scholarly journals The Improvement of Live Plaque Vaccine Production Technology

2017 ◽  
Vol 1 (3) ◽  
pp. 30-37
Keyword(s):  
Production Technology ◽  
Technical Information ◽  
Submerged Cultivation ◽  
Central Scientific Research Institute ◽  
Federal Target Program ◽  
Hardware System ◽  
Automated Information System ◽  
The Russian Federation ◽  
Branch Office ◽  
Central Scientific

The article is dedicated to the possible improvement of the production technology of live plaque vaccines. The automated information system (AIS) of the control of the production of pharmaceuticals has been elaborated in the branch office of the «48 Central Scientific Research Institute» of the Ministry of Defence of Russia (Kirov) within the framework of the federal target program «The National System of Chemical and Biological Security of the Russian Federation». The AIS has been used for the improvement of the technology of submerged cultivation of live plaque vaccine. Strain EV, line NIIEG, as well as the upgraded fermenter BIOR-0,25 with the AIS of the control of the production have been used in this work. The problems of the improvement of the production technology of pharmaceuticals have been studied. The possibility of shared use of the fermenters and AIS of the control of the production of pharmaceuticals has been proven experimentally. This hardware system can accumulate, systemize and record scientific and technical information about all the operations. The above-mentioned studies allow to enhance the technological capabilities of the equipment and to improve the stage of the submerged cultivation in the production of live plaque vaccine.

scholarly journals Membrane Technology in the Production of Immunobiological Preparations Produced by the Branch Office of the FSBE «48 Central Scientific Research Institute» of the Ministry of Defence of Russia (Kirov)

2019 ◽  
Vol 3 (2) ◽  
pp. 137-149
Author(s):  
Leshchenko A.A. , Krupin V.V
Keyword(s):  
Scientific Research ◽  
Scientific Research Institute ◽  
Centrifugal Separation ◽  
Central Scientific Research Institute ◽  
Filtration Method ◽  
Microbial Cells ◽  
Vaccinal Strain ◽  
Branch Office ◽  
Central Scientific ◽  
Research Institute

The researchers of the Branch Office of the Federal State Budgetary Establishment «48 Central Scientific Research Institute» of the Ministry of Defence of the Russian Federation (Kirov) organized theoretical and experimental studies on the introduction of a tangential filtration method for the separation of biological mixtures into the production of immunobiological preparations. The method of microfiltration in the tangential stream replaced the process of sedimentation at the stage of concoction of intermediate vaccines, reduced considerably the process time, and allowed to obtain suspensions from cultural liquid, substandard on an indicator of concentration of microbial cells. Along with this, the microfiltration method allowed to concentrate the cultures of Yersinia pestis of a vaccinal strain EV. In comparison with the centrifugal separation, the concentration of living microbial cells of a vaccinal strain of EV Y. pestis increased by one and a half times. The filtration in a tangential stream at the ASF-020 installation from the point of view of the production of the sporous product of anthrax vaccine STI-1 (in millions of doses), is 1.8 times more effective in comparison with the centrifugal separation. The membrane method allowed to reduce the duration of technological process. These membrane processes are used nowadays during the production of plague and anthrax vaccines, anthrax immunoglobulin, diagnostic medicines and during the sterilization of liquid nutrient mediums. This type of equipment for the sterilization of nutrient mediums can be considered as an alternative to the processes of the thermal sterilization of liquids and provides their biological and technological full functionality. Experiments on the use of the ceramic-metal filters sterilizing the air given for aeration, showed the decrease in duration of preparatory operations on 20 h and increase in the general operational opportunities of the system.

ISSUES OF CONTINUITY OF APPROACHES TO URBAN IMPROVEMENT AND GREENING

2021 ◽  
pp. 5-13
Author(s):  
S.B. Chistyakova ◽  
Keyword(s):  
Urban Planning ◽  
Scientific Research ◽  
Subject Area ◽  
Scientific Research Institute ◽  
Central Scientific Research Institute ◽  
Historical Buildings ◽  
Domestic Science ◽  
Natural Landscapes ◽  
Central Scientific ◽  
Research Institute

The article has been prepared on the basis of many years of research at the Central Scientific Research Institute of Urban Development in the 1970s and 1990s and later works, including those carried out at the Central Scientific Research Institute of Construction of the Ministry of Construction of Russia. The ecological prerequisites of urban planning and the principle of the formation of the natural-ecological frame of the territories of cities as a planning basis for their improvement and landscaping are considered. Taken into account studies of 2019-2020. Since the beginning of the new century, the professional environment has been discussing the negative trends of modern urban planning and urban improvement, accompanied by the loss of their individual appearance. This takes place in the conditions of a market economy and world processes of globalization, which in our subject area are usually called "urbanism". This situation is typical for most cities, and not only for megalopolises, but also for small historical cities. It is shown that excessive unification and depersonalization of the urban environment can be overcome by relying on the fundamental achievements of domestic science and practice. It is also necessary to use systemic, socially oriented and environmentally oriented approaches to the planning and improvement of cities with the formation of interconnected systems of natural and green areas. They should include historical buildings, architectural ensembles and architectural monuments, valuable natural landscapes, historical gardens and parks.

The Mobile Complex of Chemical Control as the Basis of Technical Equipment of the Mobile Diagnostic Group of the 33 Central Scientific Research Test Institute of the Ministry of Defenсe of the Russian Federation

2021 ◽  
Vol 5 (1) ◽  
pp. 54-64
Keyword(s):  
Chemical Control ◽  
Diagnostic Group ◽  
Toxic Chemicals ◽  
Technical Equipment ◽  
Environmental Objects ◽  
The Russian Federation ◽  
The Moment ◽  
Mobile Complex ◽  
Mass Events ◽  
Central Scientific

The special mobile diagnostic group (MDG) is formed in the Federal State Budgetary Establishment «33 Central Scientific Research Test Institute» of the Ministry of Defenсe of the Russian Federation (hereinafter referred to as the institute) to perform tasks related to the radiation and chemical (RCh) control of different objects, to ensure RCh safety and security of mass events, as well as to perform special tasks of RCh examination of samples of all kinds. The purpose of the work is to consider the design, capabilities and organization of the mobile complex of chemical control (MCCC), which is the basis of the technical equipment of the MDG. The complex is created on the basis of Ford-Transit off-road vehicle with the equipment for the MDG and a container installed on a two-axle platform, where the equipment for the MDG is located. The complex is equipped with modern analytical equipment, means of communications, navigation, information processing and automatic meteorological observation, with the life support kit, autonomous power and water supply systems, exhaust ventilation, heating and air conditioning systems. The technical characteristics of the MCCC are as follows: crew – 8 people; preparation time – no more than 60 minutes; time for the preliminary identification of substances detected by the mobile group (from the moment of arrival) – no more than 60 minutes; the lower limit of detection of toxic chemicals in environmental objects – at the maximum concentration limit; time of confirming identification of detected toxic chemicals (from the moment of delivery of samples) – no more than 180 minutes; cruising range – up to 700 km. The methodological apparatus is also developed, that ensures the functioning of the MCCC crew during the performance of wide range of tasks of the MDG. Subsequently, this methodological apparatus has been repeatedly expanded and refined based on the results of the complex's participation in ensuring the RCh security of various mass events. The algorithm of carrying out special chemical control by technical means of the MCCC complex is presented in the article. The complex is capable of detecting both low-hazard and emergency concentrations of practically all known toxic chemicals in various samples, and identifying these substances in environmental objects.

scholarly journals Treasury Control of Budget Expenditures of the Russian Federation Constituent Entities: Practice and Optimization Opportunities.

2021 ◽  
Vol 27 (8) ◽  
pp. 1894-1910
Author(s):  
Marzhinat I. KANKULOVA ◽  
Sabina Z. OSMANOVA
Keyword(s):  
Russian Federation ◽  
Business Processes ◽  
Practical Interest ◽  
Budget Process ◽  
Labor Costs ◽  
Analysis And Synthesis ◽  
Automated Information System ◽  
General Scientific ◽  
The Subject ◽  
The Russian Federation

Subject. This article examines the business processes of treasury control in the course of authorizing budget expenditures of the subject of the Russian Federation. Objectives. The article aims to develop recommendations for improving the business processes of treasury execution of budget expenditures of the subject of the Russian Federation. Methods. For the study, we used the methods of formalization, analysis and synthesis, induction and deduction, comparison, observation, and other general scientific theoretical and empirical research methods. Results. The article identifies reserves for increasing the potential of treasury control of the financial body of the Russian Federation subject by modifying the functionality of the budget process automated information system. It offers recommendations to increase the number of transactions for which extensive documentary control is carried out, while reducing the labor costs for performing the same type of current operations. Conclusions and Relevance. The proposals to optimize treasury control are in line with the solution of common tasks for the development of modern technologies for budget execution based on digitalization and automation of budget procedures. The results obtained may be of practical interest to the financial authorities of the Russian Federation constituent entities (municipalities) that implement their budgets independently through the current budget account opened at the Federal Treasury.

scholarly journals Implementation of the electronic model of the thematic and typological acquisition plan in the scientific library

2021 ◽  
pp. 38-43
Author(s):  
A. S. Pavlova
Keyword(s):  
Technical Information ◽  
Russian Science ◽  
Subsequent Work ◽  
Russian Academy Of Sciences ◽  
Computer Technologies ◽  
Electronic Catalog ◽  
Electronic Model ◽  
Russian Science Citation Index ◽  
Academy Of Sciences ◽  
Central Scientific

Automation of library processes is an important topic in modern conditions of digitalization and transition of human activities to the latest computer technologies. Acquisition of literature to library collections forms the document base for the subsequent work of the library, so this process needs continuous improvement and optimization of its constituent operations. The article is devoted to the application of computer technologies in the preparation and use of the scientific library thematic-typological plan of acquisition as the scientific base of building collections. The object of the article is to present the experience of creating and using the electronic model of the Thematic and Typological Acquisition Plan in the scientific library, to define the perspectives of implementing the data base for information and library servicing UB RAS users.The article presents the results of content analysis of subject headings and indices of the State Rubricator of Scientific and Technical Information for bibliographic descriptions of Russian journals received in 2015–2017, in the Consolidated electronic catalog of periodicals of the Central Scientific Library of the Ural Branch of the Russian Academy of Sciences; of books, published by the institutes of the Ural Branch of the Russian Academy of Sciences in 2015–2017, according to the Electronic catalog of Russian books and continuing publications of the Central Scientific Library of the Ural Branch of the Russian Academy of Sciences; of publications (published in 2015–2019) of the institutes of the Ural Branch of the Russian Academy of Sciences, included in the database of the Russian Science Citation Index on the portal «eLIBRARY.ru» – are presented in the article. It also describes the stages of creation, analyzes the characteristics and capabilities of the database «Thematic-typological acquisition plan» of the Central Scientific Library of the Urals Branch of the Russian Academy of Sciences.

scholarly journals The Eurasian concept of “a multi-national nation” and its value for the development of the Russian state

2020 ◽  
pp. 18-30
Author(s):  
Yu. I. Skuratov
Keyword(s):  
Federal State ◽  
Northern Eurasia ◽  
Federal Target Program ◽  
Theoretical Substantiation ◽  
Russian State ◽  
Target Program ◽  
The Russian Federation ◽  
The Government ◽  
Core Idea ◽  
Foreign Science

INTRODUCTION. This article discusses that part of the classical Eurasian concept, which is devoted to ethno-national relations prevailing in Northern Eurasia, the characteristics of the factors and traditions that determined the formation of the Russian superethnos. The content of the categories “Eurasian nationalism” is revealed, which, according to the classics of the doctrine, should become the core idea of the formation of the Russian multi-national nation. Considerable attention in the article is paid to the analysis of the correlation and interconnection of the categories “people” and “nation”, the characteristics of their specific features.MATERIALS AND METHODS. The article is based on a study of the concepts of Eurasianism presented in domestic and foreign science and the provisions of the Federal Target Program approved by the Government of the Russian Federation “Strengthening the Unity of the Russian Nation and Ethnocultural Development of the Peoples of Russia (2014 – 2020)” are considered.RESEARCH RESULTS. In the article the thesis is substantiated that the modern theoretical substantiation of the tendency for the formation of the “Russian nation” is associated with the desire to strengthen the national substrate of Russia as a single federal state and to avoid the sad experience of the split of the USSR. The author analyzes various approaches to realizing the task of forming a multi-national nation on the basis of the Russian people and shows his own position with respect to the idea of adopting a special Law on the Russian nation.DISCUSSION AND CONCLUSIONS. The article critically evaluates the position that rigidly links the formation of a nation with the creation of its own sovereign national state which in most cases is not applicable to multinational states. 

Problems of environmental management in the Arctic: analysis and solution.

2018 ◽  
Author(s):  
Юрий Кочемасов ◽  
Yuriy Kochemasov ◽  
Екатерина Кочемасова ◽  
Ekaterina Kochemasova ◽  
Наталья Седова ◽  
...  
Keyword(s):  
Environmental Management ◽  
National Security ◽  
Russian Federation ◽  
Action Plan ◽  
The Arctic ◽  
Arctic Zone ◽  
Federal Target Program ◽  
Strategy Of Development ◽  
Target Program ◽  
The Russian Federation

The presented analytical review considers environmental and socio-economic problems of environmental management in the Arctic, the comprehensive studies of which were carried out within the framework of the subprogramme "Development and use of the Arctic" of the Federal target program "World ocean", the Federal target program "risk Reduction and mitigation of natural and man – made emergencies in the Russian Federation", the UNEP/GEF project "Russian Federation-support to The national action plan for the protection of the Arctic marine environment" and other international projects. Many of the author's conceptual and methodological developments remain relevant at present to solve the problems identified in the strategy of development of the Arctic zone of the Russian Federation and national security for the period up to 2020, the Strategy of development of Maritime activities of the Russian Federation until 2030, the Strategy of national security of the Russian Federation. Strategic planning documents have been developed: including the Basics of the state policy of the Russian Federation in the Arctic, the action Plan of the Arctic Council for sustainable development, the Strategic action program (SPD) for environmental protection of the Arctic zone of the Russian Federation, the draft concept of sustainable development of the Arctic zone of the Russian Federation, investment proposals and guidelines for cleaning the Arctic territories from pollution, including in the areas of the Russian presence on the Svalbard archipelago, reduction of natural and man-made risks of emergency situations and increase of protection of valuable natural areas. Also in the monograph are considered: proposals for the regulatory consolidation of the boundaries of the Arctic natural territory in the Russian Arctic to establish a special regime of natural resources, taking into account the high vulnerability of Arctic ecosystems to man-made impacts; methods of causal analysis to determine the relationship between the quality of the environment, the activities of sectors (industries) and the policy of public administration and regulation; road map for the transition from sectoral to complex (integrated) management of marine environmental management; methods of marine spatial planning; strategic environmental assessment of infrastructure projects, etc.

scholarly journals On Assessment of the Results of Implementation of the Water Strategy of the Russian Federation for the Period up to 2020.

2016 ◽  
pp. 4
Author(s):  
Keyword(s):  
Russian Federation ◽  
Program Implementation ◽  
Main Tool ◽  
Strategy Implementation ◽  
Federal Target Program ◽  
Sector Condition ◽  
Target Program ◽  
Calculation Methodology ◽  
The Russian Federation ◽  
Water Strategy

Tools for implementation of the Water Strategy of the Russian Federation for the period up to 2020, its objectives and the degree of its realization have been discussed; effectiveness of the various level executive bodies’ activities on the program implementation has been assessed. Main problems appearing in the process of attaining strategic tasks and objectives have been revealed. The system of target indicators and their calculation methodology have been considered. Outcomes of the independent monitoring of the strategy some objectives realization have been given.Three levels of the target programs (Federal, basin and regional) have been considered as the main tool of the Water Strategy implementation. The Federal target program “Development of the water/economic complex of the Russian Federation in 2012-2020” plays the role. A brief analysis of the Water Strategy and the Federa l Program target indicators has been done; their implementations, problems of their attaining and specific features of their setting have been discussed. Beside analysis of the degree of attaining of the official objectives, an attempt was made to assess some parameters of the water sector condition that indirectly characterized their effectiveness and formed the independent monitoring system. Regional aspects of the expected results have been analyzed in order to understand more clearly the focus points of the Water Strategy implementation; the results of the analysis have been illustrated with thematic maps. The article deals as well with the prerequisites of reviewing the Water Strategy main provisions for the coming period of 2030–2035.

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