scholarly journals Gerontostomatology: from science to clinical medicine (survey)

2020 ◽  
Vol 18 (3) ◽  
pp. 71-77
Author(s):  
A. K. Iordanishvili
Keyword(s):  
Temporomandibular Joint ◽  
Tooth Loss ◽  
Soft Tissues ◽  
Clinical Medicine ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Masticatory Muscles ◽  
Petersburg Institute ◽  
Hard Tissues ◽  
Dissertation Research

Aim of the study was, based on the analysis of dissertation research prepared in scientific laboratories and departments of the St. Petersburg Institute of Bioregulation and Gerontology, to present the contribution of the staff of this Institute to the development of modern gerontostomatology. Dissertation research carried out within the walls of the St. Petersburg Institute of Bioregulation and Gerontology in the field of gerontostomatology touched on the pathology of hard tissues and pulp of teeth, rehabilitation in case of tooth loss, periodontal diseases, oral mucosa, injuries and inflammatory diseases of the jaws and peri-maxillary soft tissues, as well as pathology temporomandibular joint and masticatory muscles in elderly and senile people.

A STUDY ON ASSOCIATION 0F TOOTH LOSS & PERIODONTAL DISEASE IN PATIENTS SUFFERING FROM DIABETES FROM BIHAR REGION

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Kumar Manish ◽  
Nikita Raman ◽  
Abhishek Gautam ◽  
Samir Jain ◽  
Prakash Chandra Jha ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Tooth Loss ◽  
Alveolar Bone ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Control Group ◽  
Diabetic Patients ◽  
Diabetes Group ◽  
The Individual ◽  
Tissue Attachment

Diabetes is one of the common diseases of modern times and one of the most common systemic disorder that is connected to periodontal disease. Periodontal diseases are bacterially induced chronic inflammatory diseases affecting the tissues surrounding and supporting the teeth. The lesion begins as gingivitis, an inflammation of the gingival tissues only, and may progress to periodontitis, where destruction of connective tissue attachment and alveolar bone can eventually lead to tooth loss. Hence based on above reported findings the present study was planned for study of prevalence of tooth Loss in Patients Suffering from Diabetes from Bihar Region. The present study was planned in Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar. Total 100 cases were enrolled in the present study. In the enrolled patients 50 cases were Diabetic and 50 were non-diabetic cases. The data generated from the present study concludes that periodontal disease increases in diabetes group than in control group. Thus, a diabetic patient should always see that he/she maintains his/her oral hygiene by following proper tooth brushing habits. Diabetics should take care to see that they get their teeth restored as early as possible, if decayed. They should follow the instructions given by the physician or the dietician for the intake of non-cariogenic diet. The prevention of periodontal breakdown in diabetic patients is mostly based on the education of the individual. Thus, patients should be informed about the importance of oral health for diabetics, and they should be taught that the main symptom of periodontal disease is gingival bleeding. Keywords: Tooth Loss, Diabetes, periodontal disease, bihar, etc

scholarly journals Effect of human adipose-derived regenerative cells on temporomandibular joint healing in immunodeficient rabbits

2019 ◽  
Vol 88 (1) ◽  
pp. 49-56
Author(s):  
Barbora Putnová ◽  
Pavel Hurník ◽  
Vladimír Jekl ◽  
Dušan Žiak ◽  
Vladimír Machoň ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Soft Tissues ◽  
Bone Remodelling ◽  
Healing Process ◽  
Cellular Level ◽  
Research Attention ◽  
Promising Tool ◽  
Hard Tissues ◽  
Rising Incidence ◽  
Regenerative Cells

Increasing research attention has focused on the use of stem cells (SCs) in regenerative and reparative medicine. Adipose-derived regenerative cells (ADRCs) are a relatively cheap and ethical source of SCs. Temporomandibular disorders (TMDs) have been reported with rising incidence over recent decades. The main aims of this study were to evaluate the effects of ADRCs application on the healing of both soft and hard temporomandibular joint (TMJ) tissues, and to assess the possible utilization of ADRCs in TMD treatment. We investigated the effects of human ADRCs on the healing of TMJ defects in immunodeficient rabbits. With no prior cultivation, ADRCs were applied to a surgically created defect in the cartilage of a rabbit TMJ. The healing process and inflammatory response were examined. Our results indicated that ADRCs supported repair processes in soft tissues. However, ADRC treatment induced a significant immune response in both soft and hard tissues, with hard tissues showing a higher level of bone remodelling. Non-differentiated ADRCs can be a promising tool for regenerative medicine of TMJ; however, deeper understanding of their effect on the cellular level is needed.

scholarly journals Assessing temporomandibular disorders: Mouthpiece design considerations

2018 ◽  
Vol 75 (8) ◽  
pp. 756-763
Author(s):  
Dino Bukovic ◽  
Igor Glavicic ◽  
Goran Dimitric ◽  
Miroslav Smajic ◽  
Bozana Radanovic ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Soft Tissues ◽  
Masticatory Muscles ◽  
Muscle Stiffness ◽  
Average Score ◽  
Posterior Teeth ◽  
Scuba Divers ◽  
Orofacial Region ◽  
Jaw Joint ◽  
Oral Screen

Background/Aim. Scuba diving is one of the sports with the fastest growing popularity. Nowadays doctors of dental medicine meet divers-patients in their offices more often. Treatment of these patients has some specific features that are related to difficulties in the temporomandibular joint, masticatory muscles and soft tissues of the oral cavity. A set of those complaints represent a condition called ?diver's mouth syndrome?. Most scuba divers complain of temporomandibular joint and the masticatory muscles pain; inadequate mouthpieces can exacerbate temporomandibular dysfunction (TMD) even when its symptoms are not present in everyday life. The aim of this research was to find a decent substitute for a fully customised mouthpiece, that are not present at our market, to discover the qualities of a good mouthpiece and establish prevalence of TMD among divers. Methods. This study included 30 scuba divers. Scuba divers filled out the questionnaire before diving, then dived twice with each of the 3 different commercial mouthpieces provided for this research (Mares Universal, Seac sub, Mares LiquidSkin (Universal Mares, Seac sub, Mares LiquidSkin). After diving, they filled out the second part of the questionnaire and so they performed an assessment of the mouthpiece and gave insight into the prevalence of TMD symptoms caused by using the mouthpiece. Results. According to the average score of satisfaction (the least present symptoms such as pain, fatigue, and numbness of the masticatory muscles and the jaw joint), this research proved Mares LiquidSkin mouthpieces to be the best out of the 3 commercial mouthpieces. For its use, average satisfaction score among participants was 7.07 (out of 10) and none of the divers reported jaw and muscle stiffness during and after the dive with this mouthpiece. The smallest percentage of participants reported pain in the orofacial region and discomfort while swallowing when used it in comparison with other mouthpieces. The anatomy and material of the mouthpieces turned out to be an extremely important factor. Conclusion. Several factors contribute to a good mouthpiece design; the choice of material, its elasticity and softness, the thickness and length of the interdental bite platform and the width of the oral screen that is inserted into the vestibule. The preferred material should be soft silicone. The interdental bite platforms should support the posterior teeth and the oral screen should fit the jaws and not be too wide.

Microbiological substantiation of application of phytopreparations in treatment of inflammatory periodontal diseases

2019 ◽  
Vol 24 (3) ◽  
pp. 196-202 ◽  
Author(s):  
S. A. Abdurakhmanova ◽  
G. S. Runova ◽  
M. S. Podporin ◽  
E. V. Tsareva ◽  
E. V. Ippolitov ◽  
...  
Keyword(s):  
Tooth Loss ◽  
Periodontal Diseases ◽  
Adult Population ◽  
Experimental Studies ◽  
Herbal Medicines ◽  
Growth Dynamics ◽  
Integrated Approach ◽  
Bacterial Populations ◽  
Streptococcus Constellatus ◽  
Urgent Task

Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became the main cause of tooth loss in adult population. Herbal medicines have a variety of pharmacological properties, so the development and introduction of new forms for the treatment of inflammatory periodontal diseases is an urgent task today.Purpose – experimental evaluation of effectiveness of the use of herbal medicines “Tonzinal” and “CM-1” in relation to the priority periodontal pathogenes.Materials and methods: in experimental studies, the basis for the experiment was the system for the cultivation of microorganisms in real time – the Revers-Spinner RTS-1 bioreactor. With the priority strains of periodontitis pathogens, the study of the growth dynamics of the culture was carried out in several parallels.Results: herbal medicines “CM-1” and “Tonsinal” has a multilateral therapeutic effect, exerting a diverse influence on the key stages of development of such bacterial populations as Aggregatibacter actinomycetemcomitans, Streptococcus constellatus, Candida albicans.Conclusion: tan integrated approach in the treatment of patients with inflammatory periodontal diseases is promising and will contribute to a more prolonged remission and increase the effectiveness of treatment. 

scholarly journals Temporomandibular Disorders and Bruxism Prevalence in a Portuguese Sample

2021 ◽  
Vol 5 (1) ◽  
pp. 37
Author(s):  
João Belo ◽  
André Almeida ◽  
Paula Moleirinho-Alves ◽  
Catarina Godinho
Keyword(s):  
Temporomandibular Joint ◽  
Temporomandibular Disorders ◽  
Temporomandibular Disorder ◽  
Masticatory Muscles ◽  
Diagnostic Aspects ◽  
Relevant Role

Temporomandibular disorder (TMD) encompasses a set of disorders involving the masticatory muscles, the temporomandibular joint and associated structures. It is a complex biopsychosocial disorder with several triggering, predisposing and perpetuating factors. In the etiology of TMD, oral parafunctions, namely bruxism, play a relevant role. The study of bruxism is complicated by some taxonomic and diagnostic aspects that have prevented achieving an acceptable standardization of diagnosis. The aim of this study was to analyze the prevalence of temporomandibular disorders and bruxism in a Portuguese sample.

scholarly journals Titanium Wear of Dental Implants from Placement, under Loading and Maintenance Protocols

2021 ◽  
Vol 22 (3) ◽  
pp. 1067
Author(s):  
Georgios Romanos ◽  
Gerard Fischer ◽  
Rafael Delgado-Ruiz
Keyword(s):  
Adverse Effects ◽  
Inflammatory Response ◽  
Dental Implants ◽  
Soft Tissues ◽  
Loading Conditions ◽  
Material Change ◽  
Implant Placement ◽  
Implant Abutment ◽  
Hard Tissues ◽  
Titanium Nanoparticles

The objective of this review was to analyze the process of wear of implants leading to the shedding of titanium particles into the peri-implant hard and soft tissues. Titanium is considered highly biocompatible with low corrosion and toxicity, but recent studies indicate that this understanding may be misleading as the properties of the material change drastically when titanium nanoparticles (NPs) are shed from implant surfaces. These NPs are immunogenic and are associated with a macrophage-mediated inflammatory response by the host. The literature discussed in this review indicates that titanium NPs may be shed from implant surfaces at the time of implant placement, under loading conditions, and during implant maintenance procedures. We also discuss the significance of the micro-gap at the implant-abutment interface and the effect of size of the titanium particles on their toxicology. These findings are significant as the titanium particles can have adverse effects on local soft and hard tissues surrounding implants, implant health and prognosis, and even the health of systemic tissues and organs.

scholarly journals A Protocol for the Use of a Combined Microvascular Free Flap with Custom-Made 3D-Printed Total Temporomandibular Joint (TMJ) Prosthesis for Mandible Reconstruction in Children

2021 ◽  
Vol 11 (5) ◽  
pp. 2176
Author(s):  
Krzysztof Dowgierd ◽  
Rafal Pokrowiecki ◽  
Maciej Borowiec ◽  
Marcin Kozakiewicz ◽  
Dominika Smyczek ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Soft Tissues ◽  
Total Joint Replacement ◽  
Speech Development ◽  
Functional Requirements ◽  
Immediate Reconstruction ◽  
Congenital Deformities ◽  
Custom Made ◽  
Masticatory System

Extended postoperative mandibular reconstructions due to orofacial disease involving the temporomandibular joint (TMJ) in immature patients remain a challenge as a result of ongoing growth, which is usually affected by the disease and treatment. Current reconstructive techniques based fully on alloplastic total joint replacement fail to meet fully the anatomical and functional requirements for the masticatory system and speech development. Fourteen children aged 12.6 ± 2.6 with tumors or congenital deformities affecting the mandible and TMJ were included in the study. Radical surgical treatment according to our own protocol was performed through microvascular anastomotic flap reconstruction of the soft tissues and bones, together with total TMJ custom replacements. Follow-up lasted 2–6 years. During the follow-up, increases in the mandible body (13% growth) and ramus (12% growth) were observed, both of which were related (p < 0.001). This is the first report concerning the immediate reconstruction of the mandible with ramus and total TMJ in children and adolescents that combines a free vascularized graft and total individual prosthesis of the TMJ. The presented technique enabled optimal function of the TMJ, growth of the mandible, and further rehabilitation of the patients. The technique was demonstrated to be safe, reliable, and provide good functional and cosmetic outcomes.

Non-primate Lentiviral Vector Administration in the TMJ

2004 ◽  
Vol 83 (1) ◽  
pp. 65-70 ◽  
Author(s):  
S. Kyrkanides ◽  
P. Kambylafkas ◽  
J.H. Miller ◽  
R.H. Tallents
Keyword(s):  
Temporomandibular Joint ◽  
Reporter Gene ◽  
Soft Tissues ◽  
Lentiviral Vector ◽  
Retrograde Transport ◽  
Lentiviral Vectors ◽  
Treatment Method ◽  
Joint Space ◽  
Nerve Fibers ◽  
Temporomandibular Joint Disorders

Gene therapy is emerging as a novel treatment method for the management of temporomandibular joint disorders. The aim of this investigation was to study the effects of lentiviral vectors on the temporomandibular joint. Consequently, we injected into the articular joint space a defective feline immunodeficiency virus capable of infecting dividing as well as terminally differentiated cells with the reporter gene lacZ, the expression of which was studied by means of PCR, X-gal histochemistry, and β-galactosidase immunocytochemistry. Our results showed successful transduction of hard and soft tissues of the temporomandibular joint. Interestingly, a subset of primary sensory neurons of the ipsilateral trigeminal ganglion also stained positive for the reporter gene, presumably following uptake of the lentiviral vector by peripheral nerve fibers and retrograde transport to the nucleus. These findings suggest that lentiviral vectors can potentially serve as a platform for the transfer of anti-nociceptive genes for the management of temporomandibular joint pain.

scholarly journals Temporomandibular joint dysfunction in Parkinson's Disease: an integrative literature review

Revista CEFAC ◽  
2017 ◽  
Vol 19 (5) ◽  
pp. 702-711 ◽  
Author(s):  
Taysa Vannoska de Almeida Silva ◽  
Maria das Graças Wanderley de Sales Coriolano ◽  
Carla Cabral dos Santos Accioly Lins
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Temporomandibular Joint ◽  
Myofascial Pain ◽  
Mouth Opening ◽  
Signs And Symptoms ◽  
Masticatory Muscles ◽  
Therapeutic Interventions ◽  
Temporomandibular Joint Dysfunction ◽  
Language Restriction

ABSTRACT Temporomandibular joint dysfunction is a set of disorders involving the masticatory muscles, temporomandibular joint and associated structures. It is known that the progression of motor symptoms in Parkinson's disease is an indication that these people are more prone to the development of this dysfunction. Thus, this study aims to investigate the signs and symptoms of temporomandibular dysfunction in people with Parkinson's disease. The search was performed in the databases: MEDLINE/ PubMed, LILACs, CINAHL, SCOPUS, Web of Science and PEDro, without timing or language restriction. Specific descriptors were used for each database and keywords, evaluated by the instruments: Critical Appraisal Skill Program and Agency for Health care and Research and Quality. A total of 4,209 articles were found but only 5 were included. After critical analysis of the methodology of the articles, one did not reach the minimum score required by the evaluation instruments, thus, it was excluded. The selected articles addressed, as signs and symptoms of temporomandibular joint dysfunction, the following: myofascial pain, bruxism, limitation of mouth opening, dislocation of the articular disc and asymmetry in the distribution of occlusal contacts. Further studies are needed in order to determine the relationship between cause and effect of the analyzed variables, so as to contribute to more specific and effective therapeutic interventions.

scholarly journals Clinical and cytological characteristic of a condition of the oral cavity at pregnant women with various types of a diabetes mellitus

2016 ◽  
Vol 65 (6) ◽  
pp. 45-51 ◽  
Author(s):  
Ludmila Yu Orekhova ◽  
Anna A Aleksandrova ◽  
Ludmila A Aleksandrova ◽  
Ramila S Musaeva ◽  
Gulrukhsor Kh Tolibova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Pregnant Women ◽  
Inflammatory Diseases ◽  
Type I Diabetes ◽  
Periodontal Diseases ◽  
Diabetes Mellitus Type 1 ◽  
Control Group ◽  
Type I ◽  
Liquid Based Cytology

Introduction. More and more researches dedicated to the communication of diseases of the oral cavity of pregnant women with diabetes. It is proved that the intensity of caries and inflammatory periodontal diseases (gingivitis and periodontitis) increase significantly during pregnancy, while the presence of comorbidities, such as diabetes, increase these indexes.Aim. The aim of the work was to study the dental status of pregnant women with diabetes.Materials and methods. The study compared women with gestational diabetes mellitus, type 1 diabetes, and type 2 diabetes, to a control group of pregnant women without diabetes. In addition to clinical research methods, liquid-based cytology of the contents of the gingival sulcus was performed.Results. The results of clinical and laboratory studies have shown that inflammatory diseases of periodontium and teeth within pregnant women with diabetes are more common than within the pregnant women without this disease. It should be noted that the frequency of occurrence and severity of these diseases in the pregnant women with type I diabetes is higher than in the other groups.Conclusion. Pregnant women with diabetes are at risk for dental disease and require more attention from dentists, endocrinologists and obstetricians. The use of liquid-based cytology method helps in the diagnosis of inflammatory periodontal diseases.

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