scholarly journals CORRELATION BETWEEN ENDOSCOPIC AND HISTOPATHOLOGICAL FINDINGS IN GASTRIC LESIONS.

2019 ◽  
pp. 1-3
Author(s):  
Amarnath Kumar Nayak
Keyword(s):  
Intestinal Metaplasia ◽  
Histopathological Examination ◽  
Medical Science ◽  
Pathological Process ◽  
Endoscopic Examination ◽  
Poor Correlation ◽  
Gastric Lesions ◽  
Female Ratio ◽  
Endoscopic Biopsies ◽  
Male Female Ratio

Background: Stomach is a common site for wide variety of lesions. The visualisation of the site with endoscopy and its biopsy leads to the early detection of the pathological process and appropriate therapy. Objectives: The objective of this study is to correlate the histopathological pattern of endoscopic biopsies with distribution of gastric lesions according to age and sex. Method: The study was carried out among 100 cases with endoscopic biopsies and histological assessment, received at Department of pathology, Rajendra Institute of Medical Science, Ranchi. Result: Out of 100 cases majority of cases were male gender with male : female ratio was 2.1:1. Our study showed a poor correlation between endoscopic and histopathologic evidence of inammation of the stomach. Five cases were diagnosed as intestinal metaplasia which were diagnosed as intestinal metaplasia which were diagnosed endoscopically as ulcer and erosion. Out of 34 of cases diagnosed endoscopically as ulcer , only 4 cases were conrmed histologically. Our study showed good correlation in the cases of carcinoma. Out of 32 cases diagnosed endoscopically as gastric carcinoma correlated histologically as gastric adenocarcinoma. Majority of carcinoma cases showed ulcerating fungating growth followed by ulcero-proliferative growth. Conclusion: Endoscopy is incomplete without biopsy and histopathology. Histopathology is the gold standard for the diagnosis of endoscopically detected lesions. Endoscopic examination and histopathological examination of suspected gastric lesions should go parallel and neither should be a substitute of each other.

scholarly journals Correlation between Endoscopic and Histopathological Findings in Gastric Lesions

2017 ◽  
Vol 13 (3) ◽  
pp. 216-219 ◽  
Author(s):  
S. Sharma ◽  
R. Makaju ◽  
R. Dhakal ◽  
B. Purbey ◽  
R.B. Gurung ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Endoscopic Examination ◽  
Male Gender ◽  
Poor Correlation ◽  
Gastric Lesions ◽  
Common Site ◽  
Female Ratio ◽  
Endoscopic Biopsies ◽  
Male Female Ratio ◽  
Histopathological Evidence

Background Stomach is a common site for wide variety of lesions. The visualisation of the site with biopsy leads to the early detection of the pathologic process and appropriate therapy.Objectives The objective of this study is to correlate the histopathological pattern of endoscopic biopsies with distribution of gastric lesions according to age and sex.Method The retrospective study was carried out among 50 cases with endoscopic biopsies and histopathological assessment, received at Department of Pathology, Dhulikhel Hospital- Kathmandu University Hospital.Result Out of 50 cases majority of cases were of male gender with male: female ratio was 1.3:1. Our study showed a poor correlation between endoscopic and histopathological evidence of inflammation in the stomach. Two cases were diagnosed as intestinal metaplasia which were diagnosed as ulcer and erosion endoscopically. Out of 32% of cases diagnosed endoscopically as ulcer, only one case was confirmed histopathologically. Our study showed good correlation in the cases of carcinoma. Out of 17 cases diagnosed endoscopically as gastric carcinoma correlated histopathologically as gastric adenocarcinoma. Majority of carcinoma cases showed ulcerating fungating growth followed by ulcero-proliferative growth.Conclusion Endoscopy is incomplete without biopsy and histopathology is the gold standard for the diagnosis of endoscopically detected lesions. Endoscopic examination and histopathological examination of suspected gastric lesions should go parallel and neither should be a substitute of each other.

scholarly journals Study of glottic lesions in patients undergoing microlaryngeal surgery

2020 ◽  
Vol 6 (2) ◽  
pp. 277
Author(s):  
Vikrant Mittal ◽  
Manish Munjal ◽  
Rohit Verma ◽  
Parth Chopra ◽  
Hemant Chopra
Keyword(s):  
Clinical Diagnosis ◽  
Histopathological Examination ◽  
Detailed Examination ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Histopathological Correlation ◽  
Male Female Ratio ◽  
Male Preponderance ◽  
Vocal Nodules ◽  
Microlaryngeal Surgery

<p class="abstract"><strong>Background:</strong> Vocal cords are the most common site of laryngeal pathologies. Hoarseness is the sentinel symptom for lesions affecting the glottis. The aim of this study was to categorize various types of lesions affecting the glottis in patients undergoing microlaryngeal surgery. Patients’ demographic profile, gender, occupational factors were studied. Clinical, microlaryngeal and histopathological correlation of the lesions was done.</p><p class="abstract"><strong>Methods:</strong> 50 patients with glottic pathologies undergoing microlaryngeal surgery were included. Patients underwent detailed examination including indirect laryngoscopy, flexible fibreoptic laryngoscopy, followed by microscopic laryngeal examination under general anaesthesia. The lesions were excised using standard microlaryngeal instruments and the specimens were subjected to histopathological examination. The data was analysed.  </p><p class="abstract"><strong>Results:</strong> There was male preponderance (male: female ratio of 1.27:1). Housewives formed the largest group (28%). Commonest pathologies were vocal nodules (34%), vocal polyps (22%) and carcinoma (22%). Microlaryngoscopy was found to be the best means of visualizing the lesions and reaching a clinical diagnosis. In 10 (20%) patients, the final histopathological diagnosis was different from clinical diagnosis.</p><p class="abstract"><strong>Conclusions:</strong> In this study, vocal nodules were the commonest lesions to affect the glottis. Microlaryngoscopy proved to be the best method for examination. Also, there was discrepancy in the clinical and histopathological diagnosis in 20% cases.</p>

scholarly journals Epidemiological Profile of the Head- Neck Pathologies in a Peripheral Referral Institute

2019 ◽  
Vol 27 (2) ◽  
pp. 113-120
Author(s):  
Sabyasachi Ghosh ◽  
Tarak Nath Saha ◽  
Indranil Sen
Keyword(s):  
Head And Neck ◽  
Histopathological Examination ◽  
Neck Region ◽  
Head And Neck Cancers ◽  
Base Line ◽  
Age Group ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Epidemiological Profile ◽  
Head Neck

Introduction   Head and neck lesions encompass a multitude of disorders which can be broadly classified into two groups: Benign and Malignant. Overall 57.5% of global head and neck cancers comes from Asia itself and India alone constitutes 30% of it. Therefore, it is of prime essence that need based and coordinated research for understanding the threats to the nation from chronic diseases such as head and neck cancers and ways to defy such threats should gain the utmost importance. The present study attempts to present the epidemiological profile of the patients attending a peripheral referral institute of this state with head-neck pathologies and has undergone a histopathological examination of their lesions within a period of three years period (2016-18) based on the histopathological evidences. Materials and Methods The accumulated data regarding the aforesaid patients as per records of the histopathological reports available in the Department of Pathology was used as the primary material and the interrelation of different epidemiological parameters were studied using the statistical methods Results Six hundred and eighty seven cases from the head and neck region were analysed during this three-year period. Age range was from 3 years to 96 years with maximum cases in the age group of 20-29 years (16.1%). The Male: Female ratio in our study was 1.34:1 (Males 394, Females 293). In this study, 38.8% benign, 32.46% malignant, 25.32% inflammatory and 3.3% congenital cases were recorded. Maximum number of benign lesions was in the age group of 10-39 years. Malignancies were noted to be higher in ages 40 years and above. Squamous cell carcinoma was the most common malignancy observed. Conclusion  Specific data obtained like this from histopathological records is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.

scholarly journals Role of endoscopy in suspicion of atrophic gastritis with and without intestinal metaplasia in comparison to histopathology

2021 ◽  
Vol 84 (1) ◽  
pp. 9-17
Author(s):  
H Ibrahim ◽  
A Shams El-Deen ◽  
ZA Kasemy ◽  
M Saad ◽  
AA Sakr
Keyword(s):  
Atrophic Gastritis ◽  
Intestinal Metaplasia ◽  
Sensitivity And Specificity ◽  
Chronic Gastritis ◽  
Gastrointestinal Symptoms ◽  
High Sensitivity ◽  
High Specificity ◽  
Poor Correlation ◽  
Gastric Lesions ◽  
Low Sensitivity

Background and study aims : Atrophic gastritis (AG) and intestinal metaplasia (IM) are established premalignant gastric lesions. Many studies documented a poor correlation between esophagogastroduodenoscopy (EGD) and histopathological (HP) findings of precancerous gastric lesions. The aim was to bridge the gap between endoscopy and HP in detection of chronic gastritis, AG and IM. Patients and methods : a prospective single-center study involved 150 patients with endoscopic criteria of gastric lesions with upper gastrointestinal symptoms referred for upper GI endoscopy met the endoscopic criteria and classified according to HP of biopsies from targeted gastric lesions into chronic gastritis (GI), AG(GII) or IM(GIII). We correlated the endoscopic criteria of the 3 groups with the HP results. Results : (73males & 75 females) with ages ranged17-75 years and mean± SD was 41.96 ± 15.95. GI, GII &GIII were [42 patients (28%),82 patients (54.7%) and 26 patients (17.3%)], respectively. Diffuse gastric mottling was more common in GI (74.3%, P<0.001), visible submucosal vessels, gastric atrophy predominated in GII (75.6, 82.3 & 73.1% (P 0.005,0.4 & <0.01)), respectively. Whitish raised lesions were more specific in GIII (85.7%) (P<0.001). The sensitivity and specificity of endoscopic suspicion of chronic gastritis were (86&88% in GI), (87&85% in GII) and (54% &100% in GIII) (p-0.001). The logistic regression model for risk factors was χ2= 25.74 and 49.32, p < 0.001. Conclusion : Conventional endoscopy has high sensitivity and specificity for suspicion of chronic gastritis and AG, but low sensitivity and very high specificity for IM. Targeted biopsies may be valuable with image enhanced techniques.

PREVALENCE OF CARCINOMA GALLBLADDER IN PATIENTS OF CHOLELITHIASIS

2021 ◽  
pp. 1-3
Author(s):  
Mishra Braja Mohan ◽  
Mishra Sandeep ◽  
Bedbak Biswajeet
Keyword(s):  
Open Surgery ◽  
Histopathological Examination ◽  
Gall Stone ◽  
P Value ◽  
Age Group ◽  
Female Ratio ◽  
Carcinoma Gallbladder ◽  
Number Of Patients ◽  
Male Female Ratio ◽  
Surgery Department

Gall stone is the most common risk factor for carcinoma gall bladder. The aim of this study nds out the prevalence of malignancy in patients with Cholelithiasis. All the radiologically diagnosed cased of cholelithiasis underwent surgery were taken into consideration. All the cases of cholelithiasis operated of in General Surgery Department of VSSIMSAR, Burla were considered for study. The diagnosis conrmed by Ultrasonography /MRCP in Department of Radio diagnosis. Total numbers of patients operated are 347, out of which 279 undergone laparoscopic surgery, 58 cases undergone open surgery and 10 cases converted from laparoscopic to open surgery. Most number of patients belongs to age group 31-40, consisting of 32.85% of total number, followed by age group 41-50, and consisting of 25.07%. A female patient constitutes about 77.81 % of total number. Male: female ratio is 1: 3.5. The mean age of the patients of study group is 41 .71. Mean age of female patients is 41.09 and male is 43.88, p value 0.072 (no signicant deference between mean of female and male). The excised specimens sent for histopathological examination in Department of Pathology, VSSIMSAR, Burla. Out of 347 cases nine cases found to have carcinoma specically adenocarcinoma of gallbladder.

scholarly journals Histopathological spectrum of salivary gland lesions in rural India

2021 ◽  
Vol 11 (1) ◽  
pp. 1830-1836
Author(s):  
Deepu Mathew Cherian ◽  
Rahul M Jadhav ◽  
Shaikh Murtuza ◽  
Tooba Fatima ◽  
Kashinath S Bhople
Keyword(s):  
Salivary Gland ◽  
Rural Population ◽  
Wide Spectrum ◽  
Medical Science ◽  
Malignant Lesion ◽  
Female Ratio ◽  
Medical College ◽  
Female Predominance ◽  
Male Female Ratio ◽  
Malignant Lesions

Background: Salivary gland lesions are of a wide spectrum and affect all the major and minor salivary glands in varying proportions. This study, performed in a rural medical college in Maharashtra, India is intended to see the histopathologic spectrum of salivary gland lesions in the rural population and how it is related to the data from other parts of the country and of the world.  Materials and Methods: This is a retrospective study done in the Department of Pathology of a rural-based medical college, Indian Institute of Medical Science and Research, Warudi, Maharashtra, India for a period of 6 years, from January 2014 to January 2020. Age, sex, location of the lesion, gross and microscopic findings were noted.Results: A total of 71 lesions were received in the department of pathology during this period. Samples were received from age 11 years to 75 years. Female preponderance with a male: female ratio of 1:1.15 was seen. 57.7% (n=41) were benign, 15.5% (n=11) were malignant and the rest (n=19) were inflammatory in nature. A maximum number of lesions (50.7%) were detected in the Parotid gland. The most common lesion seen was Pleomorphic adenoma (36.62%, n=26) and the most common malignant lesion was Mucoepidermoid carcinoma.Conclusions: Present study showed benign and non-neoplastic lesions outnumbering the malignant lesions, with female predominance, and a low mean age for malignant lesions of 38.2years. Comparison with other studies within and outside India showed a similar pattern of distribution of salivary gland lesions in the rural population. 

Çocuklarda Brankiyal Yarık Anomalileri

2021 ◽  
Author(s):  
Orkhan Farzaliyev ◽  
Özlem Boybeyi Türer ◽  
Tutku Soyer ◽  
Feridun Tanyel
Keyword(s):  
Physical Examination ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Neck Mass ◽  
Fistula Tract ◽  
Radiological Findings ◽  
Recurrence Rates ◽  
Submandibular Region ◽  
Female Ratio ◽  
Male Female Ratio

INTRODUCTION: Objective: A retrospective study was planned to evaluate the clinical and radiological findings of childhood branchial anomalies together with the subclasses of the anomaly and to discuss the surgical results. Method: The medical records of the patients managed for branchial cleft anomaly between 2014 and 2019 were examined. Demographic features, clinical and radiological findings, surgical managements and outcomes were recorded. Results: Eighteen cases were included in the study. Median age of the cases was 5 years (1-14). Male/female ratio was 9/9. The complaints were discharge from the BC (n=13, 72%) and painless neck mass (n=3, 17%). The BC was at right side in 8 (44%), left side in 9 (%50) and bilateral in 1 case (6%). Physical examination revealed the presence of a fistula, and its orifice in 14 cases and cystic lesion was palpable in 4 cases. Ultrasound was performed in 9 cases (50%) and cyst could be detected in 3 of them. All cases were operated and step-ladder incision was used in 8 cases. The fistula tract was ended near to pharynx in 2, near to pretonsillar fossa in 10, submandibular region in 5, and external auditory tract in 1 case. Histopathological examination revealed inflammation in 2 cases and cartilage in 1 case. Stratified ciliary columnar and stratified squamous cell epithelium was detected in samples. Conclusion: Physical examination is the most important diagnostic method. The management is surgery and excision of whole lesion is important in preventing recurrences. Although using methylene blue is a guiding technique in surgical excision of tracts, the effect of its use on surgical outcome and recurrence rates is still debatable.

scholarly journals Safety of 0.1% topical tacrolimus in the treatment of vitiligo

2014 ◽  
Vol 13 (3) ◽  
pp. 255-259
Author(s):  
Samaresh Chandra Hazra ◽  
Nafiza Ahmed ◽  
Jagodish Chandra Ghosh
Keyword(s):  
Adverse Effect ◽  
Response Rate ◽  
Medical Science ◽  
Newly Diagnosed ◽  
Female Ratio ◽  
Topical Tacrolimus ◽  
Medical College ◽  
Male Female Ratio ◽  
Different Response ◽  
Cure Rates

Cure rates for vitiligo are significantly lower because of problems to different studies have reported different response rate and different adverse effect for the treatment of vitiligo. This study was conducted to evaluate the response rate and adverse effect of topical tacrolimus 0.1% ointment in the treatment of vitiligo patients in the department of Dermatology and venereology, Bangladesh Medical college (BMC), Dhaka from January 2010 to July 2010. In this clinical trial, 30 newly diagnosed vitiligo (focal and segmental) patients, aged between 10 to 50 years were assigned for therapy and to observe the response and adverse effect. Each individual lesion was treated with topical tacrolimus 0.1% ointment twice daily for three months. All the patients completed three months treatment and available for statistical analysis. The highest percentage 13(43.3%) was in the age of 11-20 years. Sex ratio revealed higher in case of female 18(60%), with a male-female ratio 1:1.5 and 5(16.67%) patients had vitiligo among their families. Repigmentation was observed in 8 (26.7%) subjects at the end of 4th week, 15 (50.1%) subjects at 8th week and 25 (83.3%) subjects after 12 weeks of therapy. 25 (83.33%) subjects did not complain any adverse effect (like pruritus, burning etc.) and 5 (16.67%) subjects were suffered from different adverse effect of drug, like pruritus observed in 2 (6.7%) subjects and burning in 6 (20%) subjects. This study found that tacrolimus 0.1% ointment to be safe in the treatment of vitiligo, with reduction in the number of vitiliginous spots by increased repigmentation significantly. DOI: http://dx.doi.org/10.3329/bjms.v13i3.19147 Bangladesh Journal of Medical Science Vol.13(3) 2014 p.255-259

scholarly journals Hansen's Neuritis Revisited – A Clinicopathological Study

2018 ◽  
Vol 09 (01) ◽  
pp. 042-055
Author(s):  
Navya Jaiswal ◽  
Shrijeet Chakraborti ◽  
Kashinath Nayak ◽  
Shivananda Pai ◽  
B. P. Shelley ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Nerve Biopsy ◽  
Skin Lesions ◽  
Common Finding ◽  
Diagnostic Challenge ◽  
Female Ratio ◽  
Tuberculoid Leprosy ◽  
Male Female Ratio ◽  
Uncommon Condition ◽  
Age Range

ABSTRACT Introduction: Leprosy affecting the nerve solely or with concomitant skin lesions is not an uncommon condition in clinical practice. It is responsible for extensive morbidity and often poses a diagnostic challenge. This study aims to highlight the clinicopathological features of Hansen's neuritis (HN). Materials and Methods: In this retrospective study, cases of histologically diagnosed HN, from January 2010 to July 2017, were reviewed in the light of clinical features, treatment history, and outcome. Results: There were 18 cases of HN which accounted for 3.97% of total nerve biopsy samples (n = 453) and 0.02% of total histopathology samples (n = 81,013). The male: female ratio was 5:1 in the cases of HN. Age range was 20–79 years with a mean age of 42.4 years (standard deviation: ±14.03). Among the HN cases, there were 13 cases of pure neuritic leprosy (61.1%). Mononeuritis multiplex was the most common finding in the nerve conduction study. Six (33.3%) cases exhibited histological features of borderline tuberculoid leprosy, followed by five (27.8%) cases of mid-borderline features, three (16.7%) cases each of borderline lepromatous and burnt-out HN, and one (5.6%) case of polar tuberculoid leprosy. Lepra bacilli were detected on Fite-Faraco stain in 44.4% cases. Conclusion: Diagnosis of HN depends on astute search for skin lesions, nerve thickening or tenderness, sensory or motor symptoms, histopathological examination, and demonstration of lepra bacilli.

scholarly journals Pulmonary hamartoma, a rare benign tumour of the lung - Case series

2014 ◽  
Vol 5 (3) ◽  
pp. 112-115 ◽  
Author(s):  
Ruchita Tyagi ◽  
Amamjit Bal ◽  
Divyesh Mahajan ◽  
Raje Nijhawan ◽  
Ashim Das
Keyword(s):  
Histopathological Examination ◽  
Tertiary Care ◽  
Medical Science ◽  
Lung Nodule ◽  
Case Series ◽  
Pulmonary Nodules ◽  
Solitary Pulmonary Nodules ◽  
Ct Guided ◽  
Female Ratio ◽  
Pulmonary Hamartoma

Introduction - Pulmonary hamartoma, with incidence of 0.25-0.32%, accounts for 6% of solitary pulmonary nodules. The role of radiology is limited as only 10-30% of cases show characteristic ‘popcorn’ calcification and Computed Tomography can detect approximately  50% of hamartomas. Hence cytological and/or histopathological examination is required to make a definitive diagnosis and exclude malignancy. Objective – As pulmonary hamartoma is a rare entity detected serendipitously on radiography and requires cytological and histopathological examination for confirmation of diagnosis, we present nine cases of solitary pulmonary nodules which were diagnosed as pulmonary hamartoma.  Methods - We retrospectively screened departmental records and slides and found nine cases of pulmonary hamartoma in our tertiary care institute. Three cases were diagnosed on CT guided Fine Needle Aspiration Cytology and four cases were diagnosed on histopathological examination of surgical specimens, over a period of 16 years (1997-2012). Two cases were incidentally discovered to have pulmonary hamartoma at autopsy.  Observations – The age of the patients ranged from 17-63 years (mean-46.3), with male to female ratio being 3.5:1. The size of the hamartoma varied from 0.4 – 1.3 cm, with mean diameter of 1 cm. Cytology showed mixture of bronchial epithelial cells, adipocytes and stromal fragments in fibromyxoid and chondroid background. Histopathology demonstrated lobules of cartilage and adipose tissue with intervening clefts lined by respiratory epithelium and mesenchymal stroma. Conclusion – Every solitary pulmonary nodule is not malignant. It is important to correctly diagnose pulmonary hamartoma, a rare, yet benign neoplasm presenting as a solitary lung nodule and distinguish it from malignancy.Asian Journal of Medical Science, Volume-5(3) 2014: 112-115 http://dx.doi.org/10.3126/ajms.v5i3.9243 

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