scholarly journals ANTIMICROBIAL PROPERTIES OF LANTHANUM ALUMINATE NANOPARTICLES

2016 ◽  
Vol 3 (1) ◽  
pp. 1-5
Author(s):  
Gayathri S ◽  
Ranjithkumar R ◽  
Balaganesh A.S ◽  
Chandar Shekar B

The sol-gel route synthesized LA-NPs were tested for antimicrobial properties against different human pathogenic bacteria and fungi. The test organisms used were clinical isolates viz., Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, Klebsiella nemoniae and the human fungal pathogens like Candida albicans and Trichoderma viride. The LA- NPs achieved maximum activity against S. aureus compared with other three tested organisms such as S. pyogenes, E. coli and K. pneumonia. It also showed very good antimicrobial properties against studied fungi. At the concentration 1 mg/ml LA-NPs impregnated filter paper disk achieved maximum activity against human pathogen.




2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Iffat Naz

The present study is focused on the assessment of the antimicrobial activity of cerumen and antibiotics against bacteria isolated from ear pus samples. Thus, a total of 50 ear pus samples were collected from infected patients using sterile swabs and were screened using pure culture techniques. Total of 04 different bacterial isolates were identified while, the prevalence data revealed that Pseudomonas spp., were dominant (58%, n = 29) among isolated bacteria followed by Staphylococcus spp., (22%, n = 11), Escherichia coli (14%, n = 7) and Proteus spp., (6%, n = 3). Further, bioassay revealed that Pseudomonas spp., and Staphylococcus spp., were most sensitive to Clindamycin (94.73%) while displayed resistant to Ciprofloxacin and Ampicillin. Similarly, E. coli and Proteus spp., were most sensitive to Ciprofloxacin (92.8-95.21%) as compared to the other antibiotics. Moreover, antibacterial activity of cerumen was also assessed against test organisms and its maximum activity was observed against Pseudomonas spp., (90% equivalent to Clindamycin potency) and Staphylococcus spp., (60% equivalent to Amoxicillin potency) while least effective against E. coli (36%) and Proteus spp., (22%). Thus, it was concluded that the antibacterial activity of cerumen might be due to the presence of potential chemicals i.e. flavonoids and terpenoids.



2021 ◽  
Vol 11 (11) ◽  
pp. 2087-2096
Author(s):  
Obaid Albulym ◽  
Omer Kaygili ◽  
Mai S. A. Hussien ◽  
H. Y. Zahran ◽  
Mona Kilany ◽  
...  

This study reports a detailed analysis of the yttrium doping effects into hydroxyapatite (HAp) nano-structures at different amounts (e.g., 0, 1, 2.5, 5, 7.5, 10, and 15%) on the structural, spectroscopic, dielectric, and antimicrobial properties. For this purpose, seven HAp samples having the Y-contents mentioned above were prepared using the microwave-assisted sol-gel precipitation technique. The structure of synthesized samples was fully described via X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transforms infrared (FTIR). Raman spectroscopy and dielectric measurements were used to characterize the spectroscopic properties. Furthermore, the samples’ antimicrobial features have been assisted through the agar disk diffusion technique. This study showed that the crystallinity decreased with the adding of Y-ions inside the HAp matrix. The Y-contents have influenced the crystallite size, lattice parameters, dislocation density, lattice strain, and unit cell volume. The surface morphology is composed of the agglomerated smaller particles. Remarkable changes in the dielectric properties were observed with the adding of Y-ions. The alternating current conductivity obeys the Jonscher’s relation. Y-doped hydroxyapatite nanoparticles have a considerable inhibitory effect against bacteria and fungi (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans). The Y-doped hydroxyapatite nanoparticles are a promising material for bone cement engineering with a potential bio-activity



2007 ◽  
Vol 123 ◽  
pp. 123-130 ◽  
Author(s):  
Roberta Júnior Paulert ◽  
Marciel J. Smania Stadnik ◽  
Moacir G. Pizzolatti


2019 ◽  
Vol 7 (1) ◽  
pp. 9-15
Author(s):  
Hamid Beyzaei ◽  
Hadis Hosseini Moghadam ◽  
Ghodsieh Bagherzade ◽  
Reza Aryan ◽  
Mohammadreza Moghaddam-Manesh

Background: Design, identification, and synthesis of new antimicrobial agents along with preventive proceedings are essential to confront antibiotic-resistant pathogenic bacteria. Heterocyclic Schiff bases are biologically important compounds whose antimicrobial potentials have been proven to bacterial and fungal pathogens. Objectives: In this study, some quinoline Schiff bases were synthesized from condensation of 2-chloro3-quinolinecarboxaldehyde and aniline derivatives. Their inhibitory activities were evaluated against 6 gram-positive and 2 gram-negative bacterial pathogens. Methods: Disc diffusion, broth microdilution, and time-kill tests were applied according to the CLSI guidelines to determine IZD, MIC, and MBC values. Results: 2-Chloro-3-quinolinecarboxaldehyde Schiff bases could inhibit the growth of bacteria with IZDs of 7.5-19.8 mm, MICs of 256-2048 μg mL-1, and MBCs of 512 to ≥2048 μg mL-1. Conclusion: Moderate antibacterial effects were observed with heterocyclic Schiff bases. Complexation and structural changes can improve their antimicrobial properties.



Author(s):  
Shanmugam Abirami ◽  
Sudalaimani Dinesh Kumar ◽  
Athiappan Murugan

Synthetic dyes are hazardous to the environment and humans due to their toxic and recalcitrant nature. Hence, the present study attempts to produce eco-friendly dye from the sago industrial waste using S. marcescens SS1. The dye produced by the bacterial bioconversion of sago was characterized by GC-MS and obtained 13.423 acquisition time, which is similar to the standard prodigiosin. The effects of the dyeing parameters were optimized for Jute fabric using tannic acid as a pre mordant, the maximum uptake of dye was observed at 80 °C, pH 7, 60 mins with the K/S of 6.6. The minimum K/S value of 3.9 was observed at 65 °C, pH 3 in 45 min. Better colour fastness was observed in prodigiosin with mordant compared to without mordant. The antimicrobial activity of dyed fabric was tested against a few pathogenic bacteria and it showed maximum activity against P. aeruginosa. The dye extracted from S. marcescens SS1 prodigiosin was found to be an effective dyeing agent and also pose antimicrobial properties.



2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Sarita Manandhar ◽  
Shisir Luitel ◽  
Raj Kumar Dahal

The emergence and spread of antibiotic resistance, as well as the evolution of new strains of disease causing agents, are of great concern to the global health community. Effective treatment of a disease entails the development of new pharmaceuticals or some potential source of novel drugs. Commonly used medicinal plants of our community could be an excellent source of drugs to fight off this problem. This study is focused on exploring the antimicrobial properties of the plants that are commonly being used as traditional medicines. The antimicrobial potential of four different plant extracts was screened against twelve pathogenic microorganisms and two reference bacterial strains. Methanolic extracts of Oxalis corniculata, Artemisia vulgaris, Cinnamomum tamala, and Ageratina adenophora were subjected to a test of their antimicrobial properties by agar well diffusion method. The result indicated that most of the extracts exhibited antimicrobial properties. The highest potential was observed in the extract of O. corniculata against Escherichia coli, Salmonella Typhi, MDR Salmonella Typhi, Klebsiella pneumoniae, and Citrobacter koseri with zone of inhibition (ZOI) of 17 mm, 13 mm, 16 mm, 11 mm, and 12 mm, respectively. Oxalis corniculata also showed the highest MIC against test organisms. The methanolic extract of Artemisia vulgaris, Cinnamomum tamala, and Ageratina adenophora showed efficacy against Staphylococcus aureus. Ageratina adenophora also showed antifungal activity against Rhizopus spp. The experiment confirmed the efficacy of some selected plant extracts as natural antimicrobials and suggested the possibility of employing them in drugs for the treatment of infectious diseases caused by the test organisms.



2017 ◽  
Vol 57 (4) ◽  
pp. 427-437 ◽  
Author(s):  
S. H. S. Dananjaya ◽  
D. C. M. Kulatunga ◽  
G. I. Godahewa ◽  
Chamilani Nikapitiya ◽  
Chulhong Oh ◽  
...  


Biomedicines ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 62 ◽  
Author(s):  
James Melrose

This study reviewed aspects of the biology of two members of the glucosinolate family, namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties. Sinigrin and glucoraphanin are converted by the β-sulphoglucosidase myrosinase or the gut microbiota into their bioactive forms, allyl isothiocyanate (AITC) and sulphoraphanin (SFN) which constitute part of a sophisticated defence system plants developed over several hundred million years of evolution to protect them from parasitic attack from aphids, ticks, bacteria or nematodes. Delivery of these components from consumption of cruciferous vegetables rich in the glucosinolates also delivers many other members of the glucosinolate family so the dietary AITCs and SFN do not act in isolation. In vitro experiments with purified AITC and SFN have demonstrated their therapeutic utility as antimicrobials against a range of clinically important bacteria and fungi. AITC and SFN are as potent as Vancomycin in the treatment of bacteria listed by the World Health Organisation as antibiotic-resistant “priority pathogens” and also act as anti-cancer agents through the induction of phase II antioxidant enzymes which inactivate potential carcinogens. Glucosinolates may be useful in the treatment of biofilms formed on medical implants and catheters by problematic pathogenic bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus and are potent antimicrobials against a range of clinically important bacteria and fungi. The glucosinolates have also been applied in the prevention of bacterial and fungal spoilage of food products in advanced atmospheric packaging technology which improves the shelf-life of these products.



Author(s):  
Dilfuza Egamberdieva ◽  
Dilfuza Jabborova ◽  
Svetlana Babich ◽  
Sokhiba Xalmirzaeva ◽  
Kamaliddin Salakhiddinov ◽  
...  

AbstractIn traditional medicine of Uzbekistan, around 20% of herbal plants are used to treat various ailments, including diseases caused by pathogenic bacteria and fungi. Though conventional medicinal plants are common in Uzbekistan, many plant species potentially useful for new pharmaceuticals are less studied. They contain various biological compounds with antibacterial and antifungal activities, that could be developed into drugs. The search for novel antimicrobial compounds, especially against multidrug-resistant pathogens from aromatic and herbal plants is an essential scientific research line. However, the antimicrobial properties of several medicinally important plants from various countries are still unknown. This review aims to provide an up-to-date report on the antimicrobial activity of medicinal plants endemic to Uzbekistan widely used in traditional medicine.



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