scholarly journals Assessment of Thyroid Cancer Risk After Cervical Computed Tomography: The Impact of Bismuth Shielding

2021 ◽  
Vol 10 (2) ◽  
pp. 70-74
Author(s):  
Hamid Ghaznavi ◽  
Zeinab Momeni ◽  
Sadegh Ghaderi
Keyword(s):  
Computed Tomography ◽  
Thyroid Cancer ◽  
Cancer Risk ◽  
Biological Effects ◽  
The Body ◽  
Male And Female ◽  
Thyroid Dose ◽  
Thyroid Cancer Risk ◽  
Bismuth Shielding ◽  
The Impact

Background: Computed tomography (CT) is vastly applied in X-ray procedures because of its high quality in detecting the anatomical structures of the body. However, it leads to an increase in patient dose, resulting in carcinogenesis. In the head and neck CT, the thyroid is the most important at-risk organ. The aim of this study was to estimate thyroid cancer risk in cervical CT with and without a bismuth shield. Materials and Methods: After obtaining permission from the authors, data related to the thyroid dose of patients undergoing cervical CT in the study by Santos et al (2019) were used, and then thyroid cancer risk was calculated for different ages at exposure in male and female patients using the biological effects of the ionizing radiation (BEIR) VII model. Results: Using bismuth shielding reduced thyroid dose by 37% and 39% in male and female phantoms, respectively. Thyroid cancer estimation demonstrated that the risk was nearly two-fold in females compared to males. Finally, bismuth shielding reduced 40% of cancer risk, and it decreased in both genders by increasing age at exposure. Conclusion: According to our findings, excess relative risk (ERR) up to 0.06% was associated with cervical CT. Although ERR amounts were low, the effect of radiation on thyroid cancer risk should not be neglected. Accordingly, it is suggested that future trials use bismuth shielding to reduce thyroid cancer risk.

Prediagnostic BMI and thyroid cancer incidence in the PLCO trial

2019 ◽  
Vol 15 (30) ◽  
pp. 3451-3456 ◽  
Author(s):  
Omar Abdel-Rahman
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Cox Regression ◽  
Complete Information ◽  
Study Enrollment ◽  
Thyroid Cancer Risk ◽  
History Of ◽  
The Impact ◽  
Thyroid Cancer Incidence ◽  
Bmi Trajectory

Aim: To assess the correlation between prediagnostic BMI and thyroid cancer risk within the prostate, lung, colorectal and ovary (PLCO) trial. Methods: PLCO trial participants without a history of thyroid cancer before study enrollment who have complete information about prediagnostic BMI were included. Multivariable Cox regression analyses were conducted to assess the impact of prediagnostic BMI on thyroid cancer risk. Results: Higher BMI at the time of the study enrollment was associated with a higher thyroid cancer risk (hazard ratio: 1.046; p < 0.01). Furthermore, compared with a normal to normal prediagnostic BMI trajectory, both normal to overweight as well as normal to obese trajectories were associated with a higher thyroid cancer risk (p = 0.04 and p = 0.03, respectively). Conclusion: Higher BMI at the time of study entry as well as an increasing prediagnostic BMI trajectory are associated with a higher thyroid cancer risk.

scholarly journals Thyroid Cancer Risk in Patients Undergoing 64 Slice Brain and Paranasal Sinuses Computed Tomography

2020 ◽  
Author(s):  
Hamid Ghaznavi
Keyword(s):  
Computed Tomography ◽  
Thyroid Cancer ◽  
Cancer Risk ◽  
Cancer Incidence ◽  
Paranasal Sinuses ◽  
Old Patients ◽  
Thyroid Cancer Risk ◽  
Paranasal Sinuses Ct ◽  
Age Range ◽  
Thyroid Cancer Incidence

Purpose: Computed Tomography (CT) is a fundamental part of diagnosis of diseases. During CT examinations organs in and out of scanned volume are exposed to ionization radiation. The aim of this study was Estimation Thyroid cancer risk in Patients who Underwent 64 Slice brain and paranasal sinuses CT scan. Materials and Methods: with permission from the authors and editor, data related to thyroid dose of 40 patients in Mazyar et al.'s paper was used and by using Biological Effects of Ionizing Radiation (BEIR)VII model thyroid cancer risk was calculated for different ages at exposure in male and female. Results: In both brain and paranasal sinuses CT, ERR values in female patients were twice as many as those in male patients. At age range from 20 to 40 years, ERR was considerably more than at age range 40-60 years since young patients are more radiosensitive than old patients. Conclusion: The calculations of ERR indicate that PNS and brain CT increase the theoretical risk of thyroid cancer incidence. Although the ERR values are low, impacts on the thyroid cancer incidence should not be disregarded.

Increased thyroid cancer risk in acromegaly

2013 ◽  
Author(s):  
Selcuk Dagdelen ◽  
Nese Cinar ◽  
Tomris Erbas
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Cancer Risk

scholarly journals Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
QingAn Yu ◽  
XiaoYing Lv ◽  
KunPeng Liu ◽  
DaKun Ma ◽  
YaoHua Wu ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Clomiphene Citrate ◽  
Positive Association ◽  
Female Infertility ◽  
Cochrane Library ◽  
Significant Positive Association ◽  
Fertility Drugs ◽  
Increased Risk ◽  
Thyroid Cancer Risk

Associations have been demonstrated between fertility drugs and a variety of hormone-sensitive carcinomas. The purpose of this study was to determine the relationship between fertility drugs used in the treatment of female infertility and the risk of thyroid cancer. To investigate the clinical significance of fertility drugs used for the treatment of female infertility and the risk associated with thyroid cancer, we performed a literature search using PubMed, MEDLINE, the Cochrane Library, the Web of Science, and EBSCOHOST for comparative studies published any time prior to July 21, 2017. The studies included women who were treated for infertility with fertility drugs, such as clomiphene citrate, gonadotropins, or other unspecified fertility agents, which reported the incidence of thyroid cancer as the main outcome. Eight studies were included in the meta-analyses. Among women with infertility, there was a significant positive association between thyroid cancer risk and the use of fertility drugs (relative risk [RR] = 1.35; 95% confidence interval [CI] 1.12–1.64; P=0.002). Additionally, among women with infertility, the use of clomiphene citrate was associated with an increased risk of thyroid cancer compared to women who did not use fertility drugs (RR = 1.45; 95% CI 1.12–1.88; P=0.005). After pooling results, we found that the parity status of infertile women using fertility drugs was not associated with thyroid cancer risk (RR = 0.99; 95% CI 0.61–1.58, P=0.95). In summary, clomiphene citrate (the most commonly used fertility drug) and other fertility drugs are associated with an increased risk of thyroid cancer.

Contribution of industrial density and socioeconomic status to the spatial distribution of thyroid cancer risk in Hangzhou, China

2018 ◽  
Vol 613-614 ◽  
pp. 679-686 ◽  
Author(s):  
Xufeng Fei ◽  
Zhaohan Lou ◽  
George Christakos ◽  
Qingmin Liu ◽  
Yanjun Ren ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Spatial Distribution ◽  
Thyroid Cancer ◽  
Cancer Risk ◽  
Thyroid Cancer Risk

scholarly journals A Study of Artificial Sweeteners and Thyroid Cancer Risk

2020 ◽  
Vol 12 (8) ◽  
pp. 492-498
Author(s):  
Navdeep Singh ◽  
Sandeep Singh Lubana ◽  
Saurabh Arora ◽  
Issac Sachmechi
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Artificial Sweeteners ◽  
Thyroid Cancer Risk

scholarly journals An overall and dose-response meta-analysis for thyrotropin and thyroid cancer risk by histological type

Oncotarget ◽  
2016 ◽  
Vol 7 (30) ◽  
pp. 47750-47759 ◽  
Author(s):  
Na Hu ◽  
Zhan-Ming Li ◽  
Jin-Feng Liu ◽  
Zhen-Zhen Zhang ◽  
Li-Shun Wang
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Dose Response ◽  
Meta Analysis ◽  
Histological Type ◽  
Thyroid Cancer Risk

scholarly journals The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case–control study in South Korea

2012 ◽  
Vol 109 (1) ◽  
pp. 118-128 ◽  
Author(s):  
Su Kyoung Jung ◽  
Kirang Kim ◽  
Kyung Tae ◽  
Gu Kong ◽  
Mi Kyung Kim
Keyword(s):  
Thyroid Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Early Stage ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Dietary Factors ◽  
Inverse Association ◽  
Thyroid Cancer Risk ◽  
Control Study

Thyroid cancer is the most common cancer among Korean women. However, there are few data on dietary factors related to thyroid cancer risk. The objective of the present study was to evaluate the association between raw vegetables and fruits intake and thyroid cancer in a case–control study. We included 111 histologically confirmed malignant thyroid cancer cases and 115 benign cases. Controls who did not have nodules in thyroid ultrasonography were matched to cases by age ( ± 2 years). Food and nutrient intakes were estimated using a quantitative FFQ with 121 items. Conditional logistic regression analysis was used to obtain OR and corresponding 95 % CI. The intake of total vegetables was not associated with malignant thyroid cancer, but inversely associated with benign cases. High raw vegetable intake was inversely associated with thyroid cancer risk both in malignant and benign cases (P for trend = 0·01 in both malignant and benign cases). Among fruits, persimmon intake had an inverse association with thyroid cancer risk in both malignant and benign cases (P for trend = 0·06 in malignant cases; P for trend = 0·01 in benign cases) and tangerine intake had an inverse association in malignant cases (P for trend = 0·03). The frequency of consumption of raw vegetables and persimmon also had a consistent inverse association in both malignant and benign cases. These results suggest that high consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer.

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