Lactate Threshold Training Program on Patients with Multiple Sclerosis: A Multidisciplinary Approach

Physical activity could play a key role in improving the quality of life, particularly in patients with nervous system diseases such as multiple sclerosis (MS). Through lactacid anaerobic training, this study aims to investigate the effects at a bio-psycho-physical level to counteract the chronic fatigue associated with the pathology, and to improve mental health at a psychological and neurotrophic level. Eight subjects (age: 34.88 ± 4.45 years) affected by multiple sclerosis were involved. A lactate threshold training program was administered biweekly for 12 weeks at the beginning of the study (T0), at the end of the study (T1) and at 9 months after the end of the study (T2), with physical, psychological and hematochemicals parameters, and dietary habits being tested. The results obtained confirmed that lactacid exercise can influence brain-derived neurotrophic factor (BDNF) levels as well as dehydroepiandrosterone sulfate (DHEAS) levels. In addition, levels of baseline lactate, which could be best used as an energy substrate, showed a decrease after the protocol training. Self-efficacy regarding worries and concerns management significantly increased from T0 to T1. The eating attitudes test (EAT-26) did not highlight any eating disease in the patients with a normal diet enrolled in our study. Physical exercise also greatly influenced the patients psychologically and emotionally, increasing their self-esteem. Lactate threshold training, together with dietary habits, appears to exert synergic positive effects on inflammation, neural plasticity and neuroprotection, producing preventive effects on MS symptoms and progression.

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Orthorexia Nervosa: Examining Two Self-Report Measures and the Predictors of Orthorexic Symptoms in Elite and Recreational Athletes

Current Developments in Nutrition ◽

10.1093/cdn/nzab058_008 ◽

2021 ◽

Vol 5 (Supplement_2) ◽

pp. 1295-1295

Author(s):

Kyriaki Myrissa ◽

Laura Jackson ◽

Eirini Kelaiditi

Keyword(s):

Healthy Eating ◽

Dietary Habits ◽

Short Form ◽

Linear Regression Analysis ◽

Eating Attitudes ◽

Assessment Tools ◽

Self Report ◽

Orthorexia Nervosa ◽

Recreational Athletes ◽

Eat 26

Abstract Objectives Orthorexia nervosa (ON) is characterised by a pathological fixation on healthy eating. Athletes strive for athletic performance through restricted dietary habits which may lead to the presence of ON symptoms. The aim of the present study was to investigate the underlying structures of two self-report measures of ON, assess differences in ON symptoms between elite and recreational athletes, and determine potential predictors of ON symptomatology. Methods Cross-sectional study of 215 elite (n = 59; mean age 26.71 ± 6.83 years) and recreational athletes (n = 156; mean age 36.13 ± 14.33 years) completed the Teruel Orthorexia Scale (TOS), Eating Habits Questionnaire (EHQ), Short Form Food Frequency Questionnaire (SFFFQ), Eating Attitudes Test-26 (EAT-26), and the Hewitt-Flett Multidimensional Perfectionism Scale Short Form (HF-MPS-SF). Results Factor analysis revealed two-factor structures for both the TOS and the EHQ. Elite athletes exhibited higher scores for ‘healthy orthorexia’ (HeOr) (P = .016), ‘knowledge of healthy eating’ (P = .038) (EHQ-Knowledge), diet quality score (DQS) (P = .013) and self-orientated perfectionism scores (P = .032) compared to recreational athletes. Multiple linear regression analysis revealed DQS to be a consistent and significant predictor of all ON symptoms (both TOS and EHQ). BMI was negatively associated with HeOr (β = –.21, P < .001). EAT-26 dieting, bulimia and oral subscales predicted ‘orthorexia nervosa’ (OrNe; smallest P = .015) and ‘problems associated with healthy eating’ (EHQ-Problems; smallest P = .012). Other-orientated perfectionism (OOP) was the only perfectionism construct to predict HeOr (β = .23, P < .01), EHQ-Knowledge (β = .34, P < .001), EHQ-Problems (β = .18, P < .01) and EHQ-Total (β = .27, P < .001). Conclusions Findings suggest TOS is a reliable measure of ON symptomatology in athletes and further refinement of the EHQ is required. Improvements in assessment tools, study methodology and classification of athlete characteristics are required to advance our understanding of ON in athlete populations. Funding Sources None.

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Can having a sibling with type 1 diabetes cause disordered eating behaviors?

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2017-0533 ◽

2018 ◽

Vol 31 (7) ◽

pp. 711-716

Author(s):

Sinem Akgül ◽

Ayfer Alikaşifoğlu ◽

Alev Özon ◽

Nazlı Gönç ◽

Yasemin Düzçeker ◽

...

Keyword(s):

Type 1 Diabetes ◽

Disordered Eating ◽

Eating Behaviors ◽

Dietary Habits ◽

Eating Attitudes ◽

Control Group ◽

Dietary Recall ◽

Increased Risk ◽

Eat 26

Abstract Background Adolescents with type 1 diabetes mellitus (T1DM) are at an increased risk of eating disturbances. The aim of this study was to evaluate whether the risk of a disordered eating behavior (DEB) also applies to the well sibling sharing the same environment. Methods Well siblings were included if they were 10–18 years old, had a sibling with a T1DM diagnosis for at least 6 months and lived with the sibling during the illness. The control group was comprised of healthy participants recruited from the outpatient clinic with no family history of T1DM. Participants completed a four-part questionnaire concerning their eating behaviors that was developed by the study team. This survey aimed to evaluate the dietary habits and eating patterns. All participants completed the Eating Attitudes Test-26 (EAT-26) and a 24-h food dietary recall. Any participant with a high EAT-26 score or that seemed to be at risk according to the questionnaire was re-evaluated. Results Eight cases (33.3%) in the well sibling group had either a total and/or subgroup pathological score. Three of them were found to have DEB and one case was diagnosed with anorexia nervosa (AN). In the control group, five cases (17.2%) had either a total and/or subgroup pathological score. Three of these cases were found to have DEB, no cases were diagnosed with an eating disorder. There were no statistically significant differences in the EAT-26 scores between the groups. Conclusions Although a direct relationship was not observed, the probability of having a pathologic EAT-26 score was higher in the group with a sibling with T1DM.

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Detection of Dysbiosis and Increased Intestinal Permeability in Brazilian Patients with Relapsing–Remitting Multiple Sclerosis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094621 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4621

Author(s):

Felipe Papa Pellizoni ◽

Aline Zazeri Leite ◽

Nathália de Campos Rodrigues ◽

Marcelo Jordão Ubaiz ◽

Marina Ignácio Gonzaga ◽

...

Keyword(s):

Multiple Sclerosis ◽

Gut Microbiota ◽

Intestinal Permeability ◽

Dietary Habits ◽

Dietary Interventions ◽

Chi Square ◽

16S Sequencing ◽

Intestinal Dysbiosis ◽

Relapsing Remitting ◽

Relapsing Remitting Multiple Sclerosis

Dysbiosis, associated with barrier disruption and altered gut–brain communications, has been associated with multiple sclerosis (MS). In this study, we evaluated the gut microbiota in relapsing–remitting patients (RRMS) receiving disease-modifying therapies (DMTs) and correlated these data with diet, cytokines levels, and zonulin concentrations. Stool samples were used for 16S sequencing and real-time PCR. Serum was used for cytokine determination by flow cytometry, and zonulin quantification by ELISA. Pearson’s chi-square, Mann–Whitney, and Spearman’s correlation were used for statistical analyses. We detected differences in dietary habits, as well as in the gut microbiota in RRMS patients, with predominance of Akkermansia muciniphila and Bacteroides vulgatus and decreased Bifidobacterium. Interleukin-6 concentrations were decreased in treated patients, and we detected an increased intestinal permeability in RRMS patients when compared with controls. We conclude that diet plays an important role in the composition of the gut microbiota, and intestinal dysbiosis, detected in RRMS patients could be involved in increased intestinal permeability and affect the clinical response to DTMs. The future goal is to predict therapeutic responses based on individual microbiome analyses (personalized medicine) and propose dietary interventions and the use of probiotics or other microbiota modulators as adjuvant therapy to enhance the therapeutic efficacy of DMTs.

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Nutritional status of multiple sclerosis (MS) patients attending Kasr Alainy MS unit: an exploratory cross-sectional study

Journal of Egyptian Public Health Association ◽

10.1186/s42506-021-00080-3 ◽

2021 ◽

Vol 96 (1) ◽

Author(s):

Zeinab E. Afifi ◽

Rania I. Shehata ◽

Asmaa F. El Sayed ◽

El Sayed M. Hammad ◽

Marwa R. Salem

Keyword(s):

Multiple Sclerosis ◽

Nutritional Status ◽

Dietary Habits ◽

Care Service ◽

Structured Interview ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Level Measurement ◽

Impact Scale

Abstract Background Nutrition was claimed to be a factor in MS causation, course, complications, and management. Several studies were conducted to assess the nutritional status of MS patients; however, few studies were conducted to assess this problem in Egypt. Therefore, the purpose of the current study was to assess the nutritional status of a sample of MS patients. Methods The researchers conducted an exploratory cross-sectional study among 76 relapsing-remitting MS (RRMS) patients attending Kasr Alainy Multiple Sclerosis Unit (KAMSU) from October 2018 to January 2019 to assess the nutritional status of a sample of MS patients. Data were collected using a structured interview questionnaire including an inquiry about the socioeconomic status, and nutritional status using anthropometric measurements, patient-generated subjective global assessment (PG-SGA), semi-quantitative food frequency questionnaires (SQFFQ), and hemoglobin level measurement. Assessment of fatigue was done using the Modified Fatigue Impact Scale 5-items version. Results The mean age of the study participants was 30 ± 6 years. The disease duration ranged from 2 to 264 months. Malnutrition was prevalent among 67.1% (27.6 % overweight, 36.8% obese, and 2.6% underweight). Half of the investigated patients were anemic. According to the PG-SGA, more than half of the studied patients (53.9%) were classified as moderately or suspected malnourished. The unhealthy dietary habits such as taking only a few meals, junk food intake and skipping breakfast were observed in considerable proportions of the group. The SQFFQ revealed overconsumption of energy and fat, and less than acceptable consumption of dietary fibers by most of the studied patients. Conclusions Overweight, obesity, anemia, and unhealthy dietary habits were prevalent among the RRMS patients attending the KAMSU. Nutrition care service is extremely needed for this group of patients.

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Cardiac Rehabilitation in German Speaking Countries of Europe—Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH—Part 2

Journal of Clinical Medicine ◽

10.3390/jcm10143071 ◽

2021 ◽

Vol 10 (14) ◽

pp. 3071

Author(s):

Bernhard Schwaab ◽

Birna Bjarnason-Wehrens ◽

Karin Meng ◽

Christian Albus ◽

Annett Salzwedel ◽

...

Keyword(s):

Cardiac Rehabilitation ◽

Dietary Habits ◽

Prognostic Significance ◽

Clinical Results ◽

Arterial Disease ◽

Lifestyle Changes ◽

Positive Trend ◽

Clinical Effects ◽

Positive Effects ◽

German Speaking

Background: Scientific guidelines have been developed to update and harmonize exercise based cardiac rehabilitation (ebCR) in German speaking countries. Key recommendations for ebCR indications have recently been published in part 1 of this journal. The present part 2 updates the evidence with respect to contents and delivery of ebCR in clinical practice, focusing on exercise training (ET), psychological interventions (PI), patient education (PE). In addition, special patients’ groups and new developments, such as telemedical (Tele) or home-based ebCR, are discussed as well. Methods: Generation of evidence and search of literature have been described in part 1. Results: Well documented evidence confirms the prognostic significance of ET in patients with coronary artery disease. Positive clinical effects of ET are described in patients with congestive heart failure, heart valve surgery or intervention, adults with congenital heart disease, and peripheral arterial disease. Specific recommendations for risk stratification and adequate exercise prescription for continuous-, interval-, and strength training are given in detail. PI when added to ebCR did not show significant positive effects in general. There was a positive trend towards reduction in depressive symptoms for “distress management” and “lifestyle changes”. PE is able to increase patients’ knowledge and motivation, as well as behavior changes, regarding physical activity, dietary habits, and smoking cessation. The evidence for distinct ebCR programs in special patients’ groups is less clear. Studies on Tele-CR predominantly included low-risk patients. Hence, it is questionable, whether clinical results derived from studies in conventional ebCR may be transferred to Tele-CR. Conclusions: ET is the cornerstone of ebCR. Additional PI should be included, adjusted to the needs of the individual patient. PE is able to promote patients self-management, empowerment, and motivation. Diversity-sensitive structures should be established to interact with the needs of special patient groups and gender issues. Tele-CR should be further investigated as a valuable tool to implement ebCR more widely and effectively.

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Eating Disorders in Top Elite Beach Handball Players: Cross Sectional Study

Children ◽

10.3390/children8030245 ◽

2021 ◽

Vol 8 (3) ◽

pp. 245

Author(s):

Alejandro Martínez-Rodríguez ◽

Manuel Vicente-Martínez ◽

Javier Sánchez-Sánchez ◽

Laura Miralles-Amorós ◽

María Martínez-Olcina ◽

...

Keyword(s):

Eating Disorders ◽

Young Adults ◽

Body Composition ◽

Sports Medicine ◽

Eating Habits ◽

Cross Sectional Study ◽

Eating Attitudes ◽

Sectional Study ◽

Cross Sectional ◽

Eat 26

(1) Background: The preoccupation with the increasing appearance of eating disorders (ED) in athletes continues to grow, especially in athletes who practice team sports. ED severely affects the eating habits of the athletes, who tend to use unhealthy approaches to control their body weight. The development of nutritional education and early interventions by training staff is essential, and these factors are widely perceived as beneficial in sports medicine. This study evaluates the frequency at which beach handball (BH) players develop ED, also comparing the differences by sex and age (junior: adolescents vs. senior: young adults). In addition, the relation between body composition variables and ED was studied. (2) Methods: A descriptive and cross-sectional study was carried out in 69 top elite handball players (36 males and 33 females) from the Spanish National BH Team; who were separated by age (junior: adolescents and senior: young adults). The athletes completed the Eating Attitudes Test in its 26 item version (EAT-26). (3) Results: The prevalence of ED indicated that 11% of females had a high possibility of developing an ED, and 3% of males. Regarding the EAT-26 total score and subscales, no significant differences were found between female and male participants, or between the junior and senior categories. The correlations showed an association between body composition, in terms of body mass index, and the EAT-26 total score in both males and females. In the case of males, the correlation was negative. (4) Conclusions: Although there are no significant differences between sex or categories, it has been found that elite athletes are a population that is at high risk of developing ED.

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Eating disorders among health science students at a university in southern Brazil

Revista de Psiquiatria do Rio Grande do Sul ◽

10.1590/s0101-81082011005000002 ◽

2011 ◽

Vol 33 (1) ◽

pp. 14-19 ◽

Cited By ~ 9

Author(s):

Luiza do Nascimento Ghizoni Pereira ◽

Fabiana Schuelter Trevisol ◽

João Quevedo ◽

Luciano Kurtz Jornada

Keyword(s):

Eating Disorders ◽

Weight Loss ◽

University Students ◽

Eating Attitudes ◽

Health Science ◽

Science Students ◽

Southern Brazil ◽

Health Science Students ◽

Weight Loss Strategies ◽

Eat 26

OBJECTIVES: To analyze eating disorders among female university students and to assess the frequency of bulimia nervosa, anorexia nervosa, and inappropriate weight loss strategies in this population. METHODS: The sample comprised 214 female university students attending different health science programs at a university in southern Brazil, aged over 18 years, assessed using self-administered questionnaires. The 26-item version of the Eating Attitudes Test (EAT-26), the Bulimic Investigatory Test, Edinburgh (BITE), and a supplementary questionnaire covering data on weight status and inappropriate weight loss strategies were used to assess dietary abnormalities. RESULTS: Mean age (± standard deviation) was 21±9.93 years, and mean body mass index (BMI) was 21.1±2.59. Among the respondents, 72.9% said they would like to weigh less, 29% reported the use of different weight loss methods (diuretics were the most common, followed by laxatives, amphetamine-derived drugs, and self-induced vomiting). With regard to EAT-26 scores, 22.4% (95%CI 17.7-27.1) revealed abnormal feeding patterns; BITE indicated that 9.8% (95%CI 6.5-13.1) were at risk for developing bulimia and 36.9% (95%CI 31.5-42.3) required clinical evaluation. Mean BMI was lower among students with normal scores on both tests, but no association was found between BMI and satisfaction with own weight. CONCLUSION: There was a strong trend toward eating disorders in the health science students assessed, as demonstrated by EAT-26 and BITE scores; inadequate weight loss strategies are frequently used as well.

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Zinc-specific Food Frequency Questionnaire To Assess College Women’s Eating Habits

Canadian Journal of Dietetic Practice and Research ◽

10.3148/70.4.2009.204 ◽

2009 ◽

Vol 70 (4) ◽

pp. 204-208 ◽

Cited By ~ 2

Author(s):

Janet M. Lacey ◽

Deanne U. Zotter

Keyword(s):

Food Frequency Questionnaire ◽

Assessment Tool ◽

Eating Habits ◽

Eating Behaviour ◽

Eating Attitudes ◽

Eating Attitude ◽

Food Frequency ◽

Unhealthy Eating ◽

Starting Point ◽

Eat 26

Zinc deficiency has been reported in individuals with eating disorders, the risks of which increase during the adolescent and early adult years. A food frequency questionnaire (FFQ) specific for zinc-rich foods was tested for its usefulness in identifying problematic eating behaviour tendencies in college-age women. Ninety-two female students enrolled in a university introductory psychology course volunteered to complete demographic information, the Eating Attitudes Test (EAT-26), and a zinc-specific FFQ (ZnFFQ). Relationships among estimated zinc intakes, food/lifestyle habits, and eating attitude variables were examined. Twenty-five women had estimated intakes below the Recommended Dietary Allowance (RDA) for zinc. Individuals in the highest zinc intake group (over twice the RDA) had a tendency to score higher on the EAT-26 and the bulimia subscale. Vegetarians also scored high on the EAT-26. Although our data are limited, the ZnFFQ should be studied further to determine whether it could play a useful role in identifying individuals at risk for bulimia. The ZnFFQ is a simple, non-confrontational assessment tool and may be a helpful starting point for identifying women with unhealthy eating habits.

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Fatigue in multiple sclerosis compared with chronic fatigue syndrome: A quantitative assessment

Neurology ◽

10.1212/wnl.46.3.632 ◽

1996 ◽

Vol 46 (3) ◽

pp. 632-635 ◽

Cited By ~ 43

Author(s):

R. Djaldetti ◽

I. Ziv ◽

A. Achiron ◽

E. Melamed

Keyword(s):

Multiple Sclerosis ◽

Chronic Fatigue Syndrome ◽

Quantitative Assessment ◽

Chronic Fatigue ◽

Fatigue Syndrome

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BUSCA PELA MUSCULARIDADE, HUMOR E TRANSTORNOS ALIMENTARES EM ATLETAS DO SEXO MASCULINO

Revista Brasileira de Medicina do Esporte ◽

10.1590/1517-869220172301136184 ◽

2017 ◽

Vol 23 (1) ◽

pp. 37-41

Author(s):

Leonardo de Sousa Fortes ◽

Santiago Tavares Paes ◽

Dilson Borges Ribeiro Júnior ◽

Sebastião de Sousa Almeida ◽

Maria Elisa Caputo Ferreira

Keyword(s):

Eating Attitudes ◽

Drive For Muscularity ◽

Eating Attitudes Test ◽

Eat 26

RESUMO Introdução: Parece que a busca pela muscularidade pode ter relação com os transtornos alimentares (TA) em atletas do sexo masculino. Todavia, de acordo com nosso conhecimento, não existem estudos sobre esse tema. Objetivo: Analisar a relação da busca pela muscularidade e estado de humor com os transtornos alimentares nessa população. Métodos: Participaram do estudo 112 competidores de diversas modalidades esportivas, pertencentes a federações do sudeste brasileiro. Utilizou-se o Eating Attitudes Test (EAT-26), Drive for Muscularity Scale (DFM) e a Escala de Humor de Brunel (BRUMS) para avaliar, respectivamente, os comportamentos alimentares de risco de TA, a busca pela muscularidade e o estado de humor. Resultados: Os achados dos modelos de regressão hierárquica não demonstraram relação da busca pela muscularidade (p > 0,05) e do estado de humor (p > 0,05) com os transtornos alimentares. Todavia, os resultados indicaram diferença de busca pela muscularidade em razão das classificações do EAT-26 (p < 0,05), fato que não foi revelado para o estado de humor (p > 0,05). Conclusão: Concluiu-se que tanto o estado de humor quanto a busca pela muscularidade não se relacionaram com os transtornos alimentares em atletas do sexo masculino.

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