scholarly journals Insights Into the Changing Landscape of Coronavirus Disease 2019

Author(s):  
Ruby A. Escobedo ◽  
Deepak Kaushal ◽  
Dhiraj K. Singh

Coronavirus disease 2019 (COVID-19) is a highly contagious, infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in late 2019 in Wuhan China. A year after the World Health Organization declared COVID-19 a global pandemic, over 215 million confirmed cases and approximately 5 million deaths have been reported worldwide. In this multidisciplinary review, we summarize important insights for COVID-19, ranging from its origin, pathology, epidemiology, to clinical manifestations and treatment. More importantly, we also highlight the foundational connection between genetics and the development of personalized medicine and how these aspects have an impact on disease treatment and management in the dynamic landscape of this pandemic.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 748-752
Author(s):  
Swapnali Khabade ◽  
Bharat Rathi ◽  
Renu Rathi

A novel, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes severe acute respiratory syndrome and spread globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus as a COVID- 19, a global pandemic. This pandemic happened to be followed by some restrictions, and specially lockdown playing the leading role for the people to get disassociated with their personal and social schedules. And now the food is the most necessary thing to take care of. It seems the new challenge for the individual is self-isolation to maintain themselves on the health basis and fight against the pandemic situation by boosting their immunity. Food organised by proper diet may maintain the physical and mental health of the individual. Ayurveda aims to promote and preserve the health, strength and the longevity of the healthy person and to cure the disease by properly channelling with and without Ahara. In Ayurveda, diet (Ahara) is considered as one of the critical pillars of life, and Langhana plays an important role too. This article will review the relevance of dietetic approach described in Ayurveda with and without food (Asthavidhi visheshaytana & Lanhgan) during COVID-19 like a pandemic.


2021 ◽  
Vol 9 (2) ◽  
pp. 60-69
Author(s):  
Ridwan Olamilekan Adesola ◽  
Oluwatobi Emmanuel Oladele ◽  
Ahmed Oluwasegun Tajudeen ◽  
Ogundepo Oluwatobi Moses ◽  
Murali Dinesh

Coronavirus disease 2019 (COVID-19), confirmed as the global pandemic on March 11, 2020, by the World Health Organization (WHO), was caused by the outbreak of an emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first reported in Wuhan city, China, in December 2019. Based on the previous pandemic, such as severe acute respiratory syndrome (SARS) from 2002 to 2003, Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012. The scientific developments have fast-tracked our insights SARS-CoV-2 epidemiology, likewise vaccinology relevant for developing drugs for viral infections treatment. As there are not many detailed interventions and vaccines available for disease control, the pandemic COVID-19 poses countless threats to global public health, causing a great level of insecurity and unrest worldwide. To provide an inclusive overview to global health authorities and prospective readers worldwide, we detailed in this review the epidemiology and vaccinology of SARS-CoV-2 in Nigeria.


F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 570 ◽  
Author(s):  
Hector Florez ◽  
Sweta Singh

The 2019-2020 global pandemic has been caused by a disease called coronavirus disease 2019 (COVID-19). This disease has been caused by the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2). By April 30 2020, the World Health Organization reported 3,096,626 cases and 217,896 deaths, which implies an exponential growth for infection and deaths worldwide. Currently, there are various computer-based approaches that present COVID-19 data through different types of charts, which is very useful to recognise its behavior and trends. Nevertheless, such approaches do not allow for observation of any projection regarding confirmed cases and deaths, which would be useful to understand the trends of COVID-19. In this work, we have designed and developed an online dashboard that presents actual information about COVID-19. Furthermore, based on this information, we have designed a mathematical model in order to make projections about the evolution of cases and deaths worldwide and by country.


2021 ◽  
Vol 4 (1) ◽  
pp. 1-4
Author(s):  
Gift Eyareosowo Oden ◽  
Himmat Singh ◽  
Santosh Kumar Singh ◽  
Abhay Raizada ◽  
Gaurav Gupta

In December of 2019, an outbreak of a disease began at Wuhan, China and would later be named the coronavirus disease2019 (covid-19) by the World Health Organization and further declared a global pandemic. Since the onset of this disease, the pattern of day to day activities had been disrupted in a bid to curb this menace to society. This paper work touches on basic viral classification, as well as structure of the severe acute respiratory syndrome coronavirus 2, the main causative agent of covid-19. This review work also sheds light on symptoms associated with this disease, mode of transmission, method of diagnosis and medications available in treating the symptoms. Potential vaccines available in India are also discussed here.


2020 ◽  
Vol 4 (2) ◽  
pp. 58-63
Author(s):  
Hassan Waqar ◽  
Ammar Arshad ◽  
Tayyab M Shera ◽  
Asad M Raza ◽  
Hassan M ◽  
...  

Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, was declared a global pandemic by the World Health Organization in March 2020. A cluster of unexplained pneumonia cases linked to the Huanan seafood market in Wuhan, China was first reported on December 31, 2019. After testing negative for common respiratory viruses, these patients tested positive for a novel coronavirus - severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), which is the cause of coronavirus disease 2019 (COVID-19). Some of these initial patients demonstrated hypoxemia, ground glass opacification on chest imaging, abnormal laboratory results - low white blood cell (WBC) count, low absolute lymphocyte count (ALC), low platelet count, elevated liver enzymes, and elevated creatinine. COVID-19 was declared a global pandemic by the World Health Organization with over 23,697,273 confirmed cases in over 200 countries and territories as of August 26, 2020. Pakistan is among the few countries which were initially hit hard but have had a remarkable recovery, with the cases falling from 4000+ per day in March to only 400+ cases in the current month. As of August 26, 2020, 278,939 cases out of a total of 294,139 positive cases have recovered. However, according to a local study 15000 doctors and paramedics were tested for COVID 19 antibodies and 32% were found to be positive, indicating the extent to which healthcare professionals have been affected and several have lost their lives. Keywords: Covid-19 in Pakistan, SARS-Cov2, Pandemic 2020


2021 ◽  
Vol 15 (1) ◽  
pp. 62-73
Author(s):  
Vaishali Deshwal ◽  
Vimal Kumar

Background: COVID-19 is an infectious disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It has been recognized as a pandemic by the World Health Organization (WHO) on 11th March, 2020. Objective: To identify various factors that can increase coronavirus spread in India and predict COVID-19 cases up to 27th December, 2020, minimum and maximum number of deaths due to COVID-19 in India. Methods: This work predicts COVID-19 cases, the minimum and the maximum number of deaths due to COVID-19 in India based on the infection rate and suspected cases. Results: Our result shows that the number of COVID-19 cases will increase exponentially in India to approximately 859421415 cases by 27th December 2020. Conclusion: The spread of COVID-19 in India depends on a lot of factors such as religious congregation, social contact structure, low testing rates, identification of COVID-19 suspects, measures such as lockdown and sealing of hot stop, etc. taken by the Indian government. In India, lockdown proved to be a good decision.


2021 ◽  
Vol 8 (4) ◽  
pp. 01-03
Author(s):  
Ashish Gujrathi

COVID-19 is an infectious disease that originated in Hubei province of the Wuhan city in China in late December. The highly contagious disease, caused by a virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is transmitted from humans to humans. After the first case in Wuhan, the disease rapidly spread to other parts of the globe. On March 11, 2020, the World Health Organization (WHO) made an assessment that COVID-19 can be characterized as a pandemic. Thus, social-distancing became an important measure to stop the spread of this disease. Various countries across the world adopted nationwide lockdown. This led to a completely new scenario for the world, where every business in each industry faced new challenges and witnessed new opportunities.


2020 ◽  
Vol 40 (4) ◽  
pp. 273-280 ◽  
Author(s):  
Saleh A. Alqahtani ◽  
Abdulrahman A. Aljumah ◽  
Almoutaz Hashim ◽  
Thamer H. Alenazi ◽  
Mohammed AlJawad ◽  
...  

ABSTRACT In December 2019, a novel coronavirus was identified in patients in Wuhan, China. The virus, subsequently named severe acute respiratory syndrome coronavirus-2, spread worldwide and the disease (coronavirus disease 2019 or COVID-19) was declared a global pandemic by the World Health Organization in March 2020. Older adults and individuals with comorbidities have been reported as being more vulnerable to COVID-19. Patients with chronic liver disease (CLD) have compromised immune function due to cirrhosis and are more susceptible to infection. However, it is unclear if patients with CLD are more vulnerable to COVID-19 and its complications than other populations. The high number of severe cases of COVID-19 has placed an unusual burden on health systems, compromising their capacity to provide the regular care that patients with CLD require. Hence, it is incredibly crucial at this juncture to provide a set of interim recommendations on the management of patients with CLD during the current COVID-19 outbreak.


Author(s):  
Francesco Di Gennaro ◽  
Damiano Pizzol ◽  
Claudia Marotta ◽  
Mario Antunes ◽  
Vincenzo Racalbuto ◽  
...  

At the end of 2019 a novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing severe acute respiratory syndrome expanded globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus a global pandemic. We performed a narrative review to describe existing literature with regard to Corona Virus Disease 2019 (COVID-19) epidemiology, pathophysiology, diagnosis, management and future perspective. MEDLINE, EMBASE and Scopus databases were searched for relevant articles. Although only when the pandemic ends it will be possible to assess the full health, social and economic impact of this global disaster, this review represents a picture of the current state of the art. In particular, we focus on public health impact, pathophysiology and clinical manifestations, diagnosis, case management, emergency response and preparedness.


2021 ◽  
Vol 12 ◽  
Author(s):  
Guanghua Zhai ◽  
Meifen Li ◽  
Ying Wang ◽  
Jian Wu

An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, at the end of 2019. The World Health Organization named the resulting infectious disease as coronavirus disease-2019 (COVID-19). Many studies concluded that patients infected with SARS-CoV-2 have different degrees of liver disturbance. However, the relationship between the drugs used for COVID-19 treatment and liver disturbance remains controversial. It is essential to evaluate the potential liver damage caused by various drugs in order to help guide clinical practice. This review analyzed the effect of drugs on hepatic function during the treatment of COVID-19.


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