Ochratoxin A in wine consumers in Italy: dietary profiles

2009 ◽  
Vol 2 (3) ◽  
pp. 339-346 ◽  
Author(s):  
L. Gambelli ◽  
L. D'Addezio

The study was carried out on a group of wine consumers, healthy adults, living in one of the areas in Southern Italy, where the ochratoxin A (OTA) levels in wines were very high. OTA levels in consumed wine ranged from 0.2 to 2 ng/ml for 80% of the samples and from 2.10 to 5.40 ng/ml for the other 20%. OTA values in blood (exposure) were lower than 0.28 ng/ml for 30% of the subjects, ranged from 0.28 to 0.34 ng/ml for 43% of the subjects, and reached more than 0.34 ng/ml for 27% of the subjects. Mean OTA measured in urine was 0.43 ng/ml. No significant correlation was found between OTA concentration in blood and in consumed wine, neither between OTA in blood and ingestion levels. OTA levels were determined by HPLC. Individual food consumption habits, gathered in a questionnaire, were studied in association with experimental exposure by means of multiple correspondence analysis. Subjects consuming one or two glasses of red home-produced wine daily were characterised by medium exposure, while those consuming three glasses or half a litre per occasion showed a high exposure; low exposure was associated with weekly consumption of white commercial wine. High quantities of beer and daily consumption of bread and pasta characterised habitual wine consumers, while weekly consumption of beer, bread and chocolate characterised moderate wine consumers.

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Lisa Kakinami ◽  
Marie Lambert ◽  
Lise Gauvin ◽  
Louise Séguin ◽  
Béatrice Nikiéma ◽  
...  

Background: Childhood poverty is associated with poorer food consumption patterns but longitudinal data on this association is limited. To assess if the relationship between food consumption and poverty differs depending on the child’s age and pattern of poverty, we analyzed the relationship between consumption of selected foods and poverty trajectories at various ages in a birth cohort. Methods: The 1998-2010 "Quebec Longitudinal Study of Child Development" (n=2,120) cohort was used for these analyses. Household income was measured annually with poverty defined as income below the low-income thresholds established by Statistics Canada adjusted for household size and geographic region. Frequency of children’s consumption of dairy (milk, cheese, yogurt), fruits, and vegetables were reported by parents using a food frequency questionnaire. Analyses were conducted on the 739 children with food consumption data. Trajectories of poverty at 6, 8, 10, and 12 years were characterized with latent class group analysis using maximum likelihood in a semiparametric mixture model. Multivariable logistic regression predicted the likelihood of having less than 2 servings a day of dairy, fruits and vegetables based on poverty trajectories after adjusting for age and sex. Results: The poverty trajectories were stable and fell into 1 lower exposure category (consistently low exposure (73%, n=537)) and 3 higher exposure categories (increasing: 8%, n=61; decreasing: 10%, n=73; or consistently high exposure: 9%, n=68)). Compared to children experiencing low exposure to poverty, children with increasing or high exposure to poverty were less likely to have at least two servings of fruit a day at all ages, but the results were not significant. Compared to children experiencing low exposure to poverty, children with high exposure were 55% (CI: 0.2-0.8, p=0.001), 31% (CI: 0.4-1.2, p=0.23), 67% (CI: 0.2-0.6, p<.0001), and 49% (CI: 0.3-0.8, p=0.001) less likely to have at least two servings of dairy a day at 6, 8, 10, and 12 years, respectively. Compared to children with low exposure to poverty, children with high exposure were 43% (CI: 0.3-0.9, p=0.02), 46% (CI: 0.3-0.9, p=0.02), 55% (CI: 0.3-0.8, p=0.003), and 47% (CI: 0.3-0.9, p=0.02) less likely to have at least two servings of vegetables a day at 6, 8, 10, and 12 years, respectively. Children at all ages with decreasing or increasing exposure to poverty were less likely to have at least two servings of vegetables a day, but the results were not statistically significant. Conclusion: Experiencing high exposure to poverty has consistent effects on food consumption throughout childhood. In addition, compared to children with low exposure to poverty, children with increasing or decreasing exposure were less likely to have at least 2 servings of fruits and vegetables a day, suggesting any exposure to poverty may have detrimental effects on consumption of selected foods.


1992 ◽  
Vol 25 (2) ◽  
pp. 95-107 ◽  
Author(s):  
R. K. Naidu ◽  
Ambalika Sinha

The impact of four metaphysical beliefs on death anxiety was investigated. Beliefs about the existence and attributes of God, afterlife, and consequences of suffering were chosen for study. It was hypothesized that any belief which assures the individual a continued existence beyond death would reduce the degree of anxiety felt on encountering death-related stimuli. A test including pictures depicting death and non-death scenes was constructed to measure death anxiety. The sample included 120 householders (60 heads of unsettled and 60 heads of settled families). Half of them lived in high exposure to death sight areas and the other half lived in low exposure areas. Subjects from only low exposure areas revealed significant relationships between beliefs and death anxiety. The results of this study suggest that the beliefs play functional roles that are different for people with different needs.


1979 ◽  
Author(s):  
J. G. Kelton ◽  
P. B. Neame ◽  
I. Walker ◽  
A. G. Turpie ◽  
J. McBride ◽  
...  

Thrombotic thrombocytopenic purpura (TTP) is a rare but serious illness of unknown etiology. Treatment by plasmapheresis has been reported to be effective but the mechanism for benefit is unknown. We have investigated the effect of plasmapheresis in 2 patients with TTP by quantitating platelet associated IgG (PAIgG) levels prior to and following plasmapheresis. Both patients had very high levels of PAIgG at presentation (90 and A8 fg IgG/platelet respectively, normal 0-5). in both, the PAIgG levels progressively fell to within the normal range and the platelet count rose following plasmapheresis. One patient remained in remission with normal platelet counts and PAIgG levels. The other relapsed after plasmapheresis and the PAIgG level rose prior to the fall in platelet count. Plasmapheresis was repeated and resulted in normalization of both the platelet count and PAIgG level. It is suggested that plasmapheresis removes antiplatelet antibody or immune complexes which may be of etiological importance in this illness.


1994 ◽  
Vol 29 (7) ◽  
pp. 327-333
Author(s):  
Y. Matsui ◽  
F. Yamaguchi ◽  
Y. Suwa ◽  
Y. Urushigawa

Activated sludges were acclimated to p-nitrophenol (PNP) in two operational modes, a batch and a continuous. The operational mode of the PNP acclimation of activated sludges strongly affected the physiological characteristics of predominant microorganisms responsible for PNP degradation. Predominant PNP degraders in the sludge in batch mode (Sludge B) had lower PNP affinity and were relatively insensitive to PNP concentration. Those of the sludge in continuous mode (Sludge C), on the other hand, had very high PNP affinity and were sensitive to PNP. MPN enumeration of PNP degraders in sludge B and C using media with different PNP concentrations (0.05, 0.2,0.5 and 2.0 mM) supported the above results. Medium with 0.2 mM of PNP did not recover PNP degraders in sludge C well, while it recovered PNP degraders in sludge B as well as the medium with 0.05 mM did. When switching from one operational mode to the other, the predominant population in sludge B shifted to the sensitive group, but that of sludge C did not shift at the given loading of PNP, showing relative resistance to inhibitive concentration.


2019 ◽  
Vol 11 (3) ◽  
pp. 328-341
Author(s):  
Rifki Ismal ◽  
Nurul Izzati Septiana

Purpose The demand for Saudi Arabian real (SAR) is very high in the pilgrimage (hajj) season while the authority, unfortunately, does not hedge the hajj funds. As such, the hajj funds are potentially exposed to exchange rate risk, which can impact the value of hajj funds and generate extra cost to the pilgrims. The purpose of this paper is to conduct simulations of Islamic hedging for pilgrimage funds to: mitigate and minimize exchange rate risk, identify and recommend the ideal time, amount and tenors of Islamic hedging for hajj funds, estimate cost saving by pursuing Islamic hedging and propose technical and general recommendations for the authority. Design/methodology/approach Forward transaction mechanism is adopted to compute Islamic forward between SAR and Rupiah (Indonesian currency) or IDR. Findings – based on simulations, the paper finds that: the longer the Islamic hedging tenors, the better is the result of Islamic hedging, the decreasing of IDR/USD is the right time to hedge the hajj funds and, on the other hand, the IDR/SAR appreciation is not the right time to hedge the hajj funds. Findings Based on simulations, the paper finds that: the longer the Islamic hedging tenors, the better is the result of Islamic hedging, the decreasing of IDR/USD is the right time to hedge the hajj funds and, on the other hand, the IDR/SAR appreciation is not the right time to hedge the hajj funds. Research limitations/implications The research suggests the authority to (and not to) hedge the hajj fund, depending on economic conditions and market indicators. Even though the assessment is for the Indonesian case, other countries maintaining hajj funds might also learn from this paper. Originality/value To the best of author’s knowledge, this is the first paper in Indonesia that attempts to simulate the optimal hedging of hajj funds.


Risks ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 74 ◽  
Author(s):  
Fabiana Gómez ◽  
Jorge Ponce

This paper provides a rationale for the macro-prudential regulation of insurance companies, where capital requirements increase in their contribution to systemic risk. In the absence of systemic risk, the formal model in this paper predicts that optimal regulation may be implemented by capital regulation (similar to that observed in practice, e.g., Solvency II ) and by actuarially fair technical reserve. However, these instruments are not sufficient when insurance companies are exposed to systemic risk: prudential regulation should also add a systemic component to capital requirements that is non-decreasing in the firm’s exposure to systemic risk. Implementing the optimal policy implies separating insurance firms into two categories according to their exposure to systemic risk: those with relatively low exposure should be eligible for bailouts, while those with high exposure should not benefit from public support if a systemic event occurs.


2021 ◽  
Vol 13 (13) ◽  
pp. 7393
Author(s):  
Agata Nicolosi ◽  
Donatella Di Gregorio ◽  
Giuseppe Arena ◽  
Valentina Rosa Laganà ◽  
Donatella Privitera

The study looks at the problems facing coastal fishing communities. It highlights the impacts that, in the complex framework of the EU reforms, have manifested themselves on economic activities and on society. The aim of the paper is twofold: to examine small-scale artisanal fishing in an area of Southern Italy in order to develop resilience and diversification and at the same time to outline the profiles of local bluefish buyers to highlight development strategies for the sector. The research carried out through a direct survey by administering a questionnaire to fishermen operating in areas of Southern Italy and the data cross-referenced with the opinions of local consumers. A conjoint experiment, followed by a multiple correspondence analysis and cluster identification, was used to outline the profiles of local bluefish buyers. The results of the analysis reveal that the fish market and the restaurant sector are the main distribution channels preferred by fishermen. Furthermore, fishermen are very sensitive to environmental issues and are willing to collaborate and actively participate in the environmental protection of the sea. Consumers recognise the quality of local bluefish, and they implicitly perceive the sustainability of the method of capture. The results show the need to undertake synergistic actions for the fishing industry, capable of activating marketing strategies adequately to support, promote and develop the sector. The results of the study provide helpful information for food companies in order to better segment their market and target their consumers, as well as to effectively promote their product using brands, certifications and traceability.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S319-S319
Author(s):  
Jessica Howard-Anderson ◽  
Carly Adams ◽  
Amy C Sherman ◽  
William C Dube ◽  
Teresa C Smith ◽  
...  

Abstract Background Healthcare personnel (HCP) may be at increased risk for COVID-19, but differences in risk by work activities are poorly defined. Centers for Disease Control and Prevention recommends cohorting hospitalized patients with COVID-19 to reduce in-hospital transmission of SARS-CoV-2, but it is unknown if occupational and non-occupational behaviors differ based on exposure to COVID-19 units. Methods We analyzed a subset of HCP from an ongoing CDC-funded SARS-CoV-2 serosurveillance study. HCP were recruited from four Atlanta hospitals of different sizes and patient populations. All HCP completed a baseline REDCap survey. We used logistic regression to compare occupational activities and infection prevention practices among HCP stratified by exposure to COVID-19 units: low (0% of shifts), medium (1–49% of shifts) or high (≥50% of shifts). Results Of 211 HCP enrolled (36% emergency department [ED] providers, 35% inpatient RNs, 17% inpatient MDs/APPs, 7% radiology technicians and 6% respiratory therapists [RTs]), the majority (79%) were female and the median age was 35 years. Nearly half of the inpatient MD/APPs (46%) and RNs (47%) and over two-thirds of the RTs (67%) worked primarily in the ICU. Aerosol generating procedures were common among RNs, MD/APPs, and RTs (26–58% performed ≥1), but rare among ED providers (0–13% performed ≥1). Compared to HCP with low exposure to COVID-19 units, those with medium or high exposure spent a similar proportion of shifts directly at the bedside and were about as likely to practice universal masking. Being able to consistently social distance from co-workers was rare (33%); HCP with high exposure to COVID-19 units were less likely to report social distancing in the workplace compared to those with low exposure; however, this was not significantly different (OR 0.6; 95% CI: 0.3, 1.1). Concerns about personal protective equipment in COVID-19 units were similar across levels of exposure (Table 1). Table 1: Occupational activities and infection prevention behaviors of healthcare personnel stratified by level of exposure to COVID-19 units Conclusion The proportion of time spent in dedicated COVID-19 units did not appear to influence time HCP spend directly at the bedside or infection prevention practices (social distancing and universal masking) in the workplace. Risk for SARS-CoV-2 infection in HCP may depend more on factors acting at the individual level rather than those related to location of work. Disclosures Jessica Howard-Anderson, MD, Antibacterial Resistance Leadership Group (ARLG) (Other Financial or Material Support, The ARLG fellowship provides salary support for ID fellowship and mentored research training) Ben Lopman, PhD, MSc, Takeda Pharmaceuticals (Advisor or Review Panel member, Research Grant or Support, Other Financial or Material Support, Personal fees)World Health Organization (Advisor or Review Panel member, Other Financial or Material Support, Personal fees for technical advice and analysis)


2005 ◽  
Vol 495-497 ◽  
pp. 603-608 ◽  
Author(s):  
Atsushi Todayama ◽  
Hirosuke Inagaki

On the basis of Taylor-Bishop-Hill’s theory, many previous theoretical investigations have predicted that, at high rolling reductions, most of orientations should rotate along theβfiber from {110}<112> to {123}<634> and finally into the {112}<111> stable end orientations. Although some exceptions exist, experimental observations have shown, on the other hand, that the maximum on the β fiber is located still at about {123}<634> even after 97 % cold rolling. In the present paper, high purity Al containing 50 ppm Cu was cold rolled up to 99.4 % reduction in thickness and examined whether {112}<111> stable end orientation could be achieved experimentally. It was found that, with increasing rolling reduction above 98 %, {110}<112> decreased, while orientations in the range between {123}<634> and {112}<111> increased, suggesting that crystal rotation along the βfiber from {110}<112> toward {123}<634> and {112}<111> in fact took place. At higher rolling reductions, however, further rotation of this peak toward {112}<111> was extremely sluggish, and even at the highest rolling reduction, it could not arrive at {112}<111>. Such discrepancies between theoretical predictions and experimental observations should be ascribed to the development of dislocation substructures, which were formed by concurrent work hardening and dynamic recovery. Since such development of dislocation substructures are not taken into account in Taylor-Bishop-Hill’s theory, it seems that they can not correctly predict the development of rolling textures at very high rolling reductions, i. e. stable end orientations. On annealing specimens rolled above 98 % reduction in thickness, cube textures were very weak, suggesting that cube bands were almost completely rotated into other orientations during cold rolling. {325}<496>, which lay at an intermediate position between {123}<634> and {112}<111> along theβfiber, developed strongly in the recrystallization textures.


1953 ◽  
Vol 31 (2) ◽  
pp. 171-181 ◽  
Author(s):  
D. W. R. McKinley ◽  
Peter M. Millman

In the course of the Ottawa meteor program some unusual echoes have been detected on 33 Mc. Echoes from the aurora are discussed and correlated with visual observations. Two mechanisms of radio reflections from the aurora have been proposed but the data here presented are insufficient to favor one over the other. On Aug. 4, 1948, six extremely long duration meteor echoes were observed which may have been due to abnormal ionospheric conditions. From time to time since August, 1948, a weak semipermanent echo has been recorded, usually appearing at a range of about 80 km., and enduring up to an hour. It is suggested that this echo is due to back-scatter from the same sources in the lower E-region that are presumed to be responsible for long-range very high frequency propagation.


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