Nutrition

2022 ◽  
pp. 253-269
Author(s):  
Muhammad Haseeb Ahmad ◽  
Muhammad Faizan Afzal ◽  
Muhammad Imran ◽  
Muhammad Kamran Khan ◽  
Nazir Ahmad
Keyword(s):  
Immune System ◽  
Immune Cells ◽  
Fruits And Vegetables ◽  
Eating Habits ◽  
Black Pepper ◽  
Pivotal Role ◽  
Plant Source ◽  
Host Health ◽  
Different Types

Nutrition is a known aspect that plays a pivotal role in the strengthening of the immune system. Populations with poor eating habits have more risk of severe COVID-19. Micronutrients such as vitamins, including vitamins A, B complex, C, D, and E; minerals including, zinc, selenium, magnesium, and copper are mainly present in plant based foods like legumes, fruits, and vegetables to build different types of immune cells that are helpful in supporting the immune system and promote the host health. Insufficient consumption of these nutrients may result to reduce the resistance to infections as well as an increasing in disease load. Garlic, black pepper, and basel leaves are known as ancient herbs which is helpful to boost the immunity. Numerous studies observed that a powerful antioxidant bioflavonoid quercetin and a glutathione may prevent the risk of COVID-19. In conclusion, foods from plant source show a vigorous role to boost the immunity for all aged groups to control COVID-19.

scholarly journals Potential roles of N6-methyladenosine (m6A) in immune cells

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Chang Liu ◽  
Zhe Yang ◽  
Rong Li ◽  
Yanju Wu ◽  
Ming Chi ◽  
...  
Keyword(s):  
Immune System ◽  
Immune Responses ◽  
Immune Cells ◽  
Mammalian Cells ◽  
Transcriptional Regulator ◽  
Human Diseases ◽  
Pivotal Role ◽  
First Line ◽  
Rna Molecules ◽  
Different Types

AbstractN6-methyl-adenosine (m6A) is one of the most common internal modifications on RNA molecules present in mammalian cells. Deregulation of m6A modification has been recently implicated in many types of human diseases. Therefore, m6A modification has become a research hotspot for its potential therapeutic applications in the treatment of various diseases. The immune system mostly involves different types of immune cells to provide the first line of defense against infections. The immunoregulatory network that orchestrate the immune responses to new pathogens plays a pivotal role in the development of the disease. And m6A modification has been demonstrated to be a major post-transcriptional regulator of immune responses in cells. In this review, we summarize the participants involved in m6A regulation and try to reveal how m6A modification affects the immune responses via changing the immunoregulatory networks.

scholarly journals Role of immune cells in the ocular manifestations of pemphigoid diseases

2019 ◽  
Vol 11 ◽  
pp. 251584141986812
Author(s):  
Tanima Bose
Keyword(s):  
Immune System ◽  
Immune Cells ◽  
Γδ T Cells ◽  
Adaptive Immune System ◽  
Mucous Membrane Pemphigoid ◽  
Adaptive Immune ◽  
Ocular Manifestations ◽  
Different Types ◽  
Ocular Distribution

Pemphigoid disease is classified according to the phenotypical location of the disease and the presence of different types of antibodies. The ocular distribution of pemphigoid mainly occurs in patients with bullous pemphigoid and mucous membrane pemphigoid. Several immune cells, including the cells of the innate immune system (neutrophils and γδ T cells) and the adaptive immune system (T and B cells), are involved in pemphigoid disease. The treatment of pemphigoid is still wide-ranging, and the most utilized treatment is the use of immunosuppressants and corticosteroids. In this scenario, it is absolutely important to screen the immune cells that are involved in this group of diseases and to determine if a targeted treatment approach is plausible. In conclusion, this review will identify some newer treatment possibilities for the whole spectrum of pemphigoid diseases.

scholarly journals Saudi community care awareness food facts, nutrients, immune system and Covid-19 prevention in Taif City among different age categories

2021 ◽  
Vol 21` (01) ◽  
pp. 17213-17233
Author(s):  
Rokayya Sami ◽  
◽  
G Alshehry ◽  
E Elgarni ◽  
M Helal ◽  
...  
Keyword(s):  
Immune System ◽  
Fast Food ◽  
Fruits And Vegetables ◽  
Health Knowledge ◽  
Eating Habits ◽  
Positive Impact ◽  
Smoking Habit ◽  
Mineral Supplement ◽  
Star Anise ◽  
Order Of Magnitude

In December 2019, a new coronavirus was discovered in China, sparking a serious pandemic of human acute respiratory syndrome which spread worldwide at a fast rate. Public health knowledge and awareness is required on food facts, nutrients and immune system for coronavirus prevention.The study designed to investigate COVID-19 impact on dietary intake, knowledge, habits, activities and lifestyle among the people in Taif City. Data collection was conducted from the 4thto the 29thof June 2020. A total of 312 respondents, aged from ≤ 12 to ≥ 65 years were involved in the survey.About81%of the respondents were with high education level (bachelor's degree or higher). Results show that the most frequent diseases in descending order of magnitude were obesity, dental problems, high blood pressure, diabetes, low immunity and colon problems. Data collected showed an increase in food intake frequency during the epidemic except for (4.44, 41.82,12.86, and 30.51 %), like fish, bread, pasta and fast food,respectively. Two hundred and eight (208)of the respondents preferred to use olive oil in their diet due to its several benefits. The majority of the respondents preferred star anise (124) followed by sagebrush (44) as herbal drinks in descending order, respectively. During the COVID-19 pandemic,the study population reported to eat more herbs such as garlic (169), ginger (152) and curcuma (103)to enhance the immune system. Multivitamin (66) and vitamin D intake were reported as the highest, while vitamin B Group and ascorbic acid recorded similar intakes values. Mineral supplement intake in descending order were reported as calcium (57), iron (37) zinc (29) and selenium (5). Around 119 of the respondents had no knowledge on the exact source of COVID-19, while 113 reported as an infection from a bat to humans. The respondents recognized the symptoms as fever (270) and shortness of breath (249). Observing social distance and hand washing were chosen by most respondents (301) as a way of preventing the infection. Two cases of smokers quit the smoking habit; a minor increase rate of training activity was reported; almost all of the respondents embraced the consumption of functional foods, oils, herbs, roots, colored fruits and vegetables and special supplements during COVID-19. Knowledge oncovid-19 had significant positive impact on the respondents’ healthy eating habits, physical exercise, water intake and reduced smoking. Findings recommended intensifying efforts in sensitizing the public to a better understanding of the COVID-19 pandemic and strengthening the immune system.

scholarly journals Sex Hormones and Immune Dimorphism

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Aruna Bhatia ◽  
Harmandeep Kaur Sekhon ◽  
Gurpreet Kaur
Keyword(s):  
Immune System ◽  
Sex Hormones ◽  
Immune Cells ◽  
Reproductive System ◽  
Hormone Receptors ◽  
Review Article ◽  
The Body ◽  
Pathological Conditions ◽  
Different Types ◽  
Major Factors

The functioning of the immune system of the body is regulated by many factors. The abnormal regulation of the immune system may result in some pathological conditions. Sex hormones of reproductive system are one of the major factors that regulate immune system due to the presence of hormone receptors on immune cells. The interaction of sex hormones and immune cells through the receptors on these cells effect the release of cytokines which determines the proliferation, differentiation, and maturation of different types of immunocytes and as a result the outcome of inflammatory or autoimmune diseases. The different regulations of sex hormones in both sexes result in immune dimorphism. In this review article the mechanism of regulation of immune system in different sexes and its impact are discussed.

scholarly journals Microbiome and Probiotics inHealth and HIV Infection

2017 ◽  
Author(s):  
Chiara D'Angelo ◽  
Marcella Reale ◽  
Erica Costantini
Keyword(s):  
Immune System ◽  
Gut Microbiota ◽  
Hiv Infection ◽  
Immune Cells ◽  
Immunomodulatory Activity ◽  
Host Immune System ◽  
Mucus Layer ◽  
Intestinal Immune System ◽  
Different Types ◽  
Bowel Disorders

Microbiota plays a key role in various body’s functions, physiological, metabolic and immunological processes, through different mechanisms such as the regulation of the development and/or functions of different types of immune cells in the intestines. Several evidences indicate that alteration in the gut microbiota can influence infectious and non-infectious diseases. Bacteria that resides on the mucosal surface or within the mucus layer participate in interactions with the host immune system, and a healthy gut microbiota is essential for the development of mucosal immunity. The immunomodulatory activity of probiotics has been proposed in several bowel disorders or in aging-related dysfunctions. In HIV infected patients, the intestinal immune system is affected and inflammation persists during ART therapy too. Several studies are in progress to investigate the ability of probiotics to modulate epithelial barrier functions, microbiota composition and microbial translocation in HIV infection. This mini-review aims to suggest how the use of probiotics is beneficial not only in maintaining a healthy status but also to improve conditions in HIV subjects.

scholarly journals Food habits of the population of Kenitra city

2020 ◽  
Vol 10 (8) ◽  
pp. 828
Author(s):  
Rahma Erahioui ◽  
Hassna Jaber ◽  
Sultana Inekach ◽  
Noureddine Rhaim ◽  
Zakaria Mennane ◽  
...  
Keyword(s):  
Food Habits ◽  
Fruits And Vegetables ◽  
Eating Habits ◽  
Target Population ◽  
Acid Base ◽  
Third Place ◽  
Dried Fruits ◽  
City Population ◽  
Different Types ◽  
Acid Character

<p class="Mabstract">The Moroccan diet is the Mediterranean characterized by a nutritional model that has remained constant in time and space (main ingredients are olive oil, cereals, fresh or dried fruits, and vegetables...). This study's main objective is to reveal the eating habits, the food combination, and the different types of meals that the Kenitra city population is most adopted through a questionnaire filled in by the participants. An investigation is being carried out from June to August 2018 in Kenitra city. This gives information about the composition of meals taken in Moroccan households. The study covered a sample of 510 homes. Analysis of the results showed that the consumption of raw vegetables in salads and an acidic character was the most frequent. It represents 41.2% of the rest of the salads consumed by the target population. The inclusion in the salad of ingredients with an acid-base character takes second place with a percentage of 19.6%. Salads with essential characteristics took third place, with 17.1%.</p><p class="Mabstract">Regarding the consumption of salads in which specific ingredients are cooked. It emerges from the results that salads with an acid character are the most consumed. The percentage obtained in this case is 54.1%. The salads with acid-base characteristics are consumed by the respondents, with a ratio of 26.5% to occupy the second position. Salads of this category having a primary character are eaten with a frequency of 19.4%. The combinations are characterized by their acidity, which can cause serious digestive problems for the consumer.</p>

Virome and Inflammasomes, a Finely Tuned Balance with Important Consequences for the Host Health

2019 ◽  
Vol 26 (6) ◽  
pp. 1027-1044 ◽  
Author(s):  
Giulia Freer ◽  
Fabrizio Maggi ◽  
Mauro Pistello
Keyword(s):  
Immune System ◽  
Human Beings ◽  
Review Of The Literature ◽  
Adaptive Immune ◽  
Downstream Effects ◽  
Host Health ◽  
Inflammatory Processes ◽  
Human Immune ◽  
Immune Defences

Background:The virome is a network of viruses normally inhabiting humans. It forms a conspicuous portion of the so-called microbiome, once generically referred to as resident flora. Indeed, viruses infecting humans without leading to clinical disease are increasingly recognized as part of the microbiome and have an impact on the development of our immune system. In addition, they activate inflammasomes, multiprotein complexes that assemble in cells and that are responsible for the downstream effects of sensing pathogens.Objective:This review aims at summarizing the evidence on the role of the virome in modulating inflammation and emphasizes evidence for Anelloviruses as useful molecular markers to monitor inflammatory processes and immune system competence.Method:We carried out a review of the literature published in the last 5 years and summarized older literature to take into account ground-breaking discoveries concerning inflammasome assembly and virome.Results:A massive amount of data recently emerging demonstrate that the microbiome closely reflects what we eat, and many other unexpected variables. Composition, location, and amount of the microbiome have an impact on innate and adaptive immune defences. Viruses making up the virome contribute to shaping the immune system. Anelloviruses, the best known of such viruses, are present in most human beings, persistently without causing apparent disease. Depending on their interplay with such viruses, inflammasomes instruct host defences to tolerate or forfeit a specific microorganism.Conclusion:The virome plays an important role in shaping human immune defences and contributes to inflammatory processes by quenching or increasing them.

The Immune System Regulation in Sepsis: From Innate to Adaptive

2019 ◽  
Vol 20 (8) ◽  
pp. 799-816 ◽  
Author(s):  
Yue Qiu ◽  
Guo-wei Tu ◽  
Min-jie Ju ◽  
Cheng Yang ◽  
Zhe Luo
Keyword(s):  
Clinical Trials ◽  
Immune System ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Immune Cells ◽  
Current Knowledge ◽  
Systemic Inflammatory Response ◽  
Immune System Regulation

Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of a systemic inflammatory response syndrome. The activation and regulation of the immune system play a key role in the initiation, development and prognosis of sepsis. Due to the different periods of sepsis when the objects investigated were incorporated, clinical trials often exhibit negative or even contrary results. Thus, in this review we aim to sort out the current knowledge in how immune cells play a role during sepsis.

scholarly journals The immune response of T cells and therapeutic targets related to regulating the levels of T helper cells after ischaemic stroke

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Tian-Yu Lei ◽  
Ying-Ze Ye ◽  
Xi-Qun Zhu ◽  
Daniel Smerin ◽  
Li-Juan Gu ◽  
...  
Keyword(s):  
Immune Response ◽  
T Cells ◽  
Immune System ◽  
Immune Responses ◽  
Ischaemic Stroke ◽  
Immune Cells ◽  
Tissue Injury ◽  
Recovery Period ◽  
Vital Functions ◽  
Anti Inflammatory

AbstractThrough considerable effort in research and clinical studies, the immune system has been identified as a participant in the onset and progression of brain injury after ischaemic stroke. Due to the involvement of all types of immune cells, the roles of the immune system in stroke pathology and associated effects are complicated. Past research concentrated on the functions of monocytes and neutrophils in the pathogenesis of ischaemic stroke and tried to demonstrate the mechanisms of tissue injury and protection involving these immune cells. Within the past several years, an increasing number of studies have elucidated the vital functions of T cells in the innate and adaptive immune responses in both the acute and chronic phases of ischaemic stroke. Recently, the phenotypes of T cells with proinflammatory or anti-inflammatory function have been demonstrated in detail. T cells with distinctive phenotypes can also influence cerebral inflammation through various pathways, such as regulating the immune response, interacting with brain-resident immune cells and modulating neurogenesis and angiogenesis during different phases following stroke. In view of the limited treatment options available following stroke other than tissue plasminogen activator therapy, understanding the function of immune responses, especially T cell responses, in the post-stroke recovery period can provide a new therapeutic direction. Here, we discuss the different functions and temporal evolution of T cells with different phenotypes during the acute and chronic phases of ischaemic stroke. We suggest that modulating the balance between the proinflammatory and anti-inflammatory functions of T cells with distinct phenotypes may become a potential therapeutic approach that reduces the mortality and improves the functional outcomes and prognosis of patients suffering from ischaemic stroke.

scholarly journals Targeting Transforming Growth Factor β to Enhance Cancer Immunotherapy

2006 ◽  
Vol 13 (4) ◽  
pp. 141-143 ◽  
Author(s):  
T. Hahn ◽  
Emmanuel Akporiaye
Keyword(s):  
Immune System ◽  
Growth Factor ◽  
Cancer Immunotherapy ◽  
Immune Cells ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Human Tumours

Human tumours have evolved intricate mechanisms to evade the immune system, either by avoiding recognition or by inhibiting and eliminating immune cells. [...]

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