Electrospinning

Author(s):  
Tyler Allee ◽  
Andrew Handorf ◽  
Wan-Ju Li

In this chapter authors explain electrospinning technique and how to involve electrospinning technique in biomedical engineering. It is a materials processing technique that uses an electric field to draw a polymer solution into ultra-fine fibers.   Further, this chapter aims to provide important information to researchers who aim to use electrospinning in their research. The electrospinning technique was invented a few decades ago and has recently been modified for biomedical applications.

2019 ◽  
Vol 15 (3) ◽  
pp. 356-360
Author(s):  
Muhammad Syhamiel Iqhwan Rusli ◽  
Mohd Izzat Hassan ◽  
Naznin Sultana ◽  
Ahmad Fauzi Ismail

Polycaprolactone (PCL) is one of the synthetic polymers used in biomedical applications.  PCL has several advantages including biocompatibility, biodegradability and mechanical flexibility. On the other hand, zeolites are microporous, aluminosilicate minerals commonly used as commercial adsorbents.  Electrospinning is a promising technique to produce membranes by applying high voltage electricity. In this research, an electrospinning technique was used to fabricate the electrospun membrane based on PCL and zeolite.  In order to produce electrospun membrane, 15% (w/v) of PCL polymer solution was dissolved in acetone and 20% (w/v) zeolite was incorporated into the PCL polymer solution.  The diameter range of fiber was 2-6 µm. Zeolite nanoparticles were distributed homogenously into the fibers.  EDX spectrum confirmed the presence of zeolite throughout the membrane. Mechanical testing revealed that the bi-layered membrane had better mechanical properties than only PCL and PCL/Zeolite membrane. In-vitro degradation experiment was carried out for 21 days and the membranes were characterized after the experiment. The membrane can be potentially used as microfiltration unit to entrap silver contaminants in drinking water.  Apart of that, the membranes are prepared with biodegradable, biocompatible, non-toxic materials which are eco-friendly.


Author(s):  
N. Sultana ◽  
M. S. I. Rusli ◽  
M. I. Hassan

The presence of heavy metals in drinking water leads to several health problems. Nano and micro fiber membranes can be used to overcome this through nano or microfiltration process. In this study, polycaprolactone (PCL)/zeolite electrospun composite membranes were fabricated and characterized. PCL is one of the synthetic polymers used in biomedical applications. It has several advantages, including biocompatibility, biodegradability and mechanical flexibility. On the other hand, zeolites are microporous, aluminosilicate minerals commonly used as commercial adsorbents. Electrospinning is a promising technique to produce membranes by applying high voltage electricity. In this research, an electrospinning technique was used to fabricate the electrospun membrane based on PCL and zeolite. In order to produce electrospun membrane, 15% (w/v) of PCL polymer solution was dissolved in acetone and 20% (w/v) zeolite nanoparticles were incorporated into the PCL polymer solution. The diameter range of fiber was 2-6 µm. Zeolite nanoparticles were distributed homogenously into the fibers. EDX spectrum confirmed the presence of zeolite throughout the membrane. From the performance testing, it was revealed that the membrane can be potentially used as microfiltration to entrap silver contaminants in drinking water. Apart of that, the membranes are prepared with biocompatible, non-toxic materials which can be eco-friendly.


10.14311/1033 ◽  
2008 ◽  
Vol 48 (4) ◽  
Author(s):  
Y. Klenko ◽  
V. Scholtz

Point-to-plane corona discharge is widely used for modifying polymer surfaces for biomedical applications and for sterilization and decontamination. This paper focuses on an experimental investigation of the influence of the single-point and multi-point corona discharge electric field on gel surface. Three types of gelatinous agar were used as the gel medium: blood agar, nutrient agar and Endo agar. The gel surface modification was studied for various time periods and discharge currents. 


2018 ◽  
Vol 10 (14) ◽  
pp. 11529-11538 ◽  
Author(s):  
Qiang Chen ◽  
Jiajia Jing ◽  
Hongfei Qi ◽  
Ifty Ahmed ◽  
Haiou Yang ◽  
...  

2017 ◽  
Vol 79 (1-2) ◽  
Author(s):  
Muhammad Syhamiel Iqhwan Che Rusli ◽  
Mohd Izzat Hassan ◽  
Naznin Sultana ◽  
Ahmad Fauzi Ismail

The presence of heavy metals in drinking water leads to several health problems. In this study, polycaprolactone (PCL)/zeolite nano or microfiber electrospun composite membranes, diameter range of the fibers was 2 µm- 6 µm, were fabricated by using electrospinning technique. The membranes separation processes have played very crucial roles in water purification industry. Apart from that, the membranes are prepared with biocompatible, non-toxic materials which will be eco-friendly. In order to produce electrospun membrane, 15% (w/v) of PCL polymer solution was dissolved in acetone and 20% (w/w) zeolite was incorporated into the PCL polymer solution. Electricity charged jet of polymer solution from the syringe formed an electrostatics field when the high voltage of 20kV was applied. Scanning electron micrograph (SEM) and energy dispersive spectroscopy (EDX) implemented to indicate the characterization of membranes. The water contact angle of PCL/zeolite membrane was 119.53±5.24 which was almost same as pure PCL membrane (107.73±8.54). The inducible results obtained in this study suggested that electrospun pcl and polycaprolactone/zeolite layer by layer nanofibrous membranes can be a favored verdict for the removal of heavy metal ions.


Gels ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. 20 ◽  
Author(s):  
Sobhan Ghaeini-Hesaroeiye ◽  
Hossein Razmi Bagtash ◽  
Soheil Boddohi ◽  
Ebrahim Vasheghani-Farahani ◽  
Esmaiel Jabbari

Nanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogels is their tunable responsiveness to external stimuli. In this review, thermosensitive nanogels are discussed, with a focus on moieties in their chemical structure which are responsible for thermosensitivity. These thermosensitive moieties can be classified into four groups, namely, polymers bearing amide groups, ether groups, vinyl ether groups and hydrophilic polymers bearing hydrophobic groups. These novel thermoresponsive nanogels provide effective drug delivery systems and tissue regeneration constructs for treating patients in many clinical applications, such as targeted, sustained and controlled release.


1999 ◽  
Vol 14 (7) ◽  
pp. 2940-2944 ◽  
Author(s):  
Fei Fang ◽  
Wei Yang ◽  
Ting Zhu

Lanthanum-modified lead zirconate titanate ferroelectric ceramics (Pb0.96La0.04)(Zr0.40Ti0.60)0.99O3 were synthesized by the conventional powder processing technique. X-ray diffraction experiments revealed that the samples belong to the tetragonal phase with a = b = 0.4055 nm, c = 0.4109 nm, and c/a = 1.013. After being poled, the samples were indented with a 5-kg Vickers indenter, and lateral electric fields of 0.4 Ec, 0.5 Ec, and 0.6 Ec (Ec = 1100 V/mm) were applied, respectively. Field-emission scanning electron microscopy showed that 90° domain switching appeared near the tip of the indentation crack under a lateral electric field of 0.6 Ec. A mechanism of 90° domain switching near the crack tip under an electric field is discussed.


2011 ◽  
Vol 279 ◽  
pp. 214-218 ◽  
Author(s):  
Hong Wei Duan ◽  
Jin Gang Jiang

Electrospinning technique is currently one of the most important methods for preparing nanofiber. Aiming to the fact that the electric field at the receiver is relatively weak, the electric field’s distribution in the typical electrospinning device was calculated and analyzed by ANSYS. It put forward the method of optimizing electric field’s distribution by using an assistant electric field device. At the same boundary conditions, the electric field’s distribution in the original device and improved binode device are compared. The simulation analysis provides an effective reference for the optimization design of electric field’s distribution in the electro-spinning device. The experimentation results show that the distribution of fiber diameter of polyimide non-woven fabric is equal and has a certain directivity after adding assistant electric field.


2008 ◽  
Vol 5 (27) ◽  
pp. 1255-1261 ◽  
Author(s):  
Z Ahmad ◽  
H.B Zhang ◽  
U Farook ◽  
M Edirisinghe ◽  
E Stride ◽  
...  

In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.


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