scholarly journals Spectrum of Neurological Symptoms in Glycosylphosphatidylinositol Biosynthesis Defects: Systematic Review

2022 ◽  
Vol 12 ◽  
Author(s):  
Justyna Paprocka ◽  
Michał Hutny ◽  
Jagoda Hofman ◽  
Agnieszka Tokarska ◽  
Magdalena Kłaniewska ◽  
...  
Keyword(s):  
Systematic Review ◽  
Developmental Delay ◽  
English Language ◽  
Age At Onset ◽  
Personal Communication ◽  
Neurological Symptoms ◽  
Response To Treatment ◽  
Clinical Image ◽  
Publication Type ◽  
Exclusion Criteria

Background: Mutations of genes involved in the synthesis of glycosylphosphatidylinositol and glycosylphosphatidylinositol-anchored proteins lead to rare syndromes called glycosylphosphatidylinositol-anchored proteins biosynthesis defects. Alterations of their structure and function in these disorders impair often fundamental processes in cells, resulting in severe clinical image. This study aimed to provide a systematic review of GPIBD cases reports published in English-language literature.Methods: The browsing of open-access databases (PubMed, PubMed Central. and Medline) was conducted, followed by statistical analysis of gathered information concerning neurological symptomatology. The inclusion criteria were: studies on humans, age at onset (<18 y.o.), and report of GPIBD cases with adequate data on the genetic background and symptomatology. Exclusion criteria were: publication type (manuscripts, personal communication, review articles); reports of cases of GPI biosynthesis genes mutations in terms of other disorders; reports of GPIBD cases concentrating on non-neurological symptoms; or articles concentrating solely on the genetic issues of GPI biosynthesis. Risk of bias was assessed using Joanna Brigs Institute Critical Appraisal Checklists. Data synthesis was conducted using STATISTICA 13.3.721.1 (StatSoft Polska Sp. z.o.o.). Used tests were chi-square, Fisher's exact test (for differences in phenotype), and Mann-Whitney U test (for differences in onset of developmental delay).Results: Browsing returned a total of 973 articles which, after ruling out the repetitions and assessing the inclusion and exclusion criteria, led to final inclusion of 77 articles (337 GPIBD cases) in the analysis. The main outcomes were prevalence of neurological symptoms, onset and semiology of seizures and their response to treatment, and onset of developmental delay. Based on this data a synthesis of phenotypical differences between the groups of GPIBD cases and the general GPIBD cases population was made.Discussion: A synthetical analysis of neurological components in clinical image of GPIBD patients was presented. It highlights the main features of these disorders, which might be useful in clinical practice for consideration in differential diagnosis with children presenting with early-onset seizures and developmental delay. The limitation of this review is the scarcity of the specific data in some reports, concerning the semiology and onset of two main features of GPIBD.

Infrared Thermography for the Evaluation of Inflammatory and Degenerative Joint Diseases: A Systematic Review

Cartilage ◽  
2021 ◽  
Vol 13 (2_suppl) ◽  
pp. 1790S-1801S
Author(s):  
Guglielmo Schiavon ◽  
Gianluigi Capone ◽  
Monique Frize ◽  
Stefano Zaffagnini ◽  
Christian Candrian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Disease Progression ◽  
Infrared Thermography ◽  
Rheumatic Diseases ◽  
English Language ◽  
Response To Treatment ◽  
Cochrane Library ◽  
Joint Diseases ◽  
Level Of Evidence ◽  
Post Evaluation

Objective Inflammation plays a central role in the pathophysiology of rheumatic diseases as well as in osteoarthritis. Temperature, which can be quantified using infrared thermography, provides information about the inflammatory component of joint diseases. This systematic review aims at assessing infrared thermography potential and limitations in these pathologies. Design A systematic review was performed on 3 major databases: PubMed, Cochrane library, and Web of Science, on clinical reports of any level of evidence in English language, published from 1990 to May 2021, with infrared thermography used for diagnosis of osteoarthritis and rheumatic diseases, monitoring disease progression, or response to treatment. Relevant data were extracted, collected in a database, and analyzed for the purpose of this systematic review. Results Of 718 screened articles 32 were found to be eligible for inclusion, for a total of 2094 patients. Nine studies reported the application to osteoarthritis, 21 to rheumatic diseases, 2 on both. The publication trend showed an increasing interest in the last decade. Seven studies investigated the correlation of temperature changes with osteoarthritis, 16 with rheumatic diseases, and 2 with both, whereas 2 focused on the pre-post evaluation to investigate treatment results in patients with osteoarthritis and 5 in patients with rheumatic diseases. A correlation was shown between thermal findings and disease presence and stage, as well as the clinical assessment of disease activity and response to treatment, supporting infrared thermography role in the study and management of rheumatic diseases and osteoarthritis. Conclusions The systematic literature review showed an increasing interest in this technology, with several applications in different joints affected by inflammatory and degenerative pathologies. Infrared thermography proved to be a simple, accurate, noninvasive, and radiation-free method, which could be used in addition to the currently available tools for screening, diagnosis, monitoring of disease progression, and response to medical treatment.

scholarly journals Analysis of a glide path creation necessity at the initial stages of endodontic treatment

2021 ◽  
Vol 19 (1) ◽  
pp. 39-44
Author(s):  
Z. S. Khabadze ◽  
Yu. A. Generalova
Keyword(s):  
Systematic Review ◽  
Mechanical Treatment ◽  
English Language ◽  
Endodontic Treatment ◽  
Review Of The Literature ◽  
Exclusion Criteria ◽  
Path Creation ◽  
Glide Path ◽  
Iatrogenic Complications ◽  
Number Of Publications

Aim. Article is to detail the positive and negative aspects associated with the creation of a glide path with various types of endodontic instruments.Materials and methods. During a systematic review of the literature, Russian – and English-language publications were studied in the electronic databases PubMed, Google Scholar. Articles, the content of which concerns the methods of creating a glide path, as well as possible complications were included in analysis.Results. 60 articles were reviewed during the review. After analyzing the literature according to the inclusion and exclusion criteria, the total number of publications has become 32.Conclusions. According to the studied literature, it can be said that the glide path provides a predictable behavior of rotary tools and it is a recommended condition for achieving the success of endodontic treatment at the stage of canal mechanical treatment and preventing iatrogenic complications.

Ethics of resuscitation for extremely premature infants: a systematic review of argument-based literature

2020 ◽  
pp. medethics-2020-106102
Author(s):  
Alice Cavolo ◽  
Bernadette Dierckx de Casterlé ◽  
Gunnar Naulaers ◽  
Chris Gastmans
Keyword(s):  
Systematic Review ◽  
Premature Infants ◽  
English Language ◽  
Repeated Reading ◽  
Conceptual Scheme ◽  
Best Interest ◽  
Main Concept ◽  
Exclusion Criteria ◽  
Conceptual Schemes ◽  
Best Interest Principle

ObjectiveTo present (1) the ethical concepts related to the debate on resuscitation of extremely premature infants (EPIs) as they are described in the ethical literature; and (2) the ethical arguments based on these concepts.DesignWe conducted a systematic review of the ethical literature. We selected articles based on the following predefined inclusion/exclusion criteria: (1) English language articles (2) presenting fully elaborated ethical arguments (3) on resuscitation (4) of EPIs, that is, infants born before 28 weeks of gestation.AnalysisAfter repeated reading of articles, we developed individual summaries, conceptual schemes and an overall conceptual scheme. Ethical arguments and concepts were identified and analysed.ResultsForty articles were included out of 4709 screened. Personhood, best interest, autonomy and justice were concepts grounding the various arguments. Regarding these concepts, included authors agreed that the best interest principle should guide resuscitation decisions, whereas justice seemed the least important concept. The arguments addressed two questions: Should we resuscitate EPIs? Who should decide? Included authors agreed that not all EPIs should be resuscitated but disagreed on what criteria should ground this decision. Overall, included authors agreed that both parents and physicians should contribute to the decision.ConclusionsThe included publications suggest that while the best interest is the main concept guiding resuscitation decisions, justice is the least important. The included authors also agree that both parents and physicians should be actively involved in resuscitation decisions for EPIs. However, our results suggest that parents’ decision should be over-ridden when in contrast with the EPI’s best interest.

Systematic review of the magnitude of change in prevalence and quantity of Salmonella after administration of pathogen reduction treatments on pork carcasses

2016 ◽  
Vol 17 (1) ◽  
pp. 39-59 ◽  
Author(s):  
Sarah C. Totton ◽  
Julie M. Glanville ◽  
Rungano S. Dzikamunhenga ◽  
James S. Dickson ◽  
Annette M. O'Connor
Keyword(s):  
Systematic Review ◽  
English Language ◽  
Reference Lists ◽  
Risk Of Bias ◽  
Publication Type ◽  
Effect Measure ◽  
Intervention Protocol ◽  
Summary Effect ◽  
Pathogen Reduction ◽  
Positive Effect

AbstractObjective:In this systematic review, we summarized change in Salmonella prevalence and/or quantity associated with pathogen reduction treatments (washes, sprays, steam) on pork carcasses or skin-on carcass parts in comparative designs (natural or artificial contamination).Methods:In January 2015, CAB Abstracts (1910–2015), SCI and CPCI–Science (1900–2015), Medline® and Medline® In-Process (1946–2015) (OVIDSP), Science.gov, and Safe Pork (1996–2012) were searched with no language or publication type restrictions. Reference lists of 24 review articles were checked. Two independent reviewers screened 4001 titles/abstracts and assessed 122 full-text articles for eligibility. Only English-language records were extracted.Results:Fourteen studies (5 in commercial abattoirs) were extracted and risk of bias was assessed by two reviewers independently. Risk of bias due to systematic error was moderate; a major source of bias was the potential differential recovery of Salmonella from treated carcasses due to knowledge of the intervention. The most consistently observed association was a positive effect of acid washes on categorical measures of Salmonella; however, this was based on individual results, not a summary effect measure.Conclusion:There was no strong evidence that any one intervention protocol (acid temperature, acid concentration, water temperature) was clearly superior to others for Salmonella control.

scholarly journals Further Study is Needed to Define and Measure the Use of Reflective Practice in Library and Information Science

2008 ◽  
Vol 3 (1) ◽  
pp. 53 ◽  
Author(s):  
Carol Perryman
Keyword(s):  
Systematic Review ◽  
Reflective Practice ◽  
English Language ◽  
Information Science ◽  
Lessons Learned ◽  
Library And Information Science ◽  
Free Text ◽  
Exclusion Criteria ◽  
Organizational Perspective

A review of: Grant, Maria J. “The Role of Reflection in the Library and Information Sector: A Systematic Review.” Health Information and Libraries Journal (2007) 24: 155-166. Objectives - To identify and review the literature of reflective practice in Library and Information Science (LIS) in order to understand its role, particularly with regard to health libraries. Design - Systematic review Setting - LIS English-language articles indexed in the Library and Information Science Abstracts (LISA) database and published between 1969 and 2006. Subjects - 929 citations retrieved from the LISA database. Methods - The author conducted free text searches in the LISA database for the terms ‘reflective’ or ‘reflection*’ or ‘reflexion*.’ An initial search series was conducted in 2004 in order to retrieve items published between 1969-2003, then in 2007, for articles published between 2004-2006. In all, 929 article citations were retrieved. Exclusion criteria included those articles addressing the facilitation of reflective practices in others, as well as non-English language, and materials predating 1969. After review, 55 articles met the author’s relevance standard. Citation tracking then added 10 articles to the total. From this dataset, full text articles were obtained where possible, if determined on initial scrutiny to be deserving of further examination. Thirteen articles (.013%) were ultimately selected for analysis. These articles were categorized as analytical or non-analytical, with respect to perspective (individual or organizational), and recency of events (retrospective or recent). In addition, a determination was made about whether the articles’ focus was reflection occurring on (in retrospect to) or in (during) practice. Main results - Of 13 articles, 5 were found to be non-analytical, with the other 6 being analytical. Three of the non-analytical items were the reflections of an individual, while the remaining 2 offered an organizational perspective. The non-analytical accounts were found to be mostly descriptive accounts by an individual, mostly retrospective and offering no consideration of implications for LIS practice. Analytical reflective accounts attempt to systematically appraise events from the recent past, and draw conclusions in order to improve future actions. Conclusion – A gradual increase in the use of analytical reflective practice is demonstrated over the period from 1969-2006, although insufficient examples of the practice were found in the published literature. Reflective practice is likely to be beneficial to LIS practitioners, especially when time is spent in considering the implications of lessons learned from practice.

scholarly journals 146 Effect of Heroin Use on Changes of Brain Functions as Measured by fMRI, a Systematic Review

CNS Spectrums ◽  
2018 ◽  
Vol 23 (1) ◽  
pp. 91-91
Author(s):  
Jungjin Kim ◽  
Ayman Fareed ◽  
Bethany Ketchen ◽  
Woo Jin Kwak ◽  
Danzhao Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Decision Making ◽  
English Language ◽  
Functional Neuroimaging ◽  
Response To Treatment ◽  
Inclusion Criteria ◽  
Medical Subject Headings ◽  
Heroin Use ◽  
Brain Functions ◽  
Heroin Use Disorder

AbstractIn this study the authors focus on reviewing imaging studies that used resting state functional magnetic resonance imaging for individuals with a history of heroin use. This review study compiled existing research addressing the effect of heroin use on decision making by reviewing available functional neuroimaging data. Systematic review ofthe literatures using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Eligible articles were retrieved through a computer-based MEDLINE and PsycINFO search from 1960 to December 2015 using the major medical subject headings “heroin, fMRI” (all fields). Only English language was included. Thirty-seven articles were initially included in the review. Sixteen were excluded because they did not meet the inclusion criteria. The results of 21 articles that met all the inclusion criteria were presented. Based on the 21 studies included in the current review, there is evidence that heroin use may have a direct and damaging effect on certain brain functions and that these changes may be associated with impulsive and unhealthy decision making. From the review of these studies, the authors understand that a longer duration of heroinuse may be associated with more damaging effects on brain functions. The authors also understand that these brain changes could last long after abstinence, which may increase the risk of relapse to heroin use. More research is needed to create a biomarker map for patients with heroin use disorder that can be used to guide and assess response to treatment.Funding AcknowledgementsNo funding.

scholarly journals One-Minute Preceptor (OMP) applied teaching method

2021 ◽  
Vol 8 (3) ◽  
pp. 51-59
Author(s):  
Reihaneh Shagholi ◽  
Zahra Naimie ◽  
Chin Hai Leng ◽  
Rana Ahmed Abuzaid
Keyword(s):  
Systematic Review ◽  
Teaching And Learning ◽  
English Language ◽  
Web Of Science ◽  
Teaching Method ◽  
Learning Activities ◽  
Traditional Model ◽  
Search Term ◽  
Exclusion Criteria

This systematic review was conducted by searching English language articles on one-minute preceptor one-minute preceptor (OMP) through five databases, including Web of Science, ProQuest, Scopus, Clinical Key and PubMed for the published articles from 2000 to 2017 using the following search term ‘OMP’ in titles and abstracts. After employing the exclusion criteria, 31 articles remained for detailed analysis. The main outcomes of the investigated studies were categorised into two main categories, namely: (1) OMP and develop effectiveness and (2) OMP and Traditional Model & SNAPPS. The OMP is simple to remember, easy to learn, learner-centred, improve behaviour and quality of feedback, engage more in getting commitments and apply prompts the concepts and learner’s knowledge and satisfaction of learner, and an effective and efficient teaching method. The OMP developed teaching and learning activities, to convert teaching into a conversation, with the thinking work being undertaken by the learner. Keywords: One-minute preceptor (OMP), systematic review, teaching method, applied, English language  

scholarly journals Systematic review of prehospital haemostatic dressings

2019 ◽  
Vol 166 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Matthew Welch ◽  
J Barratt ◽  
A Peters ◽  
C Wright
Keyword(s):  
Systematic Review ◽  
Animal Studies ◽  
English Language ◽  
Literature Search ◽  
Clinical Evidence ◽  
Grey Literature ◽  
High Quality ◽  
Exclusion Criteria ◽  
Military Forces ◽  
Language Studies

IntroductionHaemorrhage is one of the leading causes of battlefield and prehospital death. Haemostatic dressings are an effective method of limiting the extent of bleeding and are used by military forces extensively. A systematic review was conducted with the aim of collating the evidence on current haemostatic products and to assess whether one product was more effective than others.MethodsA systematic search and assessment of the literature was conducted using 13 health research databases including MEDLINE and CINAHL, and a grey literature search. Two assessors independently screened the studies for eligibility and quality. English language studies using current-generation haemostatic dressings were included. Surgical studies, studies that did not include survival, initial haemostasis or rebleeding and those investigating products without prehospital potential were excluded.Results232 studies were initially found and, after applying exclusion criteria, 42 were included in the review. These studies included 31 animal studies and 11 clinical studies. The outcomes assessed were subject survival, initial haemostasis and rebleeding. A number of products were shown to be effective in stopping haemorrhage, with Celox, QuikClot Combat Gauze and HemCon being the most commonly used, and with no demonstrable difference in effectiveness.ConclusionsThere was a lack of high-quality clinical evidence with the majority of studies being conducted using a swine haemorrhage model. Iterations of three haemostatic dressings, Celox, HemCon and QuikClot, dominated the studies, probably because of their use by international military forces and all were shown to be effective in the arrest of haemorrhage.

scholarly journals Opioid Antagonist in the Treatment of Ischemic Stroke

2021 ◽  
Vol 11 (6) ◽  
pp. 805
Author(s):  
Juan Fernando Ortiz ◽  
Claudio Cruz ◽  
Amrapali Patel ◽  
Mahika Khurana ◽  
Ahmed Eissa-Garcés ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Ischemic Stroke ◽  
English Language ◽  
Opioid Antagonist ◽  
Stroke Patients ◽  
Exclusion Criteria ◽  
Novel Treatments ◽  
The Relationship

Stroke is a leading cause of death and disability, and novel treatments need to be found, particularly drugs with neuroprotective and restorative effects. Lately, there has been an increased interest in the relationship between opioids and ischemic stroke. To further appreciate this association between opioids and stroke, we conducted a systematic review to investigate anti-opioid medication’s effectiveness in treating ischemic stroke. We used PubMed advanced-strategy and Google Scholar searches and only included full-text clinical trials on humans and written in the English language. After applying the inclusion/exclusion criteria, seven clinical trials were reviewed. Only one of the naloxone and nalmefene clinical trials showed statistically favorable results. Overall, the nalmefene clinical trials used more updated measures (NIHSS, GOS) to evaluate recovery and functional status in ischemic stroke patients than the naloxone clinical trials. There was less bias in the nalmefene clinical trials. Animal and in vitro studies have showed promising results. Additional research should be conducted with new clinical trials of both drugs with larger samples in patients less than 70 years old and moderate to severe infarcts.

Chasing the Anchor: A Systematic Review and Meta-analysis of Perceptual Anchoring Deficits in Developmental Dyslexia

2020 ◽  
Author(s):  
Kurt D Shulver ◽  
Nicholas A Badcock
Keyword(s):  
Systematic Review ◽  
Reading Ability ◽  
English Language ◽  
Prediction Interval ◽  
Meta Analysis ◽  
Visual Assessment ◽  
Individual Performance ◽  
Future Research ◽  
Significant Heterogeneity ◽  
Eligibility Criteria

We report the results of a systematic review and meta-analysis investigating the relationship between perceptual anchoring and dyslexia. Our goal was to assess the direction and degree of effect between perceptual anchoring and reading ability in typical and atypical (dyslexic) readers. We performed a literature search of experiments explicitly assessing perceptual anchoring and reading ability using PsycInfo (Ovid, 1860 to 2020), MEDLINE (Ovid, 1860 to 2019), EMBASE (Ovid, 1883 to 2019), and PubMed for all available years up to June (2020). Our eligibility criteria consisted of English-language articles and, at minimum, one experimental group identified as dyslexic - either by reading assessment at the time, or by previous diagnosis. We assessed for risk of bias using an adapted version of the Newcastle-Ottawa scale. Six studies were included in this review, but only five (n = 280 participants) were included in the meta-analysis (we were unable to access the necessary data for one study).The overall effect was negative, large and statistically significant; g = -0.87, 95% CI [-1.47, 0.27]: a negative effect size indicating less perceptual anchoring in dyslexic versus non-dyslexic groups. Visual assessment of funnel plot and Egger’s test suggest minimal bias but with significant heterogeneity; Q (4) = 9.70, PI (prediction interval) [-2.32, -0.58]. The primary limitation of the current review is the small number of included studies. We discuss methodological limitations, such as limited power, and how future research may redress these concerns. The variability of effect sizes appears consistent with the inherent variability within subtypes of dyslexia. This level of dispersion seems indicative of the how we define cut-off thresholds between typical reading and dyslexia populations, but also the methodological tools we use to investigate individual performance.

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