PROFIL AKNE VULGARIS DI RSUP Prof. Dr. R. D. KANDOU MANADO PERIODE 2009-2011

Abstract: Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles that commonly occurs in adolescence and can heal itself. The purpose of this study was to determine the profile of acne vulgaris in Dermatovenereology of Prof. Dr. R. D. Kandou Manado in 2009-2011. This study was conducted retrospectively in patients with acne vulgaris who came to the Dermatology clinic in 2009-2011. The data were recorded from medical records of the amounts of patients, gender, age, occupation / education, lesion location, and the type of acne. The results showed that of a total of 10003 visits in 2009-2011 there of 121 patients (3.59%) were new cases of acne vulgaris, acne vulgaris in patients dominance of female patients by 75 patients (61.9%), the age group most at 15-24 years old is 76 patients (62.8%), the highest educational status on the student group is 73 patients (60.3%), the most lesions location are on the face, most types of acne is papulopustular. Key words: acne vulgaris, inflammation, pilosebaceous Abstrak: Akne vulgaris adalah penyakit peradangan menahun folikel pilosebasea yang umumnya terjadi pada masa remaja dan dapat sembuh sendiri. Tujuan dari penelitian ini untuk mengetahui profil akne vulgaris di poliklinik Kulit dan Kelamin RSUP Prof Dr R. D. Kandou Manado pada tahun 2009–2011. Penelitian ini dilakukan secara retrospektif pada pasien dengan akne vulgaris yang datang ke poliklinik Kulit dan Kelamin pada tahun 2009–2011. Dilakukan pencatatan data dari catatan medik mengenai jumlah pasien, jenis kelamin, usia, pekerjaan/pendidikan, lokasi lesi, dan jenis akne. Hasil yang diperoleh menunjukkan bahwadari total 10003 kunjungan pada tahun 2009–2011 terdapat 121pasien (3,59%) merupakan penderita baru akne vulgaris, pasien akne vulgaris di dominasi pasien perempuan sebanyak 75 pasien (61,9%), kelompok usia terbanyak pada usia 15 – 24 tahun yaitu 76 pasien (62,8%), status pendidikan terbanyak pada kelompok pelajar yaitu 73 pasien (60,3%), lokasi lesi terbanyak yaitu di bagian wajah, jenis akne terbanyak yaitu papulopustuler. Kata kunci: akne vulgaris, pilosebasea, radang

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Skull and Face Injuries and Associated Factors in Pedestrian Victims of Traffic Accidents: A Single Trauma Center Analysis

Current Dentistry ◽

10.2174/2542579x02999200608131337 ◽

2020 ◽

Vol 2 (1) ◽

pp. 53-59

Author(s):

Josimara A. de Araújo Varela ◽

Tatiana F.T. Palitot ◽

Smyrna L.X. de Souza ◽

Alidianne F.C. Cavalcanti ◽

Alessandro L. Cavalcanti

Keyword(s):

Medical Records ◽

Associated Factors ◽

Traffic Accidents ◽

Age Group ◽

Chi Square ◽

Cross Sectional ◽

Significance Level ◽

The Face ◽

Chi Square Test ◽

The City

Objective: This study aimed to analyze the presence of lesions in the skull and face and the associated factors in pedestrian victims of traffic accidents. Methods: A cross-sectional, descriptive-analytical study carried out through the analysis of medical records of pedestrian victims of traffic accidents in an emergency service in the city of Campina Grande, Brazil, during the year of 2016. Information was collected regarding gender, age group, day of the week, time of the accident, type of vehicle involved, presence of trauma to the skull and face, and outcomes. The Chi-square and Fisher's Exact tests were used, with a significance level of 5%. Results: A total of 1,884 medical records were evaluated, out of which 7.1% (n = 133) involved pedestrians. Men were the most frequent victims (68.4%), and victims of age 60 years old or over (30.5%) predominated. Almost one-third of the cases were recorded during the weekends (30.5%), and the most prevalent time was at night (52.7%). Regarding the type of vehicle involved, motorcycles predominated (47.4%). Head trauma was present in 37.6% of victims, while facial injuries corresponded to 8.2%. In 12% of cases, the victims died. The variables of gender, age group, occurrence on weekends, and trauma to the face showed a statistically significant association with the occurrence of traffic accidents (Chi-square test; p<0.05). Conclusion: Among pedestrian victims of traffic accidents, there is a predominance of men aged 65 years or over. Accidents are frequent at night, and motorcycles are the main vehicles involved. The presence of trauma to the skull and face regions is high.

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PROFIL KANDIDIASIS VULVOVAGINALIS DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. Dr. R. D. KANDOU MANADO PERIODE JANUARI - DESEMBER 2012

e-CliniC ◽

10.35790/ecl.3.3.2015.10155 ◽

2015 ◽

Vol 3 (3) ◽

Author(s):

Aljufri Syamsudin ◽

Marlyn G. Kapantow ◽

Renate T. Kandou

Keyword(s):

Retrospective Study ◽

Medical Records ◽

Clinical Manifestations ◽

Age Group ◽

Dermatology Clinic

Abstract: Candidiasis vulvovaginalis (candida vulvovaginitis) is an infection of the vagina or vulva by Candida genus, with a variety of clinical manifestations that can occur acutely, chronically, or episodically. This study aimed to determine the profile of candidiasis vuvovaginalis in the Dermatology clinic Prof. Dr. R. D. Kandou Manado during the period of January to December 2012. This was a retrospective study using the medical records of new patients with a diagnosis of candidiasis vulvovaginalis. The results showed that there were 30 patients (2.73%) with candidiasis vulvovaginalis among 1096 new patients. It was more commonly found in women with the largest age group 25-44 years, residence in Manado, and as housewives, The most frequent therapy was systemic antifungals and antihistamine. The occurence of this disease was associated with other diseases such as bacterial vaginosis.Keywords: vulvovaginaliscandidosis, candida albicansAbstrak: Kandidiasis vulvovaginalis (kandidosis vulvovaginalis, kandida vulvovaginitis) adalah infeksi vagina dan atau vulva oleh Genus Candida, dengan berbagai manifestasi klinisnya yang bisa berlangsung akut, kronis atau episodik. Penelitian ini bertujuan untuk mengetahui profil kandidiasis vuvovaginalis di poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari – Desember 2012. Penelitian ini dilakukan secara retrospektif dari rekam medik pasien baru dengan diagnosis kandidiasis vulvovaginalis. Hasil penelitian menunjukkan bahwa terdapat 30 pasien (2,73%) kandidiasis vulvovaginalis dari 1.096 pasien baru, lebih banyak ditemukan pada perempuan dengan kelompok umur 25-44 tahun, didapatkan bahwa wilayah tempat tinggal terbanyak adalah Kota Manado, menurut pekerjaan paling banyak terjadi pada IRT (Ibu rumah tangga), terapi yang banyak digunakan adalah Antijamur sistemik+antihistamin, dan kombinasi kandidiasis vulvovaginalis dengan penyakit lain terbanyak yaitu kandidiasis vulvovaginalis + bakterial vaginosis.Kata kunci: kandidiasis vulvovaginalis, candida albican, penelitian retrospektif

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Clinical profile of acne vulgaris in semiurban patients

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20180120 ◽

2018 ◽

Vol 4 (1) ◽

pp. 23

Author(s):

Kshitij Saxena ◽

Yogesh M. Shah ◽

K. K. Singh ◽

Shobhit Dutt ◽

Meenal Agrawal ◽

...

Keyword(s):

Age Of Onset ◽

Acne Vulgaris ◽

Chronic Inflammatory Disease ◽

Clinical Profile ◽

Acne Lesion ◽

Dermatology Clinic ◽

Common Skin ◽

Associated Conditions ◽

Acne Scarring ◽

Grade 3

Background: Acne is a chronic inflammatory disease of the pilosebaceous unit, mainly affecting face and frequently followed by scarring. It is the most common skin disease in an urban dermatology clinic in India. Adult acne is more common in women and may be a marker of hyperandrogenism.The present study was carried out to study the clinical profile of acne vulgaris in semiurban patients.Methods: The study was conducted for 1 year on all eligible patients of acne vulgaris attending dermatology OPD of a hospital catering to semiurban patients. Data including grade of acne, markers of androgenicity and post-acne scarring was collected. Statistical analysis was done using SPSS 15 software.Results: Frequency of acne vulgaris patients in the dermatology OPD was 2.8% with 429 acne patients out of 15,322 new patients. Female to male ratio was 1.44:1. The mean age of onset in males was 16.24 and in females, 14.84 years. Grade 2 acne (66%) was commonest followed by grade 3 (5.1%) and grade 4 (3.7%). Associated conditions seen were seborrhea (60.8%), alopecia (18.9%), acanthosis (4.9%) and PCOD (2.3%). Markers of androgenicity were more frequently seen in grade 2 acne which was statistically significant. Atrophic scars were commonest including icepick scars (80.2%), rolling scars (67.4%) and box scars (57.8%). Conclusions: In our study females had an earlier onset and closed comedones were the most common acne lesion. Grade 2 acne vulgaris formed majority of patients. Grade 4 acne vulgaris was more common in males.

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Hubungan Stress Dan Kebersihan Wajah Terhadap Kejadian Akne Vulgaris Pada Mahasiswa Kedokteran Universitas Malahayati

Malahayati Nursing Journal ◽

10.33024/manuju.v3i1.3398 ◽

2021 ◽

Vol 3 (1) ◽

pp. 11-18

Author(s):

Resati Nando Panonsih ◽

Ratna Purwaningrum ◽

Arief Efendi ◽

Wafiq Desarta

Keyword(s):

Acne Vulgaris ◽

Statistical Test ◽

Hair Follicles ◽

Medical Faculty ◽

P Value ◽

Test Results ◽

Cross Sectional ◽

The Face ◽

Relationship Of ◽

Akne Vulgaris

ABSTRACT: RELATIONSHIP OF STRESS AND FACE CLEANLINESS TO THE EVENT OF VULGARIS IN MEDICAL STUDENTS OF UNIVERSITAS MALAHAYATI Background: Acne vulgaris is a disorder of the sebaceous follicles specifically associated with hair follicles and sebaceous glands are the most common found on the face, chest, and back. Acne vulgaris associated with facial cleanliness and psychological stress. Objective: This research is aiming to know reletionship of stress and hygiene face of acne vulgaris in malahayati university medical faculty student.Methods: This study using cross sectional method. Subjects consisted of 324 respondents using questionnaires and physical examination.Result: Statistical test results are obtained p-value=0,000 which means p<α (Ho rejected and Ha accepted) so it can be concluded that there is a stress relationship to the onse of acne vulgaris. An OR score of 26,414, cause stress with respondents had a 26,414 times greater chance of akne vulgaris than those who did not experience stress. Statistical test results are obtained p-value=0.000 with an OR value of 3,452.Conclusion: There is a relationship of stress and facial hygiene to the incidence of akne vulgaris in students of the university's medical faculty instead. Keywords :Acne vulgaris, stress, facial cleanline INTISARI: HUBUNGAN STRESS DAN KEBERSIHAN WAJAH TERHADAP KEJADIAN AKNE VULGARIS PADA MAHASISWA KEDOKTERAN UNIVERSITAS MALAHAYATI Latar belakang :Akne vulgaris adalah suatu kelainan dari folikel sebasea berupa komedo khusus yang berkaitan dengan folikel rambut dan kelenjar sebasea yang tersering dijumpai pada wajah, dada, dan punggung. Akne vulgaris berhubungan dengan kebersihan wajah dan stres psikologis.Selain stres, kebersihan wajah juga merupakan salah satu faktor timbulnya akne vulgaris.Tujuan :Penelitian ini bertujuan untuk mengetahui hubungan stres dan kebersihan wajah terhadap kerjadian akne vulgaris pada mahasiswa fakultas kedokteran universitas malahayatiMetode :Penelitian ini menggunakan metode crossectional. Subjek penelitian terdiri dari 324 responden dengan menggunakan kusioner dan pemeriksaan fisik pada responden.Hasil : Hasil uji statistik diperoleh p-value=0,000 yang berarti p<α (Ho ditolak dan Ha diterima) maka dapat disimpulkan bahwa ada hubungan stress terhadap terjadinya acne vulgaris.Dengan nilai OR 26,414 berarti responden stress memiliki peluang 26,414 kali lebih besar untuk terjadinya akne vulgaris dibandingkan responden yang tidak mengalami stress.Hasil uji statistik diperoleh p-value=0,000 dengan nilai OR 3,452.Kesimpulan :Adahubungan stres dan kebersihan wajah terhadap kejadian aknevulgaris pada mahasiswa fakultas kedokteran universitas malahayati Kata kunci: akne vulgaris, stres, kebersihan wajah

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PROFIL TUMOR JINAK KULIT DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R. D KANDOU MANADO PERIODE 2009-2011

e-CliniC ◽

10.35790/ecl.1.1.2013.3291 ◽

2013 ◽

Vol 1 (1) ◽

Author(s):

Grace Agustin Gefilem

Keyword(s):

Medical Records ◽

Malignant Tumors ◽

Skin Tumor ◽

Benign Tumors ◽

Tumor Type ◽

Age Group ◽

Seborrheic Keratosis ◽

Men And Women ◽

Verruca Vulgaris ◽

Dermatology Clinic

Abstract: Introduction: Benign skin tumor manifestation of chaos skin growths that are congenital or akuisita, without the invasive and metastatic tendency, can be derived from vascular and non-vascular. Benign tumors was often said to be dangerouly because it is not develop into malignant tumors, howver skin tumor needs to be understood because causing disability (ruin the appearance) and also at an advanced stage can be fatal in body health.Objective: To know the profile of patients benign skin tumor, age, gender and employment in the Dermatology Clinic Dr Prof Dr. R. D. Kandou Manado for 3 years (January 2009 - December 2011). Subjects and Methods: A retrospective study of benign skin tumor of the medical records of new patients based on tumor type, age, sex, and occupation.Results: There were 478 (15.65%) patients of benign skin tumor among 3055 new patients. Verruca vulgaris (28.03%) and seborrheic keratosis (24.69%) most frequently encountered. Highest age group is 15-44 years is 49.16%. The ratio of men and women for benign skin tumor is 1:1,12. Most jobs are housewives (26.36%). Conclusion: verruca vulgaris is the most benign skin tumor. Benign skin tumor was more common in women. Highest age group is 15-44 years. Most jobs are housewives.Keywords: skin tumors, benignAbstrakPendahuluan: Tumor jinak kulit merupakan manifestasi dari kekacauan pertumbuhan kulit yang bersifat kongenital atau akuisita, tanpa tendensi invasif dan metastasis, dapat berasal dari vaskuler dan non vaskuler. Tumor jinak sering dikatakan tidak berbahaya karena tidak sampai berkembang menjadi keganasan namun demikian, tumor kulit perlu dipahami karena selain menyebabkan kecacatan (merusak penampilan) juga pada stadium lanjut dapat berakibat fatal kesehatan tubuh.Tujuan: Mengetahui profil pasien tumor jinak kulit berdasarkan jenis tumor, umur, jenis kelamin dan pekerjaan di Poliklinik Kulit dan Kelamin RSUP Prof Dr. R. D. Kandou Manado selama 3 tahun (Januari 2009- Desember 2011).Subyek dan Metode: Penelitian retrospektif tumor jinak kulit terhadap catatan medis kasus baru berdasarkan jenis tumor, usia, jenis kelamin, dan pekerjaan.Hasil: Terdapat 478 (15,65 %) pasien tumor jinak kulit di antara 3055 pasien baru. Veruka vulgaris (28,03%) dan keratosis seboroik (24,69%) paling sering dijumpai. Kelompok usia terbanyak adalah 15–44 tahun sejumlah 49,16%. Rasio laki-laki dan perempuan untuk tumor jinak kulit ialah 1:1,12. Pekerjaan terbanyak ialah ibu rumah tangga (26,36%).Kesimpulan: Veruka vulgaris merupakan tumor kulit jinak terbanyak. Tumor kulit jinak lebih sering terjadi pada perempuan. Kelompok usia tertinggi adalah 15–44 tahun. Pekerjaan terbanyak adalah ibu rumah tangga.Kata kunci: tumor kulit, jinak

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MEDICINAL LEECH FOR THE TREATMENT OF ACNE VULGARIS W.S.R. TO MUKHADUSHIKA: A RANDOMISED CLINICAL STUDY

AYUSHDHARA ◽

10.47070/ayushdhara.v8i1.685 ◽

2021 ◽

pp. 3064-3070

Author(s):

Gupta Sudesh ◽

Sharma Sakshi ◽

Prasher Aarushi ◽

Sharma Kumar Arun ◽

Manhas Raman

Keyword(s):

Acne Vulgaris ◽

Signs And Symptoms ◽

Medicinal Leech ◽

Inflammatory Disorder ◽

Age Group ◽

Time Saving ◽

Chronic Inflammatory Disorder ◽

Effective Time ◽

The Face

Acne vulgaris is a chronic inflammatory disorder of the pilo-sebaceous follicles characterised by comedones, papules, pustules, nodules and often scars mainly seen on cheeks, chin, nose, forehead and upper trunk during adolescence. The symptoms of Acne vulgaris resemble Mukhadushika as per Ayurvedic classics. Acharya Sushruta has mentioned Mukhadushika as one of the Kshudra Rogas. In Mukhadushika, there are Shalmali kantak like eruptions on the face which are impregnated with Meda caused due to vitiation of Kaphadosha, Vatadosha and Raktadhatu which destroy the beauty of the face and makes the appearance ugly. The disease almost take place in adolescent and young age group prominently therefore is also known as Yuvanapidika. Acharya Sushruta stated Jalaukavacharana is the preferred method of bloodletting in Sukumara. Aim: To evaluate the efficacy of Jalaukavacharana in the management of Acne vulgaris w.s.r. to Mukhadushika. Methodology: Fourteen patients of age group 15-30 years having signs and symptoms of Mukhadushika were selected and four sittings of Jalaukavacharana on a seven day interval were given. Apart from treatment duration of 28 days, a follow-up was also done after 30 days. Results: Intervention was found to be highly significant (p<0.001) in Vedana, Kandu, Daha, number of Pidika, size of Pidika, Pidika ghanata, Shotha, Vaivarnyata. However, significant effect (p<0.05) was found in Vranavastu and non-significant result (p>0.05) was found in Srava. Conclusion: The results are satisfactory. Jalaukavacharana is proved to be an effective, time saving, affordable and acceptable treatment in Mukhadushika without causing any adverse effect.

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The role of dviharidradi taila locally in the managment of mukhadushika w.s.r. to acne vulgaris –A case study.

Ayurline: International Journal of Research in Indian Medicine ◽

10.52482/ayurline.v5i03.552 ◽

2021 ◽

Vol 5 (03) ◽

Author(s):

Sneha Z. Borutkar

Keyword(s):

Acne Vulgaris ◽

Female Gender ◽

Underlying Mechanism ◽

Self Esteem ◽

Age Group ◽

Oil Glands ◽

Common Chronic Disease ◽

The Face

Acne vulgaris is a common chronic disease involving blockage and /or inflammation of pilosebaceous units. Acne can presents as noninflammatory lesions, inflammatory lesions, or a mixture of both, affecting mostly the face but also the back and chest. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and possible scarring. It primarily affects skin with a relatively high number of oil glands, including the face, upper part of the chest, and back. The resulting appearance can lead to anxiety, reduced self-esteem, and in extreme cases depression. It is the commonest dilemma associated with complexion and smoothness of skin .sometimes leading to major skin problems, which is characterized by macula, papulo, pustular eruption on the skin, especially on the face. Both male and female gender of adolescent age group are commonly affected. Genetics is the primary cause of acne in 80%of cases. The role of diet and cigarette smoking in the condition is unclear and neither cleanliness nor exposure to sunlight appears to play a part. In both sexes, hormones called androgens appear to be part of the underlying mechanism, by causing increased production of sebum. In the Ayurvedic perspective Acne Vulgaris can be correlated with Mukhadushika . Mukhadushika is explained by Aacharya Sushruta under kshudra rogas and is considered as swatantra vyadhi in the ayurvedic literature. It is characterized by shalmali kantaka sadrusha pidika on the face. Mukhadushika is also called as Tarunya pitika.

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Hubungan Indeks Massa Tubuh dan Angka Kejadian Akne Vulgaris pada Siswa-siswi di SMA Frater Don Bosco Manado

e-CliniC ◽

10.35790/ecl.5.2.2017.18457 ◽

2017 ◽

Vol 5 (2) ◽

Author(s):

Ni M.S. Kristiani ◽

Marlyn G. Kapantouw ◽

Thigita A. Pandaleke

Keyword(s):

Body Mass Index ◽

Growth Factor ◽

Body Mass ◽

Acne Vulgaris ◽

Chronic Inflammatory Disease ◽

Insulin Like Growth Factor ◽

Hormone Production ◽

Cross Sectional ◽

Cross Sectional Design ◽

Akne Vulgaris

Abstract: Acne vulgaris is a chronic inflammatory disease of the pilosebasea follicle. Although the cause of acne vulgaris is not known for certain but there are several pathogenesis suspected to have some effects on the occurrence of acne vulgaris, inter alia the increase in sebum production which is controlled by androgen hormones. Stimulation of androgen hormone production is associated with elevated level of insulin-like growth factor-1 (IGF-1). Increased IGF-1 is correlated positively with body mass index (BMI). In general, acne vulgaris begins at age 12-15 years and most occur in adolescents aged 15-18 years. This study was aimed to determine the relationship between BMI and the incidence rate of acne vulgaris in students at SMA Frater Don Bosco Manado (senior high school). This was an analytical survey observation with a cross sectional design. Subjects were 69 students obtained by using systematic random sampling. Of the 69 students suffered from acne vulgaris, there were 8 (11.6%) with thin BMI; 50 (72.5%) with normal BMI; and 11 (15.9%) with fat and obese BMI. Conclusion: There was no significant association between BMI and the incidence of acne vulgaris among the students at SMA Frater Don Bosco Manado.Keywords: body mass index, acne vulgaris Abstrak: Akne vulgaris adalah penyakit radang kronis pada folikel pilosebasea. Walaupun penyebab dari akne vulgaris belum diketahui pasti namun terdapat beberapa patogenesis yang diduga berpengaruh pada timbulnya akne vulgaris, salah satunya yaitu peningkatan produksi sebum di bawah kontrol hormon androgen. Stimulasi produksi hormon androgen berhubungan dengan peningkatan kadar insulin-like growth factor-1 (IGF-1). Peningkatan IGF-1 berkorelasi positif dengan indeks massa tubuh (IMT). Umumnya akne vulgaris dimulai pada usia 12-15 tahun dan terbanyak pada remaja usia 15-18 tahun. Penelitian ini bertujuan untuk mengetahui hubungan antara IMT dan angka kejadian akne vulgaris pada siswa-siswi di SMA Frater Don Bosco Manado. Jenis penelitian ialah observasi analitik survei dengan desain potong lintang. Subyek penelitian ialah siswa-siswi di SMA Frater Don Bosco Manado diperoleh dengan pengambilan sampel secara acak sistematis. Pada 69 subyek dengan akne vulgaris, terdapat 8 orang (11,6%) dengan IMT kurus; 50 orang (72,5%) dengan IMT normal; dan 11 orang (15,9%) dengan IMT gemuk dan obesitas. Simpulan: Tidak terdapat hubungan bermakna antara IMT dan angka kejadian akne vulgaris pada siswa-siswi di SMA Frater Don Bosco Manado.Kata kunci: indeks massa tubuh, akne vulgaris

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Knowledge, attitude and practice towards acne vulgaris among acne patients

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20170797 ◽

2017 ◽

Vol 3 (1) ◽

pp. 107

Author(s):

Manjunath Hulmani ◽

Asha Bullappa ◽

Shruti Kakar ◽

Prakash Kengnal

Keyword(s):

Acne Vulgaris ◽

Chronic Inflammatory Disease ◽

Good Knowledge ◽

Age Group ◽

Cross Sectional ◽

Medical College ◽

Spicy Food ◽

Attitude And Practice ◽

Unfavorable Attitude ◽

Knowledge Attitude And Practice

Background: Acne is a chronic inflammatory disease known to occur in adolescent age group. There are many myths and misconceptions in patients as well as health physicians regarding the causes and treatment of acne. Objective of the study was to assess the knowledge, attitude and practice towards acne vulgaris among acne patients attending skin outpatient department in a private medical college.Methods: This is a cross sectional, questionnaire based study conducted between January - April 2016. 100 patients having acne lesions were included in the study.Results: Majority of the study subjects belonged to the age group 15-24. The study showed that 72% had good knowledge. More than half of the study subjects had wrong belief that eating oily foods, chocolates, spicy food caused acne but more than 40% of the study subjects had good knowledge about the causes and aggravating factors like it worsens by squeezing/picking/rubbing (83%), commonly found in oily skin (67%), has seasonal occurrence (54%), associated with premenstrual flare (42%), aggravated with use of cosmetics (41%). Conclusions: The acne patients had poor practice and unfavorable attitude in spite of good knowledge. Many myths exist among patients. Despite being so common and very well responsive to treatment, it is a major cause of depression among patients.

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Evaluation of Serum Interleukin 36 in Egyptian Acne Vulgaris Patients versus Controls

QJM ◽

10.1093/qjmed/hcab093.015 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Maha Mohamed Adel Shahin ◽

Marwa Yassin Ahmed Soltan ◽

Esraa Mahmoud Awaad

Keyword(s):

Acne Vulgaris ◽

Serum Levels ◽

Chronic Inflammatory Disease ◽

University Hospitals ◽

Innate And Adaptive Immunity ◽

Dermatology Clinic ◽

Probable Role ◽

Sebum Production ◽

High Degree ◽

Control Study

Abstract Background Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, and it is one of the most common dermatological conditions worldwide. Some of the key mechanisms of pathogenesis are the disturbed sebaceous gland activity associated with excess sebum production and alterations in sebum fatty acid composition, dysregulation of the hormone microenvironment, interaction with neuropeptides, follicular hyperkeratinization, and induction of inflammation and dysfunction of the innate and adaptive immunity. Objectives We aimed to evaluate the serum IL36 levels in acne vulgaris patients in comparison with healthy controls and to correlate its level to different severities of acne vulgaris. Patients and Methods This is a case control study which included 30 acne vulgaris patients who were recruited from the Outpatient Dermatology Clinic at Ain Shams University Hospitals during the period between September 2018 and December 2018. Results The study revealed a highly significant increase in IL-36 serum levels which can differentiate cases form controls with a high degree of specificity of the test according to the ROC curve However, there was no association between IL-36 and the disease severity. Expression of high levels of IL-36 in all acne cases including mild cases suggests a probable role in early inflammatory stage of the disease. Furthermore, duration of the disease, body mass index, family history and sex were all insignificant factors on affecting IL-36 levels. Conclusion We found that IL-36 is involved in acne pathogenesis and its serum levels are elevated even in mild cases with comedonal lesions suggesting the possible involvement in the early events of acne vulgaris. Further studies are required to demonstrate more detailed explanation of IL-36 pathogenic role in acne.

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