Anova test showed that the sig or p-value is 0.000 <0.05 (at the alpha level of 5%) so that Ho is rejected which indicates that there is an effect of giving green betel leaf extract (Piper betel L.) on wound healing in mice (Mus musculus L.). Based on the results of the LSD or LSD test, it shows that it is not significant / the same because the sig value is 0.074> 0.05, which means that no change occurs in mice when given 30% or 40% extract. Green betel leaf extract (Piper betle L.) has an effect on wound healing in mice (Mus musculus L.).  


2020 ◽  
pp. 113-121
Author(s):  
Aris Setyawan ◽  
W Widyandana ◽  
Efrayim Suryadi ◽  
Bekti Sukoco

Kepuasan belajar mahasiswa menjadi salah satu tolok ukur keberhasilan sistem pendidikan yang diterapkan di sebuah institusi. Kepuasan belajar juga merupakan salah satu faktor yang dapat memprediksi hasil belajar. Sebagai upaya meningkatkan kepuasan belajar mahasiswa pada pembelajaran keterampilan klinik, perlu bagi institusi pendidikan untuk memberikan inovasi pembelajaran berbasis teknologi. Metode yang ditawarkan adalah Online peer-assisted learning. Tujuan dalam penelitian ini adalah untuk mengetahui perbedaan kepuasan belajar pemeriksaan fisik thorak sebelum dan setelah diterapkan metode Online peer assisted learning. Penelitian ini menggunakan desain Quasy Experimental, dengan pendekatan post-test control group design. Populasi penelitian ini adalah mahasiswa keperawatan tahun kedua  STIKes Surya Global sebanyak 140 mahasiswa. Jumlah responden 70  diambil dengan tekhnik simple random sampling menjadi kelompok kontrol dan intervensi. Kelompok intervensi diberikan model pembelajaran Peer-assisted learning (PAL) dengan bantuan teknologi video call dalam whatsapp. Kelompok kontrol dengan model pembelajaran Peer-assisted learning face to face seperti yang selama ini dilakukan. Instrumen kepuasan belajar dalam penelitian ini diadopsi dari penelitian Cohen dan Baruth. Analisis data menggunakan uji independet t  test untuk membandingkan rata-rata nilai posttest kepuasan belajar. Hasil analisis menunjukan terdapat peningkatan kepuasan belajar secara signifikan dengan nilai p value 0.001. Rerata nilai kepuasan belajar metode Online Peer Asisted Learning (OPAL 41,65 (SD = 2,85), dan nilai rerata kepuasan belajar dengan metode Peer Asisted Learning (PAL) 39,05 (SD =3,10). Metode Online peer assisted learning (OPAL) terbukti mempunyai pengaruh yang signifikan terhadap kepuasan belajar keterampilan pemeriksaan fisik thorak pada mahasiswa keperawatan.    Student learning satisfaction is one of the benchmarks for the success of the education system implemented in an institution. Learning satisfaction is also one of the factors that can predict learning outcomes. In an effort to increase student learning satisfaction in clinical skills learning, it is necessary for educational institutions to provide technology-based learning innovations. The method offered is online peer-assisted learning. The purpose of this study was to determine differences in learning satisfaction in the physical examination of Thorax before and after the online peer assisted learning method was applied. This study used a Quasy Experimental design, with a post-test control group design approach. The population of this study were 140 students of the second year of STIKes Surya Global nursing students. Respondents 70 were taken by simple random sampling technique into the control and intervention groups. The intervention group was given a Peer-assisted learning (PAL) learning model with the help of video call technology in WhatsApp. The control group uses the face-to-face peer-assisted learning model as has been done so far. The learning satisfaction instrument in this study was adopted from Cohen and Baruth's research. The data analysis used the independent t test to compare the average posttest scores for learning satisfaction. The analysis showed that there was a significant increase in learning satisfaction with a p value of 0.001. The mean value of learning satisfaction with the Online Peer Asisted Learning method (OPAL 41.65 (SD = 2.85), and the average value of learning satisfaction with the Peer Asisted Learning (PAL) method is 39.05 (SD = 3.10). Online peer assisted method Learning (OPAL) is proven to have a significant effect on the learning satisfaction of Thoracic physical examination skills in nursing students.


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