scholarly journals Difference between early clinical features of swine origin A H1N1 influenza corfirmed and not confirmed infection in Mexico

2011 ◽  
Vol 6 (04) ◽  
pp. 302-310 ◽  
Author(s):  
Monica Rodríguez-Valero ◽  
Hector Manuel Prado Calleros ◽  
Gerardo Arturo Bravo Escobar ◽  
Rafael Ricardo Valdez Vázquez ◽  
Rafael Figueroa Moreno ◽  
...  

Introduction: The Swine Origin A H1N1 Influenza Virus (SOIV) pandemic emerged in April 2009 affecting people and health-care systems worldwide. This study examined the differences among the early clinical features presented in confirmed SOIV cases, those who tested negative for SOIV infection, fatalities, and hospitalized cases. Methodology: We reviewed 1,024 initial medical records of patients presenting with acute respiratory symptoms who attended the respiratory emergency room of a general hospital in Mexico and had a confirmatory test for influenza AH1N1 by RT-PCR from April to December 2009. Results: Out of 1,024 cases, 457 (44%) were men with a mean age of 31±17 years; however, of these, SOIV confirmed cases were younger (26±8, p=0.000). SOIV infection was confirmed in 36% of the patients. Most (%?) cases presented mild infection, 20% of the patients required hospitalization, and 0.09% patients died. Asthma was more frequent in confirmed cases (p=0.028). Presence of COPD, systemic arterial hypertension, and diabetes mellitus was significant in confirmed hospitalized cases. Pulmonary rales, wheezing, and sudden symptom onset were more frequent and statistically significant in confirmed patients. Influenza-like illness was more frequent in confirmed cases (p=0.049).  Conclusions: This study presents one of the largest series of the new SOIV infection confirmed by RT-PCR reported. This infection is frequently mild and affects mainly young adults. Sudden symptoms onset, pulmonary rales, and wheezing are early features of this infection. Asthma, COPD, systemic arterial hypertension, and diabetes mellitus should be identified to identify potentially severe and fatal cases. ILI helps distinguish SOIV infection.


2021 ◽  
Vol 11 (33) ◽  
pp. 270-279
Author(s):  
Letícia Penariwê Sousa Wa Rovêdenê ◽  
Marise Ramos de Souza ◽  
Marlene Andrade Martins ◽  
Letícia Palota Eid ◽  
Marcos Antonio Nunes de Araujo ◽  
...  

A hipertensão arterial sistêmica (HAS), diabetes mellitus (DM), sedentarismo e síndrome metabólica afetam a saúde indígena. Este estudo objetivou identificar hipertensos e diabéticos na etnia Xavante, Mato Grosso. A amostra foi de 50 indígenas, caracterizados quanto ao sexo, idade, escolaridade, renda, estado civil e número de filhos. Fez-se a anamnese e avaliação clínica, com antecedentes de DM e/ou HAS, uso de medicações tradicionais ou não. Usaram-se tensiômetro digital de pulso e um glicosímetro capilar. Fez-se a análise com os testes qui-quadrado, Pearson, Kruskal wallis, t de Student, Coeficiente de correlação de Pearson e ANOVA. Um terço dos participantes recebiam até um salário mínimo; 22% eram compatíveis com pré-diabetes e 26% diabéticos; a HAS esteve em uma média de 122,5 (±14,5) por 79,8 (±9,4) mmHg. Houve relação significativa entre a renda, estado civil, idade e presença de filhos, com os dados clínicos e os aspectos multifatoriais de risco.Descritores: Indígena, Hipertensão Arterial, Diabetes Mellitus. Tracking chronic disease in an indigenous communityAbstract: Systemic arterial hypertension (SAH), diabetes mellitus (DM), physical inactivity and metabolic syndrome affect indigenous health. This study aimed to identify hypertensive and diabetic people from Xavante ethnic group in Mato Grosso - Brazil. The sample consisted in 50 indigenous people, characterized by gender, age, educational level, income, marital status and number of children. It was made the anamnesis and a clinical evaluation, asking for precondition on DM and/or SAH, and the use or not of traditional medicine. It was used a digital wrist blood pressure monitor and a capillary blood glucose meter. It was performed a chi-square test, a Pearson test, a Kruskal Wallis test, a Student's t test, a Pearson's correlation coefficient and an ANOVA tests. One third of the participants received up to one minimum wage; 22% of them were compatible with pre-diabetes and 26% were diabetic; the average the SAH was 122.5 (± 14.5) by 79.8 (± 9.4) mmHg. It was found a significant relationship between income, marital status, age and presence of children, with clinical data and multifactorial risk aspects.Descriptors: Indigenous, Systemic Arterial Hypertension, Diabetes Mellitus. Rastreando enfermedades crónicas en la comunidad indígenaResumen: La hipertensión arterial sistémica (HAS), diabetes mellitus (DM), sedentarismo y síndrome metabólico afectan la salud indígena. Este estudio tiene como objetivo identificar hipertensos y diabéticos de la etnia Xavante, Mato Grosso. La muestra fue compuesta por 50 indígenas, caracterizados por sexo, edad, escolaridad, renta, estado civil y número de hijos. Se hizo la anamnesis y la evaluación clínica, con antecedentes de DM y/o HAS y el uso de medicaciones tradicionales. Se usaron tensiómetro digital de pulso y glucómetro capilar. Se hizo el análisis con las pruebas Chi-cuadrado, Pearson, Kruskal Wallis, t de Student, coeficiente de correlación de Pearson y ANOVA. Un tercio de los participantes recibían hasta un salario mínimo; 22% eran compatibles con prediabetes y 26% diabéticos; la HAS estuvo en una media de 122,5 (±14,5) por 79,8 (±9,4) mmHg. Hubo relación significativa entre renta, estado civil, edad y presencia de hijos, con los datos clínicos y los aspectos multifactoriales de riesgo.Descriptores: Indígena, Hipertensión Arterial, Diabetes Mellitus.



2018 ◽  
Vol 12 (2) ◽  
pp. 57-63
Author(s):  
Simona Di Francesco ◽  
Marika Caruso ◽  
Iole Robuffo ◽  
Andrea Militello ◽  
Elena Toniato

Background: The impact of metabolic syndrome on female sexual dysfunction received modest consideration in clinical practice. The aim of the research was to analyze the international literature to determine the relationship between the metabolic syndrome, its components and female sexual disorders. Methods: We identified relevant full-length papers by electronic databases as Index Medicus/Medline, Scopus, Life Science Journals, from 2005 to the present. Studies were searched using the following as search query: metabolic syndrome, female sexual dysfunction, obesity, systemic arterial hypertension, diabetes mellitus, dyslipidemia. Results: Women with metabolic syndrome showed higher prevalence of sexual inactivity and low sexual desire, orgasm and satisfaction respect to women without metabolic syndrome. Particularly metabolic components as diabetes mellitus, dy-slipidemia, systemic arterial hypertension were strongly associated with lower sexual desire, activity and Female Sexual Function Index total score. In contrast, other studies showed no relationship. Conclusion: Our study showed that in the clinical evaluation of women with metabolic syndrome routine inquiring about female sexual dysfunction should be recommended to ameliorate sexual function and quality of life. However more prospective and longitudinal studies on the sexual effects of metabolic syndrome should also be suggested to know the factors related to women's sexuality better.



2018 ◽  
Vol 12 (4) ◽  
pp. 849
Author(s):  
Maria Evani Souza Borges ◽  
Jefferson De Sousa Melo ◽  
Luiza Chayanne Da Silva Soares ◽  
Adélia Dalva Da Silva Oliveira ◽  
Adriana Sávia De Souza Araújo ◽  
...  

RESUMOObjetivo: identificar os fatores de risco para a hipertensão arterial sistêmica e diabetes mellitus em vigilantes. Método: estudo quantitativo, descritivo, transversal, realizado com 23 vigilantes, por meio de um questionário analisado pelo software SPSS e apresentado em tabelas. Resultados: predominou os que praticam atividade física; não fumam; não consomem bebida alcóolica; consomem vegetais, frutas, legumes ou grãos; consomem frituras, salgados ou carnes gordas; têm antecedentes pessoais e familiares de hipertensão e diabetes, com maior ocorrência de hipertensão. A maioria obteve pressão arterial ótima e risco aumentado e muito aumentado para obesidade abdominal. Conclusão: apesar da atividade exercida ser considerada fator predisponente para a hipertensão arterial sistêmica e diabetes mellitus, os pesquisados demonstraram hábitos de vida saudáveis e níveis pressóricos dentro do padrão de normalidade. Descritores: Saúde Pública; Diabetes Mellitus; Hipertensão; Trabalho em Turnos; Fatores de Risco; Enfermagem.                                                                                                                    ABSTRACT Objective: to identify the risk factors for systemic arterial hypertension and diabetes mellitus in vigilantes. Method: quantitative, descriptive, cross - sectional study with 23 vigilantes, through a questionnaire analyzed by SPSS software and presented in tables. Results: predominantly those who practice physical activity; do not smoke; do not consume alcoholic beverage; consume vegetables, fruits, vegetables or grains; eat fried foods, salty foods or fatty meats; have a personal and family history of hypertension and diabetes, with a higher occurrence of hypertension. Most had optimal blood pressure and increased and greatly increased risk for abdominal obesity. Conclusion: although the activity was considered a predisposing factor for systemic arterial hypertension and diabetes mellitus, the subjects showed healthy habits and blood pressure levels within the normal range. Descritores: Public Health; Diabetes Mellitus; Hypertension; Shift Work; Risk Factors; Nursing. RESUMEN Objetivo: identificar los factores de riesgo para la hipertensión arterial sistémica y la diabetes mellitus en vigilantes. Método: estudio cuantitativo, descriptivo, transversal, realizado con 23 vigilantes, por medio de un cuestionario analizados por el software SPSS y presentados en tablas. Resultados: predominó los que practican actividad física; no fuman; no consumen bebida alcohólica; consumen vegetales, frutas, legumbres o granos; consumen frituras, salados o carnes gordas; tiene antecedentes personales y familiares de hipertensión y diabetes, con mayor ocurrencia de hipertensión. La mayoría obtuvo una presión arterial óptima y un riesgo aumentado y muy aumentado para la obesidad abdominal.  Conclusión: a pesar de la actividad ejercida como factor predisponente para la hipertensión arterial sistémica y diabetes mellitus, los encuestados demostraron hábitos de vida saludables y niveles de presión dentro del patrón de normalidad. Descritores: Salud Pública; Diabetes Mellitus; Hipertensión; Trabajo en Turnos; Factores de Riesgo; Enfermería.



2005 ◽  
Vol 36 (5) ◽  
pp. 374-380 ◽  
Author(s):  
Ingrid U Scott ◽  
Harry W Flynn Jr ◽  
Luma Al-Attar ◽  
Gail L Ganser ◽  
Antonio V Aragon ◽  
...  


Author(s):  
Leonardo Hesley Ferraz Durans ◽  
Lisa Steffany Pinheiro Pereira ◽  
Thamyres da Cruz Miranda ◽  
Fabrício Silva Sousa ◽  
Geylene Albuquerque Ribeiro ◽  
...  


Author(s):  
Shashank Mishra ◽  
Himanshu Kumar Shukla ◽  
Rajiv Singh ◽  
Vivek Pandey ◽  
Shubham Sagar ◽  
...  

The sudden increase in COVID-19 patients is a major shock to our global health care systems. With limited availability of test kits, it is not possible for all patients with respiratory infections to be tested using RT-PCR. Testing also takes a long time, with limited sensitivity. The detection of COVID-19 infections on Chest X-Ray can help isolate patients at high risk while awaiting test results. X-Ray machines are already available in many health care systems, and with many modern X-Ray systems already installed on the computer, there is no travel time involved in the samples. In this work we propose the use of chest X-Ray to prioritize the selection of patients for further RT-PCR testing. This can be useful in a hospital setting where current systems have difficulty deciding whether to keep the patient in the ward with other patients or isolate them from COVID-19 areas. It may also be helpful in identifying patients with high risk of COVID with false positive RT-PCR that will require repeated testing. In addition, we recommend the use of modern AI techniques to detect COVID-19 patients who use X-Ray imaging in an automated manner, especially in areas where radiologists are not available, and help make the proposed diagnostic technology easier. Introducing the CovidAID: COVID-19 AI Detector, a model based on a deep neural network of screening patients for proper diagnosis. In a publicly available covid-chest x-ray-dataset [2], our model provides 90.5% accuracy with 100% sensitivity (remember) to COVID-19 infection. We are greatly improving the results of Covid-Net [10] on the same database.



Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7851
Author(s):  
Koena L. Moabelo ◽  
Darius R. Martin ◽  
Adewale O. Fadaka ◽  
Nicole R. S. Sibuyi ◽  
Mervin Meyer ◽  
...  

The coronavirus disease 2019 (COVID-19) pandemic has gained worldwide attention and has prompted the development of innovative diagnostics, therapeutics, and vaccines to mitigate the pandemic. Diagnostic methods based on reverse transcriptase-polymerase chain reaction (RT-PCR) technology are the gold standard in the fight against COVID-19. However, this test might not be easily accessible in low-resource settings for the early detection and diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The lack of access to well-equipped clinical laboratories, requirement for the high level of technical competence, and the cost of the RT-PCR test are the major limitations. Moreover, RT-PCR is unsuitable for application at the point-of-care testing (PoCT) as it is time-consuming and lab-based. Due to emerging mutations of the virus and the burden it has placed on the health care systems, there is a growing urgency to develop sensitive, selective, and rapid diagnostic devices for COVID-19. Nanotechnology has emerged as a versatile technology in the production of reliable diagnostic tools for various diseases and offers new opportunities for the development of COVID-19 diagnostic systems. This review summarizes some of the nano-enabled diagnostic systems that were explored for the detection of SARS-CoV-2. It highlights how the unique physicochemical properties of nanoparticles were exploited in the development of novel colorimetric assays and biosensors for COVID-19 at the PoCT. The potential to improve the efficiency of the current assays, as well as the challenges associated with the development of these innovative diagnostic tools, are also discussed.





2020 ◽  
Vol 45 ◽  
pp. e020015
Author(s):  
Soraya Andrea Delefrate Muradas ◽  
Amanda Sayuri Nakamura ◽  
Jader Dornelas Neto ◽  
Taisa Valques Lorencete ◽  
Daniel Vicentini de Oliveira ◽  
...  

Introduction: Coronary artery disease is the largest cause of mortality in the world. The main risk factors for its development include systemic arterial hypertension and type 2 diabetes mellitus. Objective: To search for predictors of the development of plaques and obstructions in coronary arteries and to determine whether the exercise test is a reliable pretest for coronary angiotomography. Methods: 883 computed tomography reports of coronaries were analyzed. Sociodemographic information, health conditions and results of the exercise test from patients were collected, along with calcium score, percentile and number of arterial segments with significant obstruction. The data were analyzed using descriptive and inferential statistics. Significance was considered for p<0.05. Results: It observed that the statistically significant predictors to the calcium score were male, being over 60 years old, having type 2 diabetes mellitus and systemic arterial hypertension. There was no relationship with high BMI and coronary obstruction. Regarding the exercise test, it was possible to observe that the majority of individuals who were positive in the exercise test, did not have a positive calcium score or significant coronary obstructions. Conclusion: The predictors for the development of coronary plaques and obstructions were male, aged ≥60 years, having type 2 diabetes mellitus and systemic arterial hypertension.



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