scholarly journals Feasibility of Race by Sex Intersectionality Research on Suicidality in the Adolescent Brain Cognitive Development (ABCD) Study

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 437
Author(s):  
Shervin Assari ◽  
Shanika Boyce ◽  
Mohsen Bazargan
Keyword(s):  
Cognitive Development ◽  
Sample Size ◽  
Child Behavior Checklist ◽  
Reliability And Validity ◽  
Self Report ◽  
Large Sample Size ◽  
Cross Sectional ◽  
Cronbach Alpha ◽  
Rich Data ◽  
Suicidal Ideas

Intersectional research on childhood suicidality requires studies with a reliable and valid measure of suicidality, as well as a large sample size that shows some variability of suicidality across sex by race intersectional groups. Objectives: We aimed to investigate the feasibility of intersectionality research on childhood suicidality in the Adolescent Brain Cognitive Development (ABCD) study. We specifically explored the reliability and validity of the measure, sample size, and variability of suicidality across sex by race intersectional groups. Methods: We used cross-sectional data (wave 1) from the ABCD study, which sampled 9013 non-Hispanic white (NHW) or non-Hispanic black (NHB) children between the ages of 9 and 10 between years 2016 and 2018. Four intersectional groups were built based on race and sex: NHW males (n = 3554), NHW females (n = 3158), NHB males (n = 1164), and NHB females (n = 1137). Outcome measure was the count of suicidality symptoms, reflecting all positive history and symptoms of suicidal ideas, plans, and attempts. To validate our measure, we tested the correlation between our suicidality measure and depression and Child Behavior Checklist (CBCL) sub-scores. Cronbach alpha was calculated for reliability across each intersectional group. We also compared groups for suicidality. Results: We observed some suicidality history in observed 3.2% (n = 101) of NHW females, 4.9% (n = 175) of NHW males, 5.4% (n = 61) of NHB females, and 5.8% (n = 68) of NHB males. Our measure’s reliability was acceptable in all race by sex groups (Cronbach alpha higher than .70+ in all intersectional groups). Our measure was valid in all intersectional groups, documented by a positive correlation with depression and CBCL sub-scores. We could successfully model suicidality across sex by race groups, using multivariable models. Conclusion: Given the high sample size, reliability, and validity of the suicidality measure, variability of suicidality, it is feasible to investigate correlates of suicidality across race by sex intersections in the ABCD study. We also found evidence of higher suicidality in NHB than NHW children in the ABCD study. The ABCD rich data in domains of social context, self-report, schools, parenting, psychopathology, personality, and brain imaging provides a unique opportunity to study intersectional differences in neural circuits associated with youth suicidality.

scholarly journals Development and validation of continuity measures for inpatients receiving rehabilitation care

2018 ◽  
Vol 7 (4) ◽  
pp. 1
Author(s):  
Silvana L. Oliveira Sousa ◽  
Francesc Medina-Mirapeix ◽  
Pilar Escolar-Reina ◽  
Sean M. Collins ◽  
M. Carmen Lillo-Navarro
Keyword(s):  
Intraclass Correlation ◽  
Reliability And Validity ◽  
Self Report ◽  
Satisfaction Scale ◽  
Cross Sectional ◽  
Rehabilitation Care ◽  
Individual Measure ◽  
Relational Management ◽  
Test Retest Reliability ◽  
Development And Validation

Objective: The main goal of this study was to exemplify the development of a measure of continuity of care (COC) from inpatients’ perspective. This measure is focused on several aspects related to physiotherapy.Methods: A cross-sectional self-report based psychometric study was carried out in a public hospital in southeast Spain. One hundred and fifty two patients with neurological and orthopaedic disorders who received rehabilitation care during stay at hospital were included in the study. A self-report questionnaire was used to examine experiences of patients related to the three types of COC, relational, management and informational continuity. The questionnaire also includes questions about sociodemographic characteristics, patient/therapist affiliation and trust with therapist. To examine reliability were used test-retest and internal consistency. For validation analysis, there were used convergent and known group strategies.Results: Of the 19 indicators included, 13 were selected to demonstrate adequate reliability and validity. From these indicators were generated three composite measures (Relational, management and COC index) and one individual measure (Informational continuity). Test-retest reliability indicated excellent agreement (intraclass correlation coefficient [ICC] > 0.75) for the three indexes. The range of Cronbach’s value was from 0.60 to 0.73. Total scores of all the indexes were moderately correlated with the satisfaction scale (r > 0.30). Regarding the known groups, all indexes scores were similar for men and woman. However, significant differences were found for management index and for relational index, based on trust with therapist and patient/therapist affiliation, respectively.Conclusions: The continuity self-reported measures is a valid and reliable method to assessing the COC in hospitalized patients receiving physiotherapy.

scholarly journals CYTOCHROME P450 CYP1B1*2 GENE AND ITS ASSOCIATION WITH T2D IN TABUK POPULATION, NORTHWESTERN REGION OF SAUDI ARABIA

2018 ◽  
Vol 11 (1) ◽  
pp. 55
Author(s):  
Imadeldin Elfaki ◽  
Fahad M Almutairi ◽  
Rashid Mir ◽  
Roaid Khan ◽  
Faisel Abu-duhier
Keyword(s):  
Cytochrome P450 ◽  
Sample Size ◽  
Cross Sectional Study ◽  
Fisher Exact Test ◽  
Large Sample Size ◽  
Genotype Distribution ◽  
Chi Square ◽  
Cross Sectional ◽  
Exact Test ◽  
Northwestern Region

Objective: Cytochrome P450 1B1 (CYP1B1) is involved in the activation of procarcinogens and steroid metabolism. Genetic variants of CYP1B1are associated with altered catalytic activity and disease phenotypes. The purpose of this study was to investigate the role of CYP1B1 (rs1056827) polymorphism in inducing T2D.Methods: This cross-sectional study enrolled 113 subjects of T2D and 120 controls. DNA was isolated from blood. Genotyping of the rs1056827 wasdone by allele-specific polymerase chain reaction. The frequency of alleles and genotype distribution was compared in T2D cases and healthy controls.Statistical analysis was performed with SPSS, Chi-square, and Fisher exact test. Hardy-Weinberg equilibrium was tested by a χ2 test. The associations between rs1056827 variant genotypes and T2D were estimated by computing the odds ratios and their 95% confidence intervals (CI) from univariate and multivariate logistic regression analysis.Results: A significant association of rs1056827 was found between T2D cases and controls (p<0.0001). When GG genotype was compared with GT genotype a significant association was found with odd ration (OD)0.24 (95% CI: (0.131–0.452) and risk ratio (RR) 0.45 (0.30–0.67) times the risk of T2D heterozygous with the G/T allele (p≤0.0002). In a comparison of GG homozygous with the TT homozygous, there was no significant association with the OD 0.38 (95% CI: (0.02–6.51) RR 0.55(0.13–2.35), p<0.49. When G allele was compared with the T allele a highly significant association with OD 0.54 (95% [CI]: (0.37–0.80) RR 0.75(0.630–0.897) < p≤0.003 suggesting a possible dominant effect of this polymorphism on T2D risk.Conclusion: This result suggests a significant association between rs1056827G>T polymorphism and T2D. This finding is limited due to the smaller sample size and can be validated by large sample size studies.

scholarly journals Inpatient Satisfaction and Effecting Factors: Findings from a Large Sample Size Cross Sectional Study

2016 ◽  
Vol 1 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Mohammad Gholami Fesharaki ◽  
Hesam Akbari ◽  
Hamed Akbari ◽  
Masome Mohammadian
Keyword(s):  
Sample Size ◽  
Cross Sectional Study ◽  
Large Sample Size ◽  
Sectional Study ◽  
Cross Sectional ◽  
Large Sample

scholarly journals Comparison of the University of California–Los Angeles Shoulder Scale and the Simple Shoulder Test With the Shoulder Pain and Disability Index: Single-Administration Reliability and Validity

2000 ◽  
Vol 80 (8) ◽  
pp. 759-768 ◽  
Author(s):  
Toni S Roddey ◽  
Sharon L Olson ◽  
Karon F Cook ◽  
Gary M Gartsman ◽  
William Hanten
Keyword(s):  
Factor Analysis ◽  
Los Angeles ◽  
Shoulder Pain ◽  
Reliability And Validity ◽  
Factor Loading ◽  
Self Report ◽  
University Of California ◽  
Simple Shoulder Test ◽  
Cronbach Alpha ◽  
The University

Abstract Background and Purpose. Shoulder scales are often used to evaluate treatment efficacy, yet little is known about the psychometric properties of these scales. Only one scale has undergone psychometric scrutiny: the Shoulder Pain and Disability Index (SPADI). This study compared 2 shoulder measures—the University of California-Los Angeles (UCLA) Shoulder Scale and the Simple Shoulder Test (SST)—with the SPADI. Subjects. One hundred ninety-two patients with shoulder disorders were recruited from one physician's office to complete the self-report sections of the 3 scales. Methods. Cronbach alpha values and standard errors of measurement (SEM) were calculated for each of the multi-item subscales. Validity was examined through calculation of correlation coefficients among the 3 scales. Factor analysis was completed to assess the underlying constructs of the SPADI and the SST. Results. Cronbach alpha values ranged from .85 to .95. The SEM values for the multi-item scales ranged from 4.75 to 11.65. Evidence for validity to reflect function was indicated by the correlation between the SST and the SPADI disability subscale. The factor analysis of the SPADI revealed loading on 1 factor, whereas the SST loaded on 2 factors. Conclusion and Discussion. All scales demonstrated good internal consistency, suggesting that all items for each scale measure the same construct. However, the SEMs for all scales were high. Factor loading was inconsistent, suggesting that patients may not distinguish between pain and function.

scholarly journals Severe physical punishment and mental health problems in an economically disadvantaged population of children and adolescents

2006 ◽  
Vol 28 (4) ◽  
pp. 290-296 ◽  
Author(s):  
Isabel Altenfelder Santos Bordin ◽  
Cristiane Silvestre Paula ◽  
Rosimeire do Nascimento ◽  
Cristiane Seixas Duarte
Keyword(s):  
Mental Health ◽  
Low Income ◽  
Child Behavior Checklist ◽  
Mental Health Problems ◽  
Adolescent Mental Health ◽  
Health Problems ◽  
Physical Punishment ◽  
Marital Violence ◽  
Self Report ◽  
Cross Sectional

OBJECTIVE: To estimate the prevalence of severe physical punishment of children/adolescents in a low-income community, and to examine child mental health problems as a potential correlate. METHOD: This study is a Brazilian cross-sectional pilot study of the World Studies of Abuse in Family Environments. A probabilistic sample of clusters including all eligible households (women aged 15-49 years, son/daughter < 18 years) was evaluated. One mother-child pair was randomly selected per household (n = 89; attrition = 11%). Outcome (severe physical punishment of children/adolescents by mother/father) was defined as shaking (if age < 2 years), kicking, choking, smothering, burning/scalding/branding, beating, or threatening with weapon. Three groups of potential correlates were examined: child/adolescent (age, gender, physical/mental health); mother (education, unemployment, physical/mental health, harsh physical punishment in childhood, marital violence); father (unemployment, drunkenness). Severe marital violence was defined as kicking, hitting, beating or use of /threat to use a weapon. The following standardized questionnaires were applied by trained interviewers: World Studies of Abuse in Family Environments Core Questionnaire, Child Behavior Checklist, Self-Report Questionnaire. RESULTS: Outcome prevalence was 10.1%. Final logistic regression models identified two correlates: maternal harsh physical punishment in childhood (total sample, OR = 5.3, p = 0.047), and child/adolescent mental health problems (sub-sample aged 4-17 years, n = 67, OR = 9.1, p = 0.017). CONCLUSIONS: Severe physical punishment of children/adolescents is frequent in the studied community. The victims have a higher probability of becoming future perpetrators. When intrafamilial violence occurs, child/adolescent mental health may be compromised.

scholarly journals Measuring Perceived Barriers to Physical Activity in Adolescents

2015 ◽  
Vol 27 (2) ◽  
pp. 252-261 ◽  
Author(s):  
Katie E. Gunnell ◽  
Jennifer Brunet ◽  
Erin K. Wing ◽  
Mathieu Bélanger
Keyword(s):  
Physical Activity ◽  
Vigorous Physical Activity ◽  
Reliability And Validity ◽  
Perceived Barriers ◽  
Self Report ◽  
Cross Sectional ◽  
Confirmatory Factor Analyses ◽  
Group Sex ◽  
The Impact ◽  
Composite Reliability

Background:Perceived barriers to moderate-to-vigorous physical activity (PA) may contribute to the low rates of moderate-to-vigorous PA in adolescents. We examined the psychometric properties of scores from the perceived barriers to moderate-to-vigorous PA scale (PB-MVPA) by examining composite reliability and validity evidence based on the internal structure of the PB-MVPA and relations with other variables.Methods:This study was a cross-sectional analysis of data collected in 2013 from adolescents (N = 507; Mage = 12.40, SD = .62) via self-report scales.Results:Using exploratory and confirmatory factor analyses, we found that perceived barriers were best represented as two factors representing internal (e.g., “I am not interested in physical activity”) and external (e.g., “I need equipment I don’t have”) dimensions. Composite reliability was over .80. Using multiple regression to examine the relationship between perceived barriers and moderate-to-vigorous PA, we found that perceived internal barriers were inversely related to moderate-to-vigorous PA (β = -.32, p < .05). Based on results of the analysis of variances, there were no known-group sex differences for perceived internal and external barriers (p < .26).Conclusions:The PB-MVPA scale demonstrated evidence of score reliability and validity. To improve the understanding of the impact of perceived barriers on moderate-to-vigorous PA in adolescents, researchers should examine internal and external barriers separately.

scholarly journals Reconstructing heterogeneous pathogen interactions from co-occurrence data via statistical network inference

2021 ◽  
Author(s):  
Irene Man ◽  
Elisa Benincà ◽  
Mirjam E Kretzschmar ◽  
Johannes A Bogaards
Keyword(s):  
Sample Size ◽  
Network Inference ◽  
Network Models ◽  
Population Level ◽  
Unbiased Estimation ◽  
Large Sample Size ◽  
Cross Sectional ◽  
Individual Level ◽  
Heterogeneous Interaction ◽  
Pathogen Strains

Infectious diseases often involve multiple pathogen species or multiple strains of the same pathogen. As such, knowledge of how different pathogen species or pathogen strains interact is key to understand and predict the outcome of interventions that target only a single pathogen or subset of strains involved in disease. While population-level data have been used to infer pathogen strain interactions, most previously used inference methods only consider uniform interactions between all strains, or focus on marginal interactions between pairs of strains (without correction for indirect interactions through other strains). Here, we evaluate whether statistical network inference could be useful for reconstructing heterogeneous interaction networks from cross-sectional surveys tracking co-occurrence of multi-strain pathogens. To this end, we applied a suite of network models to data simulating endemic infection states of pathogen strains. Satisfactory performance was demonstrated by unbiased estimation of interaction parameters for large sample size. Accurate reconstruction of networks may require regularization or penalizing for sample size. Of note, performance deteriorated in the presence of host heterogeneity, but this could be overcome by correcting for individual-level risk factors. Our work demonstrates how statistical network inference could prove useful for detecting pathogen interactions and may have implications beyond epidemiology.

scholarly journals LEVEL OF SATISFACTION WITH COVID-19 VACCINE AFTER GETTING JABS AMONG THE GENERALPOPULATION IN GURGAON, HARYANA

2021 ◽  
Vol 9 (10) ◽  
pp. 750-756
Author(s):  
Gyan Jyoti ◽  
◽  
Arun Kumar Yadav ◽  
Ritu Kumari ◽  
Ruma Coudhary Bhattacharjee ◽  
...  
Keyword(s):  
Infectious Disease ◽  
General Population ◽  
Severe Acute Respiratory Syndrome ◽  
Sample Size ◽  
High Rate ◽  
Large Sample Size ◽  
Cross Sectional ◽  
High Burden ◽  
Effective Interventions ◽  
Level Of Satisfaction

Coronavirus disease (COVID-19) is an infectious disease caused Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).To bring this pandemic to an end, only Vaccines are effective interventions that can reduce the high burden of this diseases globally.The purpose of the study to assess the level of satisfaction among the general population after getting the jab of covid -19 vaccine and regarding the vaccination services. A quantitative approach, cross sectional e- survey was conducted on 332 general population through snow ball sampling among general population of Gurgaonaged 18 years and above from 25th May 2021 to 30th July 2021. The result showed that 70.8% of general populationwere dissatisfied after getting the jab of COVID 19 vaccine. The results indicate a high rate of dissatisfaction after getting jab of the COVID-19 vaccine among general population. This result may vary with large sample size.

Psychometric Properties of Three Medication Adherence Scales in Patients With Rheumatoid Arthritis

2012 ◽  
Vol 20 (1) ◽  
pp. 59-72 ◽  
Author(s):  
Elizabeth Salt ◽  
Lynne Hall ◽  
Ann R. Peden ◽  
Rob Horne
Keyword(s):  
Rheumatoid Arthritis ◽  
Medication Adherence ◽  
Psychometric Properties ◽  
Patient Adherence ◽  
Reliability And Validity ◽  
Cross Sectional Study ◽  
Self Report ◽  
Cross Sectional ◽  
Two Factors ◽  
Adherence Scale

Patient adherence to their health care protocols is important to encourage the best health outcomes in rheumatoid arthritis (RA); however, little attention has been given to assessing the psychometric properties of adherence measures in this patient population. The purpose of this study was to evaluate the psychometric properties of three existing self-report measures of medication adherence in a sample of patients with RA—the Compliance-Questionnaire-Rheumatology (CQR), the Medication Adherence Report Scale (MARS), and the Medication Adherence Scale (MAS). A cross-sectional study of 108 clinic patients with rheumatoid arthritis was conducted to evaluate the reliability and validity of the measures. Cronbach’s alpha was .77 for both the CQR and a modified version of the MARS. For the MAS, the Kuder-Richardson 20 reliability was .25. Although not strong, test-retest reliability was adequate for all measures. Factor analysis indicated that both the MARS and the CQR measure two factors. All three instruments were moderately correlated with each other, with correlations ranging between .48 and .56. Although these scales were significantly correlated, moderate correlations among the scales indicate that they may not measure the same aspects of adherence. Among the three adherence measures, the modified MARS demonstrated the best evidence of reliability and validity and ease of administration in this sample of persons with RA.

Posttraumatic stress disorder checklist military version in latvian language

2011 ◽  
Vol 26 (S2) ◽  
pp. 1088-1088 ◽  
Author(s):  
V. Voicehovskis ◽  
G. Ancane ◽  
J. Voicehovska ◽  
L. Umnova ◽  
A. Skesters
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Reliability And Validity ◽  
Self Report ◽  
Service Members ◽  
Cronbach Alpha ◽  
Language Version ◽  
Response Sets ◽  
Active Service

IntroductionThe Posttraumatic Stress Disorder (PTSD) Checklist (PCL) is a 17-item self-report measure of the 17 DSM-IV symptoms of PTSD. The PCL has a variety of purposes, including screening individuals for PTSD, diagnosing PTSD, monitoring symptom change during and after treatment. There are three versions of the PCL: PCL-C (civilian), PCL-M (military) and PCL-S (specific). PCL-M asks about symptoms in response to “stressful military experiences” and used for active service members and veterans. The PCL-M can be completed by participants of a research study in approximately 5–10 minutes. Interpretation of the PCL-M should be completed by a clinician. There is no valid PCL-M Latvian language version.AimsThe goal of the study is to assess the evaluative and discriminative properties of the Latvian language version of the PCL-M in PTSD risk group patients (PTSD-RGP).MethodsTotally 30 participants (males, Europeans, of average age 26.2, PTSD-RGP - Latvian Contingent of International Operations) were examined. Standart validation protocol was applied for PCL-M Latvian language version's reliability and validity testing: reliability consequence, construct validity, test-retest, Cronbach alpha criterion.ResultsCronbach alpha criterion was more than 0,70 (means reliable response sets), the reliability-consequence scale is from 0.6 to 0.9 (means precise definition). Test-retest by Spearman showed r ≥ 0.75 (means reliable stability).ConclusionsIt was concluded that the PLC-M Latvian language version has sufficiently acceptable evaluative and discriminatory properties and is therefore a valid instrument for PTSD measurements in clinical and research studies in Latvian military active service members and veterans.

Sign in / Sign up

Export Citation Format

Share Document