scholarly journals Antidiabetic Potential of Medicinal Plants and Their Active Components

Biomolecules ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 551 ◽  
Author(s):  
Salehi ◽  
Ata ◽  
V. Anil Kumar ◽  
Sharopov ◽  
Ramírez-Alarcón ◽  
...  

Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds.

Author(s):  
DIPALI P SHELKE ◽  
VIJAYENDRA SWAMY SM

Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Fourth leading causes of death in the most advanced countries and there, in other emerging and recently industrialized nations, still controlled the epidemic. Inadequate control of blood sugar has significant consequences for well-being. Ayurveda and other Indian writing referenced the utilized of plants in the treatment of different diseases. Medicinal plant with antidiabetic potential has been recent area of research. The efficiency of these medicinal plants may regulate the diabetic metabolic abnormalities. This work would help researchers to choose potential herbal for diabetic treatment.


Agriculture ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 543 ◽  
Author(s):  
Beata Zimowska ◽  
Monika Bielecka ◽  
Barbara Abramczyk ◽  
Rosario Nicoletti

In the aim of implementing new technologies, sustainable solutions and disruptive innovation to sustain biodiversity and reduce environmental pollution, there is a growing interest by researchers all over the world in bioprospecting endophytic microbial communities as an alternative source of bioactive compounds to be used for industrial applications. Medicinal plants represent a considerable source of endophytic fungi of outstanding importance, which highlights the opportunity of identifying and screening endophytes associated with this unique group of plants, widespread in diverse locations and biotopes, in view of assessing their biotechnological potential. As the first contribution of a series of papers dedicated to the Lamiaceae, this article reviews the occurrence and properties of endophytic fungi associated with sages (Salvia spp.).


2018 ◽  
Vol 73 (6) ◽  
pp. 388-400
Author(s):  
Polina K. Miroshnikova ◽  
Alexey V. Lyundup ◽  
Nikolay P. Batsalenko ◽  
Mikhail E. Krasheninnikov ◽  
Yuanyuan Zhang ◽  
...  

Nerve damage is a common severe trauma caused by a complete or partial disruption of the integrity of the nerve trunk and appropriate dissociation of the CNS and denervated tissue. «Golden standard» in the treatment of extensive injuries of peripheral nerves is the use of autografts of nerve fibers, but when they are used, pathological disturbances appear in the donor zone and the results of surgical treatment are not always satisfactory. Currently, an alternative to the traditional method is the use of nerve conduits (conductors) for directed regeneration of axons. In this work, the results of the application of nerve conductors from various materials and with various biologically active components in preclinical and clinical studies, as well as conduits used in clinical practice, were analyzed. The efficiency of regeneration was compared, on the basis of the analysis the conductor most suitable for successful nerve regeneration was selected, including approaches for creating innervated tissue engineered constructs. In this work, we have collected research on nerve conductors from various materials with various prescribed properties using certain factors used to treat damage to the peripheral nervous system, showing all the advantages and disadvantages of their use, which makes it possible to develop and create a conduit that meets all the requirements of modern regenerative medicine.


Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 3042
Author(s):  
Aswir Abd Rashed ◽  
Devi-Nair Gunasegavan Rathi

The utilization of therapeutic plants is expanding around the globe, coupled with the tremendous expansion of alternative medicine and growing demand in health treatment. Plants are applied in pharmaceuticals to preserve and expand health—physically, mentally and as well as to treat particular health conditions and afflictions. There are more than 600 families of plants identified so far. Among the plants that are often studied for their health benefit include the genus of Salvia in the mint family, Lamiaceae. This review aims to determine the bioactive components of Salvia and their potential as antidiabetic agents. The search was conducted using three databases (PubMed, EMBASE and Scopus), and all relevant articles that are freely available in the English language were extracted within 10 years (2011–2021). Salvia spp. comprises many biologically active components that can be divided into monoterpenes, diterpenes, triterpenes, and phenolic components, but only a few of these have been studied in-depth for their health benefit claims. The most commonly studied bioactive component was salvianolic acids. Interestingly, S. miltiorrhiza is undoubtedly the most widely studied Salvia species in terms of its effectiveness as an antidiabetic agent. In conclusion, we hope that this review stimulates more studies on bioactive components from medicinal plants, not only on their potential as antidiabetic agents but also for other possible health benefits.


2021 ◽  
Author(s):  
Aanchal Bansal ◽  
Chinmayee Priyadarsini

Phytochemicals are produced by plants as a defence mechanism against pathogens. They are used to treat various metabolic, immunological and neurological disorders in humans in various parts of the world as a part of traditional medicine. The use of indigenous plants in commercial medicine is rising with increasing population. The antimicrobial properties of plant extracts led to increased demands. Plant tissue culture on the other hand, has proved to be a reliable alternative for the production of bioactive compounds from plants. Artificial plant culture can enhance the production of phytochemicals in medicinal plants. This review focuses on the medicinal properties of phytochemicals and their in-vitro production.


Author(s):  
Prashant Nishad ◽  
Amiya Bhonsle ◽  
Chandrakar Anchal

The health promotive, disease preventive and rejuvenation approach available in the Indian system of medicine that is known as ‘Ayurveda’, which is gaining greater attention and popularity in many regions of the world. Ayurvedic pharmacology classifies medicinal plants into different groups according to their actions.  One of these is the ‘Rasayana’. It deals with the preservation and promotion of the health by revitalizing the metabolism and enhancing the immunity. In Kashyap samnhita sutrasthan Swarna prashana samskar is a unique method of giving swarna bhasma mixed with honey and ghrita that is fortified with herbal extract to children orally. This process promotes overall growth in a natural way. This paper deals with the process of Swarna prashan sanskara, its uses the role of the Swarna with the other drugs, ingredients in the children, and also to determinate Swarna prashana as a natural immunization process.


2019 ◽  
Vol 8 ◽  
pp. 1285
Author(s):  
Jamshid Shayanfar ◽  
Hassan Ghasemi ◽  
Seyed Saeed Esmaili ◽  
Fatemeh Alijaniha ◽  
Ali Davati

Vision impairment is an important general health issue that imposes many costs on governments and the health system every year. Despite the decline in infectious eye diseases, which has reduced the vision impairment and blindness over the past two decades, vision impairment is still a major health problem in some parts of the world. In traditional medicine books, visual weakness is referred to as “any disturbance in the act of seeing”. Many medicinal herbs have been mentioned in books of Traditional Iranian medicine (TIM) for the management of vision impairment. The aim of this study is to review the medicinal plants mentioned in TIM, which are considered effective for the treatment of vision impairment or its enhancement. In this library-based study, medicinal plants effective in the treatment of vision impairment were searched using 6 valid sources of traditional medicine, including Makhzan ol-Adawiya, The Canon of Medicine, Tuhfat al-Momenin, Al-Abniyah An Haqaiq al-adwiya, Al-Shamil Fi al-Sana’at al-tebiyah, and Ekhtiarate Badiee. This was done in 10 steps (finding keywords, searching for resources, preparing a single list, finding synonyms, classifying, reviewing, extracting plants from compositions, summarizing, scoring and sorting based on the obtained score). A total of 89 medicinal plants were extracted, most of which had a hot and dry temperament. Based on the obtained score, 12 plants got the highest scores (10 and above). The extracted plants can be the basis for further clinical studies to make new effective drugs for the prevention and treatment of vision impairment.[GMJ.2019;8:e1285]


Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5805
Author(s):  
Olga Babich ◽  
Stanislav Sukhikh ◽  
Artem Pungin ◽  
Svetlana Ivanova ◽  
Lyudmila Asyakina ◽  
...  

This paper studies modern methods of producing and using callus, suspension cells and root cultures of medicinal plants in vitro. A new solution for natural product production is the use of an alternative source of renewable, environmentally friendly raw materials: callus, suspension and root cultures of higher plants in vitro. The possibility of using hairy root cultures as producers of various biologically active substances is studied. It is proven that the application of the genetic engineering achievements that combine in vitro tissue culture and molecular biology methods was groundbreaking in terms of the intensification of the extraction process of compounds significant for the medical industry. It is established that of all the callus processing methods, suspension and root cultures in vitro, the Agrobacterium method is the most widely used in practice. The use of agrobacteria has advantages over the biolistic method since it increases the proportion of stable transformation events, can deliver large DNA segments and does not require special ballistic devices. As a result of the research, the most effective strains of agrobacteria are identified.


TEKNOSASTIK ◽  
2018 ◽  
Vol 14 (2) ◽  
pp. 1
Author(s):  
Dina Amelia

There are two most inevitable issues on national literature, in this case Indonesian literature. First is the translation and the second is the standard of world literature. Can one speak for the other as a representative? Why is this representation matter? Does translation embody the voice of the represented? Without translation Indonesian literature cannot gain its recognition in world literature, yet, translation conveys the voice of other. In the case of production, publication, or distribution of Indonesian Literature to the world, translation works can be very beneficial. The position of Indonesian literature is as a part of world literature. The concept that the Western world should be the one who represent the subaltern can be overcome as long as the subaltern performs as the active speaker. If the subaltern remains silent then it means it allows the “representation” by the Western.


Author(s):  
Iia Fedorova

The main objective of this study is the substantiation of experiment as one of the key features of the world music in Ukraine. Based on the creative works of the brightest world music representatives in Ukraine, «Dakha Brakha» band, the experiment is regarded as a kind of creative setting. Methodology and scientific approaches. The methodology was based on the music practice theory by T. Cherednychenko. The author distinguishes four binary oppositions, which can describe the musical practice. According to one of these oppositions («observance of the canon or violation of the canon»), the musical practices, to which the Ukrainian musicology usually classifies the world music («folk music» and «minstrel music»), are compared with the creative work of «Dakha Brakha» band. Study findings. A lack of the setting to experiment in the musical practices of the «folk music» and «minstrel music» separates the world music musical practice from them. Therefore, the world music is a separate type of musical practice in which the experiment is crucial. The study analyzed several scientific articles of Ukrainian musicologists on the world music; examined the history of the Ukrainian «Dakha Brakha» band; presented a list of the folk songs used in the fifth album «The Road» by «Dakha Brakha» band; and showed the degree of the source transformation by musicians based on the example of the «Monk» song. The study findings can be used to form a comprehensive understanding of the world music musical practice. The further studies may be related to clarification of the other parameters of the world music musical practice, and to determination of the experiment role in creative works of the other world music representatives, both Ukrainian and foreign. The practical study value is the ability to use its key provisions in the course of modern music in higher artistic schools of Ukraine. Originality / value. So far, the Ukrainian musicology did not consider the experiment role as the key one in the world music.


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