scholarly journals Preparation and Antimicrobial Properties of Alginate and Serum Albumin/Glutaraldehyde Hydrogels Impregnated with Silver(I) Ions

Chemistry ◽  
2021 ◽  
Vol 3 (2) ◽  
pp. 672-686
Author(s):  
Louise Gallagher ◽  
Alanna Smith ◽  
Kevin Kavanagh ◽  
Michael Devereux ◽  
John Colleran ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Serum Albumin ◽  
Calcium Alginate ◽  
Metal Ion ◽  
Antimicrobial Properties ◽  
Hydrogel Beads ◽  
Composite Beads ◽  
Antifungal Effects ◽  
Propylene Glycol Alginate ◽  
Antibacterial And Antifungal

Calcium alginate (CaALG) hydrogel beads and two sets of composite beads, formed from a combination of calcium alginate/propylene glycol alginate/human serum albumin (CaALG/PGA/HSA) and from calcium alginate with the quaternary ammonium salt, (3-(trimethoxysilyl)propyl)-octadecyldimethylammonium chloride (QA), (CaALG/QA), were prepared. Bovine serum albumin (BSA) was condensed with glutaraldehyde (GLA) to form a BSA/GLA hydrogel. The corresponding Ag+-containing gels of all of the above hydrogels were also formed, and slow leaching of the biocidal transition metal ion from the gels bestowed broad spectrum antimicrobial activity. In the absence of added Ag+, CaALG/QA was the only material to deliver marginal to moderate antibacterial and antifungal effects. The Ag+ impregnated hydrogel systems have the potential to maintain the antimicrobial properties of silver, minimising the risk of toxicity, and act as reservoirs to afford ongoing sterility.

scholarly journals Antibacterial and antifungal effects of alcoholic extracts of 41 medicinal plants growing in Turkey

2010 ◽  
Vol 28 (No. 1) ◽  
pp. 53-60 ◽  
Author(s):  
Ö. Ertürk
Keyword(s):  
Antimicrobial Activity ◽  
Alnus Glutinosa ◽  
Viscum Album ◽  
Antibacterial And Antifungal Activities ◽  
Galega Officinalis ◽  
Ethanolic Extracts ◽  
Thymus Capitatus ◽  
Antifungal Effects ◽  
Rhus Coriaria ◽  
Antibacterial And Antifungal

The antibacterial and antifungal activities of crude ethanolic extracts of 41 traditional medicinal plant species belonging to 26 families were tested against four bacteria and two fungi: <I>Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans</I>, and <I>Aspergillus niger</I>. Of the 41 plants tested, 39 showed antimicrobial activity against one or more species of microorganisms. While the crude extracts from <I>Nigellea arvensis</I> did not show antimicrobial activity against the test microorganisms, <I>Pistasia lentiscus</I> showed only antifungal activity against A. <I>niger</I>. The most active antimicrobial plants were <I>Cuminum cyminum, Jasminium officinale, Thymus capitatus, Viscum album, Tanecetum sorbifolium, Pimpinella anisum, Galega officinalis, Liguidamber orientalis, Rhus coriaria, Alnus glutinosa, Pimental officinalis, Achillea coarctata</I>, and <I>Cameli sinensis</I>.

scholarly journals In vitro leaves and twigs antimicrobial properties of Psidium guajava L. (Myrtaceae)

2015 ◽  
Vol 61 (3) ◽  
pp. 93-104
Author(s):  
Basel Saleh ◽  
Lila Al-Halab ◽  
Ayman Al-Mariri
Keyword(s):  
Antimicrobial Activity ◽  
Ethyl Acetate ◽  
Inhibitory Concentration ◽  
Activity Index ◽  
Antimicrobial Properties ◽  
Psidium Guajava ◽  
Hot Water ◽  
Antibacterial And Antifungal ◽  
Diffusion Assay

Summary The current study aimed to investigate antimicrobial activity of methanol, ethanol, acetone, ethyl acetate and hot water (leaves and twigs fractions) Psidium guajava L. crude extracts against three bacteria and two fungi pathogens. Antimicrobial activity expressed by disc-diffusion assay (zone of inhibitions - ZIs), activity index (AI) and minimum inhibitory concentration (MICs) that were measured as reported in many investigations. Based upon the estimated ZIs, AI and MICs values, hot water twigs <1 cm diameter extract was the most potent against all tested microorganisms. The MICs value ranged between 4 and 7.2 mg/ml for bacteria, while, it was between 14.5 and 37.3 mg/ml for fungi. Moreover, ethyl acetate had the lowest antimicrobial activity compared to the other tested solvents. From the results obtained herein, it could be concluded that P. guajava serve as antibacterial and antifungal agent.

scholarly journals SYNTHESIS, CHARACTERIZATION, AND ASSESSMENT OF THE ANTIMICROBIAL ACTIVITY OF MGO – CALCIUM ALGINATE POROUS BEADS

2017 ◽  
Vol 26 (2) ◽  
pp. 7
Author(s):  
Oscar Perales Pérez ◽  
Yarilyn CedeñoMattei
Keyword(s):  
Antimicrobial Activity ◽  
Calcium Alginate ◽  
Antimicrobial Agents ◽  
Physical Stability ◽  
Antimicrobial Properties ◽  
Volume Ratio ◽  
Food Preservation ◽  
Polymeric Matrix ◽  
E Coli ◽  
Porous Beads

La dispersión de nanopartículas antibacterianas en matrices poliméricas biocompatibles, no tóxicas y biodegradables permitirá el desarrollo de materiales más eficientes y efectivos para la conservación de alimentos, la eliminación de contaminantes y la protección contra microorganismos que comprometen la salud humana. Los materiales bactericidas nanométricos tienen una relación superficie / volumen muy grande que les permite interactuar con más copias de moléculas biológicas, y por lo tanto, mejorar la eficacia antimicrobiana. Más recientemente, se ha sugerido la actividad antimicrobiana del MgO amigable con el medio ambiente y químicamente estable. La incorporación de compuestos bactericidas en una matriz polimérica puede combinar la estabilidad física proporcionada por la matriz polimérica con las propiedades antimicrobianas de los agentes antimicrobianos dispersados como partıculas pequeñas sólidas. Sobre esta base, la presente investigación se centrará en el desarrollo de mezclas de partículas inorgánicas poliméricas biocompatibles, los denominados nanocompuestos, con actividad antimicrobiana sintonizable y mejorada. Se confirmó la actividad antimicrobiana de perlas de alginato cálcico - MgO (que oscilaban entre 0% y 40% p / p MgO) contra E. coli. Las perlas que contenían 20% p / p de MgO inhibían completamente el crecimiento bacterial de la E. coli. Palabras clave.-Alginato de calcio, Cuentas porosas, Óxido de magnesio, Actividad antimicrobiana. ABSTRACTThe dispersion of antibacterial nanoparticles into bio-compatible, non-toxic and bio-degradable polymeric matrices will enable the development of more efficient and effective materials for food preservation, removal of contaminants, and protection against human health-compromising microorganisms. Nanometric bactericidal materials have a very large surface to volume ratio that enable them to attach more copies of biological molecules, and hence, enhance antimicrobial efficiency. More recently, the antimicrobial activity of environmental-friendly and chemically stable MgO has been suggested. The incorporation of bactericidal compounds into a polymeric matrix can combine physical stability provided by the polymeric matrix with the antimicrobial properties of antimicrobial agents dispersed as solid tiny particles. On this basis, the present research will be focused on the development of biocompatible polymer-inorganic particle mixtures, so-called nanocomposites, with tunable and enhanced antimicrobial activity. The antimicrobial activity of calcium alginate – MgO beads (ranging from 0% - 40% w/w MgO) against E. coli was confirmed. Beads containing 20% w/w of MgO fully inhibited the E. coli. bacterial growth.. Keywords.- Calcium alginate, Porous beads, Magnesium oxide, Antimicrobial activity.

scholarly journals Antimicrobial Activities and Time-Kill Kinetics of Extracts of Selected Ghanaian Mushrooms

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Theresa Appiah ◽  
Yaw Duah Boakye ◽  
Christian Agyare
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agents ◽  
Schizophyllum Commune ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Methanol Extracts ◽  
Test Organisms ◽  
Antibacterial And Antifungal ◽  
Time Kill ◽  
Kinetics Of

The rapid rise of antimicrobial resistance is a worldwide problem. This has necessitated the need to search for new antimicrobial agents. Mushrooms are rich sources of potential antimicrobial agents. This study investigated the antimicrobial properties of methanol extracts of Trametes gibbosa, Trametes elegans, Schizophyllum commune, and Volvariella volvacea. Agar well diffusion, broth microdilution, and time-kill kinetic assays were used to determine the antimicrobial activity of the extracts against selected test organisms. Preliminary mycochemical screening revealed the presence of tannins, flavonoids, triterpenoids, anthraquinones, and alkaloids in the extracts. Methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea showed mean zone of growth inhibition of 10.00±0.0 to 21.50±0.84, 10.00±0.0 to 22.00±1.10, 9.00±0.63 to 21.83±1.17, and 12.00±0.0 to 21.17±1.00 mm, respectively. The minimum inhibitory concentration of methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea ranged from 4.0 to 20, 6.0 to 30.0, 8.0 to 10.0, and 6.0 to 20.0 mg/mL, respectively. Time-kill kinetics studies showed that the extracts possess bacteriostatic action. Methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea exhibited antimicrobial activity and may contain bioactive compounds which may serve as potential antibacterial and antifungal agents.

scholarly journals Antimicrobial Nanoparticles Incorporated in Edible Coatings and Films for the Preservation of Fruits and Vegetables

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1695 ◽  
Author(s):  
Yage Xing ◽  
Wenxiu Li ◽  
Qin Wang ◽  
Xuanlin Li ◽  
Qinglian Xu ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Metal Ion ◽  
Fruits And Vegetables ◽  
Antimicrobial Properties ◽  
Edible Coatings ◽  
Coating Materials ◽  
Antimicrobial Nanoparticles ◽  
Vegetables And Fruits ◽  
Free Metal

Edible coatings and films (ECF) are employed as matrixes for incorporating antimicrobial nanoparticles (NPs), and then they are applied on the fruits and vegetables to prolong shelf life and enhance storage quality. This paper provides a comprehensive review on the preparation, antimicrobial properties and mechanisms, surface and physical qualities of ECF containing antimicrobial NPs, and its efficient application to vegetables and fruits as well. Following an introduction on the properties of the main edible coating materials, the preparation technologies of ECF with NPs are summarized. The antimicrobial activity of ECF with NPs against the tested microorganism was observed by many researchers. This might be mainly due to the electrostatic interaction between the cationic polymer or free metal ions and the charged cell membrane, the photocatalytic reaction of NPs, the detachment of free metal ion, and partly due to the antimicrobial activity of edible materials. Moreover, their physical, mechanical and releasing properties are discussed in detail, which might be influenced by the concentration of NPs. The preservation potential on the quality of fruits and vegetables indicates that various ECF with NPs might be used as the ideal materials for food application. Following the introduction on these characteristics, an attempt is made to predict future trends in this field.

scholarly journals Antimicrobial Activities of Chitosan Derivatives

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1639
Author(s):  
Cristina Ardean ◽  
Corneliu Mircea Davidescu ◽  
Nicoleta Sorina Nemeş ◽  
Adina Negrea ◽  
Mihaela Ciopec ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Activities ◽  
Culture Collection ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
New Materials ◽  
Direct Control ◽  
Antifungal Effects ◽  
Antibacterial And Antifungal ◽  
Reference Strains

Considering the challenge created by the development of bacterial and fungal strains resistant to multiple therapeutic variants, new molecules and materials with specific properties against these microorganisms can be synthesized, like those synthesized from biopolymers such as chitosan with improved antimicrobial activities. Antimicrobial activities of seven obtained materials were tested on four reference strains belonging to American Type Culture Collection. The best antimicrobial activity was obtained by functionalization by impregnation of chitosan with quaternary ammonium salts, followed by that obtained by functionalization of chitosan with phosphonium. The lowest antibacterial and antifungal effects were expressed by Ch-THIO and Ch-MBT, but new materials obtained with these extractants may be precursors with a significant role in the direct control of active molecules, such as cell growth factors or cell signaling molecules.

scholarly journals Screening of antibacterial and antifungal activities of selected Macedonian wild mushrooms

2013 ◽  
pp. 333-340 ◽  
Author(s):  
Daniela Nikolovska-Nedelkoska ◽  
Natalija Atanasova-Pancevska ◽  
Haris Amedi ◽  
Dafina Veleska ◽  
Emilija Ivanova ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Inhibitory Concentration ◽  
Methanolic Extract ◽  
Antimicrobial Properties ◽  
Inhibitory Effects ◽  
Antibacterial And Antifungal Activities ◽  
Microdilution Method ◽  
Methanolic Extracts ◽  
Antibacterial And Antifungal

Regarding the development of novel safe antimicrobials of natural origin, macrofungi became attractive for the researchers in the last decade. In this study, antimicrobial potential of methanolic extracts of six wild macromycetes (Boletus lupinus, Flammulina velutypes, Phellinus igniarius, Sarcodon imbricatus, Tricholoma aurantium, Xerocomus ichnusanus) was evaluated. In vitro antimicrobial activity was investigated by the microdilution method and minimum inhibitory concentration (MIC) was determined. Testing was conducted against eleven microorganisms, including six strains of bacteria and five species of fungi. Extracts showed selective antimicrobial properties while the activities depended both on the species of microorganism and on the type and concentration of extract. The evaluated extracts demonstrated antimicrobial activity, exhibiting more potent inhibitory effects on the growth of bacteria than on fungi. The highest antibacterial and antifungal activity was observed in methanolic extract of polypore fungus P. igniarius.

scholarly journals Review of Antimicrobial Studies of Ethnomedicinal Plants Used in Skin Treatment by Korkus of Melghat Dist. Amravati (MS), India.

2018 ◽  
Vol 1 (03) ◽  
pp. 61-72
Author(s):  
V D Devarkar ◽  
P Y Bhogaonkar
Keyword(s):  
Antimicrobial Activity ◽  
Plant Species ◽  
Antimicrobial Properties ◽  
Traditional Treatment ◽  
Ethnomedicinal Plants ◽  
Antifungal Properties ◽  
Antimicrobial Studies ◽  
Ethnomedicinal Plant ◽  
Antibacterial And Antifungal ◽  
Available Information

Ethnobotanical investigations in Melghat revealed 180 ethnomedicinal plant species out of which 21 are used by Korkus for various skin related problems. These plants are also reviewed for their antimicrobial properties recorded in the literature. Out of 21 plants selected for study 20 species belong to Dicots and only 01 belongs to Monocot. While reviewing the literature it is observed that, Ten (10) species were exhaustively studied for their antibacterial and antifungal properties, Six (6) species have been studied for either antibacterial or antifungal properties, however five (5) species have not been analyzed for their antimicrobial properties. All the ethnomedicinal plants studied for their antimicrobial properties show significant antimicrobial activity which supports traditional treatment system. The paper deals with ethnomedicinal information along with available information on antimicrobial studies. 

scholarly journals Study of the Biological Activity of Alkyl Derivatives of Tetrahydroisoquinolines

2021 ◽  
pp. 238-246
Author(s):  
Umida Khamidova ◽  
Ekaterina Terenteva ◽  
Mukaddas Umarova ◽  
Jaloliddin Abdurakhmanov ◽  
Sabirdjan Sasmakov ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Biological Activity ◽  
Cancer Cells ◽  
Cytotoxic Effect ◽  
Normal Cells ◽  
Alkyl Derivatives ◽  
Antifungal Effects ◽  
Low Toxicity ◽  
Antibacterial And Antifungal ◽  
Derivatives Of

A row of 1-alkyne (C6-C17) derivatives against tetrahydroisoquinoline have been synthesized. 1-alkyne (C6-C17) derivatives cytotoxicity against three lines of cancer cells and two lines of normal cells was studied. It was found that 1-tridecyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline exhibits a high cytotoxic effect with low toxicity to healthy cells. Antimicrobial activity of 1-alkyne (C6-C17) derivatives against 5 strains of bacteria and fungus was studied. It has been found that 1-nonyl-6,7-dimethoxy-1,3,4-tetrahydroisoquinoline exhibits strong antibacterial and antifungal effects.

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