scholarly journals Emerging Strategies to Protect the Skin from Ultraviolet Rays Using Plant-Derived Materials

Antioxidants ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 637 ◽  
Author(s):  
Yong Chool Boo
Keyword(s):  
Uv Light ◽  
Skin Aging ◽  
The Body ◽  
Ultraviolet Rays ◽  
Skin Damage ◽  
Melanin Production ◽  
Defense Strategies ◽  
Future Studies ◽  
Sunscreen Product ◽  
Uv Rays

Sunlight contains a significant amount of ultraviolet (UV) ray, which leads to various effects on homeostasis in the body. Defense strategies to protect from UV rays have been extensively studied, as sunburn, photoaging, and photocarcinogenesis are caused by excessive UV exposure. The primary lines of defense against UV damage are melanin and trans-urocanic acid, which are distributed in the stratum corneum. UV rays that pass beyond these lines of defense can lead to oxidative damage. However, cells detect changes due to UV rays as early as possible and initiate cell signaling processes to prevent the occurrence of damage and repair the already occurred damage. Cosmetic and dermatology experts recommend using a sunscreen product to prevent UV-induced damage. A variety of strategies using antioxidants and anti-inflammatory agents have also been developed to complement the skin’s defenses against UV rays. Researchers have examined the use of plant-derived materials to alleviate the occurrence of skin aging, diseases, and cancer caused by UV rays. Furthermore, studies are also underway to determine how to promote melanin production to protect from UV-induced skin damage. This review provides discussion of the damage that occurs in the skin due to UV light and describes potential defense strategies using plant-derived materials. This review aims to assist researchers in understanding the current research in this area and to potentially plan future studies.

scholarly journals PREPARATION AND EVALUATION OF DEEP CLEANSING EXFOLIATOR

2018 ◽  
Vol 11 (7) ◽  
pp. 256
Author(s):  
Fatima Grace X ◽  
Anbarasan B ◽  
Kanimozhi T ◽  
Shanmuganathan S
Keyword(s):  
Major Part ◽  
Climatic Changes ◽  
The Body ◽  
Marine Phytoplankton ◽  
Ultraviolet Rays ◽  
Skin Damage ◽  
Kiwi Fruit ◽  
Environmental Causes ◽  
Skin Care Products ◽  
Preparation And Evaluation

Objectives: The objective of the present study is to formulate an exfoliant using natural ingredients along with diatoms. Skin care products are important factor to improve confidence in individuals. Health of an individual is mainly represented by skin which is the major part of the body. Skin can be affected by several environmental factors such as ultraviolet rays, pollution, dust, and climatic changes that can intensify issues related to skin. Environmental causes can be prevented from skin damage by treating with topical application of synthetic or herbal cosmetics.Methods: In this preparation, diatoms are used, derived from marine phytoplankton which may contain a small quantity of muddy sludge, sand, and debris. Other natural ingredients are kiwi fruit, almond, and coffee seeds. Esthetic ingredients used in this preparation include pH modifiers, viscolysers, and surfactants. Among these ingredients, diatoms and coffee seeds attribute to the exfoliating activity of the preparation.Results: The prepared gel was evaluated for various parameters such as color, odor, consistency, pH, viscosity, spreadability, washability, grittiness, foamability, irritability, and extrudability. The results were found to be satisfactory.Conclusion: The present work was attempted to make a herbal exfoliant using suitable base to form a gel. Since diatoms are natural exfoliating agent, they are incorporated into the formulation which increases the efficiency of the product. Various parameters have been evaluated providing satisfactory result and improve the appearance of the skin without any side effects.

scholarly journals Skin Rejuvenation Profile in Dr. Soetomo General Hospital Surabaya

2019 ◽  
Vol 3 (12) ◽  
pp. 475-479
Author(s):  
Lutfia Ariska Ramadhani ◽  
Trisniartami Setyaningrum ◽  
Etty Hary Kusumastuti
Keyword(s):  
General Hospital ◽  
Aging Process ◽  
Uv Light ◽  
Intrinsic Factor ◽  
Skin Aging ◽  
The Body ◽  
Skin Rejuvenation ◽  
Extrinsic Factors ◽  
Tissue Changes ◽  
Poor Nutrition

Skin aging is a condition in which cell and tissue changes occur due to mechanism abnormalities and a decrease in function of a tissue which can be triggered by intrinsic or extrinsic factors. Intrinsic factor is an aging process which originates from the body of an individual itself while extrinsic factor is an aging process caused by factors from the outside, such as excessive exposure to the UV light, smoking, or poor nutrition. Skin rejuvenation therapy, hopefully, would be able to restore or even slow down the aging process itself. This research was a descriptive observational using retrospective approach based on patients’ medical record in the Outpatient Clinic of Dermatology and Venereology Department in Dr. Soetomo General Hospital Surabaya in January to December 2017. This study obtained 203 samples (198 women/females and 5 men/males) with the most age group ranging from 45-

scholarly journals Protective Effects of Kuding Tea (Ilex kudingcha C. J. Tseng) Polyphenols on UVB-Induced Skin Aging in SKH1 Hairless Mice

Molecules ◽  
2019 ◽  
Vol 24 (6) ◽  
pp. 1016 ◽  
Author(s):  
Ruokun Yi ◽  
Jing Zhang ◽  
Peng Sun ◽  
Yu Qian ◽  
Xin Zhao
Keyword(s):  
Uv Light ◽  
Skin Aging ◽  
Ultraviolet B ◽  
Tissue Inhibitor Of Metalloproteinase ◽  
Matrix Metalloproteinase 2 ◽  
Precipitation Method ◽  
Protective Effects ◽  
Skin Damage ◽  
Hairless Mice ◽  
Necrosis Factor Alpha

In this study, the protective effects of Kuding tea polyphenols (KTPs) on ultraviolet B (UVB)-induced skin injury of SKH1 hairless mice were studied. The ion precipitation method was used for extraction of polyphenols from Kuding tea. High-performance liquid chromatography showed that KTPs contains chlorogenic acid, cryptochlorogenic acid, isochlorogenic acid B, isochlorogenic acid A, and isochlorogenic acid C. SKH1 hairless mice were induced skin aging using 2.0 mW/s intensity of 90 mJ/cm2 UV light once a day for seven weeks. The 2.5% and 5% KTPs solution was smeared on 2 cm2 of back skin of skin aging mice twice a day. Mouse experiments showed that KTP strongly increased the serum levels of total superoxide dismutase (T-SOD) and catalase (CAT) and reduced those of malondialdehyde, interleukin 6 (IL-6), IL-1β, and tumor necrosis factor alpha (TNF-α) in mice with UVB-induced skin damage. KTP also increased the levels of type 1 collagen (Col I), hydroxyproline, and hyaluronic acid and reduced those of Col III and hydrogen peroxide in the damaged skin tissues of mice. Pathological observations of tissues stained with H & E, Masson’s trichrome, Verhoeff, and toluidine blue showed that KTPs could protect skin cells, collagen, and elastin and decrease the number of mast cells, thus inhibiting skin damage. Quantitative PCR and western blot assays showed that KTP upregulated the mRNA and protein expression of tissue inhibitor of metalloproteinase 1 (TIMP-1), TIMP-2, copper/zinc-SOD, manganese-SOD, CAT, and glutathione peroxidase and downregulated the expression of matrix metalloproteinase 2 (MMP-2) and MMP-9. In addition, the same concentration of KTP had stronger protective effects than vitamin C. The results of this study demonstrate that KTPs have good skin protective effects, as they are able to inhibit UVB-induced skin damage.

Skin Health from the Inside Out

2020 ◽  
Vol 11 (1) ◽  
pp. 235-254 ◽  
Author(s):  
Brittany Woodby ◽  
Kayla Penta ◽  
Alessandra Pecorelli ◽  
Mary Ann Lila ◽  
Giuseppe Valacchi
Keyword(s):  
Dietary Supplementation ◽  
Skin Aging ◽  
The Body ◽  
Antioxidant Compounds ◽  
Oxygen Species ◽  
Skin Damage ◽  
Inflammatory Signaling ◽  
Defense Systems ◽  
Inside Out ◽  
Endogenous Defense

The skin is the main interface between the body and the environment, providing a biological barrier against an array of chemical and physical pollutants (e.g., ultraviolet light, ozone, etc.). Exposure of the skin to these outdoor stressors generates reactive oxygen species (ROS), which can overwhelm the skin's endogenous defense systems (e.g., catalase, vitamins C and E, etc.), resulting in premature skin aging due to the induction of DNA damage, mitochondrial damage, lipid peroxidation, activation of inflammatory signaling pathways, and formation of protein adducts. In this review, we discuss how topical application of antioxidants, including vitamins C and E, carotenoids, resveratrol, and pycnogenol, can be combined with dietary supplementation of these antioxidant compounds in addition to probiotics and essential minerals to protect against outdoor stressor-induced skin damage, including the damage associated with aging.

scholarly journals Protective Effect of Spirulina-Derived C-Phycocyanin against Ultraviolet B-Induced Damage in HaCaT Cells

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 273
Author(s):  
Young Ah Jang ◽  
Bo Ae Kim
Keyword(s):  
Antioxidant Defense System ◽  
Skin Aging ◽  
Ultraviolet B ◽  
Control Group ◽  
Hacat Cells ◽  
Uvb Radiation ◽  
Skin Damage ◽  
Blue Green Algae ◽  
Radiation Group ◽  
Skin Wrinkles

Background and objectives: Reactive oxygen species (ROS) overwhelm the antioxidant defense system, induce oxidative stress, and increase matrix metalloproteinase (MMP) expression, resulting in skin aging. Thus, preventing ultraviolet B (UVB)-induced skin damage can attenuate skin aging. Spirulina (a biomass of cyanobacteria, also called blue-green algae) is comprised of prokaryotes, whereas microalgae are eukaryotes and are rich in phycocyanin, a powerful antioxidant. Materials and Methods: Here, we investigated the photoprotective effects of spirulina-derived C-phycocyanin (C-PC) against UVB radiation using keratinocytes (HaCaT cells). Results: UVB radiation increased MMP-1 and MMP-9 expression but decreased involucrin, filaggrin, and loricrin expression. C-PC showed no toxicity at concentrations of 5–80 μg/mL in terms of HaCaT cell viability. UVB-irradiated HaCaT cells had a 50.8% survival rate, which increased to 80.3% with C-PC treatment. MMP expression increased with UVB treatment, whereas MMP-1 and MMP-9 concentrations decreased with C-PC treatment. UVB reduced involucrin, filaggrin, and loricrin expression in HaCaT cells, but 80 μg/mL C-PC increased their expression by >25%. In the UVB radiation group, dichlorofluorescin diacetate fluorescence intensity in HaCaT cells increased by 81.6% compared with that in the control group, whereas ROS production was reduced by 51.2% and 55.1% upon treatment with 40 and 80 μg/mL C-PC, respectively. Conclusions: C-PC might reduce or prevent skin aging by reducing UVB irradiation-induced skin wrinkles and free radicals.

UV light and skin aging

2014 ◽  
Vol 29 (3) ◽  
Author(s):  
Jéssica Eleonora Pedroso Sanches Silveira ◽  
Débora Midori Myaki Pedroso
Keyword(s):  
Uv Light ◽  
Skin Aging

scholarly journals A Left-Sided Prevalence of Lentigo Maligna: A UK Based Observational Study and Review of the Evidence

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Mark Gorman ◽  
Andrew Hart ◽  
Bipin Mathew
Keyword(s):  
Risk Factor ◽  
Uv Light ◽  
Light Exposure ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Evidence Base ◽  
The Body ◽  
Cumulative Exposure ◽  
Lentigo Maligna ◽  
Recent Trends

Skin cancer has been shown to present asymmetrically, prevalent on the left side of the body, more so in subtypes of cutaneous melanoma such as lentigo maligna. Biases have been linked to cumulative UV light exposure and automobile driving patterns. Though left-right ratios have previously correlated with the side men or women tend to position themselves or countries drive on, more recent trends indicate a consistent left-sided bias. To clarify reasons for changing trends, a review of the evidence base and LM’s laterality in a UK cohort (99 cases 2000–2011) was conducted for the first time. The strong correlation of left-sided excess, found in both genders (ratios 1.381–1.5,P<0.05  X20.841), is congruent with more recent findings. Though evidence indicates that driving position is no longer a risk factor for LM, due most likely to improved car window UV protection, it remains the most commonly attributed cause. Understanding phenomena such as UV lights “scatter effect” or that cumulative exposure may not be a significant risk factor helps rationalize older conclusions that would otherwise appear contradictory. The reasons for left-sided excess remain unclear but may be due to factors requiring further research such as the body’s anatomical/embryological asymmetry.

scholarly journals A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders

2020 ◽  
Vol 16 (12) ◽  
pp. e1008484
Author(s):  
Ryan Smith ◽  
Rayus Kuplicki ◽  
Justin Feinstein ◽  
Katherine L. Forthman ◽  
Jennifer L. Stewart ◽  
...  
Keyword(s):  
Substance Use ◽  
Computational Model ◽  
Substance Use Disorders ◽  
The Body ◽  
Breath Holding ◽  
Healthy Individuals ◽  
Prior Beliefs ◽  
Future Studies ◽  
Psychiatric Conditions ◽  
Processing Mechanisms

Recent neurocomputational theories have hypothesized that abnormalities in prior beliefs and/or the precision-weighting of afferent interoceptive signals may facilitate the transdiagnostic emergence of psychopathology. Specifically, it has been suggested that, in certain psychiatric disorders, interoceptive processing mechanisms either over-weight prior beliefs or under-weight signals from the viscera (or both), leading to a failure to accurately update beliefs about the body. However, this has not been directly tested empirically. To evaluate the potential roles of prior beliefs and interoceptive precision in this context, we fit a Bayesian computational model to behavior in a transdiagnostic patient sample during an interoceptive awareness (heartbeat tapping) task. Modelling revealed that, during an interoceptive perturbation condition (inspiratory breath-holding during heartbeat tapping), healthy individuals (N = 52) assigned greater precision to ascending cardiac signals than individuals with symptoms of anxiety (N = 15), depression (N = 69), co-morbid depression/anxiety (N = 153), substance use disorders (N = 131), and eating disorders (N = 14)–who failed to increase their precision estimates from resting levels. In contrast, we did not find strong evidence for differences in prior beliefs. These results provide the first empirical computational modeling evidence of a selective dysfunction in adaptive interoceptive processing in psychiatric conditions, and lay the groundwork for future studies examining how reduced interoceptive precision influences visceral regulation and interoceptively-guided decision-making.

scholarly journals The role of local retinoids in eliminating signs of skin aging

2021 ◽  
Vol 97 (4) ◽  
pp. 60-70
Author(s):  
Vera I. Albanova
Keyword(s):  
Skin Irritation ◽  
Skin Neoplasms ◽  
Skin Aging ◽  
Biological Aging ◽  
Ultraviolet Rays ◽  
Entire Group ◽  
Chronological Aging ◽  
Slowing Down ◽  
Complex Process ◽  
The Many

Skin aging is a complex process involving both internal (chronological aging) and external (biological aging) factors. Slowing down the proliferative and immune processes in the epidermis, reducing the activity of fibroblasts and vascularization of the dermis during chronological aging lead to thinning, dryness, hypersensitivity, vulnerability and superficial wrinkles. Exposure to ultraviolet rays, pollutants, climate, and thermal factors cause keratinocyte disorganization, enhanced melanogenesis, collagen dystrophy, solar elastosis, and disorder of microcirculation. The main signs of external skin aging are deep wrinkles, sagging, pigmentation, telangiectasia, skin neoplasms. Among the local anti-aging agents, retinoids occupy a leading place, as they eliminate the main signs of skin aging. Of the entire group of retinoids, retinoic acids are the most active. However, the possibility of skin irritation limits their use. Therapeutic and cosmetic products with retinol esters (retinol palmitate) have a minimal irritating effect and can be used both for the prevention of skin aging and the elimination of its signs. Oral use of isotretinoin as an anti-aging agent is undesirable due to the many side effects and contraindications.

The essential role of nesfatin-1 as a biological signal on the body systems

2021 ◽  
pp. 113-118
Keyword(s):  
Metabolic Disorders ◽  
Clinical Medicine ◽  
The Body ◽  
World Population ◽  
Peripheral Tissues ◽  
Future Studies ◽  
Body Organ ◽  
Regulate Food Intake ◽  
System Today

Nesfatin-1is first described in 2006 as an anorectic peptide and regulate food intake. In following years, the studies demonstrated the presence of nesfatin-1 in central and various peripheral tissues. Thus, nesfatin-1 popularity increasing widely in clinical medicine, especially in cardiology, neurology, reproduction, metabolic disorders, psychiatric disorders, gastrointestinal system. Today, the main point concerning nesfatin-1 action in body organ and systems is concentrate its biological signals effects. Thus the increasing knowledge in these area will be highlighted for future studies especially in serious health problem all over the world population.

Sign in / Sign up

Export Citation Format

Share Document