The influence of resource and saving technologies on the clinical parameters and morphological status of the blood of first-calf heifers of Holstein breed

2021 ◽  
pp. 13-18
Author(s):  
N. A. Fedoseeva ◽  
I. A. Timinskaya
Keyword(s):  
Red Blood Cells ◽  
Pulse Rate ◽  
Blood Cells ◽  
White Blood Cells ◽  
Winter Period ◽  
Clinical Parameters ◽  
Morphological Parameters ◽  
Holstein Breed ◽  
Group 2 ◽  
Group 1

The data on the clinical and morphological parameters of the blood of first-calf heifers of Holstein breed in the winter and summer periods of the year, which were housed by tie-up housing and free-stall housing (using resource and saving technology) methods have been presented in the article. It has been found that the clinical parameters in the studied groups of animals were within the physiological norm. In the winter period the body temperature and pulse rate of the first-calf heifers with free-stall housing (group 2) was higher than that of their herdmates with tie-up housing (group 1) by 0,2 °C or 0,5 %, and by 0,4 times/min or 0,6 %, respectively. In the summer period there was an increase in the pulse rate and respiration rate in the 2nd group of first-calf heifers by 0,6 times/ min or 0,9 % and 0,7 breaths/min or 2,9 %, respectively. Thus, in the experimental animals the clinical parameters were within the physiological norm, and the first-calf heifers contained in the free-stall housing were superior to the first-calf heifers contained in the tie-up housing method. The first-calf heifers of group 2 had a higher pulse rate and respiratory rate, which indicates higher metabolic processes in their body. The morphological parameters of the blood in the animals were within the physiological norm. However, in winter the content of red blood cells and white blood cells in animals of group 2 was higher than in group 1 herdmates by 0,2×10¹²/, or 3,8 % (P < 0,01) and by 0,4×10⁹/l or 6,1 % (P < 0,001), respectively. In the summer, the content of red blood cells increased in the first-calf heifers of the 1st group by 0,3×10¹²/l or 5,9 %, in the 2nd group by 0,9×10¹²/l or 17,0 % compared with the winter period. The increased content of white blood cells, red blood cells and hemoglobin, both in winter and in summer, indicates a higher metabolism of first-calf heifers housed in the free-stall housing method.

scholarly journals Association of Lower Genital Tract Inflammation With Objective Evidence of Endometritis

2000 ◽  
Vol 8 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Jeffrey F. Peipert ◽  
Roberta B. Ness ◽  
David E. Soper ◽  
Debra Bass
Keyword(s):  
Tract Infection ◽  
Blood Cells ◽  
Genital Tract ◽  
White Blood Cells ◽  
Genital Tract Infection ◽  
Lower Genital Tract ◽  
Objective Evidence ◽  
Group 2 ◽  
Upper Genital Tract Infection ◽  
Group 1

The purpose of this report is to evaluate the association between lower genital tract inflammation and objectively diagnosed endometritis. We analyzed the first 157 patients enrolled in the PEACH study, a multicenter randomized clinical trial designed to compare the effectiveness of outpatient and inpatient therapy for PID. Women less than 38 years of age, who presented with a history of pelvic discomfort for 30 days or less and who were found to have pelvic organ tenderness (uterine or adnexal tenderness) on bimanual examination, were initially invited to participate. After recruitment of the first 58 patients (group 1) we added the presence of leukorrhea, mucopurulent cervicitis, or untreated positive test forN. gonorrhoeaeorC. trachomatisto the inclusion criteria (group 2, N = 99). We compared rates of endometritis in the two groups and calculated the sensitivity, specificity, and predicted values of the presence of white blood cells in the vaginal wet preparation. The rate of upper genital tract infection in group 1 was 46.5% (27/58) compared to 49.5% (49/99) in group 2. Microbiologic evidence of eitherN. gonorrhoeaeorC. trachomatisincreased from 22.4% in group 1 to 38.3% in group 2. The presence of Vaginal white blood cells or mueopus has a high sensitivity (88.9%), but a low specificity (19.4%) for the diagnosis of upper genital-tract infection. Assessment of the lower genital tract for evidence of infection or inflammation is a valuable component of the diagnostic evaluation of pelvic inflammatory disease. The presence of either mucopus or vaginal white blood cells is a highly sensitive test for endometritis in patients with pelvic pain and tenderness. Infect. Dis. Obstet. Gynecol. 8:83–87, 2000.

Hematological condition of breeding bulls after a long winter period of operation in the conditions of the Udmurt Republic

2022 ◽  
pp. 67-73
Author(s):  
A. Abilov ◽  
A. Azhmyakov ◽  
I. Novgorodova ◽  
N. Bogolyubova
Keyword(s):  
Red Blood Cells ◽  
Reference Values ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Winter Period ◽  
Black And White ◽  
Significant Difference ◽  
White Breed ◽  
Udmurt Republic

Purpose: to study hematological parameters of blood in bulls-producers of dairy breeds on the day of semen collection in the Udmurt Republic after a long winter period of operation, depending on the breeds, age and place of selection.Materials and methods. The work was performed at the Federal Research Center for Animal Husbandry named after Academy Member L. K. Ernst on the basis of AO "Udmurtplem" of the Udmurt Republic in the period from 2020 to 2021 on dairy bulls (n=20) aged 15-69 months, including a purebred Holstein breed of domestic selection (n=6), a Holstein black-and-white breed of European selection (the Netherlands, n=6), a black-and-white breed with blood transfusion on Holsteins on at the level of 94-98% (n=8). The content of white blood cells, red blood cells, hemoglobin and hematocrit, depending on age and breed, was studied on the ABC VET hematological analyzer on the day of taking the seed.Results. It was found that on average, in 20 bulls aged 15-69 months, the level of white blood cells was at the level of reference values of 8.8±0.25 x 109/l, red blood cells 10.3 x 1012/l, which is 50% more than the reference values. The concentration of hemoglobin is 128.0±2.92 g/l, hematocrit is on average 54.3%, with a norm of 24-46%. Breeding bulls at a reliable level, differing in age, showed that some animals had high indicators for red blood cells of 10.3±0.26 x 102, for hematocrit of 54.3% against 24-46% of reference values. Also, according to hematological indicators, there was a tendency to increase the concentration of hemoglobin and hematocrit in European-bred bulls.Conclusion. The study of the variability in hematological parameters depending on the selection showed that there is no significant difference in leukocytes and all indicators are at the level of reference values, and in erythrocytes more than 50% than the highest indicators. The highest hemoglobin values were at the level of 141-156 g/l instead of 128 g/l according to the highest reference values. Hematocrit also showed high max values in all groups in comparison with the reference values of 59-66% versus 46% in the norm. It is necessary when analyzing hematological blood parameters in addition to the average statistical indicators (M+m) also, monitor the variability (min-max) in order to obtain more objective information.

scholarly journals Comparative evaluation of blood salvage techniques in patients undergoing cardiac surgery with cardiopulmonary bypass

Perfusion ◽  
2017 ◽  
Vol 33 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Serdar Gunaydin ◽  
Craig Robertson ◽  
Ali Baran Budak ◽  
Terence Gourlay
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Blood Cells ◽  
Randomized Study ◽  
White Blood Cells ◽  
Cell Saver ◽  
Blood Salvage ◽  
Group 2 ◽  
Intraoperative Blood Salvage ◽  
Group 1

Background: The primary objective of this study was to test and compare the efficacy of currently available intraoperative blood salvage systems via a demonstration of the level of increase in percentage concentration of red blood cells (RBC), white blood cells 9WBC) and platelets (Plt) in the end product. Methods: In a prospective, randomized study, data of 80 patients undergoing elective cardiac surgery with cardiopulmonary bypass in a 6-month period was collected, of which the volume aspirated from the surgical field was processed by either the HemoSep Novel Collection Bag (Advancis Surgical, Kirkby-in-Ashfield, Notts, UK) (N=40) (Group 1) or a cell- saver (C.A.T.S Plus Autotransfusion System, Fresenius Kabi, Bad Homburg, Germany) (N=40) (Group 2). Results: Hematocrit levels increased from 23.05%±2.7 to 43.02%±12 in Group 1 and from 24.5±2 up to 55.2±9 in Group 2 (p=0.013). The mean number of platelets rose to 225200±47000 from 116400 ±40000 in the HemoSep and decreased from 125200±25000 to 96500±30000 in the cell-saver group (p=0.00001). The leukocyte count was concentrated significantly better in Group 1 (from 10100±4300 to 18120±7000; p=0.001). IL-6 levels (pg/dL) decreased from 223±47 to 83±21 in Group 1 and from 219±40 to 200±40 in Group 2 (p=0.001). Fibrinogen was protected significantly better in the HemoSep group (from 185±35 to 455±45; p=0.004). Conclusions: Intraoperative blood salvage systems functioned properly and the resultant blood product was superior in terms of red blood cell species. The HemoSep group had significantly better platelet and leukocyte concentrations and fibrinogen content.

scholarly journals Influence of Heat Stress on Development of Chick Embryo (in ovo)

2012 ◽  
Vol 6 (1) ◽  
pp. 10-18
Author(s):  
Ahlam Al-Kharusi ◽  
Sumaya Al-Mahrouqi ◽  
Esmail K. Shubber
Keyword(s):  
Heat Stress ◽  
Chick Embryo ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Genome Stability ◽  
Control Group ◽  
Poultry Production ◽  
In Ovo ◽  
Group 2 ◽  
Group 1

The present study was conducted to determine the adverse effects of high incubation temperature on growth, development and genome stability of broiler chick embryo in ovo). One hundred twenty broiler eggs from Cobb Company, USA were weighted and divided into two groups. The first group was incubated at 37oC ± 0.5oC, and the second group was incubated at 41oC ± 0.5oC from 0 to 18th day. Starting on day 4th and every other day; three eggs from each group were examined following performed measurements as weight of eggs post incubation, embryo, yolk, and egg shell for measuring growth index. Blood smear was also prepared for counting heterophiles, and lymphocytes to determine H/L ratio. Micronucleus formation and presence of binucleated red blood cells were investigated as genome stability parameters, in 2000 cells. Significant reduction (P<0.01) in growth indices was observed in embryos grown at 41oC compared to those grown at 37oC ± 0.5oC. Reduction in H/L ratio was statistically significant (p≤0.01) in embryos of 2nd group comparing to 1st group embryos. Blood of embryo from heat stress group group (2) showed Red blood cells with micronuclei and binucleated cells while no such phenomenon could be seen in embryos from control group group (1). These results suggested that heat stress is influencing cell division at telophase and induces chromosomal damage. 88% of chicks from group (1) were hatched on day 21st; only 18% of chicks from group (2) were hatched lately on day 23rd, while the others were found dead. These results indicate that heat stress not only adversely affects growth and development of embryo stem cells but also induces genome instability which intern resulted in poultry production losses.

Erythropoietin Use In Patients with AML or Undergoing Allogeneic HSCT Significantly Improves Quality of Life and Reduces Red Blood Cells and Platelets Transfusions without Any Survival Effect.

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 3810-3810
Author(s):  
Mauricette Michallet ◽  
Karine Goldet ◽  
Stephane Morisset ◽  
Mohamad Sobh ◽  
Youcef Chelghoum ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Red Blood Cells ◽  
Median Time ◽  
Blood Cells ◽  
Positive Impact ◽  
Group 2 ◽  
Group 1

Abstract Abstract 3810 Introduction: Despite frequent anemia and multiple transfusions during AML chemotherapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT), recommendations and marketing authorization for erythropoietin (EPO) use are still missing. In the current prospective study, as primary objective, we evaluated the effect of EPO on patient's quality of life (QOL). Secondary objective was hemoglobin (Hb) recovery. In addition, a paired matched analysis using similar population was conducted to compare platelets (Pt) and red blood cells (RBC) transfusion number. Materials and methods: We included adult patients with Hb level ≤11g/dl induced by 1, 2 or 3 consolidation chemotherapy for AML in complete remission (CR) (group 1); or by allo-HSCT for any hematological disease (group 2). EPO was administered Sc. once per week during a maximum period of 6 months: for group 1, ARANESP® 150μg; for group 2, NEORECORMON® 30000IU; Hb level was monitored every week. Injections were stopped once the Hb level reached 12g/dl without any transfusion. If after 4 injections, no improvement was observed, doses were doubled, and if after 8 injections, no improvement was observed, patient was taken off-study for EPO inefficiency. The QOL was measured at baseline, at 1, 2, 3 and 6 months by the Functional Assessment of Cancer Therapy–Anemia (FACT–An). EPO responders patients were defined as having Hb level ≥12g/dl (EPO CR) or a ≥ 2g/dl increase [EPO partial response (EPO PR)] compared with baseline value without any transfusion requirement. The matching analysis took into account: sex, age, disease status, for the two groups, associated to cytogenetics, type of chemotherapy, sequential chemotherapy number for group 1, and diagnosis, conditioning, HSC source, number of previous transplants and GVHD for group 2. Results: Between April 2006 and December 2009, among 261 screened patients, 55 were included in group1 and 61 in group 2, patient characteristics for each group are summarized in Table1. Main exclusion criteria were EPO contra-indication and patient refusal. The median number of EPO injections/patient was 13 (3 – 24) in group1 and 8 (2 - 28) in group 2. For the global population (111 evaluable patients [52 group1 and 59 in group 2]), we have noticed a significant improvement of QOL during the 6 months follow-up according to FACT-An anemia (p=0.01). Despite a non-significant improvement for FACT-G, we observed a significant improvement in physical well-being (p<0.0001). There were 85 EPO CR (83% in group1 and 71% in group 2) and 3 (6%) EPO PR (only in group1). Among patients who reached the 6 months follow-up, 81% had a normal Hb level. Fourteen patients (13%) were withdrawn (6 in group1 and 8 in group 2) due to EPO inefficacy and 9 in group 2 for relapse or EPO related/unrelated serious adverse events (AEs). In group1: the median time to achieve an EPO CR was 34 days (17-67) after first consolidation and 41 days (12-67) after second consolidation (p=0.35). In group 2: the median time to achieve EPO CR was 39 days (14 - 180). After the pair-matched analysis, 44 patients in each group were matched with at least one case-control patient. When comparing RBC and Pt transfusions, there were 712 units and 751 units in the matched population versus 504 and 669 in the EPO population respectively [208 spared RBC (80 in group1, p=0.008 and 128 in group 2, p=0.004) and 100 spared Pt units (all in group1, p=0.001)]. The multivariate analysis studying different confounding factors on the cumulative incidence of EPO CR showed a significant positive impact of younger age (p=0.001) and intensive chemotherapy (p=0.03) in group1; and for group 2, the positive impact of Pt levels at baseline, the negative impact of female recipient and major ABO incompatibility. We did not find any significant difference in terms of overall (OS) and event free survival (EFS) between EPO and control groups. Conclusion: This prospective study showed a real benefit of EPO administration on QOL, an achievement of a normal Hb level and a significant spare of RBC and Pt transfusions. Young AML patients, male allo-HSCT recipient, ABO compatible pairs seem to be the best candidates to benefit from EPO administration, with low AEs and no impact on OS or EFS. A cost-effectiveness study is ongoing and results will be communicated. Disclosures: No relevant conflicts of interest to declare.

Influence of residual blood autotransfused from cardiopulmonary bypass circuit on clinical outcome after cardiac surgery

Perfusion ◽  
2005 ◽  
Vol 20 (2) ◽  
pp. 71-75 ◽  
Author(s):  
Edmundas Sirvinskas ◽  
Tadas Lenkutis ◽  
Laima Raliene ◽  
Audrone Veikutiene ◽  
Jolanta Vaskelyte ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Postoperative Period ◽  
Blood Cells ◽  
Heart Surgery ◽  
Early Postoperative Period ◽  
Group 3 ◽  
Group 2 ◽  
Residual Blood ◽  
Infective Complications ◽  
Group 1

Autotransfusion of the residual blood from the cardio-pulmonary bypass (CPB) circuit is considered to be one of the methods enabling reduction in the need for transfusion, the possible adverse effects of which are well known and documented. The aim of the study was to evaluate the effectiveness of the autologous autotrans-fusion of centrifuged red blood cells from the residual blood of the CPB circuit in patients following heart surgery. Three groups of patients who underwent heart surgery were examined. The first group (Group 1) consisted of 37 patients who received all of the residual blood in the bypass circuit after CPB (collected into sterile plastic bags) during the early postoperative period. The second group (Group 2) consisted of 45 patients who did not receive the residual blood following CPB. The third group (Group 3) consisted of 42 patients who underwent re-infusion of centrifuged red blood cells from the residual blood remaining in the CPB circuit during the early postoperative period. Hematocrit (Hct) values 12 hours after the operation were found to be higher in Group 3 compared with those of the first and the second groups (by 13.2% and 11.1%, respectively). Blood loss during the first 12 hours after the operation and during the time spent in the intensive care unit did not differ between the groups. The number of transfusions was significantly lower in Group 3 (28.57%) in comparison with that of Groups 1 and 2 (37.83% and 38.10%, respectively). The rate of infective complications in Group 3 was lower in comparison with both Group 1 and Group 2 (9.2% and 18.1%, respectively). The duration of in-hospital stay in Group 3 was 25.8% shorter than Group 1. We conclude that autotransfusion of centrifuged red blood cells processed from the residual blood of the CPB circuit after CPB was effective in increasing Hct values 12 hours postoperatively, reducing the need for donor blood product transfusions, the rate of infective complications and lenght of stay in hospital.

Evaluating the blood toxicity of functionalized graphene-arginine with anticancer drug ginsenoside Rh2 in balb/c mouse model with breast cancer

2022 ◽  
Author(s):  
Shervin Dokht Farhangfar ◽  
Farzaneh Fesahat ◽  
Sayed Mohsen Miresmaeili ◽  
Hadi Zare-Zardini
Keyword(s):  
Anticancer Drug ◽  
Blood Cells ◽  
White Blood Cells ◽  
Functionalized Graphene ◽  
Ginsenoside Rh2 ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Group 1 ◽  
Blood Factors

Background: Gensenoside Rh2 is an anticancer drug with low toxicity and stability in the body. The aim of this study was to evaluate the blood toxicity of functionalized graphene-arginine with anticancer drug ginsenoside Rh2 in balb/c mouse model with breast cancer. Materials and Methods: Graphene-Arginine (G-Arg) and Graphene-Arginine-ginsenoside Rh2 (G-Arg-Rh2) were synthesized using microwave method. For evaluation of blood toxicity, 32 mice with breast tumors were randomly divided into 4 groups: control (3mg/kg 6 mg / kg PBS sterile), group 1 (6 mg / kg ginsenoside), group 2 (3 mg / kg G-Arg), and group 3 (3 mg / kg G-Arg-Rh2). Treatment was done intravenously once every three days for 32 days. Finally, blood factors were also examined by sampling from the heart. Results: Complete functionalization was proven by FTIR and Raman. Examination of blood factors showed that white blood cells had a very small increase. Anova test showed significant difference among four groups in term of WBC count (p=0.016). Pair sample T test showed that there was significant difference between control and group 1(p=0.036) and control and group 2 (p=0.036). There was no significant difference between control and group 3 (p=0.051). Other blood factors had no significant difference among examined groups (p>0.05). Conclusion: Based on results, after treatment with all designed nanostructures, only white blood cells had a very small increase and inflammatory reactions were statistically similar in all groups. This indicates the high efficiency of designed drug.

scholarly journals Assessment of Sub Chronic Toxicity of Sonchus cornutus in Rats

2019 ◽  
pp. 1-8
Author(s):  
Hayat Mahgoub Farah ◽  
Abdel Rahim Mohamed El Hussein ◽  
Hassan Elsubki Khalid ◽  
Halima Mohamed Osman
Keyword(s):  
Aqueous Extract ◽  
Blood Cells ◽  
Biochemical Analysis ◽  
White Blood Cells ◽  
Clinical Signs ◽  
Albino Rats ◽  
Liver And Kidney ◽  
Group 2 ◽  
Wistar Albino Rats ◽  
Group 1

Aim: To assess the toxicity of the aqueous extract of Sonchus cornutus in Wistar albino rats. Methodology: The aqueous extract of Sonchus cornutus aerial part was administered orally to rats in group 2, 3 and 4 at a dose of 50, 500 and 2000 mg/ kg, respectively for four weeks whereas, group 1 was kept as a control. The animals were observed daily for clinical signs and mortality. Weekly, the weights of the animals were recorded, and blood samples were collected for haematological and biochemical analysis. Specimens of Liver and kidney were kept in 10% formalin for histopathology. Results: The results revealed that all the animals in the four groups survived. The extract had no adverse effects on haematology, biochemistry and histology of rats at doses of 50 and 500 mg/ kg. But dose 2000 mg/kg proved to have significant alteration in White blood cells (WBCs), Red blood cells (RBCs), Haemoglobin (Hb) and Packed cell volume (PCV). In addition, total protein, albumin, urea, creatinine, Alanin Transaminase (ALT), Asparate Transaminase (AST) were significantly (P<0.05) changed. These findings correlated with the histopathological changes on liver and kidney. Conclusion: The highest dose of S. cornutus aqueous extract (2000 mg/kg) was not fatal, but may have some toxic effects on liver and kidney.

scholarly journals STRESS-PROTECTIVE EFFECT OF SUCCINATE-CONTAINING DRUG ON THE LEUKOCYTE COMPOSITION OF RAT BLOOD UNDER THE INFLUENCE OF HYPOXIA

2021 ◽  
Vol 248 (4) ◽  
pp. 106-112
Author(s):  
L.Yu. Karpenko ◽  
◽  
F.I. Alistratova ◽  
A.I. Enukashvili ◽  
A.A. Bakhta ◽  
...  
Keyword(s):  
Blood Cells ◽  
White Blood Cells ◽  
The Body ◽  
Male Rats ◽  
Animal Blood ◽  
Protective Function ◽  
Group 3 ◽  
Group 2 ◽  
Group 1 ◽  
Intact Rats

The study of the dynamics of white blood cells in male rats under the conditions of normoxia and in the simulation of hypoxia before and after the use of the succinate-containing drug Cytoflavin ®was carried out. The animals were divided into three groups: two control groups of animals: group 1 – intact rats kept in standard vivarium conditions, and group 2, which were subjected to hourly hypoxic exposure, and group 3 - experimental animals subjected to daily training in a hypoxicator (O2-14%) and received the drug immediately before training. The multidirectional shifts characterizing the morphofunctional state of the white blood of rats under experimental conditions were determined. In group 2 animals, compared to group 3, there was a decrease in the number of white blood cells due to an increase in the pool of granulocyte cells, and an unchanged level of agranlocytes with a tendency to reduce the number of lymphocytes. In-group 2, compared with group 3, the change in the number of white blood cells and their subpopulation composition significantly differed from the control group 1, intact rats, and there was a decrease in the number of phagocytic mononuclears and an increase in granulocyte cells. The differences in the cellular composition of blood in group 2 animals from the data of group 3 are considered as the effect of the succinate-containing drug Cytoflavin ® on the preparation of the body for the implementation of the protective function under the influence of extreme factors and the stress of the body's resistance to load, since the nature of the redistribution of the leukocyte composition of blood in group 2 has a significant similarity in indicators with animals in group 3. The practical significance of the research is related to the search for new biologically active substances that optimally affect the ability of the animal body to adapt to conditions of low oxygen content. New data on the mechanism of redistribution of animal blood, which is realized under the action of the succinate-containing drug Cytoflavin ® in conditions of oxygen deficiency, can be used to study the regularities of the manifestation of an urgent adaptive effect.

scholarly journals Effect of Yeast (Saccharomyces cerevisiae) Enhanced with Selenium or Zinc on the Hematological Characteristics in Iraqi Does

2019 ◽  
Vol 12 (2) ◽  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Blood Cells ◽  
White Blood Cells ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Yeast Saccharomyces Cerevisiae ◽  
Previous Birth ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

This study was conducted to investigate the effect of yeast (Saccharomyces cerevisiae) enhanced with Selenium or Zinc on some hematological characteristics in the Iraqi female goats. The seventeen adult female goats 2-2.5 years old with average body weight (bw) 37.5 ± 2.5 kg that have at least one previous birth were used. The animals were randomly divided in to three groups, group 1 have 5 goats, group 2 and 3 have six goats. all doesss were fed same ration. Animals of group 1 (G1) were let without treatment which considered as a control group, Animals of group 2 (G2) was given yeast enriched with selenium (0.03 g/kg/bw), While Animals of group 3 (G3) were given yeast enriched with zinc (0.2 g/kg/bw). The animals were treated by dissolving the samples in 30 ml of distilled water and administered orally for 45 days. Blood samples were collected from the jugular vein during first day (first period), twelfth day (second period) fort- fifth day (third period) to carrying out blood tests. The results showed was significant increase (P≤0.05) in the count of the red blood cells, hemoglobin concentration and Hematocrit of second and third groups as compared with first group. While the second group was significant increase in the number of white blood cells compared with the first and third groups. From the results, it could be concluded that there synergistic effect of Saccharomyces cerevisiae with selenium or zinc may be attributed to improve some hematological aspects in does.

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