scholarly journals Extra-intestinal salmonellosis in a tertiary care center in South India

2014 ◽  
Vol 8 (07) ◽  
pp. 831-837 ◽  
Author(s):  
Sukanya Sudhaharan ◽  
Kanne Padmaja ◽  
Rachana Solanki ◽  
Vemu Lakshmi ◽  
Pamidi Umabala ◽  
...  

Introduction: The present study is a retrospective analysis of a total of 36 cases of bacteriologically proven extra-intestinal salmonellosis, managed at Nizam’s Institute of Medical Sciences, between 1987 and 2012 (25 years). The extra-intestinal sites involved were the skin, cerebrum, spleen, ovary, synovium, and the skeletal muscle. Methodology: The extra-intestinal specimens were first processed using standard methods. Colonies suspected as Salmonella were identified by standard laboratory methods, initially by manual biochemical reactions and later by the API system (bioMerieux, Marcy l’Etoile- France) and the Vitek-2 system (bioMerieux). All the Salmonella isolates were sent to Central Research Institute, Kasauli, for serotyping. Results: The predominant serotype isolated was Salmonella Typhi (S. Typhi) in 27 (75%) patients, followed by Salmonella Senftenberg (S. Senftenberg) in 5 (14%), Salmonella Paratyphi A (S. Paratyphi A) in 3 (8%), and Salmonella Typhimurium (S. Typhimurium) in 1 (3%). There was an increasing resistance to ampicillin, chloramphenicol, cephalosporins (third generation), and quinolones over the 25 years. Conclusions: The diagnosis of extra-intestinal salmonellosis requires a high degree of clinical suspicion and should be included in the differential diagnosis in patients with deep-seated abscesses.

2016 ◽  
Vol 7 (3) ◽  
pp. 54-57
Author(s):  
Animesh Panda ◽  
Shiv Kumar Chandrakar ◽  
Smita Bawankar ◽  
Dhruba Hari Chandi

Background : Before starting to discuss about Diarrhoea, we have to remember diarrhoea is one of the main causes of morbidity and mortality in children. Aims and Objectives : The aim of this study was to determine the prevalence of intestinal parasitic and bacterial infections as cause of childhood diarrhoea. Materials and Methods : During the study period, a total of 116 stool samples were collected and processed. Examined grossly and microscopically for presence of ova/cyst. They were also cultured on MacConkey agar and E. coli isolated were identified by standard biochemical tests.Results : Out of 116 stools samples, Entamoeba histolytica (63.33%) and Giardia lamblia (23.33%) were more common parasitic cause diarrhoea among children by either ova or cyst. E.coli (74.13%) was common bacterial cause of diarrhoea among children. E. coli isolated in pure culture and sent for sero typing to Central Research Institute (CRI), Kasauli. Maximum percent were found to be pathogenic Escherichia coli i.e. EPEC 22.5%. Conclusion :  According to the result, the most common cause of bacterial diarrhoea is E.coli. EPEC were more prevalent followed by EHEC. Thus, macroscopic and microscopic stool examinations as well as culture were important for finding out the course of diarrhoea in childhood.Asian Journal of Medical Sciences Vol. 7(3) 2016 54-57


2021 ◽  
pp. 8-10
Author(s):  
Gauri Thakare ◽  
Sonal Chavan ◽  
Sharmila Raut ◽  
Rajani Tore ◽  
Ravindra Khadse

PURPOSE: Comparative Study done for Vancomycin susceptibility in Methicillin Resistant Staphylococcus aureus (MRSA) in two methods Vitek-2 and E-strip test. MATERIAL AND METHOD: Vancomycin susceptibility testing was performed on these Methicillin Resistant Staphylococcus aureus (MRSA) isolates by two methods viz. Vitek 2 & E- strip Test. RESULT: A total of 10680 various specimens were received and processed in laboratory. 210 samples were S. aureus amongst which 76 were MRSAs. Pus was the predominant sample followed by endotracheal secretions, blood, and sputum. All the strains of MRSA found susceptible to vancomycin (MIC≤ 2µg/ ml) by both the methods. Maximum specimens by both the methods had MICs of 1.0 µg/ ml. CONCLUSION: In the present study results of Vitek and E-strip were almost comparable. In the advanced era of automation and computerized technology with manpower compromised labs, Vitek could be a better option for vancomycin MIC.


2018 ◽  
Vol 10 (04) ◽  
pp. 401-405 ◽  
Author(s):  
Sukanya Sudhaharan ◽  
Padmaja Kanne ◽  
Lakshmi Vemu ◽  
Aparna Bhaskara

ABSTRACT BACKGROUND: Infection with Salmonella has become an increasing problem worldwide. Recently, nontyphoid Salmonella (NTS) has become a global concern causing threat to the health of human. It causes gastrointestinal infection which may be self-limiting, but invasive infections may be fatal, requiring appropriate therapy. This study was done to analyze the spectrum of NTS infections causing extraintestinal infections and its susceptibility pattern from a tertiary care center in India. MATERIALS AND METHODS: The medical records of 27 patients whose cultures were positive for NTS between the years 2013–2016 were included in this retrospective study. The relevant demographic, clinical, and laboratory data were analyzed. RESULTS: Among the 27 patients, predominant patients were in the age group of 20–30 years. The male to female ratio is 1.7:1. Salmonella typhimurium was the predominant NTS isolated among 15/27 (55.5%), followed by Salmonella enteritidis 4/27 (14.8%). 18/27 (66.6%) of NTS were isolated from blood. Nalidixic acid was sensitive in 2/15 of S. typhimurium, 2/4 of S. enteritidis and 1/3 of Salmonella weltevreden, while others are nalidixic acid-resistant implying resistance to quinolones. They were sensitive to other antibiotics reported. CONCLUSION: This study highlights the spectrum of NTS causing extraintestinal infections which is an emerging infection occurring mostly in immunosuppressed individuals. There should be a high degree of clinical suspicion which would help in the early diagnosis and management of patients.


2019 ◽  
Vol 21 (2) ◽  
pp. 252-255
Author(s):  
A K Iordanishvili

Presents information from the life of a maxillofacial surgeon and dentist, one of the patriarchs of domestic dentistry, a veteran of the Great Patriotic War, academician of the Academy of Medical Sciences of the Union of Soviet Socialist Republics, doctor of medical sciences, professor, colonel of medical service Anatoly Ivanovich Rybakov, known in our country and abroad. , who was the first director of the Central Research Institute of Dentistry. The data on the formation of A.I. Rybakov as a military doctor and dentist, his combat path during the Great Patriotic War. Turning to the life and professional and social activities of Anatoly Ivanovich, one can find not only interesting scientific facts from the history of dentistry and maxillofacial surgery, but also analogies with modernity, answers to many clinical problems of the specialty and medicine of today. The main directions of his scientific activity, which touched questions of almost all sections of dentistry and maxillofacial surgery, are noted. A.I. Rybakov was one of the creators of the working concept of the pathogenesis of dental caries and periodontal diseases, the author of the first recorded discovery in dentistry on the phenomenon of the production of intestinal antigen by the oral mucosa of mammals, the founder of the study of the epidemiology of dental diseases in Russia and the Republics of the Soviet Socialist Republics. It is noted that he was a refined connoisseur of the history of national ballet, a true professional and an authority in this field of art. Anatoly Ivanovich, being one of the founders of domestic dentistry, as well as the school of dentists and maxillofacial surgeons, is rightfully recognized as one of the patriarchs of domestic dentistry.


2018 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Rajesh Poudel ◽  
Santosh Shah ◽  
Kailash Chandra ◽  
Saroj Pradhan ◽  
Pravin Joshi

Introduction: Despite advances in surgical technique, antimicrobial therapy and perioperative care morbidity and mortality in perforated peritonitis is still high.   Aim of this study was to highlight the clinical presentation, intra operative findings and postoperative complications and mortality among patient who has undergone emergency surgery for perforated peritonitis in tertiary care center in western Nepal.Materials and Methods: This was a retrospective descriptive study carried out in Universal College of Medical Sciences, Bhairawha, Nepal. All patients who underwent emergency exploratory laparotomy for perforated peritonitis in one year period (from April 2014 to March 2015) were included in the study.Results: Total 90 cases met inclusion criteria and were analyzed. Most common presenting symptom was pain abdomen. Pneumoperitoneum was seen in 86 (95.6%) patients. Most common site of perforation was prepyloric perforation followed by duodenum. Most common cause of perforation was Acid peptic disease. Most common surgical procedure performed was Omentopexy. There were total of 11 (12.2%)mortality.Conclusion: The spectrum of perforation peritonitis in our study differs from western countries whereas it is similar to that of other research from Indian subcontinent. Majority of perforations are noticed in the duodenum and stomach due to acid-peptic disease and small bowel typhoid followed by trauma. Overall mortality was seen in 12.2%.Journal of Universal College of Medical ScienceVol. 6, No. 1, 2018, Page: 11-13


2021 ◽  
Vol 33 (2) ◽  
pp. 282-287
Author(s):  
Arshad Ayub ◽  
Geetika Singh ◽  
Shamshad Ahmad ◽  
Saket Shekhar ◽  
Bhojraj Palariya ◽  
...  

Background: The services provided in an ICTC help in awareness about HIV and help the clients to undergo HIV test in a comfortable and confidential environment. Periodical evaluation of counseling, testing, and referral services is mandatory to find out any existing deficits and barriers of all functions of ICTCs. Objectives: To study the socio-demographic profile of ICTC attendees and to find out sero-positivity of these clients. Methods: The present study was carried out among ICTC attendees in the ICTC unit, at All India Institute of Medical Sciences of Patna district. A retrospective collection of data from available records of all clients who attended ICTC of our hospital between January 2019 and December 2019 was carried out after approval from institutional research and ethics committee. Results: A total of 28876 clients were tested during January-December 2019 and among them all (100%) of tests were provider initiated. Out of the total attendees, 223 (0.77%) were found to be positive. It was also observed that the number of clients attending the ICTC has increased every month. Conclusion: It shows a high illiteracy and high spouse positive rate among the reactive cases. The young age group was found to be affected more and it definitely raises a cocern.


2021 ◽  
Author(s):  
Ashwin Parchani ◽  
K Vidhya ◽  
Prasan Kumar Panda ◽  
Vikram Singh Rawat ◽  
Yogesh Arvind Bahurupi ◽  
...  

Background Disease pandemics are known to cause psychological distress. The ensuing mental health issues are not only restricted to the patients and their relatives/friends but affect the healthcare workers (HCWs) as well. Our study aims to assess these psychological trends during the COVID-19 pandemic between the two most affected population groups, that is, patients and frontline healthcare workers. Methods A survey questionnaire including scales to assess fear, anxiety, stress, depression - PSS 10, and DASS 21 was distributed and sent to all COVID-19 suspected/confirmed individuals and healthcare workers at a tertiary care center along with a second visit after 14 days of answering the first questionnaire and this continued as follow up. Data were analyzed with the SPSS Version 23 using various tests of significance. Results In the community, COVID-19 patients in the age group 41-50 with respiratory tract symptoms and those who were home isolated/quarantined experienced a greater tendency of mental health problems. Healthcare workers posted in COVID-19 designated areas of the hospital displayed higher levels of stress, anxiety, and depression. Conclusion The high degree of uncertainty associated with novel pathogens has a profound effect on the psychological state of suspected/confirmed cases as well as healthcare workers. Within the community, individuals suspected of having COVID-19 display a significant mental health burden, while HCWs also experience an unprecedented amount of stress during such enduring situations.


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