scholarly journals Comparison of Postural Features and Muscle Strength between Children with Idiopathic Short Stature and Healthy Peers in Relation to Physical Exercise

2020 ◽  
Vol 12 (9) ◽  
pp. 3639 ◽  
Author(s):  
Jessica Brusa ◽  
Maria Cristina Maggio ◽  
Daniele Zangla ◽  
Valerio Giustino ◽  
Ewan Thomas ◽  
...  

Previous research has reported that children with idiopathic short stature (ISS) showed functional and cognitive impairments. The purpose of this study was to compare muscle strength and body posture between children with ISS treated with growth hormone (GH) and healthy peers (healthy children, HC), and to analyze whether these parameters were affected by physical exercise. Eighteen children for the ISS group (mean age: 10.96 ± 1.68 years) and 26 children for the HC group (mean age: 10.19 ± 1.06 years) were recruited for the study. All participants performed the following assessments: handgrip and Sargent test for the muscle strength evaluation; baropodometric and stabilometric test for the posturographic measures. Data were analyzed with analysis of covariance (ANCOVA) using height and weight as covariate. Groups were then stratified into active and inactive and independent t-tests were used to determine differences between variables. Significance level was set to p < 0.05. Our results showed a significantly lower performance for both hands (p < 0.01) and a greater difference of plantar loading distribution between feet in the ISS compared to the HC groups (p < 0.01). In relation to physical exercise, the HC active group showed the highest handgrip strength values for both hands among the analyzed groups and, moreover, handgrip strength of both ISS active and inactive groups was significantly lower than corresponding CH peers for both hands. Although ISS and HC inactive groups reported an unequal plantar loading distribution between feet (p < 0.05), this asymmetry was not present in both ISS and HC active groups. We assume that GH therapy integrated with physical exercise in young patients with ISS could be suggested to increase muscle strength and body posture improving their quality of life.

QJM ◽  
2019 ◽  
Vol 112 (11) ◽  
pp. 847-853
Author(s):  
X Cao ◽  
Y Gu ◽  
J Fu ◽  
T Q C Vu ◽  
Q Zhang ◽  
...  

Abstract Background Sarcopenia is emerging as an important public health problem, and evidences have determined that poor sleep is associated with muscle strength, but the potential effects of excessive daytime sleepiness (EDS), snoring and witnessed apnea on handgrip strength have not been evaluated. Aim We aimed to examine the association between EDS, snoring, witnessed apnea and muscle strength in an adult population. Design Cross-sectional study. Methods This cross-sectional study comprised 19 434 adults. Handgrip strength was measured using a handheld digital dynamometer. EDS was assessed by Epworth Sleepiness Scale, snoring and witnessed apnea during sleep were reported through simple yes/no questions. Analysis of covariance was carried out to determine the association between EDS with snoring or witnessed apnea and muscle strength. Results The means (95% confidence interval) for average handgrip strength/body weight (kg/kg) across symptoms categories were 0.396 (0.333–0.472), 0.393 (0.330–0.467), 0.396 (0.333–0.471) and 0.386 (0.325–0.460) (P < 0.0001), respectively. Similar results were observed with maximal handgrip strength/body weight (kg/kg). Conclusions Self-reported EDS accompanied with snoring or apnea is associated with lowest handgrip strength, independently of confounding factors. Whether improvement of EDS, snoring and apnea, can ameliorate age-associated decline in muscle strength warrants further studies.


2021 ◽  
Vol 17 (2) ◽  
pp. 134-140
Author(s):  
Hamid Mehmood ◽  
Muhammad Yaqoob ◽  
Ejaz Mahmood Ahmad Qureshi ◽  
Saleem Rana ◽  
Syed Amir Gilani

Objective: To determine palmar grip force (PGF) in elderly population and its correlation with different parameters used in the usual practice of evaluation of nutritional status in elderly populaiton. Methodology: It was obsevational, cross-sectional study. 300 elderly people over 65 years old, who were doing gym exercises at UFC gym and Structure gym, Lahore from December 2019 to July 2020. HS was obtained using the digital dynamometer model EH101, using the average of three measurements. The cutoff point considered for low muscle strength was HS < 27 kg for men and < 16 kg for women. The standard has been taken according to the 2019 consensus of the European Working Group on Sarcopenia in Older People (EWGSOP2, version 2019). For the statistical analysis, the Statistical Package for Social Science 24.0 program was used and chi square test was applied, considering it significant when p <0.05. Results: The sample consisted of elderly people with a mean age of 71.71 ± 5.97 years, of which 28% were aged between 65 and 75 years and 51.66% were male. In the analysis of the HS, we found 57.9% of the elderly with loss of muscle strength due to non-exercise during COVID-19. The muscle circumference of the arm and tricipital skin fold indicators found the highest percentages of malnutrition, 44.1% and 57.8%, respectively. HS showed a positive association  between age and handgrip test levels. Conclusion: There was a high frequency of elderly people with impaired strength, but HS correlated only with APMT, not showing a direct relationship with other anthropometric parameters used in the routine practice of assessment with the elderly. Therefore, HS, or at least the evaluation of APMT, becomes indispensable for the evaluation and physical exercise training of elderly persons during COVID-19 pandemic.  


Author(s):  
Jessica Brusa ◽  
Maria Cristina Maggio ◽  
Valerio Giustino ◽  
Ewan Thomas ◽  
Daniele Zangla ◽  
...  

Background: Congenital hypothyroidism (CH) is an endocrine disease with a precocious significant impairment of growth and neuromotor development. Thyroid hormones are essential for central nervous system development, maturation, and myelination. Furthermore, thyroid hormone deficiency affects the function of several systems, including the musculoskeletal system. The disease has a significant incidence in the general population (1:3000–1:2000 newborns in Italy). The aim of the present study was to evaluate any differences in upper and lower limb strength, body sway, and plantar loading distribution in children with CH compared to healthy children. Methods: In this study, the case group was composed of children with CH (CHG), while the control group included healthy children (CG). Both groups comprised 19 children (CHG: female = 12; CG: female = 9). The maximum isometric handgrip strength and explosive-elastic lower limb strength were assessed with the handgrip test and the Sargent test, respectively. The stabilometric and baropodometric analyses were used to measure the Center of Pressure displacements and the plantar loading distribution between feet, respectively. The differences between groups were analyzed by a univariate analysis of covariance using as covariates weight and height with the significant level set at < 0.05. Results: We found that CHG children were shorter and thinner than CG ones (p < 0.05). No significant difference in the upper and lower limb strength was found between groups. CHG exhibited a significant greater Sway Path Length (p < 0.01) and Ellipse Surface (p < 0.05) than CG. Moreover, CHG displayed an asymmetric plantar loading distribution with a significant lower percentage in the right than in the left foot (p < 0.05). Moreover, a significant lower plantar loading percentage in the right foot of CHG than in the right foot of CG was observed (p < 0.05). Conclusions: These findings seem to suggest that CH does not affect muscle strength in early treated children. However, these patients show poor postural control ability and asymmetric plantar loading distribution. Increasing the physical activity in these children could improve their body posture.


2021 ◽  
Author(s):  
Maria Cristine Campos ◽  
Tatyana Nery ◽  
Ana Cristina de Bem Alves ◽  
Ana Elisa Speck ◽  
Danielle Soares Rocha Vieira ◽  
...  

Objective: This study aimed to evaluate the effects of physical rehabilitation for adults with sequelae after COVID-19. Methods: This clinical, nonrandomized, controlled, and open study will examine 82 participants who have met the inclusion criteria and who will be divided into treatment and control groups according to participant preference. The intervention group will receive face-to-face care; the control group will receive remote educational guidance for 8 weeks, with pre-post evaluations. The primary outcomes are dyspnea, fatigue, and exercise capacity; the secondary outcomes are lung function, heart rate variability, handgrip strength, knee extensor strength and electrical activity, physical activity, functional limitation, cognitive function, depression and anxiety, and biochemical measures of hypoxia, inflammation, oxidative stress, blood glucose, and lactate blood tests. The survey will follow the Standard Protocol Items for Randomized Trials guidelines, and the results will be reported according to the Consolidated Standards of Reporting Trials guidelines. Effects will be assessed based on the intent-to-treat data collected. Analysis of covariance will be used for the initial and final evaluations, with a significance level of 5%. Results and Conclusions: The results will show the effectiveness of rehabilitation in adults with post-COVID-19 sequelae.


Author(s):  
Sung-Kwan Oh ◽  
Da-Hye Son ◽  
Yu-Jin Kwon ◽  
Hye Sun Lee ◽  
Ji-Won Lee

We investigated the relationship between the basal metabolic rate (BMR) and muscle strength through measurement of handgrip strength. We conducted a cross-sectional study of a population representative of older Korean from the 2014–2016 Korean National Health and Nutrition Examination Survey. A total of 2512 community-dwelling men and women aged 65 years and older were included. The BMR was calculated with the Singapore equation and handgrip strength was measured using a digital dynamometer. The patients were categorized into handgrip strength quartiles and a weighted one-way analysis of variance (ANOVA) for continuous variables and a weighted chi-squared test for categorical variables were performed. Pearson, Spearman correlation analysis, univariate, and multivariate linear regression were performed. Analysis of covariance (ANCOVA) was also performed to determine the association between basal metabolic rate and handgrip strength quartiles after adjusting for confounding factors. The BMR increased according to handgrip strength quartile after adjusting for age, BMI, relative fat mass, comorbidity number, resistance exercise, aerobic physical activity, household income, educational level, smoking status, and alcohol ingestion in both sexes (p < 0.001). Handgrip strength has a positive association with the BMR in older Korean people. Therefore, muscle strength exercises should be considered for regulating the BMR in the older people.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Haruka Ito ◽  
Shohei Yamamoto ◽  
Manae Harada ◽  
Takaaki Watanabe ◽  
Yuta Suzuki ◽  
...  

Abstract Background and Aims In patients who undergo hemodialysis (HD), malnutrition is a frequent complication associated with higher risk of death, extended hospital stay, physical limitation, and decline of activities of daily living (ADL). Therefore, proper assessment for malnutrition in this population is important for effective disease management. The Global Leadership Initiative on Malnutrition (GLIM) released new criteria for diagnosing and grading malnutrition. Nevertheless, only very few studies have investigated malnutrition prevalence on the basis of the GLIM criteria in hemodialysis patients. Hence, the usefulness of the GLIM criteria’s application in hemodialysis patients remains unclear. The aims of this study were (1) to examine whether malnutrition diagnosed on the basis of the GLIM criteria will produce equivalent results with that diagnosed with the use of existing nutritional indicators and (2) to evaluate the association between the GLIM criteria and decline of physical function and ADL in Japanese patients on HD. Method This cross-sectional study included a total of 185 outpatients who undergo HD three times a week. We measured the existing nutritional indicators (GNRI, MNA-SF, phase angle, mid-arm muscle circumference, and calf circumference), physical function (Fried Scale, handgrip strength, usual gait speed, Short Physical Performance Battery, and physical activity), and ADL status (cumulative score of Barthel Index and instrumental ADL). On the basis of the GLIM criteria, the patients were classified into two groups (no malnutrition and malnutrition). In addition, in case of nutritional risk, nutritional assessment was performed by evaluation of the phenotypic (unintentional weight loss, low BMI, and/or reduced muscle mass) and etiologic (reduced intake or assimilation and/or inflammatory response) factors. Malnutrition was diagnosed if a patient has one or more of these items. The analysis of covariance (ANCOVA) was performed to examine the association between the GLIM criteria and existing nutritional indicators, physical function, and ADL status. Results Malnutrition was diagnosed in 41.1% of the participants based on the GLIM criteria. In contrast, on the basis of the existing nutritional indicators (GNRI, MNA-SF, phase angle, mid-arm muscle circumference, and calf circumference), malnutrition was diagnosed in 22.2%, 58.3%, 48.6%, 57.9%, and 54.6%, respectively. The ANCOVA results, adjusted for the patient’s characteristics, revealed that the malnutrition group had significantly lower score than the non-malnutrition group in the existing nutritional indicators (all P &lt; 0.001) (Figure). Furthermore, the malnutrition group had significantly higher Fried Scale scores, lower handgrip strength results, and lower ADL status than the non-malnutrition group, even after potential confounder adjustment (all P &lt; 0.05). Conclusion The GLIM criteria could be one of the useful tools for screening the risk of malnutrition, frailty, lower handgrip strength, and lower ADL status in patients who undergo HD.


Author(s):  
Jinkyung Cho ◽  
Inhwan Lee ◽  
Dong-Ho Park ◽  
Hyo-Bum Kwak ◽  
Kisuk Min

Although low socioeconomic status (SES) and decreased muscle strength have been found to be associated with the risk factors of non-alcoholic fatty liver disease (NAFLD), including insulin resistance, obesity, and metabolic syndrome, the associations among SES, muscle strength, and NAFLD are still unclear. We aimed to investigate the combined effect of SES and relative handgrip strength (HGS) on the risk of NAFLD in middle-aged adults. Data from 5272 middle-aged adults who participated in the Korea National Health and Nutrition Examination Surveys (KNHANES) from 2014–2018 were analyzed. NAFLD was defined using the hepatic steatosis index (HSI) > 36 and the comprehensive NAFLD score (CNS) ≥ 40 in the absence of other causes of liver disease. SES was based on a self-reported questionnaire. Overall, individuals with low SES (odds ratio (OR) = 1.703, 95% confidence interval (CI): 1.424–2.037, p < 0.001) or low HGS (OR = 12.161, 95% CI: 9.548–15.488, p < 0.001) had a significantly higher risk of NAFLD. The joint association analysis showed that a low SES combined with a low HGS (OR = 2.479, 95% CI: 1.351–4.549, p = 0.003) further significantly increased the risk of NAFLD when adjusted for all the covariates, compared with individuals with a high SES and a high HGS (OR = 1). The current findings suggest that both low SES and low HGS were independently and synergistically associated with an increased risk of NAFLD in middle-aged Korean adults.


Author(s):  
Chisato Hayashi ◽  
Soshiro Ogata ◽  
Tadashi Okano ◽  
Hiromitsu Toyoda ◽  
Sonoe Mashino

Abstract Background The effects of group exercise on the physical function of community-dwelling older adults remain unclear. The changes in lower extremity muscle strength, timed up and go (TUG) time, and the motor fitness scale (MFS), over time, among older adults who expressed a willingness to participate in community-based physical exercise groups, were determined using multilevel modelling. Methods We analyzed data of 2407 older adults between April 2010 and December 2019 from the registry of physical tests of community-based physical exercise groups. We conducted a retrospective cohort study to assess the effect of physical exercise on lower extremity muscle strength, TUG time, and MFS scores. The durations of the exercises were evaluated by frequency of physical test’s participate. Results A deterioration in lower extremity muscle strength was found in the short-term participant group only. However, in the mid-term and long-term participation groups, lower extremity muscle strength showed a trend of improvement. The TUG time and the MFS score were negatively correlated with increasing age in both groups divided by the duration of participation. However, there was a slower rate of deterioration in the long-term participation group. Discussion Lower extremity muscle strength, TUG time, and MFS scores decline with increasing age and there were differences in the slope of deterioration that depended on the duration of participation in community-based group exercise. Conclusion Participation in group exercise improved lower extremity muscle strength, TUG time, and MFS scores of older adults living in a community. The positive effects of group exercise were dependent on long-term participation.


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