scholarly journals Therapeutic Adherence among Chronic Kidney Disease Patients under Hemodialysis in Selected Hospitals of Kathmandu Valley

2020 ◽  
Vol 10 (2) ◽  
pp. 55-62
Author(s):  
Kopila Luitel ◽  
Apsara Pandey ◽  
Bimala Kumari Sah ◽  
Takma KC
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Public Health Problem ◽  
Structured Interview ◽  
Mean Difference ◽  
Morbidity And Mortality ◽  
Kathmandu Valley ◽  
Cross Sectional ◽  
Therapeutic Adherence ◽  
Adherence To Diet

Introduction: Chronic Kidney Disease (CKD) is an emergent public health problem in Nepal. Hemodialysis is the best treatment for this disease to reduce morbidity and mortality. Therapeutic adherence is crucial factor that influences morbidity and mortality among patients under hemodialysis. The objective of the study was to find out the therapeutic adherence among CKD patients under hemodialysis in selected hospitals of Kathmandu valley. Methods: Descriptive cross-sectional study design was adopted. Altogether 164 patients with CKD under hemodialysis were selected by using non-probability purposive sampling technique. Data were collected through face to face interview using structured interview schedule. Frequency, percent, mean and standard deviations were used for data analysis. Nonparametric Kruskal Wallis test and Mann Whitney U test were applied to measure the mean difference in therapeutic adherence among CKD patients under hemodialysis according to selected variables. Results: Therapeutic adherence levels were 33.5%, 62.8% and 3.7% for good, satisfactory and unsatisfactory respectively. Concerning about hemodialysis, 92.7% respondents had good, 6.1% had satisfactory and 1.2% had unsatisfactory level of adherence to hemodialysis. Furthermore, it was found that 29.9%, 1.8 % and 87.8% respondents had good; and 59.1%, 42.1% and 9.1% had satisfactory level of adherence to diet, fluid and medicine respectively. The results showed that therapeutic adherence was statistically significant with mean difference according to sex (p=0.009), duration of hemodialysis (p=0.001), total session of hemodialysis (p=0.001) and providing health information by dietician and other hemodialysis patients (p=0.001). Conclusion: Therapeutic adherence was found to be satisfactory but adherence to fluid intake is still unsatisfactory. It is recommended that regular education and counseling should be provided in order to increase level of therapeutic adherence.

scholarly journals Risk factors for chronic kidney disease: a hospital based cross sectional study from Visakhapatnam

2018 ◽  
Vol 5 (9) ◽  
pp. 3909
Author(s):  
Sindhura Moparthi ◽  
Madhavi Seepana ◽  
Devi Madhavi Bhimarasetty
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Data Entry ◽  
Public Health Problem ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Dialysis Unit

Background: Chronic kidney disease (CKD) is being increasingly recognised as a leading public health problem. In India, given its population >1 billion, the rising incidence of CKD is likely to pose major problems for both healthcare and the economy in future years. Diabetes and hypertension are strong predictors for development and progression of chronic kidney disease. The objective of the study was to assess risk factors for chronic kidney disease among patients undergoing dialysis in King George Hospital (KGH), Visakhapatnam.Methods: This is an observational descriptive cross sectional study done in dialysis unit in KGH. A total of 100 patients were selected out of 141 registered CKD patients by simple random sampling technique. Study is done in the month of October- November 2015. A pretested semi structured schedule was administered. Informed written consent was taken from the patients. MS excel 2007 was used for data entry. Data was analysed by SPSS trial version 20. Categorical data was analysed by Chi square test.Results: Among 100 study subjects 72 were females and 28 were males. 91% of the CKD patients were Hypertensive, among whom 73.6% were males and 26.4% were females. This difference was not found to be statistically significant (p=0.446). 22% of the CKD patients were Diabetic, among whom 81.8% were males and 18.2% were females.Conclusions: Better understanding of the role of risk factors in CKD is needed. Large community based cross sectional studies are needed to study in detail about CKD risk factors. 

scholarly journals Status of Chronic Kidney Disease Patients Registered in National Kidney Center, Banasthali, Kathmandu

2015 ◽  
Vol 1 (4) ◽  
pp. 19-23 ◽  
Author(s):  
D Mishra ◽  
P Koirala
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Preventive Measures ◽  
Public Health Problem ◽  
Medication Cost ◽  
Cross Sectional ◽  
Average Patient ◽  
The Mean ◽  
Cross Sectional Design ◽  
The Needy

Chronic kidney disease is a worldwide public health problem. In Nepal, Chronic kidney disease patients are increasing and the management of this disease is very expensive compared to other chronic diseases? We assessed the socioeconomic status of chronic kidney disease patients registered in National Kidney Centre, Banasthali, Kathmandu. The study used descriptive cross sectional design. Ninety six samples were collected between 15- 31 October, 2012.The mean age of the patients was 47 years, with almost half of the patients (46%) from 41-60 years age group. Among the patients, 65 % were male, 85% were married, 80% were literate, 57% were past smoker and 75% were drinker and 59% were from Kathmandu valley. Likewise, most of them were Newar, work as housewife as the main occupation. One third (37%) had to sell their property for the treatment. On an average patient spent Rs.240000 per year in dialysis. Similarly, medication cost was Rs.180000 and transplantation cost was Rs.500000 to 1000000. Preventive measures of the disease and subsidy in the treatment will be beneficial for the needy people. DOI: http://dx.doi.org/10.3126/jmmihs.v1i4.11997Journal of Manmohan Memorial Institute of Health Sciences Vol. 1, Issue 4, 2015Page : 19-23 

scholarly journals MDRD, CKD-Epi and Creatinine Clearance with 24-Hour Urine Collection Results in Patients with Chronic Kidney Disease

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Siti Nurul Hapsari ◽  
Leonita Anniwati
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Creatinine Clearance ◽  
Clinical Pathology ◽  
Public Health Problem ◽  
Urine Collection ◽  
Global Public Health ◽  
Pathology Laboratory ◽  
Cross Sectional ◽  
Method Of Calculation

Kidney disease is a global public health problem, affecting over 750 million people worldwide. Glomerular Filtration Rate(GFR), which is calculated by measuring the creatinine clearance with 24-hour urine collection (CC) can be inaccurate due toimproper urine collection, causing the need for an easier and accurate method of calculation. This study was anobservational analytical cross-sectional research using consecutive retrospective sampling. Samples were data of patientswith Chronic Kidney Disease (CKD) who underwent CC test at the Clinical Pathology Laboratory of the Dr. Soetomo HospitalSurabaya during September-October 2018. Data were compared with the results of Cockcroft-Gault (CG), MDRD, andCKD-Epi formula, and were analyzed using the one-sample Kolmogorov-Smirnov test, paired T-test, and Wilcoxon SignedRank test. Correlation of CC results with CG, MDRD, and CKD-Epi results was tested with Spearman's rho and Bland Altmantest. The difference test of CC with CG, MDRD, and CKD-Epi showed results of (p=0.000), (p=0.194), and (p=0.468),respectively. There were significant differences between CC compared to CG, but not MDRD and CKD-Epi. There was amoderate correlation between CG, MDRD, CKD-Epi, and CC with r=0.529; 0.448, and 0.463, respectively. The mostcompatible formula was CKD-Epi. The measurement of GFR with CC correlated with CG, MDRD, and CKD-Epi; therefore, theycould be used as an alternative method to calculate GFR. Further experiments using an exogenous marker should beperformed to determine a suitable eGFR formula according to the degree of damage to the kidney.

scholarly journals Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China

2019 ◽  
Vol 16 (22) ◽  
pp. 4383 ◽  
Author(s):  
Andong Ji ◽  
Chunlei Pan ◽  
Hongxia Wang ◽  
Zhezhen Jin ◽  
Joseph H. Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Eastern China ◽  
Public Health Problem ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Associated Risk Factors

Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD.

scholarly journals Prevalence of Chronic Kidney Disease and Its Related Risk Factors in Elderly of Southern Iran: A Population-Based Study

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Leila Malekmakan ◽  
Parviz Khajehdehi ◽  
Maryam Pakfetrat ◽  
Alireza Malekmakan ◽  
Hamideh Mahdaviazad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Problem ◽  
Public Health Problem ◽  
Fars Province ◽  
Age Group ◽  
Cross Sectional ◽  
Southern Iran ◽  
Related Risk

Aim. The prevalence of chronic kidney disease (CKD) as a serious public health problem is growing in the elderly. This study aimed to assess CKD prevalence and its related risk factors in elderly population of Fars province. Methods. In this cross sectional study a total of 1190 elderly people are enrolled, and demographic and medical data were obtained. Data were analyzed by SPSS, and P of less than 0.05 was considered as statistically significant. Results. Prevalence of CKD stages III–V was 27.5% in the 60–69 years age group, 36.5% in the 70–79 years age group, and 40% in the ≥80 years age group. The prevalence of CKD increased with ageing in both men and women. Female gender was the strongest risk factor for CKD. Conclusions. Prevalence of CKD in elderly is high in Southern Iran, which has become an important health problem while it can be prevented or delayed in progression.

scholarly journals Association of Hypertension and Chronic Kidney Disease in Population Aged ≥18 Years Old

2021 ◽  
Vol 5 (3) ◽  
pp. 137
Author(s):  
Rizka Ramadhanti ◽  
Helda Helda
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Research ◽  
Public Health Problem ◽  
Secondary Data ◽  
P Value ◽  
Global Public Health ◽  
Prevalence Odds Ratio ◽  
Cross Sectional ◽  
Basic Health

Background: Chronic kidney disease (CKD) is a global public health problem, due to the increasing prevalence and incidence of kidney failure, poor prognosis, and required high costs for its treatment. Hypertension as the dominant risk factor for CKD also has a high prevalence which keep increasing in DKI Jakarta. This study aimed to determine the association between hypertension and the incidence of CKD in people aged ≥18 years old in DKI Jakarta Province.Materials and method: This was a quantitative research with an analytic cross-sectional study design. The data source used was secondary data obtained from Basic Health Research (Riset Kesehatan Dasar/Riskesdas) 2018. There were 7,141 samples that matched the inclusion and exclusion criteria.Results: The proportion of CKD and hypertension in people aged ≥18 years old in DKI Jakarta Province were 0.5% and 16.6%, respectively. There was a significant association between hypertension and CKD with a prevalence odds ratio (POR) of 3.140 (95% CI: 1.527-6.453) after being adjusted by the age variable. Several other characteristics such as age (POR = 3.912; 95% CI: 1.932-7.918), diabetes mellitus (POR = 3.412; 95% CI: 1.405-8.285), heart disease (POR = 7.323; 95% CI: 3.158- 16.982), and physical activity (POR = 2.324; 95% CI: 1.148-4.703) were also significantly associated with the incidence of CKD.Conclusion: Someone who has hypertension has 3.14 times (95% CI: 1.527-6.453; p-value = 0.002) chance of suffering from CKD compared to someone who does not have hypertension after being controlled by the confounding variable, age.Keywords: chronic kidney disease, hypertension, DKI Jakarta, Basic Health Research 2018

scholarly journals Study of hematological profile in patients with chronic kidney disease

2019 ◽  
Vol 7 (1) ◽  
pp. 11
Author(s):  
Gautam Panduranga ◽  
Ugendhar Perla
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Iron Deficiency ◽  
Transferrin Saturation ◽  
Public Health Problem ◽  
In Vitro Tests ◽  
Moderate Degree ◽  
Important Public Health Problem ◽  
Cross Sectional ◽  
Ckd Stage

Background: Chronic Kidney Disease (CKD) with its high prevalence, morbidity and mortality, has become an important public health problem. The incidence and prevalence of CKD is increasing worldwide, including India. CKD is associated with a variety of hematological abnormalities, include anaemia, infections and bleeding diathesis. Anaemia is the most consistent hematological abnormality and is associated with poor quality of life and poor cardiovascular outcomes.Methods: A hospital based cross-sectional observational study was done to detect the prevalence of haematological abnormalities, correlation of anaemia with CKD stage and evaluation of iron deficiency. Newly diagnosed CKD (stages 3 to 5) patients were included in this study. Presence of anaemia (Hb%, haematocrit, MCV, peripheral smear), iron deficiency (TSAT, serum ferritin), thrombocytopenia, leucocyte count and coagulation abnormalities (PT, APTT) in different stages of CKD were studied.Results: All the subjects in study group had anaemia which was normocytic and normochromic and of moderate degree in most patients. The severity of anaemia progressed with stage of the disease. Iron deficiency was significantly prevalent (52% in the study population, with transferrin saturation (TSAT) <20%). WBC count was not significantly altered. There was mild thrombocytopenia in a few patients. Bleeding time or other in vitro tests of platelet function were not measured. The coagulation parameters, PT and APTT, were not significantly altered.Conclusions: All CKD patients should be screened for iron deficiency anaemia for its early treatment and to decrease morbidity.

scholarly journals Awareness Regarding Chronic Kidney Disease Among Adults in a Hospital of Siddharthanagar Municipality

2021 ◽  
Vol 9 (02) ◽  
pp. 61-65
Author(s):  
Sulochana Ghimire ◽  
Gita Neupane ◽  
Chanda Sah
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Awareness Level

INTRODUCTION: Chronic kidney disease (CKD) has been recognized as a leading public health problem worldwide. Early detection and management of the risk factors of CKD is helpful for its prevention and reduction of burden caused by it. This study aimed to find out the awareness regarding chronic kidney disease among adults in a hospital of Siddharthanagar Municipality. MATERIAL AND METHODS: Hospital based descriptive cross-sectional study was used to find out the awareness regarding chronic kidney disease among 165 adults attending Medical out patient department of Universal College of Medical Sciences, Bhairahawa, Rupandehi, Nepal from July 11 to July 25, 2021. Descriptive and inferential statistics were used to assess the awareness level and its association with different socio-demographic variables. RESULTS: The findings of the study showed that 57.6% of respondents had low level of awareness regarding chronic kidney disease. Respondents have high awareness on risk factors of chronic kidney disease whereas respondents have relatively low awareness on meaning and clinical features of chronic kidney disease. CONCLUSION: On the basis of findings, it is concluded that more than half of the respondents have low awareness level regarding chronic kidney disease so an effort should be made to improve the awareness regarding chronic kidney disease for early identification and management of chronic kidney disease.

HUBUNGAN EFIKASI DIRI DENGAN KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS

2018 ◽  
Vol 5 (2) ◽  
pp. 56-63
Author(s):  
Abdul Wakhid ◽  
Estri Linda Wijayanti ◽  
Liyanovitasari Liyanovitasari
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Self Efficacy ◽  
Healing Process ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Kolmogorov Smirnov

Background: Self efficacy can optimize the quality of life of clients who undergo the healing process due to chronic diseases. Individuals with higher self-efficacy move their personal and social resources proactively to maintain and improve the quality and length of their lives so that they experience a better quality of life. Objectives: the purpose of this study was to find the correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency. Metode: This type of research was descriptive correlation with cross sectional approach. The samples in this study more 76 people with total sampling technique. The data collection tool for self efficacy was measured by General Self-Efficacy scale, for quality of life with WHOQoL-BREF. Statistical test used Kolmogorov-smirnov. Result: The result showed that self efficacy in patients with chronic kidney disease was mostly in moderate category (53,9%), quality of life in patients with chronic kidney disease was mostly in good category (68,4%). There was a correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency, the result obtained p-value of 0.000 <α (0,05). Suggestion: Patients with chronic kidney disease can maintain good quality of life by helping to generate positive self-esteem and high self efficacy.

scholarly journals Elevated alanine aminotransferase and low aspartate aminotransferase/alanine aminotransferase ratio are associated with chronic kidney disease among middle-aged women: a cross-sectional study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Hirotaka Ochiai ◽  
Takako Shirasawa ◽  
Takahiko Yoshimoto ◽  
Satsue Nagahama ◽  
Akihiro Watanabe ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Alcoholic Fatty Liver ◽  
Relationship Of

Abstract Background Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) to ALT ratio (AST/ALT ratio) have been shown to be related to non-alcoholic fatty liver disease or insulin resistance, which was associated with chronic kidney disease (CKD). However, it is unclear whether ALT and AST/ALT ratio are associated with CKD. In this study, we examined the relationship of ALT and AST/ALT ratio to CKD among middle-aged females in Japan. Methods The present study included 29,133 women aged 40 to 64 years who had an annual health checkup in Japan during April 2013 to March 2014. Venous blood samples were collected to measure ALT, AST, gamma-glutamyltransferase (GGT), and creatinine levels. In accordance with previous studies, ALT > 40 U/L and GGT > 50 U/L were determined as elevated, AST/ALT ratio < 1 was regarded as low, and CKD was defined as estimated glomerular filtration rate < 60 mL/min/1.73 m2 and/or proteinuria. Logistic regression model was used to calculate the odds ratio (OR) and 95% confidence interval (CI) for CKD. Results “Elevated ALT and elevated GGT” and “elevated ALT and non-elevated GGT” significantly increased the OR for CKD when compared with “non-elevated ALT and non-elevated GGT” (OR: 2.56, 95% CI: 2.10–3.12 and OR: 2.24, 95% CI: 1.81–2.77). Compared with “AST/ALT ratio ≥ 1 and non-elevated GGT”, “AST/ALT ratio < 1 and elevated GGT” and “AST/ALT ratio < 1 and non-elevated GGT” significantly increased the OR for CKD (OR: 2.73, 95% CI: 2.36–3.15 and OR: 1.68, 95% CI: 1.52–1.87). These findings still remained after adjustment for confounders. Conclusions Elevated ALT was associated with CKD regardless of GGT elevation. Moreover, low AST/ALT ratio was also associated with CKD independent of GGT elevation.

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