The Chemical Constituents, Anti-Inflammatory, Anti-Oxidant, and Ethnomedicinal Properties of Aloe barbadensis

2022 ◽  
pp. 454-471
Author(s):  
Dickson Adom ◽  
Paul Appiah Sekyere ◽  
Mohan Kumar Krishnappa
Keyword(s):  
Chemical Constituents ◽  
Aloe Vera ◽  
Document Analysis ◽  
The Body ◽  
Extensive Review ◽  
Aloe Barbadensis ◽  
Succulent Plant ◽  
History Of ◽  
Anti Oxidant ◽  
Anti Inflammatory

Aloe vera is a perennial, drought-resisting, succulent plant belonging to the Asphodelaceae family that has a long history of having many tremendous medicinal and anti-inflammatory as well as anti-bacterial properties. This chapter highlights the great potentials of the aloe vera species. Desk study and document analysis guided the systematic and extensive review of both published and unpublished resources on the Aloe vera Species. The chapter contends that horticulturists and plant scientists in the field of agriculture and medicine must pay attention to the Aloe vera as a medicinal plant that possesses the most powerful antibacterial and anti-inflammatory properties, which protects the body against constipation through enhancing the body metabolism, skin, and worm infestations.

The Chemical Constituents, Anti-Inflammatory, Anti-Oxidant, and Ethnomedicinal Properties of Aloe barbadensis

2020 ◽  
pp. 181-198
Author(s):  
Dickson Adom ◽  
Paul Appiah Sekyere ◽  
Mohan Kumar Krishnappa
Keyword(s):  
Chemical Constituents ◽  
Aloe Vera ◽  
Document Analysis ◽  
The Body ◽  
Extensive Review ◽  
Aloe Barbadensis ◽  
Succulent Plant ◽  
History Of ◽  
Anti Oxidant ◽  
Anti Inflammatory

Aloe vera is a perennial, drought-resisting, succulent plant belonging to the Asphodelaceae family that has a long history of having many tremendous medicinal and anti-inflammatory as well as anti-bacterial properties. This chapter highlights the great potentials of the aloe vera species. Desk study and document analysis guided the systematic and extensive review of both published and unpublished resources on the Aloe vera Species. The chapter contends that horticulturists and plant scientists in the field of agriculture and medicine must pay attention to the Aloe vera as a medicinal plant that possesses the most powerful antibacterial and anti-inflammatory properties, which protects the body against constipation through enhancing the body metabolism, skin, and worm infestations.

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

Pharmacological activities and Therapeutic potential of kaempferitrin in medicine for the treatment of human disorders: A review of medicinal importance and health benefits

2021 ◽  
Vol 21 ◽  
Author(s):  
Dinesh Kumar Patel
Keyword(s):  
Broiler Chickens ◽  
Therapeutic Potential ◽  
Scientific Information ◽  
Aloe Vera ◽  
Crocus Sativus ◽  
Related Complication ◽  
Food Material ◽  
Biological Potential ◽  
Anti Oxidant ◽  
Anti Inflammatory

Background: Herbal drugs and their derived phytochemicals are valuable for human being as a source of vital component of food material and drugs. Flavonoids are naturally occurring phytochemical produced in plants through metabolisms and they are having anti-hyperlipidemia, anti-inflammatory, anti-oxidant and anti-apoptotic activity. Flavonoids have been identified in the fruits, nuts, vegetables, seeds, stem, flowers and tea. Kaempferol is a natural flavonoidal compound present in edible plants such as apples, broccoli, strawberries, beans, grapefruit, propolis and medicinal plants such as Aloe vera, Ginkgo biloba, Rosmarinus officinalis, Crocus sativus L., Hypericum perforatum L. Kaempferol have anti-oxidant, anti-inflammatory, anti-apoptotic, pro-apoptotic, cardio-protective and anti-cancer activities. Methods: Glycosides of kaempferol such as kaempferitrin also called kaempferol 3,7-dirhamnoside are known to be more abundant than their flavonoid monomers in plants. Various literature databases have been searched to collect all the scientific information of kaempferitrin in the present investigation and analyzed in order to know the therapeutic benefit and biological potential of kaempferitrin. Moreover all the information has been presented here in two broad sections i.e. pharmacological and analytical. Results: From the analysis of all the collected and presented information, it was found that kaempferitrin has potent insulin-mimetic potential and could be used for the treatment of diabetes and related complication. However, it has also shown anti-oxidant, anti-inflammatory, anti-convulsant, anti-osteoporotic, anti-depressant, anthelmintic, immunostimulatory and natriuretic properties and inhibits cell proliferation and apoptosis. Kaempferitrin also improves meat quality of broiler chickens. Conclusions: The presented information in this work will be valuable to justify the biological importance and therapeutic potential of kaempferitrin in the scientific field.

scholarly journals TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

2016 ◽  
Vol 9 (5) ◽  
pp. 21
Author(s):  
Varun Garg ◽  
Barinder Kaur ◽  
Sachin Kumar Singh ◽  
Bimlesh Kumar
Keyword(s):  
Chemical Constituents ◽  
Present Review ◽  
Terminalia Chebula ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

scholarly journals The therapeutic efficacy of Aloe vera gel ointment on staphylococcal pyoderma in dogs

2020 ◽  
Vol 13 (11) ◽  
pp. 2371-2380
Author(s):  
Ahmed Kamr ◽  
Ali Arbaga ◽  
Amanallah El-Bahrawy ◽  
Ahmed Elsify ◽  
Hadeer Khaled ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Aloe Vera ◽  
Inhibition Zone ◽  
Complete Healing ◽  
Aloe Barbadensis ◽  
Local Breed ◽  
Aloe Vera Gel ◽  
Antioxidant Parameters ◽  
Anti Inflammatory ◽  
Factor Α

Background and Aim: Staphylococcus pyoderma is a common problem in dogs that need a novel treatment rather than antibiotic therapy. The aim of this study was to investigate the therapeutic efficacy, anti-inflammatory, and antioxidative properties of Aloe vera (Aloe barbadensis) gel ointment on dogs' Staphylococcus pyoderma compared to gentamicin ointment. Materials and Methods: The inhibition zone of A. vera extract 20% and 40% and gentamicin 1% against Staphylococcus aureus was determined on well diffusion agar. Twenty Baladi local breed dogs were used as control negative group before intradermal inoculation with 105 CFU S. aureus. The animals were classified into four equal groups, control positive group without treatment (n=5), treated groups by 20% A. vera gel ointment (n=5), 40% A. vera gel ointment (n=5), and gentamicin ointment 1% (n=5). Topical application of A. vera and gentamicin ointments was carried out twice daily for 2 weeks until complete healing of dogs' pyoderma. Clinical evaluation was recorded. Inflammatory, oxidant, and antioxidant parameters were measured in serum. Results: The inhibition zone of A. vera extracts 20% and 40% was 19 mm and 23 mm, respectively, while gentamicin 1% was 18 mm. The half maximal inhibitory concentration (of A. vera 20% and 40% were 13.70 with R2=0.98. Dogs' pyoderma treated with A. vera gel ointment 20% and 40% were more likely to have low haptoglobin and tumor necrosis factor-α concentrations than gentamicin 1% ([odds ratio [OR]=4.6; 95% confidence interval [CI]=1.31-17.40; p<0.05]; [OR=5.2; 95% CI=1.04-22.30; p<0.05]), respectively. Conclusion: It seems evident that A. vera has therapeutic effect, antibacterial, and anti-inflammatory effects against dogs' staphylococcal pyoderma than gentamicin that would support its further use rather than antibiotics in one health arena.

Anti-Apoptotic and Anti-Inflammatory Activities of Edible Fresh Water Algae Prasiola japonica in UVB-Irradiated Skin Keratinocytes

2019 ◽  
Vol 47 (08) ◽  
pp. 1853-1868
Author(s):  
Eunju Choi ◽  
Young-Su Yi ◽  
Jongsung Lee ◽  
Sang Hee Park ◽  
Sunggyu Kim ◽  
...  
Keyword(s):  
Fresh Water ◽  
Ethanol Extract ◽  
The Body ◽  
Hacat Cells ◽  
Protective Effects ◽  
Proteolytic Activation ◽  
Skin Keratinocytes ◽  
External Stresses ◽  
Anti Oxidant ◽  
Anti Inflammatory

Skin is the outer tissue layer and is a barrier protecting the body from various external stresses. The fresh water green edible algae Prasiola japonica has antiviral, antimicrobial, and anti-inflammatory properties; however, few studies of its effects on skin-protection have been reported. In this study, Prasiola japonica ethanol extract (Pj-EE) was prepared, and its skin-protective properties were investigated in skin keratinocytes. Pj-EE inhibited ROS production in UVB-irradiated HaCaT cells without cytotoxicity. Pj-EE also suppressed the apoptotic death of UVB-irradiated HaCaT cells by decreasing the generation of apoptotic bodies and the proteolytic activation of apoptosis caspase-3, -8, and -9. Moreover, Pj-EE downregulated the mRNA expression of the inflammatory gene cyclooxygenase-2 (COX-2), the pro-inflammatory cytokine genes interleukin (IL)-1[Formula: see text], IL-8, IL-6, tumor necrosis factor (TNF)-[Formula: see text], and interferon (IFN)-[Formula: see text], and the tissue remodeling genes matrix metalloproteinase (MMP)-1, -2, -3, and -9. The Pj-EE-induced anti-inflammatory effect was mediated by suppressing the activation of nuclear factor-kappa B (NF-[Formula: see text]B) signaling pathway in the UVB-irradiated HaCaT cells. Taken together, these results suggest that Pj-EE exerts skin-protective effects through anti-oxidant, anti-apoptotic, and anti-inflammatory activities in skin keratinocytes.

Evaluation of Anticonvulsant and Anti-oxidant Potentials of Basella Alba by Influencing the Brain Enzyme Levels in Laboratory Animals

2020 ◽  
Vol 11 (3) ◽  
pp. 5031-5034
Author(s):  
Asokan B.R. ◽  
Jaikumar S ◽  
Somasundaram G
Keyword(s):  
Neurological Diseases ◽  
Chemical Constituents ◽  
The Body ◽  
Laboratory Animals ◽  
Basella Alba ◽  
Protective Enzyme ◽  
Anti Oxidant ◽  
Radical Generation ◽  
Brain Tissue Damage ◽  
The Brain

Epilepsy and convulsions constitute a significant class of symptoms that are commonly seen in many neurological diseases. It is understood that there is an apparent alteration in the levels of the enzymes which present brain during epilepsy. Anti-oxidant drugs are known to elevate the protective enzyme levels in the body and restore them to ensure the proper functioning is done. But when the enzyme levels are not managed properly, they can cause further damage and deterioration of the tissue. Basella alba is one of such drugs, which is rich in anti-oxidant chemical constituents. Many researchers concluded that many components like vitamin A, C and flavonoids, polyphenols are being reported. In the study, Basella alba was investigated for effect on an anti-oxidant enzyme in the brain. The extracts showed a better activity and prevented the brain tissue damage from any oxidative free radical generation. The enzyme levels were healthy at the dose of 400mg/kg of extract.

scholarly journals Syzygium Samarangense : A Review on its Pharmacognostical, Pharmacological and Phytochemical Proৎile

2020 ◽  
Vol 11 (4) ◽  
pp. 6066-6078
Author(s):  
Greeshma G Nair ◽  
Sathianarayanan S
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Human Colon ◽  
Salmonella Typhi ◽  
Cytotoxic Activities ◽  
Human Colon Cancer ◽  
Whole Plant ◽  
The Family ◽  
Anti Oxidant ◽  
Anti Inflammatory

The objective of this review is to document briefly about the chemical constituents, pharmacognostical evaluation and biological activities of Syzygium samarangense belongs to the family Myrtaceae. It is generally called Java Apple, Wax Apple, Blume, Chambekka etc. Syzygium samarangense traditionally used as an astringent. It is also used to treat fever and halt diarrhea. The whole plant contains flavonoids, terpenoids, tannins, phenolic compounds, gallic acid, ellagic acid, squalene, botulin, lupeol, sitosterol, mixture of cycloartenol stearate, lupenyl stearate, β-sitosterol stearate, vitamins and minerals which bearing anti-oxidant, anti- microbial, hypoglycemic, anti-inflammatory, Immunomodulatory, CNS, Anti- diarrheal, anthelmintic and cytotoxic activities. In this review, different parts of the plant, their phytochemical constituents and their corresponding biological activities have been explored. The literatures reported that the fruit part contains carotene, anthocyanin and vescalagin which is used as antioxidant, anti- microbial and hypoglycemic effect. The leaf part contains myricetin, strobopinine, epigallocatechin, aurentiacin which bearing anti-inflammatory and immunomodulatory effect. The alcoholic extracts of leaves, seeds, root bearing analgesic, anti- inflammatory effect in lipopolysaccharide, antioxidant, cytotoxic activity against human colon cancer cell, the studies revealed that the extracts showed a potent anti- microbial activity against salmonella typhi, Escherichia coli, pseudomonas aeruginosa, bacillus subtilis, candida albicans etc. The aqueous extract of fruit prevents diabetes mellitus in rats.

scholarly journals ALOE VERA: A MEDICINAL HERB

2015 ◽  
Vol 3 (11) ◽  
pp. 32-34
Author(s):  
ShailBala Sanghi
Keyword(s):  
Immune System ◽  
Aloe Vera ◽  
Medicinal Herb ◽  
Peptic Ulcers ◽  
Aging Effects ◽  
The World ◽  
Anti Oxidant ◽  
Anti Inflammatory

Aloe vera is a herb distributed all over the world. The herb is used internally to counter most   of the problems of digestion, diabetes, immune system, and peptic ulcers. It also contains anti-bacterial, anti-septic, anti-viral, anti-inflammatory, anti-tumor, anti -oxidant, moisturizing, anti-aging effects.  This review highlights the importance of using Aloe vera as a medicinal herb.

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