A CROSS SECTIONAL STUDY OF POLY CYSTIC OVARIAN SYNDROME (PCOS) AMONGST ADOLESCENT GIRLS IN LUCKNOW.

2021 ◽  
pp. 3-5
Author(s):  
Nidhi Johri ◽  
Priti Kumar

Background: Polycystic ovary disease is a common endocrine condition which is rapidly gaining epidemic proportions. Objectives: Current study was undertaken to screen adolescents and young unmarried girls aged 15-24 years for PCOS. Material and Methods: A cross-sectional hospital-based study was undertaken in Lucknow to assess the prevalence of polycystic ovarian syndrome (PCOS) among 389 adolescents and young girls aged 15-24 years. Among them, 300 completed all clinical, ultrasonography (USG), and biochemical investigations. Results: The prevalence of PCOS among them was 22.5% by Rotterdam and 10.7% by Androgen Excess Society criteria. Nonobese comprised 71.8% of PCOS diagnosed by Rotterdam criteria. Mild PCOS (oligomenorrhea and polycystic ovaries on USG) was the most common phenotype (52.6%). History of oligomenorrhea had a positive predictive value of 93.3% and negative predictive value of 86.7% to detect a possible case of PCOS. Hyperinsulinemia (serum insulin >15 μlU/mL) was present among 19.2% of diagnosed PCOS cases. Conclusion: The study demonstrates that PCOS is an emerging disorder during adolescence and screening could provide opportunity to target the group for promoting healthy lifestyles and early interventions to prevent future morbidities

Author(s):  
Budi Wiweko ◽  
Cynthia A. Susanto

Objective: To evaluate whether Anti Müllerian Hormone (AMH) can be used as a predictor of metabolic syndrome in Polycystic Ovarian Syndrome (PCOS).Methods: This cross-sectional study was conducted in Yasmin Clinic, Dr. Cipto Mangunkusumo General Hospital Jakarta between June and December 2012. Forty-one patients diagnosed with PCOSbased on Rotterdam Criteria were enrolled. Secondary were was taken from medical record..Results: A total of 22 subjects were involved in this study. Mean AMH level in the metabolic syndrome group is compared to the non-metabolic syndrome group (10.72 ± 6.23 ng/ml vs 7.97 ± 4.50ng/ml, p=0.12). AMH was strongly associated with HDL, triglyceride and insulin resistance (r-value of -0.29, 0.23, and 0.21 respectively, p < 0.05).Conclusion: AMH can be used as a predictor of metabolic syndrome in PCOS.[Indones J Obstet Gynecol 2017; 5-2: 83-86]Keywords: anti müllerian hormone, metabolic syndrome, polycystic ovarian syndrome


2018 ◽  
Vol 6 (9) ◽  
pp. 395-406
Author(s):  
Noura Mohammed Al Bassam ◽  
Sarah Ali ◽  
Syed Raziur Rahman

Introduction: Polycystic Ovarian Syndrome (PCOS) is a condition that affects a woman’s hormone levels and it is said to be the most common female syndrome. Affects between 4-8% of reproductive-aged women and is associated with reproductive, metabolic and psychological dysfunction. Methods: A Quantitative observational cross-sectional study, we recruited 350 students of Qassim University selected using random sampling according to the inclusive criteria (age between 18-25 years). An online questionnaire designed in Arabic to facilitate the data collection, and university students, participated voluntarily. Statistical data entry and analysis of results was performed using Microsoft Excel. Results: Our sample size was 350 Qassim University students whose ages were between 18-25 years. 71% (n=248) Students heard about the PCOS, 49% of them heard about the symptoms from other people (mother, sister, cousin, etc.).  The presence of the symptoms of PCOS among these students was as, the most common symptoms were Hair loss 74%, Mood swing 67%, Acne 61%, and the least common symptom was Voice change 8%.  The prevalence of the syndrome among the university students was found to be 12% of these 350 students suffer from PCOS (diagnosed). Conclusion: 71% of studens were aware about the Polycystic Ovary Syndrome. 12% of students suffered from PCOS. Most common symptoms reported was Irregular menstrual cycle, 87%, and the least common symptom was Voice change 13%. 62 % of the students who suffered from PCOS were taking treatments based on hormonal therapy and surgical intervention. Attitude and Practices showed misconceptions about PCOS, and a need for awareness.


2020 ◽  
Vol 27 (10) ◽  
pp. 2182-2186
Author(s):  
Roohi Jabbar ◽  
Rukhshan Khurshid ◽  
Uzma Jabbar ◽  
Mudassir Zia ◽  
Abeera Mazhar Siddiqui ◽  
...  

Objectives: The study was designed to find out the association of PCOS with insulin resistance and GLUT4. Study Design: Cross Sectional study. Setting: Outdoor Department of Sir Ganga Ram Hospital Lahore. Period: March 2016 to December 2016. Material & Methods: 37 PCOS women visited Outdoor Department of Sir Ganga Ram Hospital Lahore. Their age range was 25- 36 years. 20 ages matched medical staff of the Sir Ganga Ram Hospital, Lahore with no history of any disease were selected as control. Rotterdam’s criteria were used to confirm PCOS. Levels of circulating insulin, GLUT 4 and fasting glucose were estimated. Results: Mean age of PCOS patients and of controls was 30.55 and 29.00 years respectively. Values of BMI were insignificantly raised in PCOS in comparison to controls. Levels of circulating GLUT-4, fasting glucose, insulin and resistance of insulin were increased significantly in women with PCOS in comparison to the controls. Decreased ratio of glucose to insulin was seen in PCOS women in comparison to their controls. Conclusion: A good association of PCOS was observed with insulin mediated release of glucose transporter GLUT 4 and insulin resistance.


2020 ◽  
Author(s):  
Azam Azargoon ◽  
Majid Mirmohammadkhani ◽  
Sara Borjian

The diagnosis of polycystic ovary syndrome (PCOS) and metabolic syndrome (MS) in adolescents is clinically challenging. It is on the rise as consistent with the increasing trends in obesity rates. This study aimed to investigate the prevalence of PCOS in adolescents by the National Institutes of Health (NIH) criteria and compare the prevalence of insulin resistance (IR) and metabolic syndrome (MS) between obese (OB) and non-obese (NOB) adolescents with PCOS. This was cross-sectional research with multi-stage cluster random sampling. Participants were 15-18-year-old girls from high schools in Semnan, Iran. The ones who had a history of menstrual dysfunction underwent clinical and hormonal tests. From among a total of 900 participants, 74 girls (8.2%) had a history of menstrual dysfunction. The prevalence of PCOS was 6.44% by NIH criteria. The prevalence of abnormal glucose metabolism, MS, and IR in girls with PCOS were 8(13.7%), 6(10.3%), 24(41.4%), respectively. The OB-PCOS group with a mean BMI of 28.21±1.26 kg/m2 had a significantly greater prevalence of MS, high BP, waist circumference ≥88 cm, and higher IR than NOB-PCOS cases with a mean BMI of 20.54±2.97 kg/m2. Abnormal glucose metabolism was prevalent in adolescents with PCOS and occurred with equal frequency in OB and NOB PCOS groups. Obesity could worsen IR, MS, and some of the components of Mets in PCOS adolescents.


2021 ◽  
Author(s):  
Mahsa Yarjanli ◽  
shahideh Jahanian Sadatmahalleh ◽  
Negin Mirzaei ◽  
Khadijeh Azarbajani

Abstract Background: Polycystic ovary syndrome (PCOS) coexisting mood disorders along with a combination of aesthetic manifestations may have a detrimental effect on women's sexual function. Hence, different phenotypes of PCOS have different clinical and biochemical signs and symptoms. The aim of this study was to compare women's sexual function (SF) in different phenotypes of PCOS.Methods: This cross-sectional study was conducted on 364 women who met the Rotterdam diagnostic criteria to compare different PCOS phenotypes (A=95, B=78, C=95, and D=95). All patients were invited to fill out the female sexual function index (FSFI).Results: Significant differences were observed between the different phenotypes in terms of total score, sexual desire, arousal, lubrication, and satisfaction (P<0.001); however, no significant differences were found between them in the terms of pain (P>0.05) and orgasm (P>0.05). In addition, phenotype B had the lowest mean score of total FSFI (P<0.05).Conclusion: The results indicated that women's SF is significantly different in different PCOS phenotypes. It is concluded that in order to solve the SF problems of women with PCOS, different treatment and care measures should be considered according to the relevant phenotype.


Author(s):  
Tenkeu A. Udofia ◽  
Faosat O. Jinadu ◽  
Abimbola T. Ottun ◽  
Ayokunle M. Olumodeji

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine cause of infertility affecting about 1 in 10 women of reproductive age. This study determined the proportion of infertile women with PCOS and compared clinical and sonographic features in infertile women with PCOS and without PCOS.Methods: This was a prospective comparative cross-sectional study at the Lagos State University Teaching Hospital over a 6 month period. One hundred and fifty two infertile women were recruited and had trans-vaginal ultrasonography for the presence and absence of polycystic ovaries. The diagnosis of PCOS was made using the Rotterdam criteria with other relevant socio-demographic and clinical data noted in the study proforma. Student t and chi-square tests were used as appropriate.Results: The prevalence of PCOS among infertile women was 32.9%. The mean age of infertile women diagnosed with PCOS and without PCOS was 33±4.90 and 32.71±5.00 years, respectively. Women with PCOS had significantly higher BMI than women without PCOS. Increased ovarian volume, peripheral follicular distribution and increased stromal echogenicity were observed in 60%, 74% and 94% of women with PCOS on trans-vaginal ultrasound compared to 11.8%, 2% and 2% of women without PCOS, respectively.Conclusions: The prevalence of PCOS among infertile women is high. Clinical characteristics of women with PCOS and women without PCOS are similar except in their BMI and features that constitute the diagnostic criteria for PCOS.


2021 ◽  
Vol 15 (6) ◽  
pp. 1299-1301
Author(s):  
A. Malik ◽  
S. A H. Kazmi

Background: Polycystic syndrome (PCOS) is the most common endocrine disorder in the world affecting 8% of women. The main characters of PCOS are enlarged ovaries, chronic ovulation, menstrual cycles disturbance, androgen overdose, and insulin resistance leading to acne, hirsutism, and reproductive problems. Acne is a quite common dermatological condition in daily practice. Aim: To determine the association of acne vulgaris with polycystic ovarian syndrome in patients visiting the University of Lahore Teaching Hospital. Study design: Descriptive cross-sectional study. Place and duration of study: Dermatology Outpatient Department, University of Lahore Teaching Hospital Lahore from March 2019 to March 2020. Methodology: It was a descriptive cross-sectional study from March 2019 to March 2020 conducted at the Dermatology Out-patient Department, University of Lahore Teaching Hospital. All patients between the ages of 18 and 40, with acne vulgaris were included in the study. After obtaining informed consent, 101 women with acne vulgaris in I-IV (Indian stages), between the ages of 18-40 years, presented in the Department of Dermatology, University of Lahore Teaching Hospital, from March 2019 to March 2020, were selected for the study. Pregnant females, lactating mothers, and women on hormonal treatment (oral contraceptives or injections) were excluded from the study. A history of acne, oligomenorrhea, hirsutism, seborrhea, alopecia, acanthosis nigricans infertility, obesity and amenorrhea were taken. Weight and height were measured to calculate BMI. Data were collected in a special statistically tool and analyzed using SPSS-25. Results: A total of 101 women were examined having acne vulgaris issue. A total of 101 female were assessed and having history of acne vulgaris. Out of this, 33 were 18–23 years old, while 24 (23.4%) have ages 24–28 years. There were 18 (17.8%) patients who have 29–33 years old. while 38–40 years were 10 (9.9%) years old. Irregular menstrualcycle was reported 34.6% of the study population. As Perth WHO criteria, only 17% of the participants had BMI in normal weight range. The proportion of women, who were overweight and obese were 50.4% and 32.6% in the study population. Conclusion: Acne vulgaris has been identified as a serious skin disease found in all age groups. PCOS is more common among women with acne and obesity is a major risk factor for PCOS.


2020 ◽  
Vol 31 (2) ◽  
pp. 116
Author(s):  
Imanuel Far-Far ◽  
Anang Endaryanto ◽  
Retno Asih Setyoningrum ◽  
Gatot Soegiarto

<p class="Englishversionofabstract">The prevalence of allergic diseases has increased in the last decade. Therefore, precise and reliable in predicting allergy in children were needed. However, in daily practice, most misdiagnosis occurs because it is only based on a family history of allergy. This study aims to evaluate the chronicity, recurrence of symptoms with similar exposure, and family history of allergy to be used as a predictor of allergy in children with respiratory symptoms. Cross sectional study was conducted in children who referred to the Pediatric Allergy and Immunology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya from January 1st - July 31st 2019. Children with a suspected allergy who developed respiratory symptoms was included. The data was taken from standardized medical record. The sensitivity and specificity of the 3 characteristics of atopic with positive SPT were calculated. A total of 115 children were admitted and 109 children fulfill the inclusion criteria. Gender 60% male and 40% female. The most common group of age founded was age 5-&lt;10 years 39.4%, followed by 1-&lt;3 years (25.8%), 3-&lt;5 years (22.9%), 10 years 8.3%, and &lt;1 year (3.6%). Fifty-four patients (49.5%) fulfilled 3 characteristics of atopy and there were 64 patients (58.7%) with positive SPT results. The sensitivity, specificity, positive predictive value and negative predictive value were 81.3%, 95.6%, 96.3%, and 78.2%, respectively. The 3 characteristics of atopy have good sensitivity and specificity to predict allergy in children.</p>


2020 ◽  
Vol 20 (3) ◽  
pp. 323
Author(s):  
Hana Alzamil ◽  
Khawlah Aloraini ◽  
Reem AlAgeel ◽  
Aya Ghanim ◽  
Ruba Alsaaran ◽  
...  

Objectives: This study aimed to compare endocrinologists’ versus gynaecologists’ approaches in using the Rotterdam criteria to diagnose polycystic ovarian syndrome (PCOS). Methods: This cross-sectional study was conducted at Physiology Department, King Saud University, Riyadh, Saudi Arabia, between December 2017 and April 2018. A validated self-administered questionnaire in English was used to obtain information from endocrinologists and gynaecologists regarding their approaches to diagnosing PCOS. Each group’s diagnostic use of the Rotterdam criteria, association between years of experience and clinical decision-making, clinical features leading to diagnosis and considerations in the diagnosis of biochemical parameters that define hyperandrogenism were evaluated. Results: A total of 132 physicians were included in this study (response rate: 27%); 77 (58.3%) were endocrinologists and 55 (41.7%) were gynaecologists. Most of the respondents (79.5%) had ≤20 years of experience. A statistically significant difference was detected between the endocrinologists and gynaecologists (98.7% versus 81.8%; P = 0.001) in their consideration of hyperandrogenism in the diagnosis. The gynaecologists relied more on ovarian morphology than the endocrinologists did (76.4% versus 45.5%, P <0.0001). Physicians with more experience used ovarian ultrasonography more compared to those with less experience (P = 0.006). Conclusion: There was disparity in the diagnostic approaches of endocrinologists, who rely more on androgen levels for diagnosis of PCOS versus gynaecologists, who more frequently use an ovarian morphology assessment. Increased years of experience increased the rate of ultrasonography use for PCOS diagnosis in both groups.Keywords: Polycystic Ovary Syndrome; Gynecology; Endocrinology; Diagnosis; Hyperandrogenism; Hirsutism; Healthcare Disparities; Saudi Arabia.


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