scholarly journals UJI AKTIVITAS ANTIJERAWAT DAN KARAKTERISTIK FISIK EMULGEL MINYAK ATSIRI DAUN JERUK PURUT (Citrus hystrix DC.) DENGAN BASIS GEL HPMC TERHADAP Propionibacterium acne

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Anggun Hari Kusumawati

Tests were conducted antiacne activity emulgel of essential kaffir lime leaves oils (Citrus hystrix DC.) against Propionibacterium acne. Antiacne activity assays performed by agar diffusion method at a concentration of 1%, 2%, 4%, and 8%. The results showed that of the kaffir lime leaves oil can inhibit the growth of P.acne. The greatest inhibitory regions shown the higher concentration of kaffir lime leaves oils, then the inhibitory of growth inhibition area P.acne increasingly widespread of 8% > 4% > 2% > 1%. Relationships increased concentration of essential lime leaves oils in the emulgel dosage effect on physical properties such as chemical emulgel pH, viscosity, and the power spread. From the test results it is known that the higher the concentration of oils in the preparation kaffir lime leaves emulgel the pH and viscosity of the lower F0> F1> F2> F3> F4, while increasing power spread F0 <F1 <F2 <F3 <F4. The storage period of emulgel preparation effect on the physical characteristics of the stocks as organoleptic properties, pH, and viscosity. The longer the period of storage of the organoleptic properties emulgel will change the pH value drops, and viscosity values also decreased significantly. Key words : P.acne, Kaffir lime leaves oil, Emulgel Telah dilakukan uji aktivitas antijerawat dari emulgel minyak atsiri daun jeruk purut (Citrus hystrix DC.) terhadap Propionibacterium acne. Pengujian aktivitas antijerawat dilakukan dengan metode difusi agar pada konsentrasi 1%, 2%, 4%, dan 8%. Hasil menunjukkan bahwa minyak atsiri daun jeruk purut dapat menghambat pertumbuhan P.acne. Dari hasil uji aktivitas antijerawat yang ditunjukkan dengan semakin tinggi konsentrasi minyak atsiri daun jeruk purut maka diameter daerah hambat pertumbuhan P.acne semakin luas 8%>4% >2%>1%. Hubungan peningkatan konsentrasi minyak atsiri daun jeruk purut dalam sediaan emulgel berpengaruh terhadap sifat fisika kimia emulgel seperti pH, viskositas, dan daya sebar. Dari hasil uji diketahui bahwa semakin tinggi konsentrasi minyak atsiri daun jeruk purut dalam sediaan emulgel maka pH dan viskositas semakin rendah F0>F1>F2>F3>F4, sedangkan daya sebar semakin meningkat F0<F1<F2<F3<F4. Masa penyimpanan sediaan emulgel berpengaruh terhadap karakteristik fisik sediaan seperti sifat organoleptis, nilai pH, dan viskositas. Semakin lama masa penyimpanan maka sifat organoleptis emulgel akan berubah, nilai pH semakin turun, dan nilai viskositas juga mengalami penurunan yang signifikan. Kata Kunci : P.acne, minyak atsiri daun jeruk purut, emulgel

Author(s):  
Ahmad Irsyad Aliah ◽  
Wahyuni Wahyuni ◽  
Nurjannah Bachri

A research on the inhibition of formula gel test ethanol extract of leaves of mulberry (Morus alba L.) as an anti-acne against bacteria Propionibacterium acne. This study uses a gel formulation made using mulberry leaf extract (Morus alba L.), which aims to determine the inhibition of antibacterial gel mulberry leaf extract (Morus alba L.) against the bacteria Propionibacterium acne. Gel made three dosage concentrations of 2%, 4% and 6%. Testing inhibition of antibacterial gel agar diffusion method. Test Antibacterial inhibition obtained by looking at the clear zone in the medium and measured using calipers. The results showed that the inhibition of antibacterial gel formulation with a concentration of 2%, 4% and 6% showing that inhibiting bacterial activity.


2002 ◽  
Vol 13 (3) ◽  
pp. 155-161 ◽  
Author(s):  
Brenda Paula Figueiredo de Almeida Gomes ◽  
Caio Cezar Randi Ferraz ◽  
Morgana Eli Vianna ◽  
Pedro Luiz Rosalen ◽  
Alexandre Augusto Zaia ◽  
...  

The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide in combination with several vehicles against some microorganisms commonly isolated from root canals. Antimicrobial activity was determined by the agar diffusion method. Stainless-steel cylinders were placed on each inoculated agar medium. The test medicaments and their controls were placed inside the cylinders. The zones of growth inhibition were measured and recorded after incubation for each plate and the results were analyzed statistically (ANOVA). The in vitro antimicrobial effects of the medications were ranked from strongest to weakest as follows: Ca(OH)2 + CMCP + glycerine, Ca(OH)2 + CMCP, Ca(OH)2 + glycerine, Ca(OH)2 + anesthetic, Ca(OH)2 + saline, Ca(OH)2 + H2O, Ca(OH)2 + polyethyleneglycol. The pastes with oily vehicles showed significantly larger mean zones of inhibition compared to those with aqueous or viscous vehicles. It was concluded that diffusion and antimicrobial activity of calcium hydroxide were affected by the type of vehicle used.


2020 ◽  
Vol 2 (1) ◽  
pp. 1-9
Author(s):  
Dwi Kurniawati Sambodo ◽  
Lisa Erie Yani

     Half of the world's population has been affected by dandruff, especially those aged 15 to 50 years. Dandruff is one of the problems on the scalp with common symptoms of scales (exfoliation of dead skin), itching of the scalp and redness around the scalp. Dandruff can be caused by an oily scalp, hormones or fungus. One of the fungi that cause dandruff is Candida albicans. Based on research that has been done, secondary metabolite compounds of methanol extract of peada fruit peel which is a pure white compound in the form of powder are identified as alkaloid compounds. In general, alkaloids can be used as an antifungal. Anti-dandruff shampoo is a dosage that is often used daily and can be used to treat and prevent scalp from excessive dandruff where this shampoo contains active antifungal agents which are effective as an anti-dandruff. Pedada fruit was extracted using multilevel maceration method with methanol as a solvent. Pedada fruit extract shampoo is formulated with variations in extract concentration into 3 formulas. Shampoo was tested for physical properties and effectiveness of anti-dandruff using the Kirby-Bauer Diffusion method with PDA media. From the results obtained it can be concluded that the physical properties of the three formulas of pedada fruit extract shampoo (Sonnerratia caseolaris L) include organoleptic, pH , high foam , cycling test, and viscosity produced good physical properties in accordance with the standard test of the physical properties of shampoo, however Homogeneity test results show that formula III shampoo is less homogeneous. All three shampoo formulas are effective as anti-dandruff against the fungus Candida albicans.


2018 ◽  
Vol 10 (4) ◽  
pp. 147 ◽  
Author(s):  
Agung Fitri Kusuma ◽  
Marline Abdassah ◽  
Bobby Ellyas Valas

Objective: The objective of this study was to design a product of anti-acne gel containing Citrus aurantifolia fruit juice as an effective antibacterial to treat acne caused by Propionibacterium acne and Staphylococcus epidermidis using carbopol as a gelling agent.Methods: The fresh juice of C. aurantifolia fruit was obtained by juicer and pasteurized for 30 min at 65-70 °C. The minimum inhibitory concentration (MIC) of the fruit juice was determined using the microdilution method. Then, carbopol in different concentration was incorporated in a gel base formula to obtain a stable gel base. The fresh juice in different formulas (F1, F2 and F3) was evaluated for 28 d. The color, pH and viscosity of each formula were observed. In addition, the antibacterial potency of each formula was analyzed using the agar diffusion method against both tested bacteria. Results: The citrus MIC values of both test bacteria showed different results, 20-40 % v/v for P. acne and 5-10 % v/v for S. epidermidis. The MIC values were converted into in vivo concentration and the resulted concentrations for each formula were 25, 50 and 75 % v/v. For supporting the formula, the most stable base gel was achieved using carbopol 1 % as the gelling agent. Among three formulas, the anti-acne gel formula containing 75 % fruit juice with carbopol 1% was the best formula based on the physical and microbiological parameter.Conclusion: Thus, it was concluded that the antiacne gel of fruit juice of C. aurantifolia with carbopol as a gelling agent could produce the effective and stable gel of anti-acne product.


2019 ◽  
Vol 7 (3) ◽  
pp. 234
Author(s):  
Remus B Maradou ◽  
Fitje Losung ◽  
Remmy EP Msngindaan ◽  
Rosita AJ Lintang ◽  
Wilmy E Pelle ◽  
...  

Sponge is one component of coral reefs that has the potential as a bioactive compound but has not been widely used. This study was directed to obtain some spongy crude extracts from the Salibabu waters of the Talaud Islands, determine the antibacterial activity of some crude extruded sponges and compare the antibacterial activity of the sponge fraction against E. coli and S. aureus test bacteria. The results of identification of sponges were found in three species consisting of: Siphonodictyon sp., Ircinia sp., Dysidea sp. The antibacterial activity of crude extract, water, methanol and hexane fractions using agar diffusion method with E. coli and S. aureus test bacteria. The crude extract of siphonodictyon sp and the water fraction of this extract show the highest antibacterial activity. Key words: Spons, Antibacterial, E. coli. S. aureus


2021 ◽  
Vol 5 (2) ◽  
pp. 21
Author(s):  
Ety Jumiati ◽  
Abdul Halim Daulay ◽  
Nurhayati Nurhayati

<p><strong><em>Abstract. </em></strong><em>Research has been carried out which aims to determine the manufacture and physical properties of gypsum panels in the manufacture of gypsum panels for home interiors using banana midrib waste which is converted into fiber. Variations in the composition of mixing gypsum flour with banana midrib fiber include: Samples (A: 0%:100%) , (B: 2%:98%), (C: 4%:96%), (D: 6%:94 %), (E: 8%: 92%</em><em>)</em><em>, and (F: 10%: 90%) with a FAS of 0.5. The physical test parameters include: Density, Water absorption, and Thickness expansion. From the test results obtained gypsum panels that are The best is in sample B which has a density value = 1.19 g/cm</em><em><sup>3</sup></em><em>, water absorption value = 24%, a thickness expansion value = 2.53%, which has complied with SNI 01-4449-2006 on the ceiling board.</em><em></em></p><p><strong><em> </em></strong></p><p><strong><em>Key words:</em></strong><em> Gypsum panels, banana midrib, and gypsum flour.</em><em></em></p>


Author(s):  
Ahmad Irsyad Aliah ◽  
Wahyuni Wahyuni ◽  
Nurjannah Bachri

A research on the inhibition of formula gel test ethanol extract of leaves of mulberry (Morus alba L.) as an anti-acne against bacteria Propionibacterium acne. This study uses a gel formulation made using mulberry leaf extract (Morus alba L.), which aims to determine the inhibition of antibacterial gel mulberry leaf extract (Morus alba L.) against the bacteria Propionibacterium acne. Gel made three dosage concentrations of 2%, 4% and 6%. Testing inhibition of antibacterial gel agar diffusion method. Test Antibacterial inhibition obtained by looking at the clear zone in the medium and measured using calipers. The results showed that the inhibition of antibacterial gel formulation with a concentration of 2%, 4% and 6% showing that inhibiting bacterial activity.


TAPPI Journal ◽  
2014 ◽  
Vol 13 (9) ◽  
pp. 51-60
Author(s):  
DENNIS VOSS ◽  
HANS-JOACHIM PUTZ ◽  
SAMUEL SCHABEL

The need for deinking mills to reduce their fresh water consumption has resulted in higher loads of various contaminants in the process water. Lower recovered paper quality also leads to higher contamination levels in the mills. This higher load has an influence on achievable target brightness. The objective of the work was to determine and explain the main reasons for relatively poor deinked pulp quality or poor deinking potential based on the influence of recovered paper composition and process water quality. The process water parameters significantly affect the deinking potential of recovered paper. The test results showed the negative effects of increased water hardness. For standard recovered paper mixtures, flotation selectivity is higher with increasing flotation pH-value. Good results were realized for standard recovered paper with low hardness, low surface tension, and high pH-value. The results for recovered paper containing flexo newsprint could be slightly improved with low hardness, low surface tension, and low pH-value. The results of the test program using design of experiments showed interacting effects of pH-value and surface tension on luminosity and flotation selectivity.


2014 ◽  
Vol 6 (1) ◽  
pp. 35 ◽  
Author(s):  
Rizka Karima

There’s so many pal solid waste or palm empty fruit bunches, but the utilization is not maximized, this research its to optimized utilization of palm solid waste to be wood vinegar and want to know the composition physical properties and chemical properties of wood vinegar from palm empty fruit bunches. Total yield of wood vinegar from palm empty fruit bunches its 15,94 % and total yield of charcoal its 64,58 %. GCMS result showing chemical properties from wood vinegar of burning < 100oC its obtained 19 compound and burning >100 oC its obtained 6 compound. The result physichal properties testing from crued wood vinegar its obtained specific gravity 1,0005 and 1,0010, pH value are 3,233 and 3,186, TAT content are 9,36 % and 11,12 %, phenol content its 0,44 %. The result physical properties testing from wood vinegar which has decolorizatin by activated carbon its obtained specific gravity are 0,9987 and 0,999, pH value are 3,036 and 3,012, TAT content are 8,29 % and 9,27 % and phenol content its 0,01 %.Keywords: palm bunches, wood vinegar, liquid smoke


Author(s):  
Kyoung- Sun Seo ◽  
Seong Woo Jin ◽  
Seongkyu Choi ◽  
Kyeong Won Yun

The antibacterial activity of three Cupressaceae plants (Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa) was tested against three bacteria using the agar diffusion method. The ether and ethylacetate fraction of crude methanol extract from the three plants showed potent antibacterial activity against the tested microorganisms. The result showed that Staphylococcus aureus revealed the most sensitivity among the tested bacteria. Thujaoccidentalisether fraction and Thujaorientalis hexane fraction exhibited the highest antibacterial activity against Staphylococcus aureus. E. coli was shown the highest MIC values compared to the other two tested bacteria, which indicates the lowest antibacterial activity against the bacterium. This study promises an interesting future for designing a potentially active antibacterial agent from the three Cupressaceae plants.


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