scholarly journals Properties and Applications of PDMS for Biomedical Engineering: A Review

2021 ◽  
Vol 13 (1) ◽  
pp. 2
Author(s):  
Inês Miranda ◽  
Andrews Souza ◽  
Paulo Sousa ◽  
João Ribeiro ◽  
Elisabete M. S. Castanheira ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Rapid Prototyping ◽  
Biomedical Engineering ◽  
Soft Lithography ◽  
Medical Implants ◽  
Elastomeric Materials ◽  
Cardiovascular Flow ◽  
Biomedical Field ◽  
Biomedical Fields ◽  
Lithography Technique

Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and mechanical properties, which makes it well-suited for several engineering applications. Due to its biocompatibility, PDMS is widely used for biomedical purposes. This widespread use has also led to the massification of the soft-lithography technique, introduced for facilitating the rapid prototyping of micro and nanostructures using elastomeric materials, most notably PDMS. This technique has allowed advances in microfluidic, electronic and biomedical fields. In this review, an overview of the properties of PDMS and some of its commonly used treatments, aiming at the suitability to those fields’ needs, are presented. Applications such as microchips in the biomedical field, replication of cardiovascular flow and medical implants are also reviewed.

Biomedical materials: A review of titanium based alloys

2020 ◽  
pp. 095440622096769
Author(s):  
FA Anene ◽  
CN Aiza Jaafar ◽  
I Zainol ◽  
MA Azmah Hanim ◽  
MT Suraya
Keyword(s):  
Mechanical Properties ◽  
Vital Role ◽  
Light Weight ◽  
Medical Implants ◽  
Good Corrosion Resistance ◽  
Human Bones ◽  
Ti Alloys ◽  
Low Elastic Modulus ◽  
Production Industry ◽  
Biomedical Fields

The sterling mechanical properties of titanium alloys have distinguished them as an essential material for varied applications especially in biomedical fields. The combination of good corrosion resistance in addition to light weight, non-toxicity and an outstanding biocompatibility makes them a sought-after material for production of medical implants. Owing to the surging demand for durable implants, it has become exigent for increased developmental researches on biomaterials to be accelerated. This will result in significant increase in implant production and Ti alloys will play a vital role among the several materials presently in use. Hence, this review critically analysed the important roles Ti alloys have played thus far in the implant production industry and recent development of titanium-based alloys with low elastic modulus similar to human bones as well as improved biocompatibility and wear resistance.

Hydrogels as Antibacterial Biomaterials

2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Water Content ◽  
Oxygen Permeability ◽  
Structural Diversity ◽  
High Water ◽  
Clinical Applications ◽  
High Water Content ◽  
Biomedical Field

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.

scholarly journals Graphene Integrated Hydrogels Based Biomaterials in Photothermal Biomedicine

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 906
Author(s):  
Le Minh Tu Phan ◽  
Thuy Anh Thu Vo ◽  
Thi Xoan Hoang ◽  
Sungbo Cho
Keyword(s):  
Photothermal Therapy ◽  
Biomedical Applications ◽  
High Light ◽  
Conversion Materials ◽  
Potential Applications ◽  
Good Biocompatibility ◽  
Biomedical Field ◽  
Hydrogel Composites ◽  
Material Fabrication ◽  
Biomedical Fields

Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.

Microfluidics 4: PDMS Chip Soft Lithography v2

2021 ◽  
Author(s):  
Serhat Sevli ◽  
not provided C. Yunus Sahan
Keyword(s):  
Soft Lithography ◽  
Cost Effective ◽  
Cnc Machining ◽  
3D Printed ◽  
Low Volume ◽  
Pdms Chip ◽  
Application Specific ◽  
Lithography Technique

Microfluidics materials are of various types and application-specific. PDMS is one of the most preferred and cost-effective solutions for research and low-volume manufacturing. After having the mold, PDMS replicas are generated by a technique called soft-lithography. This protocol describes the preparation of PDMS microchannels using SU8 molds, 3D Printed resin molds, and/or metal molds by the soft lithography technique, SLA printing, or CNC machining.

scholarly journals Influence of cutting parameters on surface quality when machining a CoCrWNi alloy

2018 ◽  
Vol 178 ◽  
pp. 01009
Author(s):  
Manuela-Roxana Dijmărescu ◽  
Ioan-Cristian Tarbă ◽  
Maria-Cristina Dijmărescu ◽  
Vlad Gheorghiţă
Keyword(s):  
Mechanical Properties ◽  
Surface Roughness ◽  
Surface Quality ◽  
Cutting Parameters ◽  
Medical Applications ◽  
Medical Implants

Due to their excellent biocompatibility and mechanical properties, the use of Co-Cr based alloys in medical applications has increased substantially. An important characteristic of the medical implants is their surface quality, this being a significant constraint when machining this kind of products. The aim of this paper is to present a research conducted in order to determine and expose the influence of turning cutting parameters on the surface roughness of a CoCrWNi alloy.

scholarly journals Second-generation Titanium alloys Ti-15Mo and Ti-13Nb-13Zr: A Comparison of the Mechanical Properties for Implant Applications

2020 ◽  
Vol 321 ◽  
pp. 05006
Author(s):  
Florian Brunke ◽  
Carsten Siemers ◽  
Joachim Rösler
Keyword(s):  
Mechanical Properties ◽  
Titanium Alloys ◽  
Second Generation ◽  
Stress Shielding ◽  
Medical Engineering ◽  
High Strength ◽  
Medical Implants ◽  
Alloying Element ◽  
Bone Degradation ◽  
First Choice

Due to their outstanding mechanical properties, excellent corrosion resistance and biocompatibility titanium and titanium alloys are the first choice for medical engineering products. Alloys currently used for implant applications are Ti-6Al-4V (ELI) and Ti-6Al-7Nb. Both alloys belong to the class of (α+β)-alloys and contain aluminium as an alloying element. Aluminium is cytotoxic and can cause breast cancer. In addition, the stiffness of (α+β)-alloys is relatively high which can lead to stress shielding, bone degradation and implant loss. For this reason, second-generation titanium alloys like Ti-15Mo (solute-lean metastable β-alloy) and Ti-13Nb-13Zr (β-rich (α+β)-alloy) have been developed. However, their application in medical implants is limited due to a relatively low strength. Therefore, in the present study, the mechanical properties of Ti-15Mo and Ti-13Nb-13Zr have been optimised by thermomechanical treatments to achieve high strengths combined with low stiffnesses. Different phase compositions have been used, namely, α-, β- and ω-phase in Ti-15Mo and α-, β- and αʺ-phase in Ti-13Nb-13Zr. For Ti-15Mo, the required mechanical properties’ combination could not be achieved whereas Ti-13Nb-13Zr showed high strength and a low Young’s modulus after a dedicated thermo-mechanical treatment. This makes the latter alloy a good option for replacing the (α+β)-alloys in implant applications in the future.

Microfluidics 4: PDMS Chip Soft Lithography v2

2021 ◽  
Author(s):  
Serhat Sevli ◽  
not provided C. Yunus Sahan
Keyword(s):  
Soft Lithography ◽  
Cost Effective ◽  
Cnc Machining ◽  
3D Printed ◽  
Low Volume ◽  
Pdms Chip ◽  
Application Specific ◽  
Lithography Technique

Microfluidics materials are of various types and application-specific. PDMS is one of the most preferred and cost-effective solutions for research and low-volume manufacturing. After having the mold, PDMS replicas are generated by a technique called soft-lithography. This protocol describes the preparation of PDMS microchannels using SU8 molds, 3D Printed resin molds, and/or metal molds by the soft lithography technique, SLA printing, or CNC machining.

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