Aspergillus nomius, an important aflatoxin producer in Brazil nuts?

2008 ◽  
Vol 1 (2) ◽  
pp. 123-126 ◽  
Author(s):  
M. Olsen ◽  
P. Johnsson ◽  
T. Möller ◽  
R. Paladino ◽  
M. Lindblad
Keyword(s):  
Aspergillus Flavus ◽  
Prevention And Control ◽  
Influence Strategies ◽  
Fungal Strains ◽  
Brazil Nuts ◽  
Aspergillus Nomius ◽  
Aflatoxin B ◽  
And Control ◽  
The Relationship

The relationship between aflatoxin B1 and G1 was examined in samples from 199 aflatoxin contaminated lots of inshell Brazil nuts imported to Europe. In most of the samples, the relationship between B1 and G1 were approximately 50/50 indicating that the major responsible aflatoxin producing fungi cannot be Aspergillus flavus, which produces solely B aflatoxins. Fungal strains were isolated from two batches of Brazil nuts and isolates of both A. nomius and A. flavus could be identified. The A. nomius isolates were good producers of both B and G aflatoxins, while the A. flavus strains only produced B aflatoxins. In conclusion, this study suggests that A. nomius is an important producer of aflatoxins in Brazil nuts and that its occurrence, and possibly other B and G aflatoxin producers, should be further examined since this may influence strategies for prevention and control of aflatoxins in Brazil nuts.

scholarly journals The Impacts of Regional Regulatory Policies on the Prevention and Control of Chronic Diseases in China: A Mediation Analysis

Healthcare ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1058
Author(s):  
Huihui Huangfu ◽  
Qinwen Yu ◽  
Peiwu Shi ◽  
Qunhong Shen ◽  
Zhaoyang Zhang ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Community Service ◽  
Mediation Analysis ◽  
Prevention And Control ◽  
Negative Binomial ◽  
Mediating Effect ◽  
Negative Binomial Regression Model ◽  
Regulatory Policies ◽  
And Control ◽  
The Relationship

Regional regulatory policies (RPs) are a major factor in the prevention and control of chronic diseases (PCCDs) through the implementation of various measures. This study aimed to explore the impacts of RPs on PCCDs, with a focus on the mediating roles of community service. The soundness of the regulatory mechanism (SORM) was used to measure the soundness of RPs based on 1095 policy documents (updated as of 2015). Coverage provided by community service institutions (CSIs) and community health centres (CHCs) was used to represent community service coverage derived from the China Statistical Yearbook (2015), while the number of chronic diseases (NCDs) was used to measure the effects of PCCDs based on data taken from the 2015 China Health and Retirement Longitudinal Study survey. To assess the relationship between SORM, NCDs and community service, a negative binomial regression model and mediation analysis with bootstrapping were conducted. Results revealed that there was a negative correlation between SORM and NCDs. CSIs had a major effect on the relationship between RPs and PCCDs, while CHCs had a partial mediating effect. RPs can effectively prevent and control chronic diseases. Increased effort should also be aimed at strengthening the roles of CSIs and CHCs.

COVID-19, infection prevention and control within acute inpatient mental health facilities: a new challenge requiring a new approach

2020 ◽  
Vol 16 (2) ◽  
pp. 69-74
Author(s):  
Lisa McLean ◽  
Louise Forrester
Keyword(s):  
Mental Health ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Mental Health Problems ◽  
Social Contact ◽  
Infection Prevention And Control ◽  
New Paradigm ◽  
Mental Health Settings ◽  
And Control ◽  
The Relationship

Mental Health inpatient units have a primary purpose of treating mental health problems, managing disturbance and promoting social contact and support networks. These factors can conflict with optimal infection prevention and control (IPC) measures.<br/> This commentary describes an IPC perspective of the challenges in managing the effects of the COVID-19 pandemic that are specific to acute mental health settings. It points out the main areas for IPC and mental health practice development.<br/> The need for a new paradigm in the relationship between IPC and mental health specialists is identified. Recent collaboration between mental health and IPC specialists in evaluating personal protective equipment (PPE) for use in restraint is outlined.

Study on the Key Environmental Factors Aspergillus flavus Growth and Aflatoxin Production

2014 ◽  
Vol 668-669 ◽  
pp. 1550-1553 ◽  
Author(s):  
Chu Shu Zhang ◽  
Qin Zhao ◽  
Jian Xiong Feng ◽  
Jie Sun ◽  
Li Na Yu ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Aspergillus Flavus ◽  
Prevention And Control ◽  
Aflatoxin Production ◽  
Aflatoxin Contamination ◽  
Key Factors ◽  
Culture Time ◽  
Burman Design ◽  
And Control ◽  
Plackett Burman Design

Single factor and Plackett-Burman design were used to determine the key environmental factors for Aspergillus flavus growth and aflatoxin production. The results showed that the key factors were culture time, moisture content. So Controling of moisture was crucial for Aflatoxin contamination prevention and control.

Growth of aflatoxigenic moulds and aflatoxin formation in Brazil nuts

2008 ◽  
Vol 1 (2) ◽  
pp. 127-137 ◽  
Author(s):  
P. Johnsson ◽  
M. Lindblad ◽  
A. Thim ◽  
N. Jonsson ◽  
E. Vargas ◽  
...  
Keyword(s):  
Relative Humidity ◽  
Field Data ◽  
Aflatoxin Production ◽  
Processing Plant ◽  
Production Chain ◽  
Brazil Nuts ◽  
Field Samples ◽  
Aspergillus Nomius ◽  
The Relationship ◽  
And Storage

The present study aimed at gaining more knowledge of the growth of aflatoxigenic moulds and aflatoxin production in Brazil nuts in relation to humidity conditions and storage time. For this purpose, the growth of aflatoxigenic moulds and the increase in aflatoxin levels in Brazil nuts was studied in the laboratory at temperature and humidity conditions that are relevant for the Amazon region. Fresh unprocessed Brazil nuts in shell were inoculated with an aflatoxin producing strain of Aspergillus nomius previously isolated from Brazil nuts. The nuts were stored at 27 °C in combination with 97, 90 or 80% surrounding relative humidity in a respirometer for up to 3 months. The General Linear Model (GLM) was used for evaluation of the effect of water activity and time on aflatoxigenic mould levels and on aflatoxin levels, as well as the relationship between mould and aflatoxin levels. During storage at the highest relative humidity (97%) aflatoxin formation occurred rapidly, whereas storage at 90% relative humidity resulted in slower aflatoxin formation. At the lowest relative humidity (80%), aflatoxin formation occurred sporadically during storage. The increase in mould and aflatoxin levels along the production chain is also described, using field data collected in the state of Para, Brazil. The growth of aflatoxigenic moulds and aflatoxin formation increased rapidly between 40-90 days following collection of the nuts, before the nuts reached the final drying stage at the processing plant. In addition, a logistic regression model predicting the probability that the European legislative limit of 4 µg/kg for aflatoxins in nuts will be exceeded in relation to colony counts of either one selected aflatoxigenic mould strain (laboratory experiments) or of a mixture of aflatoxigenic strains (field data) was developed. The probability that total aflatoxin levels will exceed the European legislative limit of 4 µg/kg increased rapidly from approx. 30% to above 80% for both experimental and field samples at mould levels between 2 and 3 log cfu/g.

scholarly journals The Influence of Potential Infection on the Relationship between Temperature and Confirmed Cases of COVID-19 in China

2021 ◽  
Vol 13 (15) ◽  
pp. 8504
Author(s):  
Weiran Lin ◽  
Qiuqin He
Keyword(s):  
Prevention And Control ◽  
Parametric Method ◽  
Floating Population ◽  
Gauss Kernel ◽  
Gamma Kernel ◽  
And Control ◽  
The Impact ◽  
The Relationship ◽  
Coronavirus Infections ◽  
Non Parametric

Considering the impact of the number of potential new coronavirus infections in each city, this paper explores the relationship between temperature and cumulative confirmed cases of COVID-19 in mainland China through the non-parametric method. In this paper, the floating population of each city in Wuhan is taken as a proxy variable for the number of potential new coronavirus infections. Firstly, to use the non-parametric method correctly, the symmetric Gauss kernel and asymmetric Gamma kernel are applied to estimate the density of cumulative confirmed cases of COVID-19 in China. The result confirms that the Gamma kernel provides a more reasonable density estimation of bounded data than the Gauss kernel. Then, through the non-parametric method based on the Gamma kernel estimation, this paper finds a positive relationship between Wuhan’s mobile population and cumulative confirmed cases, while the relationship between temperature and cumulative confirmed cases is inconclusive in China when the impact of the number of potential new coronavirus infections in each city is considered. Compared with the weather, the potentially infected population plays a more critical role in spreading the virus. Therefore, the role of prevention and control measures is more important than weather factors. Even in summer, we should also pay attention to the prevention and control of the epidemic.

scholarly journals Preliminary Basic Research on the Optimization of Oil Spill Prevention and Control Design Based on Numerical Simulation Technology for Zhoushan Ma’ao Port Area

2021 ◽  
Author(s):  
Junyan Dong ◽  
Zhibo Tang ◽  
Hanbao Chen
Keyword(s):  
Numerical Simulation ◽  
Oil Spill ◽  
Prevention And Control ◽  
Control Design ◽  
Basic Research ◽  
Port Area ◽  
And Control ◽  
The Relationship ◽  
Control Designs ◽  
Related Process

This paper gives a general overview of relevant studies about oil spill emergency control designs, analyzes and discusses the structure, function and main contents of these designs. Besides, the paper proposes an integrated and practical design of emergency response steps, with related process. Taking the port area of Ma’ao as a case, this paper comprehensively studies the relationship between the time of rescue vessels arriving at the oil spill location and the range of the port that can be covered by these vessels as well as the protection facilities required for the relevant shoreline.

scholarly journals aflN Is Involved in the Biosynthesis of Aflatoxin and Conidiation in Aspergillus flavus

Toxins ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 831
Author(s):  
Kunzhi Jia ◽  
Lijuan Yan ◽  
Yipu Jia ◽  
Shuting Xu ◽  
Zhaoqi Yan ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Aspergillus Flavus ◽  
Prevention And Control ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Hyphal Growth ◽  
Aflatoxin Production ◽  
Oxygen Species ◽  
Aflatoxin Biosynthesis ◽  
And Control

Aspergillus flavus poses a threat to society economy and public health due to aflatoxin production. aflN is a gene located in the aflatoxin gene cluster, but the function of AflN is undefined in Aspergillus flavus. In this study, aflN is knocked out and overexpressed to study the function of AflN. The results indicated that the loss of AflN leads to the defect of aflatoxin biosynthesis. AflN is also found to play a role in conidiation but not hyphal growth and sclerotia development. Moreover, AlfN is related to the response to environmental oxidative stress and intracellular levels of reactive oxygen species. At last, AflN is involved in the pathogenicity of Aspergillus flavus to host. These results suggested that AflN played important roles in aflatoxin biosynthesis, conidiation and reactive oxygen species generation in Aspergillus flavus, which will be helpful for the understanding of aflN function, and will be beneficial to the prevention and control of Aspergillus flavus and aflatoxins contamination.

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