scholarly journals Patient and Therapist In-Session Cortisol as Predictor of Post-Session Patient Reported Affect

2021 ◽  
Vol 11 (11) ◽  
pp. 1483
Author(s):  
Eyal Levi ◽  
Susanne Fischer ◽  
Hadar Fisher ◽  
Roee Admon ◽  
Sigal Zilcha-Mano

The importance of the role of affect in psychotherapy for major depressive disorder (MDD) is well established, but the common use of self-reported measures may limit our understanding of its underlying mechanisms. A promising predictor of patient affect is the stress hormone cortisol. To date, no studies have studied in-session changes in cortisol in psychotherapy for MDD. We investigated whether an increase in patient cortisol over the course of a session correlated with higher negative and lower positive affect. Given previous findings on healthy individuals on the contagious nature of stress, an additional aim was to examine whether these relationships are moderated by therapist cortisol. To this end, 40 dyads (including 6 therapists) provided saliva samples before and after four pre-specified sessions (616 samples). After each session, the patients provided retrospective reports of in-session affect. We found no association between patient cortisol and affect. However, increases in patient cortisol predicted negative affect when the therapists exhibited decreases in cortisol, and increases in patient cortisol predicted positive affect when the therapists showed increases. Our study provides initial evidence for the importance of the social context in the cortisol–affect relationship in MDD.

Author(s):  
Khagendra Nath Gangai ◽  
Rachna Agrawal

Consumer behavior is a complex phenomenon which is evolving according to the time, situations, demographic characteristics of individuals, personality traits, cultural influences etc. The personality of individuals is a unique dynamic organization of the characteristics of a particular person, physical and psychological, which influence behavior and responses to the social and physical environment. It gives the impression that consumer buying is always influenced by their personality. Therefore, many marketers make use of personality traits in the advertisement of products and at the same time they enhance their marketing strategy. The marketers always designed different products and target specific market segments which commonly addressed on individuals personality traits. The individuals few personality traits influence consumer for impulsive buying behavior. The aim of present research is to study the personality traits influence on consumer impulsive buying behavior as it will help to create opportunities of doing business and dealing with customers. The objectives of this research are: (1) to investigate the influence of personality traits on consumer impulsive buying behavior, and (2) to identify the role of gender and their personality traits influence on consumer impulsive buying behavior. To fulfill the purpose of the study, the researchers randomly collected sample and divided them on the basis of gender, 60 males and 60 females. Data were collected from Delhi and NCR region. The data were analyzed using statistical applications such as correlation and t Test. The result was revealed that the common personality traits have a significant relationship with impulsive buying behavior that is psychoticism in the case of male and female. The role of gender has significant differences in impulsive buying behavior. The man showed more impulsive buying behavior compare to women.


2015 ◽  
Vol 8 (12) ◽  
pp. 94 ◽  
Author(s):  
Ahmed Abdulrahman Al-Haramlah ◽  
Fawziah Al-Bakr ◽  
Haniah Merza

<p class="apa">This study aimed to detect the common diseases among Saudi women and their relationship with the level of physical activity and some variables. This study was applied to 1233 Saudi woman in different regions of the Kingdom, and adopted to explore the common diseases: obesity, hypertension, diabetes, cholesterol and asthma.</p><p class="apa">The study results showed the existence of a statistically significant relationship between the common diseases among Saudi women and the variables of educational level, the nature of the profession, the social status, the justification of the practice of physical activity, the rate of participation in physical activity per week, the practice of physical activity in relation to asthma and the number of children with regard to obesity.</p><p class="apa">The study provided a number of recommendations including: the need to strengthen the role of culture in promoting physical activity by women, through health education via the health centers in the Kingdom.</p>


Author(s):  
William Loader

After a brief overview of the social context and role of marriage and sexuality in Jewish and Greco-Roman cultures, the chapter traces the impact of the Genesis creation narratives, positively and negatively, on how marriage and sexuality were seen both in the present and in depictions of hope for the future. Discussion of pre-marital sex, incest, intermarriage, polygyny, divorce, adultery, and passions follows. It then turns to Jesus’ reported response to divorce, arguing that the prohibition sayings should be read as assuming that sexual intercourse both effects permanent union and severs previous unions, thus making divorce after adultery mandatory, the common understanding and legal requirement in both Jewish and Greco-Roman society of the time. It concludes by noting both the positive appreciation of sex and marriage, grounded in belief that they are God’s creation, and the many dire warnings against sexual wrongdoing, including adulterous attitudes and uncontrolled passions.


2018 ◽  
Vol 14 (1) ◽  
pp. 99-109
Author(s):  
Piotr Urbanowicz

Summary In this text, I argue that there are numerous affinities between 19th century messianism and testimonies of UFO sightings, both of which I regarded as forms of secular millennialism. The common denominator for the comparison was Max Weber’s concept of “disenchantment of the world” in the wake of the Industrial Revolution which initiated the era of the dominance of rational thinking and technological progress. However, the period’s counterfactual narratives of enchantment did not repudiate technology as the source of all social and political evil—on the contrary, they variously redefined its function, imagining a possibility of a new world order. In this context, I analysed the social projects put forward by Polish Romantics in the first half of the 19th century, with emphasis on the role of technology as an agent of social change. Similarly, the imaginary technology described by UFO contactees often has a redemptive function and is supposed to bring solution to humanity’s most dangerous problems.


2014 ◽  
Vol 16 (2) ◽  
pp. 171-183 ◽  

Patient reported outcomes (PROs) of quality of life (QoL), functioning, and depressive symptom severity are important in assessing the burden of illness of major depressive disorder (MDD) and to evaluate the impact of treatment. We sought to provide a detailed analysis of PROs before and after treatment of MDD from the large Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. This analysis examines PROs before and after treatment in the second level of STAR*D. The complete data on QoL, functioning, and depressive symptom severity, were analyzed for each STAR*D level 2 treatment. PROs of QoL, functioning, and depressive symptom severity showed substantial impairments after failing a selective serotonin reuptake inhibitor trial using citalopram (level 1). The seven therapeutic options in level 2 had positive statistically (P values) and clinically (Cohen's standardized differences [Cohen's d]) significant impact on QoL, functioning, depressive symptom severity, and reduction in calculated burden of illness. There were no statistically significant differences between the interventions. However, a substantial proportion of patients still suffered from patient-reported QoL and functioning impairment after treatment, an effect that was more pronounced in nonremitters. PROs are crucial in understanding the impact of MDD and in examining the effects of treatment interventions, both in research and clinical settings.


2021 ◽  
Author(s):  
Jane McCamant

Abstract The history of American public education has generally been considered as a steady transition from religious and sectarian to secular and pluralist, with the role of science in education increasing as the role of religion decreased. This article examines a conception of the role of religion in education that does not fit this narrative, the “social religion” of theorists of moral and character education in the 1920s. Relying on ideas of religious naturalism and with an orientation toward the practical effects of religious belief, this community of scholars asserted a concept of religion that would allow it to be at the heart of the common school project, uniting all under the common morality of the social good. Influenced both by liberal Protestant humanism and the scientific worldview pervasive in education reform at the time, these character educationists’ ideas remind us of the historical contingency of categories like “religious” and of the antiquity of ideas we might classify under the heading of spirituality in American culture.


Epigenomics ◽  
2020 ◽  
Vol 12 (19) ◽  
pp. 1725-1738
Author(s):  
Zhifen Liu ◽  
Xinrong Li ◽  
Chen Chen ◽  
Ning Sun ◽  
Yanfang Wang ◽  
...  

Aim: To identify lncRNAs targeting GSK3β in MDD. Materials & methods: The levels of GSK3β and its three targeting lncRNAs (gsk3β antisense AS1, AS2 and AS3) were detected in 52 patients with major depressive disorder (MDD) before and after 8 weeks of escitalopram treatment. The functional study was evaluated using the silence of lncR-gsk3βAS2/3. The correlation between lncRNA-gsk3β and 89 MDD patients was analyzed. Human neuron progenitor cells were used to investigate the functional role of lncRNA-gsk3β in MDD. Results: All three lncRNAs were downregulated in MDD patients but upregulated after treatment. Inhibition of gsk3βAS2/3 reduced GSK3β expression and its phosphorylation levels in the neuron progenitor cells. Conclusion: Our findings suggest that lncRNA-gsk3βAS3 regulates GSK3β activity in MDD and has potential as a novel therapeutic target.


2008 ◽  
Vol 22 (1) ◽  
pp. 55-79 ◽  
Author(s):  
Edward D. Sturman ◽  
Myriam Mongrain

This study sought to test the role of personality within the social rank theory of depression. Specifically, self‐criticism was hypothesised to be a risk factor for mechanisms underlying involuntary subordination, while self‐efficacy was hypothesised to have a protective function. Involuntary subordination has been implicated as an underlying cause of depression and it was therefore important to determine the personality variables and other intrapsychic mechanisms that lead to this condition. The sample consisted of 115 participants (average age of 20.2 years) who were involved in athletic competition. Participants were evaluated at baseline for personality and social rank variables and for mood immediately before and after a competitive match. Two models were tested: the first model showed that self‐criticism and neuroticism predicted a heightened perception of defeat following a loss. Self‐criticism also predicted an inability to accept defeat which was associated with a latent variable interpreted as involuntary subordination. The second model demonstrated that self‐efficacy was associated with a more adaptive response to defeat, being negatively related to the perception of defeat. Both models proved to be viable and suggest that different personality styles confer specific vulnerabilities to involuntary subordination in the context of defeating events. Copyright © 2007 John Wiley & Sons, Ltd.


2004 ◽  
Vol 287 (1) ◽  
pp. R120-R126 ◽  
Author(s):  
Charles C. Horn ◽  
Mark I. Friedman

Anatomic studies show that the common hepatic branch (CHB) of the vagus contains afferent fibers that innervate sites outside the hepatoportal region, primarily in the gastrointestinal tract. In the current experiments on the anesthetized rat, the source of signals from the CHB was determined by recording CHB neurophysiological responses before and after transection of the gastroduodenal branch (GDB) of the CHB. Serotonin [5-hydroxytryptamine (5-HT)] and CCK-8 were used as probes to stimulate the CHB. Most of the CHB afferent fibers were 5-HT sensitive (56%), and 35% of these were also sensitive to CCK-8. Portal vein vs. jugular vein infusion of 5-HT and CCK-8 and GDB transection showed that 5-HT- and CCK-sensitive fibers innervate the hepatoportal region and areas outside the hepatic hilus (e.g., the gastrointestinal tract). Suppression of basal nerve activity by a 5-HT3 receptor antagonist (Y-25130) suggests that ∼50% of CHB afferent fibers contain 5-HT3 receptors, but none of these fibers appears to be in the hepatoportal region because only in rats with an intact GDB did Y-25130 reduce nerve activity. In summary, these data are in close agreement with anatomic observations on the distribution of the CHB fibers and indicate that neurophysiological studies of the CHB must be carefully evaluated given the prominent role of nonhepatoportal afferent signals recorded from the CHB.


2020 ◽  
Vol 2 (2) ◽  
pp. 48-64
Author(s):  
John F. Lingelbach

In light of the wide acknowledgement that humanism influenced the Protestant Reformation, one must ask the question about how much of what Protestantism maintains owes a debt to this modern ideology often juxtaposed in contrast to Christianity. Given the remarkable role of such a controversial ideology during a seminal period of the modern church, this study seeks an answer to the following question: how did the humanism movement of the fourteenth and fifteenth centuries impact the lives and work of the main Magisterial Reformers? This research is important and necessary because discovering the answer to this question leads to an understanding of the larger question of how humanism impacts the Protestant tradition. Understanding the nature of this impact sheds light on what Protestantism means and may induce some Christians to contemplate why they call or do not call themselves “Protestants” or “humanists.” This present study progressed through four phases. First, the study sought to describe the humanism of the fourteenth and fifteenth centuries. Second, it sought to describe the impact this humanism had on society. Third, the study analyzed how the social impacts of the humanism of the fourteenth and fifteenth centuries served to advance or hinder the causes of the main Magisterial Reformers. Finally, it synthesized the findings. This paper argues and concludes that the humanism of the fourteenth and fifteenth centuries impacted the lives and work of the main Magisterial Reformers by facilitating their desire to include the common people in a religious world previously dominated by the elite.


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