Structure and clinical features of patients with acute appendicitis in infectious hospital

2021 ◽  
pp. 11-19
Author(s):  
V. P. Zemlyanoy ◽  
B. V. Sigua ◽  
V. A. Melnikov ◽  
M. M. Nakhumov ◽  
Yu. V. Letina
Keyword(s):  
Infectious Disease ◽  
Acute Appendicitis ◽  
Infectious Diseases ◽  
Clinical Features ◽  
Medical Records ◽  
Comparison Group ◽  
Surgical Patients ◽  
Group Iii ◽  
Group I ◽  
Hospital Patients

The results of the analysis of medical records of 148 patients with acute appendicitis who were treated in the surgical departments of an infectious diseases hospital and in a general surgical hospital are presented. The patients were divided into 3 groups: I (main) — patients with a confirmed infectious disease, II (occult) — patients with excluded infectious disease, III (comparison group) — patients of a general surgical hospital. Patients treated in an infectious diseases hospital were admitted mainly within 24 hours from the onset of the disease, while patients with a general surgical profile — in the interval from 6 to 24 hours from the onset of symptoms. In the structure of morphological forms of acute appendicitis in infectious patients, gangrenous appendicitis prevailed, and phlegmonous appendicitis among general surgical patients. Peritonitis, which is the most frequent complication of acute appendicitis, was registered in group I in 53 (96,4 %) cases, in group II in 35 (71,4 %) cases, and in group III in 16 (36,4 %) cases, moreover, the patients of the infectious diseases hospital predominantly developed purulent forms, and the patients of the general surgical hospital developed serous peritonitis.

scholarly journals Malformations of Cortical Development, Cognitive Involvementand Epilepsy: A Single Institution Experience in 19 Young Patients

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 637
Author(s):  
Valeria Venti ◽  
Maria Chiara Consentino ◽  
Pierluigi Smilari ◽  
Filippo Greco ◽  
Claudia Francesca Oliva ◽  
...  
Keyword(s):  
Clinical Features ◽  
Cortical Development ◽  
Young Patients ◽  
Cortical Dysplasia ◽  
Drug Resistant ◽  
Malformations Of Cortical Development ◽  
Group Iii ◽  
Group I ◽  
Cognitive Involvement ◽  
Group Ii

Background. Malformations of cortical development (MCD) include a wide range of congenital disorders mostly causing severe cognitive dysfunction and epilepsy. Objective: to report on clinical features including cognitive involvement, epileptic seizures with response to antiseizure medications, comorbidities in young patients affected by MCD and followed in a single tertiary hospital. Patients and methods: A retrospective review of the medical records and magnetic resonance images (MRI) of 19 young patients with an age ranging between eight days and fifteen years affected by MCD and admitted to Pediatrics Department University of Catania, Italy from October 2009 and October 2020 were selected. Patients were distinguished in three groups following the Barcovich et al. 2012 classification for MCD: 4 (21%) in Group I; 8 (42%) in Group II; and, and 7 (37%) in Group III. Clinical features and MRI of the patients including cognitive involvement, epilepsy type and response to drugs treatment were analyzed. Results: In Group I, two patients showed cortical dysplasia and two dysembryoplastic neuroepithelial tumors plus focal cortical dysplasia; developmental delay/intellectual disability (DD/ID) was severe in one, moderate in one and absent in two; the type of seizures was in all the cases focal to bilateral tonic-clonic (FBTCs), and drug resistant was found in one case. In Group II, three patients showed neuronal hetero-topias and five had pachygyria-lissencephaly: DD/ID was severe in four, moderate in two, and absent in two; the type of seizure was focal (FS) in five, focal to bilateral tonic-clonic (FBTCs) in two, infantile spasms (IS) in one, and drug resistant was found in three. In Group III, six showed polymicrogyria and one schizencephaly: DD/ID was found severe in five, moderate in two, and the type of seizure was focal (FS) in five, FBTCS in two, and drug resistance was found in three.

scholarly journals Infectious Diseases and Vaccination Strategies: How to Protect the “Unprotectable”?

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Elena Bozzola ◽  
Mauro Bozzola ◽  
Valeria Calcaterra ◽  
Salvatore Barberi ◽  
Alberto Villani
Keyword(s):  
Infectious Disease ◽  
At Risk ◽  
Infectious Diseases ◽  
Medical Records ◽  
Morbidity And Mortality ◽  
Childhood Immunization ◽  
Household Contacts ◽  
Vaccination Strategies ◽  
Immunization Strategies ◽  
Complicated Course

Introduction. The circulation of infectious diseases puts small infants too young to be vaccinated at risk of morbidity and mortality, often requiring prolonged hospitalization. Material and Methods. We have reviewed the medical records of children not eligible for vaccination because of age, admitted to hospital for pertussis, measles, or varicella from February 1, 2010, till February 1, 2012. Results. Of the case records scrutinized, 21 were hospitalized for pertussis, 18 for measles, and 32 for varicella. Out of them, 42%, 66%, and 78% diagnosed with, respectively, pertussis, measles, and varicella had a complicated course of the disease. Discussion. To avoid infectious disease circulation, childhood immunization strategies should be adopted, such as vaccination of healthcare givers, adult household contacts, and parents planning to have, or who have had, a newborn baby.

scholarly journals CHRONIC GASTRITIS CLINICAL FEATURES AND STOMACH FUNCTIONAL STATE DURING NONSTEROIDAL ANTI-INFLAMMATORY DRUGS ADMINISTRATION IN PATIENTS WITH OSTEOARTHRITIS

2016 ◽  
Vol 5 ◽  
pp. 17-22
Author(s):  
Maxim Zak ◽  
Lyudmila Pasiyeshvili
Keyword(s):  
Protective Factors ◽  
Atrophic Gastritis ◽  
Clinical Features ◽  
Chronic Gastritis ◽  
Group Iii ◽  
Group I ◽  
Gastric Contents ◽  
Inflammatory Drugs ◽  
Group Ii ◽  
Selective Nsaid

Aim. Determination of chronic gastritis clinical features and stomach functional state during nonsteroidal anti-inflammatory drugs (NSAID) administration in patients with osteoarthritis (OA). Materials and methods. 122 patients with OA and verified chronic gastritis (CG) (50 males and 72 females) aged 42 to 64 years (mean age – 49.65±3.51) were observed. Depending on gastritis morphological form, patients were divided into 2 groups: 54 patients with OA in combination with non-atrophic gastritis (NAG) were included into the group I, 68 patients with OA in combination with atrophic gastritis (AG) – into group II. 40 patients with OA without concomitant gastroduodenal pathology in anamnesis were included into the group III. All patients obtained selective NSAID for OA treatment: Meloxicam 15 mg daily or Nimesulide 200 mg daily. The control group was formed by 20 persons, which were found to be healthy after a complex examination. Stomach acid-forming function was investigated using esophageal pH monitoring. In the gastric contents, which obtained by aspiration, concentration of sialic acids glycoproteins, fucose, and hexosamines was determined. Results. Clinical picture of NSAID gastropathy at NAG characterized by abdominal pain of varying intensity and not associated with eating, but in patients with AG severity and discomfort symptoms dominated over weakly expressed pain syndrome. As a result of NSAID, in the group I dyspepsia developed in 31 (57.4 %), and erosive gastropathy developed in 9 (16.7 %) patients. In the group II, erosive gastropathy and dyspepsia were observed in 15 (22.1%) and in 35 (51.5 %) patients, respectively. In the group III, erosive gastropathy was observed 3.3 times (c2=84.33; р=0.009) and 4.4 times (c2=36.78; р=0.002) less than in groups I and II, respectively. In 25% patients of the group I after NSAID therapy intragastric pH increased from normacid to hyperacid status. In the group II, NSAID administration led to stomach mucosal (SM) protective factors depletion, which was observed in 73.3 % and in 28.6 % of patients with erosive gastropathy and NSAID-associated dyspepsia, respectively. At AG with erosive gastropathy, unlike NAG, several protective factors simultaneous reduction was observed. Coonclusion. In anamnesis, CG factor at selective NSAID administration (Meloxicam and Nimesulide) in relation to OA significantly increases the risk of erosive gastropathy, compared with patients without CG in anamnesis. At OA NSAID administration in patients with NAG led to gastric contents acidification and in patients with AG – to SM protective factors depletion (glycoprotein, fucose, and hexosamine).

scholarly journals Morphological signs of the effectiveness of application sorbent in the treatment of purulent wounds (experimental study)

Morphologia ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 7-15
Author(s):  
O. O. Bilyayeva ◽  
O. O. Dyadyk ◽  
V. I. Zaritsʹka ◽  
Ye. Ye. Kryzhevskyi
Keyword(s):  
Wound Healing ◽  
Comparison Group ◽  
Morphological Changes ◽  
Main Group ◽  
Group Iii ◽  
Group I ◽  
Purulent Wounds ◽  
Comparison Groups ◽  
New Generation ◽  
Connective Tissue Repair

Objective. To prove experimentally the effectiveness of a new generation of application sorbent by studying the morphological changes during the wound process. Methods. Depending on the drug used to treat purulent wounds, we divided the animals into three groups. In the main group (group I) the study was performed on 20 rats, they used an application sorbent, which includes aerosil with immobilization on its matrix ornidazole (Patent of Ukraine for utility model № 115228). The comparison group (group II) consisted of 10 rats, which used the known sorbent "Gentaxan", which includes: gentamicin sulfate, L-tryptophan and zinc sulfate. The comparison group (group III) was 10 rats. In this group for the treatment of purulent wounds used 10% sodium chloride solution, followed by a transition to ointment "Levomekol", which includes chloramphenicol and methyluracil. Results. The results of the study show that in the main group already on the seventh day in comparison with the comparison groups was found granulation tissue with a large number of newly formed vessels of the microcirculatory tract and pronounced proliferation of fibroblasts, indicating acceleration of wound healing. In the comparison groups, the regeneration process was slower. Conclusion. Pathomorphological examination revealed that drugs with sorption properties contribute to a faster reduction of edema and inflammation, and treatment with application sorbent used in the main group, significantly accelerates the processes of connective tissue repair and wound epithelization, ie accelerates wound healing processes with comparison groups.

scholarly journals The surgical correction of refractory venous trophic ulcers

2021 ◽  
pp. 38-46
Author(s):  
S. E. Katorkin ◽  
M. J. Kushnarchuk ◽  
M. A. Melnikov ◽  
A. A. Zhukov ◽  
P. F. Kravtsov ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Comparison Group ◽  
Complete Healing ◽  
Long Term Results ◽  
Group Iii ◽  
Results Of Treatment ◽  
Group I ◽  
Group Ii ◽  
Shave Therapy

Objectives. To study the effectiveness of layered dermatolipectomy and endoscopic fasciotomy in the surgical treatment of refractory venous trophic ulcers.Materials and methods. Patients (n = 105) of the C6 clinical class underwent crossectomy and short stripping. In group I (n = 35), free autodermoplasty of trophic ulcers with a perforated flap was performed. In group II (n = 36), shave therapy and autodermoplasty were performed. In group IIІ (n = 34), fasciotomy, shave therapy and autodermoplasty were performed. Long-term results of treatment were studied in the period from 1 to 12 months.Results. Complete healing of venous trophic ulcers was observed in group I at 49,4 ± 7,2, in II – at 31,4 ± 4,7, in III – at 32,1 ± 3,6 days сутки (t1-2 = 2,09; p1-2 = 0,049; t1-3 = 2,24; p1-3 = 0,024; t2-3 = 0,03; p2-3 = 0,763). Full engraftment of an autograft graft was recorded in 7 (19,4 %) patients of group I, in 27 (77,1 %) cases in group II and in 27 (79,4 %) patients of comparison group III (χ21-2 = 23,674; p1-2 = 0,001; χ21-3 = 25,173; p1-3 = χ22-3 = 0,052; p2-3 = 0,826).Conclusion. Layered dermatolipectomy with autodermoplasty and endoscopic decompression fasciotomy is an effective method for the treatment of persistent refractory venous trophic ulcers.

Improved Outcome for Patients With Middle Ear Rhabdomyosarcoma: A Children’s Oncology Group Study

2001 ◽  
Vol 19 (12) ◽  
pp. 3073-3079 ◽  
Author(s):  
Douglas S. Hawkins ◽  
James R. Anderson ◽  
Charles N. Paidas ◽  
Moody D. Wharam ◽  
Stephen J. Qualman ◽  
...  
Keyword(s):  
Clinical Features ◽  
Middle Ear ◽  
Demographic Data ◽  
Clinical Group ◽  
Nodal Metastases ◽  
Pilot Studies ◽  
Group Iii ◽  
Tumor Invasiveness ◽  
Group I ◽  
A Site

PURPOSE: The goal of this study was to define the clinical features and optimal therapy for children and adolescents with middle ear (ME) rhabdomyosarcoma (RMS). PATIENTS AND METHODS: We reviewed demographic data, clinical features, therapy (including chemotherapy, surgery, and radiation), and outcome for the 179 eligible patients with ME RMS who were enrolled onto Intergroup Rhabdomyosarcoma Studies (IRS) I through IV or pilot studies between November 1972 and December 1997. RESULTS: Most patients were younger than 10 years old (90%), and 63% were male. Because of the parameningeal location, most tumors were not resected before chemotherapy (group I, < 1%; group II, 4%; group III, 84%; group IV, 12%). Although most tumors were locally invasive (T2, 89%), the majority were small (≤ 5 cm, 66%), lacked nodal metastases (N0, 86%), and had embryonal histology (85%). The 5-year failure-free survival (FFS) and overall survival (OS) estimates were 67% and 72%, respectively. Both FFS and OS improved significantly over the course of IRS I through IV (3-year FFS and OS: IRS-I, 42% and 42%; IRS-II, 70% and 74%; IRS-III, 65% and 72%; IRS-IV pilot, 81% and 96%; IRS-IV, 88% and 88%, P < .001). Lower clinical group or stage and smaller tumor size were associated with better outcome. Age, sex, tumor invasiveness, and nodal metastases were not predictive of outcome. CONCLUSION: Patients with ME RMS generally present with small, unresectable, invasive tumors at a site traditionally considered prognostically unfavorable. Nevertheless, such patients have benefited markedly from improvements in multimodal, risk-based therapy during the course of IRS I through IV, and with contemporary therapy, most are cured.

scholarly journals The diagnosis of acute appendicitis in pregnant versus non-pregnant women: A comparative study

2016 ◽  
Vol 62 (7) ◽  
pp. 622-627 ◽  
Author(s):  
Abbas Aras ◽  
Erbil Karaman ◽  
Çağhan Pekşen ◽  
Remzi Kızıltan ◽  
Mehmet Çetin Kotan
Keyword(s):  
Retrospective Study ◽  
Acute Appendicitis ◽  
Comparative Study ◽  
Hospital Stay ◽  
Pregnant Women ◽  
Medical Records ◽  
Diagnostic Modality ◽  
Group I ◽  
Group Ii ◽  
Careful Assessment

Summary Objective: To investigate whether the diagnosis of acute appendicitis is affected by pregnancy or not. Method: A retrospective study with the analysis of the medical records of all women suspected of having appendicitis who underwent appendectomy at our hospital between June 2010 and March 2015 were reviewed. The patients were divided into two groups according to whether they were pregnant or not during the surgery: group I, pregnant women, and group II, non-pregnant women. Results: During the study period, 38 pregnant women and 169 non-pregnant women underwent appendectomy. The time from admission to the operation was not statistically different (2.17±1.47 days in group I vs. 1.98±1.66 day in group II; p=0.288). The pregnant group had longer hospital stay than the non-pregnant group (p=0.04). Ultrasonography (USG) was used as the first diagnostic modality in 36/38 patients in group I and 161/169 in group II. The non-visualized appendix on ultrasound was seen in 17 patients in group I and 51 patients in group II, which was not statistically different. Sensitivity and specificity of USG in diagnosis of acute appendicitis were 61.29 and 80.00% in group I, and 93.0 and 31.6% in group II, respectively. Conclusion: Although the diagnosis of appendicitis in pregnant women is not delayed, careful assessment of these patients suspected of having appendicitis should be encouraged when USG examination is normal or nondiagnostic.

Clinical features of hepatic metastasis in patients with ovarian cancer

2005 ◽  
Vol 15 (1) ◽  
pp. 26-31 ◽  
Author(s):  
V. Loizzi ◽  
C. Rossi ◽  
G. Cormio ◽  
A. Cazzolla ◽  
D. Altomare ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Clinical Features ◽  
Hepatic Metastasis ◽  
Performance Status ◽  
Cell Type ◽  
Group Iii ◽  
Cancer Group ◽  
Group I ◽  
Platinum Based Chemotherapy ◽  
Group Ii

The purpose of this study was to investigate the clinical features of hepatic metastasis in patients with epithelial ovarian cancer. From 1998 to 2002, all women with hepatic metastasis from ovarian cancer were identified at the University of Bari. Twenty-nine patients identified included one having stage IIC, one stage IIIA, two stage IIIB, 17 stage IIIC, and eight stage IVB. Eight women had hepatic metastasis at the time of the diagnosis of ovarian cancer (group I), 10 patients had hepatic metastasis as first recurrence (group II), and 11 (group III) as a second relapse. The median survival from the time of liver metastasis diagnosis was 19 months in group I patients, 24 months in group II patients, and 10 months in group III patients. No statistical differences in survival were seen among the three groups (P = 0.7). Cell type, performance status at the time of the primary tumor diagnosis, number of hepatic lesions, the presence of other sites of disease at the time of hepatic metastasis, and platinum-based chemotherapy were significantly related to survival. Better performance status, serous cell-type tumor, single hepatic lesion, the absence of other sites of disease, and platinum-based chemotherapy are good prognostic factors.

scholarly journals OPTIMIZATION OF VITAMIN D LEVEL WITH AN ASSESSMENT OF THE EFFECT ON THE MORPHOFUNCTIONAL STATE OF THE MYOCARDIUM IN PATIENTS WITH CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION

2018 ◽  
pp. 54-61
Author(s):  
A. S. Morgol ◽  
L. V. Yakubova
Keyword(s):  
Heart Failure ◽  
Vitamin D ◽  
Chronic Heart Failure ◽  
Ejection Fraction ◽  
Thoracic Aorta ◽  
Comparison Group ◽  
Preserved Ejection Fraction ◽  
Group Iii ◽  
Group I ◽  
Aorta Diameter

Objective: to evaluate the effectiveness of intake of vitamin D-containing drugs at different dose modes with an assessment of 25-hydroxy-cholecalciferol (25(ОН)D) level and echocardiography parameters in patients with chronic heart failure with preserved ejection fraction (CHF-PEF). Material and methods. 82 patients with CHF-PEF and D-hypovitaminosis were divided into 4 groups: group I (n = 26) - received Cholecalciferol 2000 IU/day, group II (n = 16) - 1000 IU/day, group III (n = 23) - a vitamin D-containing food additive, the comparison group (n = 17) - underwent only complex pathogenetic CHF therapy. Results. The 25(OH)D level in group I reached the optimal level in 84.6 % persons, in group II - in 56.2 % (p = 0.04), in group III - in 69.6 %, in the comparison group in 29.4 % (p = 0.0006). The level of 25(OH)D was negatively associated with the thoracic aorta diameter and end-diastolic volume of the left ventricle (EDV-LV). Conclusion. Optimization of 25(OH)D has a positive effect on the thoracic aorta diameter, anterior-posterior size of the left atrium and EDV-LV.

scholarly journals Ozonotherapy influence on hormonal status of pregnant women of older reproductive age

2019 ◽  
Vol 36 (4) ◽  
pp. 27-32
Author(s):  
R. B. Safarova
Keyword(s):  
Pregnant Women ◽  
Comparison Group ◽  
Preventive Therapy ◽  
Main Group ◽  
Reproductive Age ◽  
Control Group ◽  
Hormonal Status ◽  
Group Iii ◽  
Group I ◽  
Medical Ozone

Aim. To study the hormonal status in pregnant women of older reproductive age and estimate the influence of administration of medical ozone on the course of pregnancy. Materials and methods. Ninety pregnant women aged 3544 years were examined over the period from 2013 to 2015. They were randomized by their age, social factors, associated gynecological and extragenital diseases. The main group (group I) joined 30 patients, the group of comparison (group II) 30 patients and the control (group III) 30 patients. All the patients underwent clinical and laboratory investigations according to the existing standards of obstetric examination. In the main group, complex treatment included therapy with medical ozone. In the comparison group, a standard medico-preventive therapy by the protocol №05 (20.02.2014 MH of AR) was implemented. In the control group, estrogen indices were studied in dynamics. Results. Pregnant women aged 35 years and older have an unfavorable background of extragenital and gynecological pathology that is confirmed by hormonal background. Conclusions. Planning of pregnancy, timely prevention and correction of clinicolaboratory indices permit to reduce the frequency and severity of pregnancy and delivery complications and improve the perinatal indices among patients of this age group.

Sign in / Sign up

Export Citation Format

Share Document