scholarly journals Effects of Parenteral Supplementation with Minerals and Vitamins on Oxidative Stress and Humoral Immune Response of Weaning Calves

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1298
Author(s):  
Guillermo Alberto Mattioli ◽  
Diana Esther Rosa ◽  
Esteban Turic ◽  
Sebastián Julio Picco ◽  
Santiago José Raggio ◽  
...  

We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 kg body weight) from a selenium-deficient area of extensive cattle production on natural grass were randomly assigned to two groups (n = 20 each). One group received subcutaneous supplementation with copper, zinc, selenium, manganese and vitamins A and E (SG), and the other was given sterile saline solution (CG). The animals were supplemented twice, seven days before weaning (day −7) and on the day of weaning (day 0), and they were evaluated 30 (+30) and 60 (+60) days after weaning. Total antioxidant status (TAS), selenium-dependent glutathione peroxidase (GPx) activity, body weight, and average daily gain (ADG) were evaluated. Additionally, antibody titers were assessed prior to and after each immunization with a vaccine containing bovine herpes virus type 1 (BoHV-1). On day +30, body weight (p = 0.03) was higher in SG, whereas TAS (p = 0.02) and GPx (p = 0.0038) activity were lower in CG and remained constant in SG. Antibody titers increased in SG and CG following immunization, being higher in SG on days +30 and +60 (p < 0.05). In conclusion, parenteral supplementation of minerals and vitamins with antioxidant effects in a low-stress weaning system prevented the decrease in TAS and GPx activity, improved antibody response and had positive effects on body weight.

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 219-219
Author(s):  
Raul M Lizarraga ◽  
Esteban Galarza ◽  
Guillermo Mattioli ◽  
Anthony J Parker ◽  
Alejandro E Relling

Abstract The aim of this study was to evaluate the effect of weaning preconditioning and parenteral supplementation of minerals and vitamin on growth and plasma total antioxidant status (TAS), glucose, NEFA, and insulin concentrations, in calves at feedlot arrival. Sixty male Angus-cross calves were randomly assigned to 4 treatments (n=15/treatment). Treatments were arranged in a 2x2 factorial design; the main factors were mineral and vitamins supplementation (supplementation (S) vs no supplementation (NS)), and preconditioning (preconditioning (P) vs. not (NP)). Supplementation was applied subcutaneously on d -45, -26 and 0 and provided Cu, Mn, Se, Zn, and vitamins A and E (Adaptador Min-Vit ®, Biogénesis Bagó). Preconditioning consisted in a 26-day period between weaning and transportation at feedlot (d0) with the animals remaining in the same location. Blood samples were collected on d -26, 0 and 15. Animals were weighted on d-45, -26, 0, 8, 15 and 29. On d0 calves were load into a truck and drove for 5-hours to the feedlot. Data were analyzed using a mixed model as a 2x2 factorial, using repeated measurements. Body weight was greater on d 0, 8 15 and 29 group on groups NP, followed by S-P, and the lowest for NS-P (Triple interaction P &lt; 0.01). Treatment did not affect (P ˃ 0.1) plasma insulin and glucose concentrations. There was a triple interaction (P &lt; 0.08) for plasma TAS and NEFA concentration. Plasma TAS concentration was grater due to a decrease in its concentration for the S-P and NS-NP from d0 to d8, but not in the other treatments. Plasma NEFA concentration had the greater increase in the NP groups followed by S-NP on d0. In conclusion, 26-days precondition weaning decrease body weight compare with a traditional weaning. Mineral and vitamin supplementation in precondition weaning partially reduced that effect


Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 218
Author(s):  
Yousef Abbaslou ◽  
Davood Zahmatkesh ◽  
Ehsan Mahjoubi ◽  
Mehdi Hossein Yazdi ◽  
Hamed Beiranvand ◽  
...  

The positive effects of nucleotide (NU) supplementation in milk replacer have been elucidated in infants and in dairy calves; however, NU addition to whole milk has not been evaluated previously. This study aimed to assess NU supplementation in the whole milk on calf growth and health. Thirty Holstein calves (body weight: 39.1 ± 1.0 kg; 3 d after birth) were randomly assigned to the following treatments: whole milk without any supplementation (NU0), whole milk + 0.5 g/d added a NU-containing supplement to whole milk (NUCS0.5), and whole milk + 1 g/d added a NU-containing supplement to whole milk (NUCS1). Calves were weaned at d 55 and stayed on study until d 75. Calves had free access to feed and water throughout the study. Dry matter intakes (DMI) were similar among treatments (p > 0.05) during the pre-weaning period; however, increasing NU resulted in a linear (p < 0.05) increase in DMI during the post weaning period (2158, 2432, and 2518 g/d for NU0, NUCS0.5, and NUCS1, respectively). Treatments did not affect body weight (BW) at the first and second month of study, but final BW linearly increased as NU was added (87.1, 90.6, and 95.4 kg for NU0, NUCS0.5, and NUCS1, respectively). Neither pre-weaning average daily gain nor post-weaning average daily gain was affected by treatments; accordingly, feed efficiency was similar among treatment groups. Days with loose fecal score were linearly decreased as NU was added to whole milk during the first month of life, while the fecal score did not differ among treatments until the end of the study. No difference was observed in the skeletal growth of calves in the current study. Therefore, it can be concluded that NU supplementation in the whole milk has some beneficial effects on calf performance in terms of final BW, post-weaning DMI, and less days with loose feces.


Author(s):  
Amr M.A. Elmasry ◽  
Luis A. Miranda ◽  
Germán Mendoza ◽  
Fernando X. Plata

Background: The effects of the probiotics vary with the doses and strains used for this reason, a study was conducted over 35 days to determine the effect of live yeast supplementation in the diet of growing rabbits on growth performance and apparent nutrient digestibility.Methods: A total of 60 New Zealand and California rabbits (5 weeks old, average body weight 0.881±0.015 kg) were housed in 30 cages. They were fed with a control diet based on alfalfa and maize or barley grains and supplemented with Procreatin®7 (Saccharomyces cerevisiae CNCM I 1077) or Biosaf® SC47 (Saccharomyces cerevisiae NCYC Sc47) at three doses, namely 0, 6.4, or 12.8 ×109 CFU per kg basal diet.Result: The higher yeast concentration had a positive effect (P less than 0.01) on final body weight (BW), average daily gain (ADG) and carcass weight (CW). However, there were no significant differences in dry matter intake. As a result of this, the feed conversion ratio (FCR) decreased (P less than 0.01). Significant increases (P less than 0.05) in nutrient digestibility (DM, OM, NDF and ADF) were observed with both grains. The use of yeast in maize and barley-based diets of rabbits has positive effects on growth performance and nutrient digestibility.


Author(s):  
Nur Shafika Mohd Sairazi ◽  
K. N. S. Sirajudeen ◽  
Mustapha Muzaimi ◽  
Mummedy Swamy ◽  
Mohd Asnizam Asari ◽  
...  

Objective: The present study examined the protective effect of tualang honey (TH) against kainic acid (KA)-induced oxidative stress in the cerebellum and brainstem of rats.Methods: Male Sprague-Dawley rats were randomly divided into four groups: Control, KA-treated, TH+KA-treated, and topiramate (TPM, an antiepileptic agent)+KA-treated groups. Rats were pretreated orally with drinking water, TH (1.0 g/kg body weight), or TPM (40 mg/kg body weight), respectively, five times at 12 h intervals. Saline or KA (15 mg/kg body weight) were injected subcutaneously 30 min after last oral treatment. Rats were sacrificed at 2 h, 24 h, and 48 h after KA administration. Oxidative stress markers were analyzed in different brain regions (cerebellum and brainstem) 2 h, 24 h, and 48 h after KA administration.Results: KA caused significant (p<0.05) elevation in the thiobarbituric acid reactive substances level, protein carbonyl contents, and nitric oxide production, impairment of glutathione system, and a significant reduction in the total antioxidant status in the rat cerebellum and brainstem at multiple time-points, as compared to control groups. Pretreatment with TH significantly (p<0.05) reduced the elevation in the thiobarbituric acid reactive substances level, protein carbonyl contents, and nitric oxide production and increasing a reduction in the total antioxidant status in the rat cerebellum and brainstem induced by KA at multiple time-points, as compared to KA only-treated group.Conclusion: Taken together, this study suggests that TH has therapeutic potential in reducing oxidative stress in the cerebellum and brainstem of KA-induced rats via its antioxidant property.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Teresa Grzelak ◽  
Marta Tyszkiewicz-Nwafor ◽  
Agata Dutkiewicz ◽  
Aniceta Ada Mikulska ◽  
Monika Dmitrzak-Weglarz ◽  
...  

Introduction. The aim of the study was to assess the correlation between the levels of neuropeptide B (NPB), neuropeptide W (NPW), vaspin (VAS), and the total antioxidant status (TAS) in the blood, as well as nutritional status of patients with anorexia nervosa (AN). Materials and Methods. The study covered a cohort of 76 female teenagers, including 46 females with extreme AN and 30 healthy peers (CONTR) aged 12-17. Results. AN persons were characterized by higher (in comparison to CONTR) NPB and VAS concentrations and lower values of TAS levels, body weight, and anthropometric values. Positive correlations between NPB and VAS levels were noted in the AN group (R=0.33; p<0.001) as well as between concentrations of NPW and VAS in the same group (R=0.49; p<0.001). Furthermore, positive correlations existed between NPB and NPW concentrations across the whole studied population (AN+CONTR; R=0.75; p<0.000001), AN (R=0.73; p<0.000001) and CONTR (R=0.90; p<0.0005). Conclusions. In detailed diagnostics of AN it is worth considering testing NPB and VAS levels.


2020 ◽  
Vol 100 (4) ◽  
pp. 640-649
Author(s):  
Ji Hwan Lee ◽  
Won Yun ◽  
Han Jin Oh ◽  
Ji Seon An ◽  
Young Gwang Kim ◽  
...  

The goal of this study was to investigate effects of different levels of silicate supplementation in weaning to finishing pigs. A total of 96 piglets [(Landrace × Yorkshire) × Duroc] with initial body weight of 11.30 ± 0.02 kg were used for 16 wk (six replicate pens with four pigs per pen). Dietary treatment consisted of 0% (CON), 0.1% (T1), 0.5% (T2), and 1.0% (T3) silicate in the basal diet. Inclusion of 0.1% dietary silicate increased (P < 0.05) body weight, average daily gain, and gain-to-feed ratio in 0–16 wk. In addition, inclusion of 0.1% dietary silicate increased (P < 0.05) crude protein digestibility in 8 and 16 wk, whereas it decreased (P < 0.05) Escherichia coli count and ammonia emissions throughout the study period. Additionally, inclusion of dietary silicate increased (linear, P < 0.05) white blood cell in 4 wk, whereas it increased (quadratic, P < 0.05) white blood cell counts in 8 and 16 wk. Blood urea nitrogen decreased (quadratic, P < 0.05), and lymphocyte and foot and mouth antibodies increased (quadratic, P < 0.05) when silicate level increased. In conclusion, supplementation of 0.1% silicate in the diet showed positive effects in weaning to finishing pigs.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 279-280
Author(s):  
Sawyer Fonnesbeck ◽  
Kara J Thornton ◽  
Blair Waldron ◽  
Rusty Stott ◽  
Alexis Sweat ◽  
...  

Abstract Many breeds of dairy cattle exist, but questions remain about their relative performance within exclusively forage-based systems in the United States. This paucity of data is especially apparent in relation to heifer development, which is the second largest expense on most dairy farms. We evaluated the performance of prepubertal heifers from four different genetic backgrounds (“breeds”) within a rotational grazing system in the Intermountain West. For each of two 105-day grazing seasons, 24 dairy heifers from each of four different breeds [Holstein (HO), Jersey (JE), Holstein/Jersey crossbred (HJ), and Swedish Red/Holstein/Montbeliarde crossbred (SHM)] were randomly assigned to one of two pasture treatments that consisted of either grass only (MONO) or grass interseeded with the legume birdsfoot trefoil (BFT; MIX). Main effects of treatment and breed (and potential interactions) on heifer average daily gain (ADG), change in percent mature body weight (CPMBW), fecal egg count (FEC), rumen volatile fatty acids (VFA), and body condition scores (BCS) were evaluated. There was a significant effect of pasture treatment on ADG, with MIX heifers averaging 0.48 kg of gain/day, whereas MONO heifers averaged 0.29 kg/day (P &lt; 0.0001). Change in BCS was significantly affected by treatment (P = 0.0012) and breed (P &lt; 0.0001). Significant effects of treatment (P &lt; 0.0001), breed (P = 0.0005), and treatment*breed (P = 0.0005) on CPMBW were also found. Treatment and breed had no effect on FEC or total rumen VFA content (P &gt; 0.05). Overall, we found that Jerseys were able to gain a higher percentage of their mature body weight and lose less body condition while on pasture than heifers of other breeds. We also found that grazing BFT can have significant positive effects on ADG, BCS, and CPMBW. Further research is needed to more thoroughly evaluate the influence of heifer genetics (breed) on metrics of growth, health, reproductive performance, and production in pasture settings.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 164-166
Author(s):  
Santi Devi Upadhaya ◽  
Hyun Ju Park ◽  
Inho Kim ◽  
Hong Ik Jung ◽  
Yanjiao Li

Abstract A total of 18 sows (Landrace × Yorkshire) with an average body weight of (within 24 h after farrowing) were used for a 5- week experiment to determine the effects of varying dietary Valine, Lysine (V:L) ratios on performance and fecal score in lactating sows and litters. Sows were raised in individual pens, and assigned to one of three experimental diets consisting different concentration of Valine, Lysine ratios (0.83%, 0.85% and 0.88%). sows body weight was significantly improved by 0.85% valine and lysine ratio compared to 0.85% and 0.88%. However, no significant difference were observed on sows body weight loss, back fat thickness, average daily feed intake and days to return to estrus of sows during the three experiment period. In addition, growth performance of piglet weaning weight were significantly improved by 0.85% valine and lysine ratio compared to 0.85% and 0.88%. Morever, piglet average daily gain was significantly increased 0.88% valine and lysine ratio compared to 0.83% and 0.85%. The three dietary treatments had a significant differences (P&gt;0.05) on fecal score of sows, farrowing and 14 d old age piglets were significantly observed by valine and lisiune ratio. In conclusion, Valine, Lysine had no positive effects on the fecal score of sows and litter during lactation and also no positive effect on gut and its microflora.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 201-202
Author(s):  
Jemin Ahn ◽  
Yi Yang ◽  
In Ho Kim

Abstract The objective of the present study was to evaluate the effects of different ratios of L-Arginine and lysine on the performance of sows and their piglets. A total of 12 (Landrace×Yorkshire) sows, with an average parity of 2.3 (from 1 to 4), were subjected to 3 treatments with 4 sows per treatment. Treatments were as follows: 1) CON, Basal diet (L-arginine: Lysine= 0.95), 2) TRT1, CON + Arginine (A: L = 1), and 3) TRT2, CON + Arginine (A: L = 1.05). The supplementation of 1.05 A: L showed reduction in body weight loss after farrowing (linear, P = 0.0105), at weaning (linear, P = 0.0492), and increased the back-fat thickness loss after farrowing (0.00498) and at weaning (0.0204). Dietary supplementation of 1.05 A: L increased (linear, P = 0.0226) body weight of piglets at weaning. In addition, dietary supplementation of L-Arginine tended to increase (linear, P = 0.0103) the average daily gain (ADG) of piglets at weaning. In conclusion, dietary supplementation with L-arginine (A: L = 1.05) exerted positive effects on some of the reproductive performance parameters in sows and growth performance in suckling piglets. These findings may provide an insight into a new nutritional strategy for sows.


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