scholarly journals Personalized Characterization of Emotional States in Patients with Bipolar Disorder

Mathematics ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1174
Author(s):  
Pavel Llamocca ◽  
Victoria López ◽  
Matilde Santos ◽  
Milena Čukić

There is strong clinical evidence from the current literature that certain psychological and physiological indicators are closely related to mood changes. However, patients with mental illnesses who present similar behavior may be diagnosed differently, which is why a personalized study of each patient is necessary. Following previous promising results in the detection of depression, in this work, supervised machine learning (ML) algorithms were applied to classify the different states of patients diagnosed with bipolar depressive disorder (BDD). The purpose of this study was to provide relevant information to medical staff and patients’ relatives in order to help them make decisions that may lead to a better management of the disease. The information used was collected from BDD patients through wearable devices (smartwatches), daily self-reports, and medical observation at regular appointments. The variables were processed and then statistical techniques of data analysis, normalization, noise reduction, and feature selection were applied. An individual analysis of each patient was carried out. Random Forest, Decision Trees, Logistic Regression, and Support Vector Machine algorithms were applied with different configurations. The results allowed us to draw some conclusions. Random Forest achieved the most accurate classification, but none of the applied models were the best technique for all patients. Besides, the classification using only selected variables produced better results than using all available information, though the amount and source of the relevant variables differed for each patient. Finally, the smartwatch was the most relevant source of information.

2020 ◽  
Author(s):  
Claire W. Jin ◽  
Ame Osotsi ◽  
Zita Oravecz

AbstractStress management is a pervasive issue in the modern high schooler’s life. Despite many efforts to support adolescents’ mental well-being, teenagers often fail to recognize signs of high stress and anxiety until their emotions have escalated. Being able to identify early signs of these intense emotional states and predict their onset using physiological signals collected passively in real-time could help teenagers improve their awareness of their emotional well-being and take a more proactive approach to managing their emotions. To evaluate the potential of this approach, we collected data from high schoolers with Empatica E4 wearable health monitors (wristband) while they were living their daily lives. The data consisted of stressful event reports and physiological markers over the course of 4 weeks. We developed a random forest model and a support vector machine model and systematically assessed their performance in terms of predicting the onset of stress events and identifying physiological signals of stress. The models showed strong performance in terms of these measures and provided insights on physiological indicators of adolescent stress.


2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Kerry E. Poppenberg ◽  
Vincent M. Tutino ◽  
Lu Li ◽  
Muhammad Waqas ◽  
Armond June ◽  
...  

Abstract Background Intracranial aneurysms (IAs) are dangerous because of their potential to rupture. We previously found significant RNA expression differences in circulating neutrophils between patients with and without unruptured IAs and trained machine learning models to predict presence of IA using 40 neutrophil transcriptomes. Here, we aim to develop a predictive model for unruptured IA using neutrophil transcriptomes from a larger population and more robust machine learning methods. Methods Neutrophil RNA extracted from the blood of 134 patients (55 with IA, 79 IA-free controls) was subjected to next-generation RNA sequencing. In a randomly-selected training cohort (n = 94), the Least Absolute Shrinkage and Selection Operator (LASSO) selected transcripts, from which we constructed prediction models via 4 well-established supervised machine-learning algorithms (K-Nearest Neighbors, Random Forest, and Support Vector Machines with Gaussian and cubic kernels). We tested the models in the remaining samples (n = 40) and assessed model performance by receiver-operating-characteristic (ROC) curves. Real-time quantitative polymerase chain reaction (RT-qPCR) of 9 IA-associated genes was used to verify gene expression in a subset of 49 neutrophil RNA samples. We also examined the potential influence of demographics and comorbidities on model prediction. Results Feature selection using LASSO in the training cohort identified 37 IA-associated transcripts. Models trained using these transcripts had a maximum accuracy of 90% in the testing cohort. The testing performance across all methods had an average area under ROC curve (AUC) = 0.97, an improvement over our previous models. The Random Forest model performed best across both training and testing cohorts. RT-qPCR confirmed expression differences in 7 of 9 genes tested. Gene ontology and IPA network analyses performed on the 37 model genes reflected dysregulated inflammation, cell signaling, and apoptosis processes. In our data, demographics and comorbidities did not affect model performance. Conclusions We improved upon our previous IA prediction models based on circulating neutrophil transcriptomes by increasing sample size and by implementing LASSO and more robust machine learning methods. Future studies are needed to validate these models in larger cohorts and further investigate effect of covariates.


Atmosphere ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 701
Author(s):  
Bong-Chul Seo

This study describes a framework that provides qualitative weather information on winter precipitation types using a data-driven approach. The framework incorporates the data retrieved from weather radars and the numerical weather prediction (NWP) model to account for relevant precipitation microphysics. To enable multimodel-based ensemble classification, we selected six supervised machine learning models: k-nearest neighbors, logistic regression, support vector machine, decision tree, random forest, and multi-layer perceptron. Our model training and cross-validation results based on Monte Carlo Simulation (MCS) showed that all the models performed better than our baseline method, which applies two thresholds (surface temperature and atmospheric layer thickness) for binary classification (i.e., rain/snow). Among all six models, random forest presented the best classification results for the basic classes (rain, freezing rain, and snow) and the further refinement of the snow classes (light, moderate, and heavy). Our model evaluation, which uses an independent dataset not associated with model development and learning, led to classification performance consistent with that from the MCS analysis. Based on the visual inspection of the classification maps generated for an individual radar domain, we confirmed the improved classification capability of the developed models (e.g., random forest) compared to the baseline one in representing both spatial variability and continuity.


2020 ◽  
Vol 11 (40) ◽  
pp. 8-23
Author(s):  
Pius MARTHIN ◽  
Duygu İÇEN

Online product reviews have become a valuable source of information which facilitate customer decision with respect to a particular product. With the wealthy information regarding user's satisfaction and experiences about a particular drug, pharmaceutical companies make the use of online drug reviews to improve the quality of their products. Machine learning has enabled scientists to train more efficient models which facilitate decision making in various fields. In this manuscript we applied a drug review dataset used by (Gräβer, Kallumadi, Malberg,& Zaunseder, 2018), available freely from machine learning repository website of the University of California Irvine (UCI) to identify best machine learning model which provide a better prediction of the overall drug performance with respect to users' reviews. Apart from several manipulations done to improve model accuracy, all necessary procedures required for text analysis were followed including text cleaning and transformation of texts to numeric format for easy training machine learning models. Prior to modeling, we obtained overall sentiment scores for the reviews. Customer's reviews were summarized and visualized using a bar plot and word cloud to explore the most frequent terms. Due to scalability issues, we were able to use only the sample of the dataset. We randomly sampled 15000 observations from the 161297 training dataset and 10000 observations were randomly sampled from the 53766 testing dataset. Several machine learning models were trained using 10 folds cross-validation performed under stratified random sampling. The trained models include Classification and Regression Trees (CART), classification tree by C5.0, logistic regression (GLM), Multivariate Adaptive Regression Spline (MARS), Support vector machine (SVM) with both radial and linear kernels and a classification tree using random forest (Random Forest). Model selection was done through a comparison of accuracies and computational efficiency. Support vector machine (SVM) with linear kernel was significantly best with an accuracy of 83% compared to the rest. Using only a small portion of the dataset, we managed to attain reasonable accuracy in our models by applying the TF-IDF transformation and Latent Semantic Analysis (LSA) technique to our TDM.


Author(s):  
Prathima P

Abstract: Fall is a significant national health issue for the elderly people, generally resulting in severe injuries when the person lies down on the floor over an extended period without any aid after experiencing a great fall. Thus, elders need to be cared very attentively. A supervised-machine learning based fall detection approach with accelerometer, gyroscope is devised. The system can detect falls by grouping different actions as fall or non-fall events and the care taker is alerted immediately as soon as the person falls. The public dataset SisFall with efficient class of features is used to identify fall. The Random Forest (RF) and Support Vector Machine (SVM) machine learning algorithms are employed to detect falls with lesser false alarms. The SVM algorithm obtain a highest accuracy of 99.23% than RF algorithm. Keywords: Fall detection, Machine learning, Supervised classification, Sisfall, Activities of daily living, Wearable sensors, Random Forest, Support Vector Machine


2020 ◽  
Author(s):  
Sicheng Zhou ◽  
Yunpeng Zhao ◽  
Jiang Bian ◽  
Ann F Haynos ◽  
Rui Zhang

BACKGROUND Eating disorders (EDs) are a group of mental illnesses that have an adverse effect on both mental and physical health. As social media platforms (eg, Twitter) have become an important data source for public health research, some studies have qualitatively explored the ways in which EDs are discussed on these platforms. Initial results suggest that such research offers a promising method for further understanding this group of diseases. Nevertheless, an efficient computational method is needed to further identify and analyze tweets relevant to EDs on a larger scale. OBJECTIVE This study aims to develop and validate a machine learning–based classifier to identify tweets related to EDs and to explore factors (ie, topics) related to EDs using a topic modeling method. METHODS We collected potential ED-relevant tweets using keywords from previous studies and annotated these tweets into different groups (ie, ED relevant vs irrelevant and then promotional information vs laypeople discussion). Several supervised machine learning methods, such as convolutional neural network (CNN), long short-term memory (LSTM), support vector machine, and naïve Bayes, were developed and evaluated using annotated data. We used the classifier with the best performance to identify ED-relevant tweets and applied a topic modeling method—Correlation Explanation (CorEx)—to analyze the content of the identified tweets. To validate these machine learning results, we also collected a cohort of ED-relevant tweets on the basis of manually curated rules. RESULTS A total of 123,977 tweets were collected during the set period. We randomly annotated 2219 tweets for developing the machine learning classifiers. We developed a CNN-LSTM classifier to identify ED-relevant tweets published by laypeople in 2 steps: first relevant versus irrelevant (F<sub>1</sub> score=0.89) and then promotional versus published by laypeople (F<sub>1</sub> score=0.90). A total of 40,790 ED-relevant tweets were identified using the CNN-LSTM classifier. We also identified another set of tweets (ie, 17,632 ED-relevant and 83,557 ED-irrelevant tweets) posted by laypeople using manually specified rules. Using CorEx on all ED-relevant tweets, the topic model identified 162 topics. Overall, the coherence rate for topic modeling was 77.07% (1264/1640), indicating a high quality of the produced topics. The topics were further reviewed and analyzed by a domain expert. CONCLUSIONS A developed CNN-LSTM classifier could improve the efficiency of identifying ED-relevant tweets compared with the traditional manual-based method. The CorEx topic model was applied on the tweets identified by the machine learning–based classifier and the traditional manual approach separately. Highly overlapping topics were observed between the 2 cohorts of tweets. The produced topics were further reviewed by a domain expert. Some of the topics identified by the potential ED tweets may provide new avenues for understanding this serious set of disorders.


2021 ◽  
Vol 10 (6) ◽  
pp. 3220-3227
Author(s):  
Van-Dung Pham ◽  
Thanh-Long Cung

The purpose of this paper is to propose an approach of re-organizing input data to recognize emotion based on short signal segments and increase the quality of emotional recognition using physiological signals. MIT's long physiological signal set was divided into two new datasets, with shorter and overlapped segments. Three different classification methods (support vector machine, random forest, and multilayer perceptron) were implemented to identify eight emotional states based on statistical features of each segment in these two datasets. By re-organizing the input dataset, the quality of recognition results was enhanced. The random forest shows the best classification result among three implemented classification methods, with an accuracy of 97.72% for eight emotional states, on the overlapped dataset. This approach shows that, by re-organizing the input dataset, the high accuracy of recognition results can be achieved without the use of EEG and ECG signals.


Diagnostics ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 421
Author(s):  
Satyabrata Aich ◽  
Jinyoung Youn ◽  
Sabyasachi Chakraborty ◽  
Pyari Mohan Pradhan ◽  
Jin-han Park ◽  
...  

Fluctuations in motor symptoms are mostly observed in Parkinson’s disease (PD) patients. This characteristic is inevitable, and can affect the quality of life of the patients. However, it is difficult to collect precise data on the fluctuation characteristics using self-reported data from PD patients. Therefore, it is necessary to develop a suitable technology that can detect the medication state, also termed the “On”/“Off” state, automatically using wearable devices; at the same time, this could be used in the home environment. Recently, wearable devices, in combination with powerful machine learning techniques, have shown the potential to be effectively used in critical healthcare applications. In this study, an algorithm is proposed that can detect the medication state automatically using wearable gait signals. A combination of features that include statistical features and spatiotemporal gait features are used as inputs to four different classifiers such as random forest, support vector machine, K nearest neighbour, and Naïve Bayes. In total, 20 PD subjects with definite motor fluctuations have been evaluated by comparing the performance of the proposed algorithm in association with the four aforementioned classifiers. It was found that random forest outperformed the other classifiers with an accuracy of 96.72%, a recall of 97.35%, and a precision of 96.92%.


Symmetry ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 403
Author(s):  
Muhammad Waleed ◽  
Tai-Won Um ◽  
Tariq Kamal ◽  
Syed Muhammad Usman

In this paper, we apply the multi-class supervised machine learning techniques for classifying the agriculture farm machinery. The classification of farm machinery is important when performing the automatic authentication of field activity in a remote setup. In the absence of a sound machine recognition system, there is every possibility of a fraudulent activity taking place. To address this need, we classify the machinery using five machine learning techniques—K-Nearest Neighbor (KNN), Support Vector Machine (SVM), Decision Tree (DT), Random Forest (RF) and Gradient Boosting (GB). For training of the model, we use the vibration and tilt of machinery. The vibration and tilt of machinery are recorded using the accelerometer and gyroscope sensors, respectively. The machinery included the leveler, rotavator and cultivator. The preliminary analysis on the collected data revealed that the farm machinery (when in operation) showed big variations in vibration and tilt, but observed similar means. Additionally, the accuracies of vibration-based and tilt-based classifications of farm machinery show good accuracy when used alone (with vibration showing slightly better numbers than the tilt). However, the accuracies improve further when both (the tilt and vibration) are used together. Furthermore, all five machine learning algorithms used for classification have an accuracy of more than 82%, but random forest was the best performing. The gradient boosting and random forest show slight over-fitting (about 9%), but both algorithms produce high testing accuracy. In terms of execution time, the decision tree takes the least time to train, while the gradient boosting takes the most time.


Author(s):  
Marina Azer ◽  
◽  
Mohamed Taha ◽  
Hala H. Zayed ◽  
Mahmoud Gadallah

Social media presence is a crucial portion of our life. It is considered one of the most important sources of information than traditional sources. Twitter has become one of the prevalent social sites for exchanging viewpoints and feelings. This work proposes a supervised machine learning system for discovering false news. One of the credibility detection problems is finding new features that are most predictive to better performance classifiers. Both features depending on new content, and features based on the user are used. The features' importance is examined, and their impact on the performance. The reasons for choosing the final feature set using the k-best method are explained. Seven supervised machine learning classifiers are used. They are Naïve Bayes (NB), Support vector machine (SVM), Knearest neighbors (KNN), Logistic Regression (LR), Random Forest (RF), Maximum entropy (ME), and conditional random forest (CRF). Training and testing models were conducted using the Pheme dataset. The feature's analysis is introduced and compared to the features depending on the content, as the decisive factors in determining the validity. Random forest shows the highest performance while using user-based features only and using a mixture of both types of features; features depending on content and the features based on the user, accuracy (82.2 %) in using user-based features only. We achieved the highest results by using both types of features, utilizing random forest classifier accuracy(83.4%). In contrast, logistic regression was the best as to using features that are based on contents. Performance is measured by different measurements accuracy, precision, recall, and F1_score. We compared our feature set with other studies' features and the impact of our new features. We found that our conclusions exhibit high enhancement concerning discovering and verifying the false news regarding the discovery and verification of false news, comparing it to the current results of how it is developed.


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