scholarly journals Organic Acids Improve Growth Performance with Potential Regulation of Redox Homeostasis, Immunity, and Microflora in Intestines of Weaned Piglets

Antioxidants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1665
Author(s):  
Xin-Dong Xiang ◽  
Zhang-Chao Deng ◽  
You-Wei Wang ◽  
Hua Sun ◽  
Li Wang ◽  
...  
Keyword(s):  
Health Status ◽  
Organic Acids ◽  
Organic Acid ◽  
Growth Performance ◽  
Redox Homeostasis ◽  
Intestinal Morphology ◽  
Mrna Levels ◽  
Water Control ◽  
Host Defense Peptides ◽  
Piglet Growth

The objective of this study is to evaluate the effects of organic acids on piglet growth performance and health status. A total of 360 weanling pigs (5.3 ± 0.6 kg) were randomly allotted to 3 treatment groups with 12 replicates of 10 pigs/pen. Piglets were fed the same basal diet and given either water (control) or water plus 2.0 L/Ton organic acid (OA) blends, such as OA1 or OA2, respectively, for 7 weeks. Compared to the control, OA1 and OA2 improved growth performance and/or reduced the piglets’ diarrhea rate during the various periods and improved small intestinal morphology at days 14 and/or 49. OA1 and OA2 also increased serum CAT and SOD activities and/or T-AOC and, as expected, decreased MDA concentration. Moreover, at day 14 and/or day 49, OA1 and OA2 increased the jejunal mRNA levels of host defense peptides (PBD1, PBD2, NPG1, and NPG3) and tight junction genes (claudin-1) and decreased that of cytokines (IL-1β and IL-2). Additionally, the two acidifiers regulated the abundance of several cecum bacterial genera, including Blautia, Bulleidia, Coprococcus, Dorea, Eubacterium, Subdoligranulum, and YRC2. In conclusion, both of the organic acid blends improved piglet growth performance and health status, potentially by regulating intestinal redox homeostasis, immunity, and microflora.

scholarly journals PSIX-15 Effects of mixture of essential oils and organic acid supplementation on growth performance, blood profiles, leg bone length and intestinal morphology in broilers

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 347-348
Author(s):  
Hanjin Oh ◽  
Shudong Liu ◽  
Won Yun ◽  
Jihwan Lee ◽  
Jiseon An ◽  
...  
Keyword(s):  
Essential Oils ◽  
Organic Acid ◽  
Growth Performance ◽  
Basal Diet ◽  
Feed Additives ◽  
Intestinal Morphology ◽  
Acid Supplementation ◽  
Bone Length ◽  
Significant Difference ◽  
Blood Profiles

Abstract This study was conducted to evaluate the effects of mixture of essential oils and organic acid supplementation on growth performance, blood profiles, leg bone length and intestinal morphology in ROSS broilers. A total of 40 Ross 308 broiler (1140 ±80g) were randomly allocated to 2 groups, basal diet (CON), basal diet+0.05% Avi-protect® (AVI), with 20 replicates every group, and 1 chicken per replicate per cage. The BW (P < 0.05) and weight gain (P < 0.05) of broilers were increased in the AVI group compared with the CON group. The content of triglyceride (P < 0.05) and LDL (P < 0.05) significantly decreased in the AVI group compared with the CON group. There was no significant difference on leg bone length between the AVI and the CON group (P > 0.05). the villi height (P < 0.05) and goblet cell count (P < 0.05) significantly increased in the AVI group compared with the CON group. In conclusion, the Avi-protect® as feed additives improved the growth performance and lipid metabolism and promoted the development of intestinal morphology in broilers.

Single components of botanicals and nature-identical compounds as a non-antibiotic strategy to ameliorate health status and improve performance in poultry and pigs

2020 ◽  
Vol 33 (2) ◽  
pp. 218-234 ◽  
Author(s):  
B. Rossi ◽  
A. Toschi ◽  
A. Piva ◽  
E. Grilli
Keyword(s):  
Health Status ◽  
Growth Performance ◽  
Bioactive Compounds ◽  
Intestinal Morphology ◽  
Organosulfur Compounds ◽  
Direct Products ◽  
Plant Materials ◽  
Pure Compounds ◽  
Raw Plant Materials ◽  
Nutritional Strategies

AbstractIn the current post-antibiotic era, botanicals represent one of the most employed nutritional strategies to sustain antibiotic-free and no-antibiotic-ever production. Botanicals can be classified either as plant extracts, meaning the direct products derived by extraction from the raw plant materials (essential oils (EO) and oleoresins (OR)), or as nature-identical compounds (NIC), such as the chemically synthesised counterparts of the pure bioactive compounds of EO/OR. In the literature, differences between the use of EO/OR or NIC are often unclear, so it is difficult to attribute certain effects to specific bioactive compounds. The aim of the present review was to provide an overview of the effects exerted by botanicals on the health status and growth performance of poultry and pigs, focusing attention on those studies where only NIC were employed or those where the composition of the EO/OR was defined. In particular, phenolic compounds (apigenin, quercetin, curcumin and resveratrol), organosulfur compounds (allicin), terpenes (eugenol, thymol, carvacrol, capsaicin and artemisinin) and aldehydes (cinnamaldehyde and vanillin) were considered. These molecules have different properties such as antimicrobial (including antibacterial, antifungal, antiviral and antiprotozoal), anti-inflammatory, antioxidant, immunomodulatory, as well as the improvement of intestinal morphology and integrity of the intestinal mucosa. The use of NIC allows us to properly combine pure compounds, according to the target to achieve. Thus, they represent a promising non-antibiotic tool to allow better intestinal health and a general health status, thereby leading to improved growth performance.

scholarly journals Effect of probiotic Pediococcus acidilactici FT28 on growth performance, nutrient digestibility, health status, meat quality, and intestinal morphology in growing pigs

2018 ◽  
pp. 1669-1676 ◽  
Author(s):  
Mamata Joysowal ◽  
B. N. Saikia ◽  
Runjun Dowarah ◽  
S. Tamuly ◽  
D. Kalita ◽  
...  
Keyword(s):  
Health Status ◽  
Growth Performance ◽  
Meat Quality ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Intestinal Morphology ◽  
Pediococcus Acidilactici ◽  
N Retention ◽  
Fermented Feed ◽  
G Ratio

Aim: The experiment was conducted to evaluate the effect of swine-origin probiotic Pediococcus acidilactici FT28 on growth, nutrient utilization, health status, meat quality and intestinal morphology in growing female pigs. Materials and Methods: Pigs (n=27) were distributed into three groups (3 replicates of 3 each) and supplemented with basal diet either without probiotics (C) or with a probiotic of dairy-based (Lactobacillus acidophilus NCDC-15; TLact) or swine based (P. acidilactici FT28; TPedic). The probiotics were fed as fermented feed at 200 g/pig/day. At the end of the trial, six pigs from each group were selected for metabolism trial and then sacrificed to determine meat quality and intestinal morphology. Results: Supplementation of both probiotics improved growth performance, whereas feed intake, digestibility of CP and N retention were better (p<0.05) in P. acidilactici FT28-fed group. However , the digestibility of dry matter (DM), organic matter (OM), ether extracts (EE), crude fibre and nitrogen free extract did not show any significant effect on probiotic supplementation. The serum A: G ratio, triglyceride, and cholesterol level were also improved (p<0.05) in TPedic group compared to other treatment groups. Both probiotic supplementations showed lower (p<0.05) serum glucose level with similar protein and albumin value, which indicated good utilization of feed as well as health status of growing pigs. Dressing percentage, vital organ weight, and EE of loin meat were higher (p<0.05) in probiotic-supplemented groups compared to control. However, P. acidilactici FT28-fed animals showed higher (p<0.05) CP and total ash percentage of meat without affecting pH, water holding capacity, and extract release volume of loin muscle. The villi height and crypt depth were better in both supplemented groups compared to control. Conclusion: Results of the present study revealed that P. acidilactici FT28 could serve as better probiotic source in swine production for the better utilization of CP and N-retention in meat with improved health status and intestinal morphology.

Effects of an organic acid mixture and methionine supplements on intestinal morphology, protein and nucleic acids content, microbial population and performance of broiler chickens

2011 ◽  
Vol 51 (11) ◽  
pp. 1025 ◽  
Author(s):  
A. A. Saki ◽  
S. M. Eftekhari ◽  
P. Zamani ◽  
H. Aliarabi ◽  
M. Abbasinezhad
Keyword(s):  
Nucleic Acids ◽  
Organic Acids ◽  
Organic Acid ◽  
Dna Content ◽  
Broiler Chickens ◽  
Microbial Population ◽  
Intestinal Morphology ◽  
Acid Mixture ◽  
Broiler Chicks ◽  
And Performance

A study was carried out to investigate the effects of dietary supplementation of an organic acids mixture and two methionine supplements on intestinal morphology, protein and nucleic acids content, microbial population and performance of broiler chickens. Six hundred unsexed day-old Ross 308 broiler chicks were used in a factorial arrangement (3 × 2) based on a completely randomised design by four replicates with 25 chicks in each. Experimental diets consisted of: 0% organic acid mixture + DL-methionine (Treatment 1), 0% organic acid mixture + Alimet (Treatment 2), 0.5% organic acid mixture + DL-methionine (Treatment 3), 0.5% organic acid mixture + Alimet (Treatment 4), 1% organic acid mixture + DL-methionine (Treatment 5) and 1% organic acid mixture + Alimet (Treatment 6). A significant increase in jejunum mucosal DNA content was found by using 1% of organic acid mixture compared with those by other levels of organic acids at 21 days of age (P < 0.05). Also Treatments 5 and 6 had a higher mucosal DNA content than other treatments (P < 0.05) in a similar period. While at grower stage, the results have shown that protein content, protein/DNA and protein/RNA ratio by 0.5 and 1% of organic acids mixture significantly increased compared with those in the 0% level (P < 0.05). The addition of 1% level of organic acid mixture significantly increased villus height compared with 0 and 0.5% level of organic acid mixture at 21 days of age (P < 0.05). Highest and lowest villus heights were obtained by Treatments 1 and 6 (P < 0.05). Crypt depth increased by 0.5 and 1% of organic acid at 21 and 42 days of age (P < 0.05). Villus surface was significantly increased by 1% of organic acid mixture compared with that by 0% level at 21 days of age. The use of organic acid levels especially 1% resulted in an increase in lactic acid bacteria and decreased Enterobacteriaceae counts in the ileum of broiler chicken (P < 0.05). Better bodyweight and feed conversion ratio were obtained (P < 0.05) by 0.5 and 1% of organic acids mixture, although no response was found in feed intake and mortality in this respect (P > 0.05). The results of this study have shown improved reactions on intestinal morphometrical parameters and microflora atmosphors, by using 1% organic acid mixture. In contrast no differences were found between Alimet and DL-methionine in all tested parameters.

scholarly journals Supplementation of Mixed Organic Acids Improves Growth Performance, Meat Quality, Gut Morphology and Volatile Fatty Acids of Broiler Chicken

Animals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3020
Author(s):  
Jiayu Ma ◽  
Jian Wang ◽  
Shad Mahfuz ◽  
Shenfei Long ◽  
Di Wu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Organic Acids ◽  
Growth Performance ◽  
Meat Quality ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Average Daily Gain ◽  
Intestinal Morphology ◽  
Final Body Weight ◽  
Fatty Acids Profile

Background: Organic acid as a green feed additive is increasingly favoured by enterprises and scholars, but little emphasis has been placed on the effect of organic acids on broiler meat quality. Methods: A total of 192 male chicks (one-day-old, weighted 48.40 ± 0.64 g) were selected to investigate the effect of mixed organic acids (MOA) on growth performance, meat quality as well as fatty acids profile. Chicks were randomly allocated to three treatments with eight replicates and eight chicks per replicate, including a corn–soybean basal diet with 0 (CON), 3000 mg/kg (low MOA; LMOA), and 6000 mg/kg (high MOA; HMOA) MOA. The experiment was divided into starter (d 1–d 21) and grower (d 22–d 42) phases. Results: Broilers supplemented with LMOA and HMOA enhanced (p < 0.05) the final body weight and average daily gain in the grower and overall phases. An improved (p < 0.05) feed conversion ratio in the grower and overall phases was observed in broilers supplemented with LMOA. The breast and thigh muscles pH24h were higher (p < 0.05) in broilers fed with HMOA and the redness in thigh meat was also improved (p < 0.05). Additionally, supplementing LMOA increased (p < 0.05) the saturated fatty acids, unsaturated fatty acids and the ratio of polyunsaturated fatty acids to saturated fatty acids in breast meat. A positive effect occurred (p < 0.05) on jejunal villus height and ileal crypt depth in 21 d broilers supplemented with HMOA. Conclusion: Our findings indicated that dietary supplementation of MOA could improve the growth performance, meat quality, and fatty acids profile, as well as intestinal morphology. Furthermore, diets supplemented with mixed organic acids at 3000 mg/kg may be more desirable, considering the overall experimental results in broilers.

EMPREGO DE UMA MISTURA DE ÁCIDOS FUMÁRICO, LÁTICO, CÍTRICO E ASCORBICO EM DIETAS INICIAIS DE FRANGOS DE CORTE

2004 ◽  
Vol 9 (1) ◽  
Author(s):  
A. MAIORKA ◽  
A.M.E. SANTIN ◽  
S.A. BORGES ◽  
M. OPALINSKI ◽  
A.V.F. SILVA
Keyword(s):  
Organic Acids ◽  
Organic Acid ◽  
Intestinal Morphology ◽  
Growth Promoter ◽  
Growth Promoters ◽  
Acid Supplementation ◽  
Lipid Utilization ◽  
Animal Metabolism ◽  
Poultry Diets ◽  
Ascorbic Acids

Foram realizados três experimentos com o objetivo de avaliar o melhor uso de uma mistura de ácidos fumárico, lático, cítrico e ascórbico na dieta de aves jovens. No experimento I, aves foram submetidas a dieta com e sem uma mistura de ácidos orgânicos e foi avaliada a influência destes ácidos orgânicos sobre o desempenho e morfologia da mucosa intestinal de frangos de corte. O experimento II avaliou o uso da mistura de ácidos orgânicos na substituição de promotores de crescimento (antibióticos) em dieta de aves. Para tanto as aves foram submetidas a três tratamentos: T1, dieta com promotores de crescimento; T2, dieta sem promotores de crescimento e suplementados com a mistura de ácidos orgânicos; e T3, dieta com a mistura de ácidos orgânicos e com promotor de crescimento. O experimento III buscou verificar se ácidos orgânicos poderiam melhorar utilização dos lipídios e para tanto aves foram submetidas a um experimento fatorial 2 X 2 tendo dois níveis de energia (2.900 e 3.200 kcal/ ME) e dois níveis da mistura de ácidos orgânicos (0,05% e 0%). Os resultados observados demonstraram que ácidos orgânicos foram capazes de melhorar o desempenho de aves de 1 a 21 dias de idade até mesmo na ausência do promotor de crescimento na dieta, entretanto não apresentaram nenhum efeito sobre a morfologia intestinal das aves, bem como sobre a utilização dos lipídios em aves até os 21 dias de vida. Evaluation of a mix of fumaric, lactic, citric and ascorbic acids on start diets of broilers Abstract Three experiments were carried out in order to evaluate the effect of different organic acids of the animal metabolism, namely fumaric, lactic, citric and ascorbic acids, added to the diet of young broilers. In the first experiment a group of birds were fed with or without a mix of those organic acids to evaluate its effect on their performance and their intestinal morphology. In experiment II, it has been evaluated the effect of the mix of those organic acids as growth promoter (antibiotic) substitute in poultry diets. In this experimental, three diets were used, T1, a diet with growth promoters, T2 diet a diet without growth promoters but supplemented with a mix of organic acid and T3, a diet supplemented with growth promoter and mix of organic acids. Experiment III was carried out aiming to verify if the organic acids in study could improve fat digestibility and for that a factorial 2 X 2 design was carried out with two levels of energy and two levels of organic acid supplementation. The results showed that the mix of organic acids improved the birds performance, even in the absence of antibiotic, no effects being observed in regard to the intestinal morphology and lipid utilization.

scholarly journals Probiotics in Rabbit Farming: Growth Performance, Health Status, and Meat Quality

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3388
Author(s):  
Simone Mancini ◽  
Gisella Paci
Keyword(s):  
Immune Response ◽  
Health Status ◽  
Growth Performance ◽  
Meat Quality ◽  
Volatile Fatty Acids ◽  
Critical Role ◽  
Intestinal Morphology ◽  
Live Performance ◽  
Feed Conversion ◽  
Positive Effects

The rabbit’s complex microbiota of the gastrointestinal tract (GIT) plays a critical role in feed digestion, in vitamin production, in fermentative activity with production of volatile fatty acids, and stimulation of immune response, as well as in the infection defence against pathogens and countering environmental stresses. To prevent digestive disorders of this fragile ecosystem, rabbit breeders adopt suitable diets supplemented with additives such as probiotics. Probiotics can interact with the host and with the other microflora leading to an increased health status. A review on the effects of probiotics on rabbit growth performance, health status, and meat quality was conducted to reduce the incidence of digestive diseases and enhance productive performance. Some authors observed that the supplementation of probiotics to the diet improved feed conversion ratio and growth and digestion coefficients, while other authors reported a lack of effect on the live performance. Benefits derived from the use of probiotics were observed on the mortality and the morbidity. The studies performed, to evaluate the effects of probiotic supplementation in diets on the immune response, showed variations in the results. Some authors reported no significant effect on haematological parameters, such as total protein, immunoglobulins, and IgG, while others observed a significant increase or decrease of the same parameters. Most of the research reported significant modifications of intestinal morphology and positive effects on the GIT microbiota, supporting the host’s natural defences. Regarding the carcass and meat quality, the studies reported only partial and opposing results.

Impact of feeding blends of organic acids and herbal extracts on growth performance, gut microbiota and digestive function in newly weaned pigs

2004 ◽  
Vol 84 (4) ◽  
pp. 697-704 ◽  
Author(s):  
H. Namkung ◽  
M. Li J. Gong ◽  
H. Yu ◽  
M. Cottrill ◽  
C. F. M. de Lange
Keyword(s):  
Immune Response ◽  
Gut Microbiota ◽  
Organic Acids ◽  
Growth Performance ◽  
Dietary Treatment ◽  
Intestinal Morphology ◽  
Herbal Extract ◽  
Coliform Bacteria ◽  
Herbal Extracts ◽  
Weaned Pigs

One hundred eighty newly weaned pigs were used to inves tigate effects of feeding organic acids and herbal extracts on growth performance, gut morphology and microbiota, and immune response in newly weaned pigs during a 4-wk period. There were five dietary treatments: control, Acid 1 (acetic, propionic, phosphoric and citric acid; 1.1% inclusion), Acid 2 (Acid 1 + 1.0% lactic acid), herbal extracts (0.75% inclusion; containing cinnamon, thyme and oregano extract), and antibiotic (110 ppm lincomycin). As compared to the control, pigs on antibiotic and Acid 2 showed higher (P < 0.05) ADG only during week 2 post-weaning, whereas pigs on herbal extract showed lower (P < 0.05) ADG only during week 3 post-weaning. Fecal coliform counts were lower (P < 0.08) in pigs on Acid 1 and 2 on day 4 post-weaning and in pigs on antibiotic and herbal extract on day 14 post-weaning. Fecal lactobacilli counts were lower (P < 0.05) in pigs on antibiotic on day 14 post-weaning. Based on PCR-DGGE, treatment influenced the composition of gut microbiota. The pH of the colon was lower (P < 0.05) in pigs on acid treatments and serum IgG was lower (P < 0.05) in pigs on antibiotic. Dietary treatment did not affect (P > 0.10) intestinal morphology. These results show that the inclusion of antibiotic in the diet reduced the proliferation of both potentially harmful coliform bacteria and potentially beneficial lactobacilli in the pig’s gut, while herbal extract and organic acids appeared to reduce the proliferation of coliform bacteria. Blends of organic acids can serve as an alternative to in-feed antibiotics during the first few weeks post-weaning for pigs. Key words: Piglet, organic acids, herb, microbiota, immune response, intestinal morphology

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