Reasons for Tooth Extractions and Related Risk Factors in Adult Patients: A Cohort Study

Background: The aim of this study was to evaluate oral status, the reasons for tooth extractions and related risk factors in adult patients attending a hospital dental practice. Methods: 120 consecutive patients ranging from 23 to 91 years in age (mean age of 63.3 ± 15.8) having a total of 554 teeth extracted were included. Surveys about general health status were conducted and potential risk factors such as smoking, diabetes and age were investigated. Results: a total of 1795 teeth were missing after extraction procedures and the mean number of remaining teeth after the extraction process was 16.8 ± 9.1 per patient. Caries (52.2%) was the most common reason for extraction along with periodontal disease (35.7%). Males were more prone to extractions, with 394 of the teeth extracted out of the total of 554 (71.1%). Male sex (β = 2.89; 95% CI 1.26, 4.53; p = 0.001) and smoking habit (β = 2.95; 95% CI 1.12, 4.79; p = 0.002) were related to a higher number of teeth extracted. Age (β = −0.24; 95% CI −0.31, −0.16; p < 0.001) and diabetes (β = −4.47; 95% CI −7.61, −1.33; p = 0.006) were related to a higher number of missing teeth at evaluation time. Moreover, periodontal disease was more common as a reason of extraction among diabetic patients than among non-diabetic ones (p = 0.04). Conclusions: caries and periodontal disease were the most common causes of extraction in a relatively old study population: further screening strategies might be required for the early interception of caries and periodontal disease.

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Correlation between Potential Risk Factors and Pulmonary Embolism in Sarcoidosis Patients Timely Treated

Journal of Clinical Medicine ◽

10.3390/jcm10112462 ◽

2021 ◽

Vol 10 (11) ◽

pp. 2462

Author(s):

Barbara Ruaro ◽

Paola Confalonieri ◽

Mario Santagiuliana ◽

Barbara Wade ◽

Elisa Baratella ◽

...

Keyword(s):

Risk Factors ◽

Pulmonary Embolism ◽

Potential Risk ◽

Smoking Habit ◽

Age At Diagnosis ◽

Antiphospholipid Antibody ◽

Increased Risk ◽

Significant Difference ◽

Antibody Positivity ◽

Potential Risk Factors

Background. Some studies with inconclusive results have reported a link between sarcoidosis and an increased risk of pulmonary embolism (PE). This study aimed at assessing a possible correlation between potential risk factors and PE in sarcoidosis patients. Methods. A total of 256 sarcoidosis patients (84 males and 172 females; mean age at diagnosis 49 ± 13) were enrolled after giving written informed consent. Clinical evaluations, laboratory and radiology tests were performed to evaluate the presence of pulmonary embolism. Results. Fifteen sarcoidosis patients with PE (4 males and 11 females; mean age at diagnosis 50 ± 11), diagnosed by lung scintigraphy and 241 sarcoidosis patients without PE (80 males and 161 females; mean age at diagnosis 47 ± 13), were observed. There was a statistically significant increase of the presence of antiphospholipid antibodies in the sarcoidosis group with pulmonary embolism. There was no statistically significant difference between the two groups as to smoking habit, obesity or hereditary thrombophilia frequency (p > 0.05, respectively). Conclusions. This study demonstrates a significant correlation between the presence of antiphospholipid antibody positivity and the pulmonary embolism events in our sarcoidosis patients. Furthermore, we propose screening for these antibodies and monitoring, aimed at timely treatment.

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Evaluation of the Potential Risk Factors for Drug-Induced Anaphylaxis in Adult Patients

International Archives of Allergy and Immunology ◽

10.1159/000494130 ◽

2018 ◽

Vol 178 (2) ◽

pp. 167-176 ◽

Cited By ~ 4

Author(s):

Semra Demir ◽

Fusun Erdenen ◽

Asli Gelincik ◽

Derya Unal ◽

Muge Olgac ◽

...

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Adult Patients ◽

Drug Induced ◽

Potential Risk Factors

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Potential risk factors of pneumonitis associated with consolidation pembrolizumab after chemoradiation in unresectable NSCLC patients.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.5_suppl.167 ◽

2018 ◽

Vol 36 (5_suppl) ◽

pp. 167-167

Author(s):

Shahid Sattar Ahmed ◽

Greg Andrew Durm ◽

John Donatelli ◽

Huan Yao ◽

Yongmei Liu ◽

...

Keyword(s):

Risk Factors ◽

Radiation Treatment ◽

Smoking Status ◽

Limited Data ◽

Exact Test ◽

Unresectable Stage ◽

Related Risk ◽

Potential Risk Factors ◽

Ecog Ps ◽

Nsclc Patients

167 Background: We have previously shown that consolidation pembrolizumab after chemoradiation is safe in a 93 patient-clinical trial of unresectable stage III NSCLC patients (Durm, ASCO 2016). However 15 patients (16%) developed grade ≥2 pneumonitis. There is limited data on risk factors for developing pneumonitis in this population. We conducted a retrospective review of these patients to identify potential clinical, biologic, radiographic and radiation treatment related risk factors for developing pneumonitis. Methods: We evaluated ECOG PS, age, gender, smoking status, stage, histology, chemo regimen, consolidation chemotherapy, TILs, PDL-1 status, PFTs, PET SUVs, grade of pre-existing ILD, COPD and Radiation dosimetry plans. Logistic regression and fisher’s-exact test were used for the odds ratio and p-values. Results: See Table. [1] [1] Age, histology, stage, chemo, PFTs, SUVs and PDL1 were not significant [2] n = sample size p = pneumonitis [3] Moderate/severe COPD was not seen in any patients with pneumonitis despite 94% of participants being smokers. Conclusions: This preliminary report highlights the utility of a multi-disciplinary approach to develop risk-stratification models for pneumonitis in an at-risk patient population. However larger prospective studies are needed to validate their meaningful use in the clinical setting.[Table: see text]

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Risk Factors of Cardiovascular Disease in Elderly in Guguak Kabupaten 50 Kota, West Sumatera, Indonesia

Human Care Journal ◽

10.32883/hcj.v5i1.650 ◽

2020 ◽

Vol 5 (1) ◽

pp. 348

Author(s):

Debie Anggraini ◽

Prima Adelin

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Disease ◽

Central Obesity ◽

Smoking Habit ◽

The Elderly ◽

Modifiable Risk Factors ◽

Cvd Risk ◽

Related Risk ◽

Low Hdl

Introduction: Cardiovascular disease (CVD) is a major cause of death and disability worldwide. The most stringent primary CVD screening guidelines in developed countries use absolute CVD risk scores or coronary heart disease, such as Framingham or SCORE (Systematic Coronary Risk Evaluation) there are two types of CVD risk factors namely modifiable risk factors and unmodified risk factors. The aim of the current study is to determine the profil of potentially modifiable and unmodified cardiovascular risk factors. Method: This research consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The data taken is modifiable risk factors consisting of diseases related risk factors including blood pressure categories, lipid profile, central obesity, body mass index and lifestyle related risk factors such as smoking habit. We also take data of unmodified risk factors such as age and gender. The result: this study consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The mean age of elderly were 68±7.64861 years old that consisting of 29.3% men and 70.7% women, 34% of elderly with hypertension, the elderly with hypercholesterolemia 71%, hypertriglyceridemia 41%, and the elderly women with low HDL-C levels were 53%, the elderly men with low HDL-C levels were 92%. Conclusion: There are two types of risk factors CVD, modifiable risk factors and nonmodifiable risk factors. The modifiable risk factors consisting of diseases related risk factors including blood pressure categories, lipid profile, central obesity, body mass index and lifestyle related risk factors such as smoking habit.

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Epidemiologic Study of Infant Botulism in Pennsylvania: Report of the Infant Botulism Study Group

PEDIATRICS ◽

10.1542/peds.75.5.928 ◽

1985 ◽

Vol 75 (5) ◽

pp. 928-934

Author(s):

Sarah S. Long

Keyword(s):

Risk Factors ◽

Epidemiologic Study ◽

Geographic Area ◽

The United States ◽

Family Characteristics ◽

Related Factors ◽

Related Risk ◽

Potential Risk Factors ◽

Infant Botulism ◽

Low Prevalence

The majority of the almost 400 confirmed cases of infant botulism in the United States have occurred in California, Pennsylvania, and Utah. In Pennsyvania, 44 of 53 (83%) cases occurred within a geographic area of Southeastern Pennsylvania which represents one tenth of the Commonwealth's area and one third of the population at risk for infant botulism. In Southeastern Pennsylvania, a map of the residences of cases circumscribes a discrete ring around Philadelphia. A case-control study performed to seek host-related risk factors, identifies the significant associations of botulism with infants who are white, breast-fed, and born at term into two-parent families with hospitalization insurance. County control studies were performed to identify differences in host-related factors between areas of high and low prevalence of botulism. Although some "protection" could be afforded Philadelphia infants by their feeding and family characteristics, the differences in case rates between Philadelphia and the botulism "ring counties" cannot be explained entirely by host-related factors. Further, the absence of botulism in counties just outside of the botulism "ring," where infants were found to have identical potential risk factors, suggests that an uneven distribution of botulinal spores in the environment is the most significant determinant of case rate.

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Risk Factors of Composite Attachment Loss During Orthodontic Clear Aligner Therapy

10.21203/rs.3.rs-30277/v1 ◽

2020 ◽

Author(s):

Yaosen Chen ◽

Mohamed AM ◽

WANG Jinbo ◽

ZHENG Ziwei ◽

Maher Al-balaa ◽

...

Keyword(s):

Risk Factors ◽

Daily Practice ◽

Multivariable Logistic Regression Analysis ◽

Chi Square ◽

Attachment Loss ◽

Wear Time ◽

Related Risk ◽

Potential Risk Factors ◽

Chi Square Test ◽

Clear Aligner

Abstract Background The composite attachment loss during orthodontic clear aligner therapy is an adverse event that commonly happens in our daily practice. However, there is a lack of related statistical analysis, and studies analyzing the related risk factors. Therefore, the aim of this study is to assess the incidence of attachment loss during orthodontic clear aligner therapy and to identify rick factors that may predict such event.Methods The demographics and clinical variables of 94 patients undergoing clear aligner therapy (27 males and 67 females; average age: 27.60± 0.86 years) were recorded. Both patient-related and tooth-related attachment loss was recorded. The chi-square test and logistic regressive analysis were applied to identify the potential risk factors. SPSS for Mac (version 23.0, IBM, USA) was used for statistical analyses. P＜0.05 was considered statistically significant. Results Our study suggested that the risk factors for attachment loss include: frequent aligner removal (>= 5 times a day) (losing rate=60.0%, P=0.005); aligner wear time less than 18 hours a day (losing rate=50.8%, P=0.014); eating without aligners inserted (losing rate=47.9%, P=0.034); utilizing aligner tray seaters (losing rate=48.2%, P=0.006) and unilateral mastication (losing rate=52.1%, P=0.002). The multivariable logistic regression analysis indicates that aligner wear time less than 18 hours a day (P=0.020, B=0.925), using aligner tray seaters (P=0.007, B=1.168) and unilateral mastication (P=0.034, B=-0.458) were considered independent factors that can predict the composite attachment loss in orthodontic clear aligner therapy.Conclusion Wearing aligner less than 18 hours a day, using aligner tray seaters and unilateral mastication may contribute to increased incidence of composite attachment loss during orthodontic clear aligner therapy.

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Potential risk factors and prevalence of Helicobacter pylori infection among adult patients with dyspepsia symptoms in Cameroon

BMC Infectious Diseases ◽

10.1186/s12879-018-3146-1 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 9

Author(s):

Laure Brigitte Kouitcheu Mabeku ◽

Michelle Larissa Noundjeu Ngamga ◽

Hubert Leundji

Keyword(s):

Risk Factors ◽

Helicobacter Pylori ◽

Potential Risk ◽

Helicobacter Pylori Infection ◽

Adult Patients ◽

Potential Risk Factors

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Assessment of risk factors contributing to carcass bruising in fed cattle at commercial slaughter facilities

Translational Animal Science ◽

10.2527/tas2017.0055 ◽

2017 ◽

Vol 1 (4) ◽

pp. 489-497 ◽

Cited By ~ 1

Author(s):

T. L. Lee ◽

C. D. Reinhardt ◽

S. J. Bartle ◽

C. I. Vahl ◽

M. Siemens ◽

...

Keyword(s):

Risk Factors ◽

Traumatic Event ◽

Traumatic Events ◽

Economic Loss ◽

Carcass Weight ◽

Holstein Cattle ◽

Beef Carcasses ◽

Related Risk ◽

Potential Risk Factors ◽

Multiple Variables

Abstract Cattle injuries can occur during transportation due to vehicle design, transport conditions, and loading or unloading procedures and lead to carcass bruising and economic loss due to decreased carcass value. The objectives of this study were to determine whether a relationship exists between trauma incurred during unloading and prevalence of carcass bruising in finished beef cattle at commercial slaughter facilities and determine related risk factors which contribute to both trauma and carcass bruising. Breed (classified as either Holstein cattle or beef breeds), sex, distance traveled, and trailer type (“fat/feeder combination” vs. “fat” trailer) were considered risk factors which may contribute to traumatic event prevalence. When carcass bruise prevalence within each lot was used as the dependent variable, breed, sex, distance traveled, traumatic event prevalence, ribeye area, fat thickness, yield grade, and average carcass weight were considered potential risk factors. Carcass bruises were categorized by location and size, according to the Harvest Audit Program Carcass Bruise Scoring System. Traumatic events were observed while cattle exited trailers onto the unloading docks, and were categorized by location on the animal. Average traumatic event prevalence per lot was 20.4% (± 1.11%). Average carcass bruise prevalence by lot was 68.2% (± 1.15%). There was an interaction between breed and trailer type when multiple linear regression was used to explore variables contributing to traumatic events observed at unloading (P ≤ 0.05). Traumatic events were not associated with prevalence of carcass bruising, while average carcass weight and breed were associated with carcass bruising prevalence. Carcass bruising was more prevalent in Holstein cattle than in cattle which were predominantly beef breeds (P ≤ 0.01). Average carcass weight was negatively associated with carcass bruise prevalence (P ≤ 0.05). The association between traumatic events at unloading and carcass bruising is not significant when multiple variables are considered, indicating that bruising may occur at numerous other points prior to and during the transportation process, including loading and transport, and that other variables can contribute to carcass bruise prevalence. These areas should be explored to determine all potential causes of bruising in beef carcasses, and to help implement prevention practices.

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Haemodynamic analysis of adult patients with moyamoya disease: CT perfusion and DSA gradings

Stroke and Vascular Neurology ◽

10.1136/svn-2019-000317 ◽

2020 ◽

pp. svn-2019-000317

Author(s):

Zhiyong Shi ◽

Guofeng Ma ◽

Dong Zhang

Keyword(s):

Risk Factors ◽

Basal Ganglia ◽

Frontal Lobe ◽

Potential Risk ◽

Parietal Lobe ◽

Ct Perfusion ◽

Adult Patients ◽

Arterial Stenosis ◽

Significant Difference ◽

Potential Risk Factors

ObjectMoyamoya disease (MMD) is a common and chronic progressive stenotic-occlusive cerebrovascular disease in Eastern Asia. To evaluate the hemispheric haemodynamic status of adult patients with MMD, we explored the potential risk factors of hemispheric perfusion alterations with CT perfusion (CTP) and DSA.MethodsWe retrospectively reviewed 44 male and 44 female (176 hemispheres) adult patients with MMD who had both DSA and CTP. Data on cerebral blood perfusion (CBF), cerebral blood volume (CBV), mean transmit time (MTT), time to peak (TTP) of cerebral hemisphere and cerebellum were gathered and difference of relative haemodynamic parameters between different subgroups were assessed with independent sample t analysis, one-way analysis of variance and general linear regression analysis.ResultsParameters in regional CBF (rCBF) of frontal, temporal lobe and basal ganglia in female was more superior than male. rCBF, regional MTT (rMTT) and regional TTP (rTTP) in adult MMD patients with haemorrhage were superior than the ischaemic. With the increase of age, significant difference could be seen in rCBF and rCBV of thalamus. However, with progress of arterial stenosis, significant difference could only be obsevrved in rCBV, rMTT and rTTP, whereas rCBF had no significant difference. For increase of moyamoya vessels, significant decrease of rCBF could be seen in temporal and parietal lobe. With the increase of compensatory artery numbers, no significant difference could be seen in rCBF parameters (p>0.05).ConclusionsIn adult MMD patients, age, gender and clinical type were potential risk factors for the change of cerebral perfusion. When arterial stenosis is worsened, moyamoya vessels could alter perfusion of temporal and parietal lobe, but not frontal lobe. Extracranial/intracranial compensatory arteries could maintain microcirculation stability in frontal lobe and basal ganglia, indicating that the protection from extracranial compensatory arteries, a theoretic base for surgery treatment if necessary.

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Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study

Frontiers in Medicine ◽

10.3389/fmed.2020.544697 ◽

2020 ◽

Vol 7 ◽

Author(s):

Menghua Sun ◽

Yili Zhang ◽

Hao Shen ◽

Kai Sun ◽

Baoyu Qi ◽

...

Keyword(s):

Risk Factors ◽

Osteoporotic Fractures ◽

Mineral Density ◽

Clinical Trial Registry ◽

Cross Sectional ◽

Relevant Evidence ◽

Related Risk ◽

Potential Risk Factors ◽

Community Data

Background: Osteoporosis (OP) patients are usually asymptomatic until osteoporotic fractures occur, which makes early diagnosis and prevention difficult, and the associated fractures secondary to OP could be preventable with appropriate management. Therefore, early identification and relevant evidence-based management of OP could guide the prevention of subsequent fractures. This study will investigate the prevalence of OP and the incidence of osteoporotic fractures in Beijing community residents to further explore the related risk factors and put forward suggestions for people aged 45–80 years old.Methods: Over 2 years, this study will conduct an OP screening and a prospective follow-up in the Beijing community to investigate the incidence of osteoporotic fractures. The study will undertake bone mineral density detection, collect biological samples, and record information via questionnaires.Discussion: The study aims to investigate the potential risk factors for osteoporosis and explore syndromes from traditional Chinese medicine that are associated with this condition based on large samples from the Beijing community. Data on the incidence of osteoporotic fractures among community dwellers in Beijing over the two-years will be available on the Chinese clinical trial registry: ChiCTR-SOC-17013090.

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