scholarly journals Sunscreen Activities of Bark Artocarpus heterophyllus against Ultraviolet Ray (Sun Protection Factor) in Lotion Formula

2020 ◽  
Vol 8 (A) ◽  
pp. 461-467
Author(s):  
Bastian Arifin ◽  
Rosnani Nasution ◽  
Savila Savila ◽  
Rika Ramadani ◽  
Hira Helwati ◽  
...  

Sunscreen lotion is used to prevent the skin from ultraviolet radiation, which can cause various diseases, such as acne, burning, redness, swelling, wrinkling, and skin cancer. Natural sunscreen lotions contain chemical compounds that have relatively long conjugated double bonds or the presence of hydroxyl groups. The result of the maceration of Artocarpus heterophyllus bark produced ethanol and methanol extracts, based on gas chromatography-mass spectrometry characterization, both extracts contained straight and cyclic chain compounds which had conjugated double bonds. The number of double-bonded compounds in ethanol extract is more than in methanol extract. Sun protection factor (SPF) value of ethanol extract lotion formula is greater than SPF value of methanol extract lotion formula, the SPF value ethanol extract lotion formula at concentration 2; 2.5; 5; 7.5; and 12% were consecutive: 29.801 ± 0.224; 32.797 ± 0.161; 33.808 ± 0.165; 34.580 ± 0.295; and 35.015 ± 0.169, (SPF value of negative control: 0.435 ± 0.2839 and positive control, 31 ± 0.0284). SPF value of methanol extract lotion formula for concentration 2; 2.5; 5; 7.5; and 12% was 14.407 ± 0.010; 26.549 ± 0.476; 30.274 ± 0.208; 32.031 ± 0.302; and 31.942 ± 0.324. Each extract SPF value is higher than the SPF value of the lotion formula. The result of testing the physical properties of the lotion formula shows that the lotion type is o/w, the lotion viscosity ranges from 2450 cP to 4780.0 cP meet Standar Nasional Indonesia (SNI) standards. The pH test results ranged from 6.020 to 7.845 meets SNI. The spreading power of the lotion ranges from 4.70 to 6.75 cm. The adhesive strength of the lotion ranges from 16 to 41 s.

Author(s):  
Pahol Sansomchai ◽  
◽  
Kanlaya Jumpatong ◽  
Chaipat Lapinee ◽  
Kanchana Utchariyajit ◽  
...  

The ultimate aim of this study was to evaluate antioxidant activities using DPPH and ABTS assay and antioxidant substances of Melientha suavis Pierre (Melientha) extracts with ethanol (EtOH) and subsequent partition with hexane, dichloromethane (CH2Cl2), ethyl acetate (EtOAc) and distilled water (W). The Melientha extract was assessed the sunscreen activities by sun protection factor which was compared with octyldimethyl PABA. Additionally, the stability test of Melientha extracts added in the cosmetic base-formula was investigated. The sun protection substances of Melientha extracts were determined by GC-MS analysis. Among the extract and fractions, the ethanolic extract showed the highest activities. The IC50 of Melientha extract to free radical scavenging determined by DPPH assay and ABTS assay were 53.20 ± 7.37 μg/ml and 64.17 ± 5.76 μg/ml, respectively. The total phenolic compound of ethanol extract was 149.87 ± 2.72 mg GE/g of ext and total flavonoid content was 51.60 ± 4.12 mg CE/g of ext. The sun protection factor (SPF) of ethanol extract was 26.61 ± 0.10. Cinamate and its derivative which were claim as sunscreen substance was found by GC-MS analysis of Melientha ethanol extract.


2020 ◽  
Vol 16 ◽  
Author(s):  
Rima Goudjil ◽  
Abdelkader Mekhaldi ◽  
Houari Benamar ◽  
Chawki Bensouici ◽  
Mohamed Amine Kahoul

Background:: Lawsonia inermis Linn (Lythraceae), commonly known as "Henna" is a medicinal plant widely used as a folk remedy and for its cosmetic properties. Objective:: The objective of this present work was to evaluate biological activities and to quantify phenolics in extracts. Methods:: The extracts were obtained from seeds of L. inermis by increasing the polarity of the solvent. The content of total phenolics, flavonoids, flavonols and tannins was determined using colorimetric methods. Also, to evaluate the antioxidant activity, six different assays, DPPH, ABTS, superoxide radical scavenging, inhibition of β-carotene bleaching, ferric reducing antioxidant power and phenanthroline assays were used. Enzyme inhibition activity was evaluated by acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition assays. Furthermore, photoprotective activity was determined by measuring sun protection factor. Results:: The extraction efficiency of phenolics, as well as the biological activities of plant extracts, were affected by solvent polarity. The highest content of phenolics was determined in methanol extract (786.54 ± 0.00 mg GAEg-1 DW), followed by the aqueous and ethyl acetate extracts (526.48 ± 0.40 and 331.25 ± 0.00 GAEg-1 DW, respectively). The above extracts also exhibited the highest antioxidant activity, while low polar extracts were characterized with the lowest content of phenolics, as well as the lowest antioxidant capacity. The highest enzyme inhibition activities were found in ethyl acetate extract. Moreover, the methanol extract showed the best photoprotective activity with sun protection factor of 43.05 ± 0.37. Conclusion:: These findings suggest a possible use of Henna seeds as a potential source of bioactive molecules with antioxidant, enzyme inhibition and skin protection properties.


Jurnal MIPA ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 46
Author(s):  
Irmawati Anggriani ◽  
Max R.J. Runtuwenen ◽  
Vanda S. Kamu

Penelitian ini bertujuan untuk menguji aktivitas perlindungan tabir surya dari ekstrak etanol kulit buah, kulit biji dan biji pinang yaki secara in vitro. Tahap pendahuluan penelitian ini yaitu menguji nilai SPF (Sun Protection Factor) yang dilakukan secara invitro dengan menggunakan metode spektrofotometri UV-Vis. Serbuk kulit buah, kulit biji dan biji dimeserasi dengan pelarut etanol kemudian dipekatkan dengan rotary evaporator sehingga menghasilkan ekstrak pekat. Ekstrak etanol kulit buah, kulit biji dan biji pinang yaki memiliki nilai SPF yang berbeda yaitu 12,05 , 3,45 , dan 1,00. Dari nilai SPF ketiga sampel tersebut, kulit buah yang memiliki nilai SPF tertinggi dan termasuk dalam kategori Proteksi Maksimum sehingga kulit buah pinang yaki dapat dilakukan uji lanjut tentang aktivitas perlindungan tabir surya secara in vivo.The purpose of this study were to test the sunscreen protection activity of ethanol extract of the skin of Pinang Yaki fruit, shell skin and seed by using in vitro method. The preliminary stage of this research was to test the value of SPF (Sun Protection Factor) by invitro using UV-Vis spectrophotometry method. Skin of Pinang Yaki Fruit, shell skin and seed were maceration with ethanol then concentrated with a rotary evaporator to produce a concentrated extract. Skin of Pinang fruit, shell skin and seed have different SPF values of 12.05, 3.45, and 1.00. From the SPF values of the three samples, the skin of the fruit has the highest SPF value and is included in the Maximum Protection category so that the skin of Pinang Yaki fruit could be tested futher for  sunscreen protection activity by in vivo method.


2019 ◽  
Vol 4 (2) ◽  
pp. 26-31
Author(s):  
Rabiatul Adawiyah

The sunscreens or Sun Protecting Agent is the materials protecting the skin from the exposure to ultraviolet (UV) rays. Amount of Sun Protection Factor shows how many times the subject skin protection can be multiplied under the sun rays without erythema occurs. Kalakai contains some bio-active substance like phenol, flavonoid, alkaloid and terpenoid family which are proven as a very effective antioxidant. The purpose of this research was to determine the concentration of ethanol extract of kalakai root which has the potential as a sunscreen based on the Sun Protection Factor (SPF) parameter. Determination of SPF amount was carried out in vitro by UV-VIS spectrophotometer at a concentration of 50 ppm, 100 ppm, 150 ppm, 200 ppm, 250 ppm, 300 ppm, and 350 ppm with a wavelength of 290-320 nm. The result showed that kalakai root ethanol extract indicated potential as a sunscreen at a concentration of 300 ppm and 350 ppm obtained SPF values respectively 11 and 14 classified as sunscreens with extreme ability levels.


2021 ◽  
Vol 6 (2) ◽  
pp. 252-261
Author(s):  
Muhammad Ikhwan Rizki ◽  
◽  
Samsul Hadi ◽  
Lutfi Chabib

UV rays cause skin damage such as loss of skin elasticity, wrinkles, sagging, and skin cancer. South Kalimantan is a wetland area with more than 4,000 species of medicinal plants. Mundar (Garcinia forbesii) is one of the plants in South Kalimantan. Mundar pericarp is empirically used for cosmetics which is believed to protect the skin from ultraviolet rays. The purpose of the study was to determine the sunscreen potency of the extract and fraction from pericarp of mundar (Garcinia forbesii) based on the Sun Protection Factor (SPF) parameter. The research started from material drying, making simplicia powder, extraction, and fractions. The extracts and fractions were measured for SPF values ??using a UV-Vis Spectrophotometer. The results showed that the ethanol extract and ethyl acetate fraction had weak protection, while the n-hexane fraction had extreme protective power with SPF values ??in the range of 6.51 – 30.00


Author(s):  
Priyanka S ◽  
Mary Shobha Rani Inala ◽  
Nandini Hs ◽  
Kutty Avm ◽  
Kiranmayee P

Objective: The aim of the present work is to investigate the presence of ultraviolet (UV) light absorption capacity of the selected plant extracts. Chemical-based sunscreens provide protection against the sun’s rays, in particular, UV radiation. Sometimes, exposure to these chemicals leads to allergies to the skin. The best way to protect skin from chemical and photoallergies is to use plant-based creams and lotions.Methods: Methanol and water extracts of Datura metel leaves and flowers; Loranthus leaves and flowers; and Eucalyptus leaves were prepared and checked their UV absorption ability from 200 nm to 450 nm. Different concentrations of the same extracts were tested for their sun protection factor (SPF) using Mansur formula from 290 to 320 nm. All the extracts showed absorption at UV range.Result: The calculated values of SPF were fallen in the range of 0.4–23.5. Among the three plants used in this study, methanol extract of Eucalyptus showed highest UV absorption than the other two plants. In vitro studies of a few phenolics from various plants have been found to be mutagenic. This might be the result of pro-oxidant than antioxidant action of these compounds. Keeping in view of human use as SPFs, it is indispensable to investigate the toxic effects of the extracts.Conclusion: The preliminary findings of this study reveal that the methanol extract of Eucalyptus has a high sun protection effect. This extract can be used as additives in other sunscreen formulations to enhance their SPF.


2021 ◽  
Vol 18 (01) ◽  
pp. 24
Author(s):  
Weni Puspita ◽  
Heny Puspasari

ABSTRACT Premna serratifolia L. leaves contain flavonoids, saponins, polyphenols, and terpenoids, potentially act as sunscreens. The purpose of this study was to determine the flavonoid content and SPF (Sun Protection Factor) ethanol extract of Premna serratifolia L. leaves from Melawi Regency, West Kalimantan Province using UV-Vis spectrophotometer. The Premna serratifolia L. leaves were extracted by maceration using 70% ethanol solvent, then the filtrate obtained was concentrated with a rotary vacuum evaporator to obtain a thick extract. The extract was determined for its flavonoid content using UV-Vis spectrophotometer at a wavelength of 439 nm, and the SPF value was determined at a concentration of 25, 50, 75, and 100 ppm with a UV-Vis spectrophotometer at a wavelength of 290-320 nm. The SPF value was calculated and analyzed descriptively using the Mansur method. The result showed that the average flavonoid content of ethanol extract of Premna serratifolia L. leaves was 3.70±0.02% calculated as quercetin. The SPF EEDB values obtained from variations in concentrations of 25, 50, 75, and 100 ppm respectively were 19.95±0.02; 30.08±0.01; 34.58±0.14; and 38.28 ± 0.12, where the SPF value is included in the ultra protection category. Key words: Premna serratifolia L. leaves, flavonoid content, SPF, UV-Vis Spectrophotometer


Sign in / Sign up

Export Citation Format

Share Document