scholarly journals Dengue fever in the Indian subcontinent: an overview

2010 ◽  
Vol 5 (04) ◽  
pp. 239-247 ◽  
Author(s):  
Ummar Raheel ◽  
Muhammad Faheem ◽  
Mohammad Nasir Riaz ◽  
Naghmana Kanwal ◽  
Farakh Javed ◽  
...  

The Indian Subcontinent has emerged as a scene of many mosquito-borne infectious diseases, including malaria and dengue fever. After the 1990s, the rate of malaria declined owing largely to preventive measures, but at the same time dengue fever (DF) and dengue hemorrhagic fever (DHF) were increasing in the region. Outbreaks were recorded in all countries of the Indian Subcontinent with India, Pakistan, Bangladesh and Sri Lanka on the forefront and suffering from the largest number of cases and deaths. We discuss annual cases of DF/DHF in these four countries and possible factors involved in DF outbreaks. We also discuss prevalent serotypes in this region where data suggest the emergence of DEN2 and DEN3 as the most dominant and lethal serotypes. Climate is an important factor influencing DF outbreaks, and rainfall, temperature and humidity play a pivotal role in DF outbreaks. Finally the economic impact of DF/DHF cases is discussed showing that direct and indirect economic loss due to DF/DHF reaches millions of USD each year.

2011 ◽  
Vol 6 (07) ◽  
pp. 551-554 ◽  
Author(s):  
Ritu Karoli ◽  
Jalees Fatima ◽  
Zeba Siddiqi ◽  
Khursheed I Kazmi ◽  
Amit R Sultania

Introduction: Dengue viral infections are among the most important mosquito-borne diseases of the Indian subcontinent and have become a major global public health concern. Spread of disease has led to increased recognition of atypical manifestations apart from the classical clinical features of dengue infection. Methodology: A cross-sectional study of admitted patients suspected to have dengue infection was conducted during the monsoon and post-monsoon seasons in the year 2010. Patients who had serological confirmation of dengue infection were classified according to World Health Organization definitions of dengue fever and dengue hemorrhagic fever. Clinical and biochemical parameters were compared between the two groups. Results: Out of 356 patients with suspected dengue fever enrolled in the study, 138 (39%) had serologically confirmed dengue infection. Eighty (58%) patients were males and 58 (42%) were females. Ninety-six (70%) patients had classical dengue fever while 42 (30%) had dengue hemorrhagic fever. The most common symptoms were headache (105, 76%), abdominal pain (87, 63%), vomiting (80, 58%), rash (36, 26%), and cutaneous hypersensitivity (22, 16%). Hemorrhagic manifestations were present in 55 (40%) patients. Atypical manifestations were recorded. Notably, 14% of patients had neurological involvement and 4% had acute hepatic failure. Overall mortality was 6% and all fatal cases were due to multi-organ failure. Conclusion: Dengue infection poses a huge burden to the health-care system; its spectrum ranges from mild self-limiting illness to severe fatal disease. It can have varied and multi-systemic manifestations which can go unrecognized. Clinicians should have a high index of suspicion for atypical manifestations.


2005 ◽  
Vol 72 (6) ◽  
pp. 786-791 ◽  
Author(s):  
DANIELLE V. CLARK ◽  
MAMMEN P. MAMMEN ◽  
ANANDA NISALAK ◽  
VIRAT PUTHIMETHEE ◽  
TIMOTHY P. ENDY

Author(s):  
Leena H. Bajrai ◽  
Sayed S. Sohrab ◽  
Thamir A. Alandijany ◽  
Mohammad Mobashir ◽  
Muddassir Reyaz ◽  
...  

Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi, or parasites. Although many of them are permentantly hazardous, a number of them live in and on our bodies and they are normally harmless or even helpful. Under certain circumstances, some organisms may cause diseases and these infectious diseases may be passed directly from person to person or via intermediate vectors including insects and other animals. Dengue virus and Streptococcus pneumoniae are the critical and common sources of infectious diseases. So, it is critical to understand the gene expression profiling and their inferred functions in comparison to the normal and virus infected conditions. Here, we have analyzed the gene expression profiling for dengue hemorrhagic fever, dengue fever, and normal human dataset. Similar to it, streptococcus pneumoniae infectious data were analyzed and both the outcomes were compared. Our study leads to the conclusion that the dengue hemorrhagic fever arises in result to potential change in the gene expression pattern, and the inferred functions obviously belong to the immune system, but also there are some additional potential pathways which are critical signaling pathways. In the case of pneumoniae infection, 19 pathways were enriched, almost all these pathways are associated with the immune system and 17 of the enriched pathways were common with dengue infection except platelet activation and antigen processing and presentation. In terms of the comparative study between dengue virus and Streptococcus pneumoniae infection, we conclude that cell adhesion molecules (CAMs), MAPK signaling pathway, natural killer cell mediated cytotoxicity, regulation of actin cytoskeleton, and cytokine-cytokine receptor interaction are commonly enriched in all the three cases of dengue infection and Streptococcus pneumoniae infection, focal adhesion was enriched between classical dengue fever — dengue hemorrhagic fever, dengue hemorrhagic fever—normal samples, and SP, and antigen processing and presentation and Leukocyte transendothelial migration were enriched in classical dengue fever —normal samples, dengue hemorrhagic fever—normal samples, and Streptococcus pneumoniae infection.


2022 ◽  
Vol 99 (12) ◽  
pp. 51-56
Author(s):  
N. A. Rozanova ◽  
M. A. Sayfullin ◽  
N. N. Zvereva ◽  
V. E. Larichev ◽  
Ya. E. Grigorieva ◽  
...  

The article describes a clinical case of concurrent infectious diseases - dengue hemorrhagic fever and mycoplasma pneumonia in a patient who came back from the area endemic for dengue fever. Further, the patient was diagnosed with clostridial colitis which was the complication. Clinical, laboratory, and radiological parameters used in the diagnosis of diseases were evaluated.


2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wawan Kurniawan

ABSTRAK  Latar belakang: Demam Berdarah Dengue (DBD) disebabkan oleh virus Dengue dapat menyebabkan kematian. Pencegahan DBD yang dianggap paling tepat adalah Pemberantasan Sarang Nyamuk (PSN). Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan pengendalian vektor Demam Berdarah pada siswa sekolah dasar terhadap Maya Index di Majalengka. Metode: Penelitian ini menggunakan desain quasi experiment (pretest-posttest control group design). Sebanyak 4 sekolah terpilih sebagai kelompok intervensi dan 4 sekolah lainnya sebagai kontrol. Subyek penelitian adalah siswa kelas IV-VI yang terdiri dari 171 siswa pada kelompok intervensi dan 163 pada kelompok kontrol. Instrumen yang digunakan adalah formulir pemantauan jentik berkala. Hasil: Jumlah rumah dengan kategori Maya Index tinggi berkurang dari 27,5% menjadi 9,4%. Terjadi penurunan angka BRI kategori tinggi pada kelompok intervensi dari 20,5% menjadi 1,8%. Pada kelompok kontrol tidak terjadi penurunan angka BRI kategori tinggi (22,1%), sebaliknya terjadi penurunan kategori rendah dari 34,4% menjadi 3,7%. Tidak terjadi penurunan angka HRI pada kelompok intervensi maupun kontrol. Kesimpulan: Pelatihan pengendalian vektor Demam Berdarah dapat menurunkan nilai BRI dan Maya Index, tetapi tidak berpengaruh terhadap nilai HRI. Tidak adanya perubahan nilai HRI menunjukkan bahwa kebersihan dan sanitasi lingkungan merupakan faktor yang berpengaruh terhadap probabilitas kejadian demam berdarah. Kata Kunci : Demam Berdarah, Maya Index, pelatihan, pengendalian vektor   ABSTRACT Background: Dengue Hemorrhagic Fever (DHF) caused by Dengue virus could cause death. The most appropriate prevention of Dengue is eradication of mosquito nests (PSN). This study aims to determine the effect of Dengue vector control training on elementary students towards Maya Index in Majalengka. Method: This study used quasi-experimental design (pretest-posttest control group design). A total of 4 schools were selected as intervention groups and 4 other schools as controls. The subjects were students in grades IV-VI consisting of 171 students in the intervention group and 163 in the control group. The instrument used was periodic larva monitoring form. Results: The number of houses with a high Maya Index category in the intervention group decreased from 27.5% to 9.4%. There was a decrease in the high BRI category in the intervention group from 20.5% to 1.8%. In the control group, there was no decrease in the high BRI category (22.1%), on the contrary, there was a decrease in the low category from 34.4% to 3.7%. There was no decrease in HRI rates both of intervention or control groups. Conclusion: Dengue Fever vector control training could decrease the value of BRI and Maya Index, but does not affect the value of HRI. The absence of changes in HRI  indicate that environmental hygiene and sanitation are factors that influence the probability of dengue fever occurrence. Keywords: Dengue Hemorrhagic Fever, Maya Index, training, vector control


Author(s):  
OJS Admin

Globally, dengue is an emerging serious public health problem with a million infections occurring annually including significant number of dengue hemorrhagic fever cases.


Author(s):  
Radityo Prasetianto Wibowo ◽  
Wiwik Anggraeni ◽  
Tresnaning Arifiyah ◽  
Edwin Riksakomara ◽  
Febriliyan Samopa ◽  
...  

 Background: Indonesia has 150 dengue cases every month, and more than one person dies every day from 2017 to 2020. One of the factors of Dengue Hemorrhagic Fever (DHF) patients dying is due to the late handling of patients in hospitals or clinics. Health Office of Malang Regency recorded 1,114 cases of DHF that occurred during 2016, and the number of patients room available is limited. Therefore, Malang Regency is used as a case study in this research.Objective: This study aims to make a dashboard to display the predictions, visualize the distribution of DHF patients, and give mitigation recommendations for handling DHF patients in Malang Health Office.Methods: This study used the Business Intelligence (BI) Development method, which consists of two main phases, namely the making of Business Intelligence and the use of Business Intelligence. This research used the making of the BI phase, which consists of four stages, which are BI development strategies, identification and preparation of data sources, selecting BI tools, and designing and implementing BI. In the Extract, Load, and Transform process, this study used essential transformation and forecast.Results: BI method has succeeded in building the dashboard. The dashboard displays the visualization of Dengue Hemorrhagic Fever predicted results, detail of Dengue Fever Patient number, Dengue Fever patient trends per year and predictions 2 Monthly patient, and mitigation recommendation for each Community Health Office.Conclusion: We have built the BI Dashboard using the BI development method. It needs some treatment to get better performance. These are improving ETL performance using data virtualization technology, considering the use of cloud computing technology, conducting further evaluations by understanding the critical success factors to determine the level of success and weaknesses.


2020 ◽  
Vol 102 (5) ◽  
pp. 943-950 ◽  
Author(s):  
Hisham Ahmed Imad ◽  
Weerapong Phumratanaprapin ◽  
Benjaluck Phonrat ◽  
Kesinee Chotivanich ◽  
Prakaykaew Charunwatthana ◽  
...  

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