Research on Electrospinning Process of Pullulan Nanofibers

2012 ◽  
Vol 268-270 ◽  
pp. 198-201 ◽  
Author(s):  
Xiao Bin Sun ◽  
D. Jia ◽  
Wei Min Kang ◽  
Bo Wen Cheng ◽  
Ya Bin Li
Keyword(s):  
Flow Rate ◽  
Applied Voltage ◽  
Great Influence ◽  
Solution Concentration ◽  
Electrospinning Process ◽  
Diameter Distribution ◽  
Optimal Parameters ◽  
Redistilled Water ◽  
Water As Solvent

A kind of pullulan biopolymer nanofibers with diameter of 100～700nm were obtained using redistilled water as solvent through electrospinning technology in this paper. The effects of the spinning solution concentration, applied voltage, flow rate and capillary–screen distance on morphology and diameter distribution of pullulan nanofiber were studied by SEM. The results show that, different parameters had great influence on nanofibers’ morphology and diameter. The optimal parameters of pullulan nanofibers electrospinning were: 22wt.% spinning solution concentration, 31 kV voltage, 20 cm capillary–screen distance and 0.5ml/h flow rate.

Morphology of Biodegradable Poly(hexamethylene Adipate)(PHMA) Nanofibers Prepared by Electrospinning

2009 ◽  
Vol 87-88 ◽  
pp. 555-560
Author(s):  
Wei Min Kang ◽  
Bo Wen Cheng ◽  
Quan Xiang Li ◽  
Xu Pin Zhuang
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Flow Rate ◽  
Applied Voltage ◽  
Mixed Solvent ◽  
Solution Concentration ◽  
Electrospinning Process ◽  
Solvent Ratio ◽  
Biodegradable Poly ◽  
Scanning Electron

A kind of novel biodegradable poly(hexamethylene adipate) (PHMA) nanofibers with diameter of 100～700nm using a mixed solvent of 1,2-dichloroethane (DCE ) and trifluoroacetic acid (TFA) were obtained by electrospinning process in this paper. The morphology of electropun PHMA nanofibers were investigated by scanning electron microscopy (SEM). The results showed that the morphology, diameter and uniformity of the fibers were influenced by solvent ratio, solution concentration, applied voltage, capillary–screen distance and flow rate greatly. The finer and uniform nanofibers were electrospun from a mixed solvent of DCE and TFA with ratio of 70/30(w/w).

Effect of Electrospinning Parameters Setting towards Fiber Diameter

2013 ◽  
Vol 845 ◽  
pp. 985-988 ◽  
Author(s):  
N.H.A. Ngadiman ◽  
M.Y. Noordin ◽  
Ani Idris ◽  
Denni Kurniawan
Keyword(s):  
Flow Rate ◽  
Applied Voltage ◽  
Fiber Diameter ◽  
Volume Flow Rate ◽  
Electrospinning Process ◽  
Volume Flow ◽  
Fiber Volume ◽  
Nanofiber Diameter ◽  
New Process

Fabrication of nanofibers using electrospinning has recently attracted much attention for various applications due to its simplicity. Electrospinning has the ability to produce nanofibers within 100-500 nm. Some applications require certain fiber diameter. As a relatively new process, there are many electrospinning parameters that are believed to influence the nanofibers diameter. The purpose of this review is to identify and discuss the effect of some of those parameters, i.e. concentration, spinning distance, and applied voltage, and volume flow rate, to the nanofiber diameter during electrospinning process. It was concluded that fiber volume flow rate is proportional to fiber diameter while there is no agreement in reports on other parameters.

Basic Study for Micro Pump Using Electroosmotic Flow

2003 ◽  
Author(s):  
Tamio Fujiwara ◽  
Akinori Kamiya ◽  
Osami Kitoh ◽  
Tatsuo Ushijima
Keyword(s):  
Pressure Gradient ◽  
Flow Rate ◽  
Applied Voltage ◽  
Electroosmotic Flow ◽  
Great Influence ◽  
Smoluchowski Equation ◽  
Flow Meter ◽  
Flow Rates ◽  
Micro Pump ◽  
Gap Width

The characteristic features of electroosmotic flow have been studied to obtain important information for applying the flow to a micro pump as a driving device. Here, an electroosmotic flow of water was generated in a donut channel constructed by a gap between two parallel donut-shaped glass plates. The flow rate was measured in relation to the applied voltage, the gap width of the channel, the pressure gradient and the properties of the fluid. The experimental results were compared with a theoretical equation of electroosmosis, the Helmholtz-Smoluchowski equation, which predicts that the electroosmotic flow rate is proportional to the applied voltage as well as to the gap width. The Electroosmotic flow rate increased linearly with the applied voltage. however, there appeared some particular voltage ranges of nonlinear relation unlike the Helmholtz-Smoluchowski equation. The water properties (the conductivity and the kinds of impurities included) had a great influence on the electroosmotic flow rate characteristics including the degree of non-linearity and even the flow direction. The cause of these phenomena has not been clarified. It is conjectured that the zeta potential of the glass-water interface was altered by the applied electric field. It is confirmed that the electroosmotic flow rate is proportional to the gap size of the channel. When a pressure gradient existed in the direction of the electroosmotic flow, the total flow rate was given as a sum of the flow rates of the electroosmotic and Poiseuille flows. These findings provide important information for micro pumps. For measuring the electroosmotic flow rate, we developed a micro flow meter consisting of a capillary and two fine wires. This flow meter makes it possible to measure a flow rate the order of 1×10−3 mm3/sec (= 1 nl/sec) and has a potential ability to measure even much smaller flow rates.

Multi-Bubble Electrospinning of Nanofibers

2013 ◽  
Vol 843 ◽  
pp. 26-33
Author(s):  
Xue Feng Sun ◽  
Yong Liu ◽  
Jian Liu ◽  
Rui Wang ◽  
Yan Li Hu
Keyword(s):  
Applied Voltage ◽  
Large Scale ◽  
Solution Concentration ◽  
Processing Parameters ◽  
Mutual Interference ◽  
Electrospinning Process ◽  
Scale Production ◽  
Large Scale Production ◽  
Theoretical Investigations ◽  
Multiple Bubbles

Multi-bubble electrospinning is considered as one of efficient techniques which have potential for large scale production of nanofibers. However, there is a lack of published research to better understand the formation of bubbles and the mutual interference among these bubbles. In this paper, the formation methods of multiple bubbles on the free liquid surface were examined to determine which ones performed relatively well. The influence of solution concentration, applied voltage, gas pressure, liquid length and the shape of electrode on the process and morphology of nanofibers were also investigated. The results showed that multiple gas tubes in the solution was the best choice to produce stable multiple bubbles though the number of bubbles was less than that obtained by the other methods. Some important processing parameters, such as solution concentration, applied voltage and the shape of electrode, had an important influence on the morphologies of nanofibers. Finally, both experimental and theoretical investigations in this process proved that the mutual interference among bubbles existed during multi-bubble electrospinning process.

Preparation of Chitosan based Nanofibers: Optimization and Modeling

2016 ◽  
Vol 14 (1) ◽  
pp. 283-288 ◽  
Author(s):  
K. Thirugnanasambandham ◽  
V. Sivakumar
Keyword(s):  
Polymer Solution ◽  
Response Surface ◽  
Applied Voltage ◽  
Solution Concentration ◽  
Electrospinning Process ◽  
Interactive Effects ◽  
Optimum Process ◽  
Process Conditions ◽  
Good Correspondence ◽  
Nanofiber Diameter

AbstractThe main objective of the present study is to prepare a chitosan based nanofiber and model the electrospinning process using response surface methodology (RSM). The electrospinning parameters such as collector distance, polymer solution concentration and applied voltage were optimized by using three-variable-three-level Box–Behnken design (BBD). Based on RSM analysis, second order polynomial equation was formed and it indicated good correspondence between experimental and predicted values. 3D response surface plots were used to study the individual and interactive effects of process variables on chitosan based nanofiber diameter. The optimum process conditions for the minimum chitosan based nanofiber diameter (0.3 µm) were found to be collector distance of 12 cm, polymer solution concentration of 25% and applied voltage of 6 kV.

Development of Electrospun Shellac and Hydroxypropyl Cellulose Blended Nanofibers for Drug Carrier Application

2020 ◽  
Vol 859 ◽  
pp. 239-243
Author(s):  
Nawinda Chinatangkul ◽  
Sirikarn Pengon ◽  
Suchada Piriyaprasarth ◽  
Chutima Limmatvapirat ◽  
Sontaya Limmatvapirat
Keyword(s):  
Drug Delivery ◽  
Antimicrobial Agent ◽  
Flow Rate ◽  
Applied Voltage ◽  
Infusion Rate ◽  
Fiber Diameter ◽  
Electrospun Fiber ◽  
Drug Carrier ◽  
Hydroxypropyl Cellulose ◽  
Electrospinning Process

The aim of this study was to develop the electrospun shellac (SHL) and hydroxypropyl cellulose (HPC) blended nanofibers for drug carrier application. The effects of polymer solution and electrospinning parameters, including SHL-HPC ratio, HPC concentration, applied voltage and flow rate, on the appearance of fibers were investigated. Based on the results, electrospun fiber was not obtained when a solution of HPC alone was employed. However, the fibers would be obviously fabricated as SHL was added to the HPC solution. An increase in the SHL ratio in SHL-HPC blended solution could accordingly lead to a remarkable enhance in the fiber diameter. In addition, the continuous nanofibers with less beads were gradually formulated when the HPC concentration was increased. The electrospinning parameters seemed to be significant. The elevation of infusion rate from 0.5 to 1 mL/h would contribute to the preparation of thick fibers with the diameters enlarging from 666.9 to 843.5 nm. With the applied voltage increasing from 15 to 30 kV during the electrospinning process, the fabrication of small nanofibers with the diameters reducing from 843.5 to 741.6 nm would be conducted. In this study, monolaurin (ML), a broad antimicrobial agent, was encapsulated into the SHL-HPC carrier for the purpose of drug delivery application. Regarding the result, the loaded concentration of ML could not be enhanced by introducing HPC to the SHL fibers.

scholarly journals Effect of parameters on the morphology and fibre diameters of edible electrospun chitosan-cellulose acetate-gelatin hybrid nanofibres

2018 ◽  
Vol 192 ◽  
pp. 03038
Author(s):  
Jaruayporn Somsap ◽  
Kobsak Kanjanapongkul ◽  
Racha Tepsorn
Keyword(s):  
Cellulose Acetate ◽  
Flow Rate ◽  
Applied Voltage ◽  
Acetic Acid Solution ◽  
Volume Ratio ◽  
Solution Concentration ◽  
Processing Parameters ◽  
Gelatin Solution ◽  
Electrospun Nanofibres ◽  
Scanning Electron

Electrospinning is the favorite process to fabricate fibres with diameter in the range nanoscale through the action of electric field. In this study, 3-7% chitosan, 18.0% cellulose acetate and 30.0% gelatin solution in aqueous 80% acetic acid solution were blended at the volume ratio of 4:1:5 have been successfully electrospun. The effect of processing parameters and the concentration of the polymer solution on the morphology and diameter of electrospun were investigated. The morphology and diameter of electrospun fibres were observed by scanning electron microscope. The diameters of chitosan-cellulose acetate-gelatin nanofibres ranging from 78.94 to 421.05 nm. The results showed that the fibre diameters increased when the solution concentration and flow rate were increased, whereas the fibre diameters decreased when the applied voltage and distance between tip to collector were increased. The conditions of the solution concentration 18.8 %wt, applied voltage at 23 kV, flow rate at 11.67 μL/min and collector distance at 10 cm were selected to prepares the desirable electrospun nanofibres for applications and the further research.

scholarly journals Controlled Morphology of Porous Polyvinyl Butyral Nanofibers

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Daniela Lubasova ◽  
Lenka Martinova
Keyword(s):  
Applied Voltage ◽  
High Efficiency ◽  
Polymer Concentration ◽  
Polyvinyl Butyral ◽  
Solution Concentration ◽  
Solvent Mixture ◽  
Electrospinning Process ◽  
Filter Materials ◽  
One Step ◽  
Poor Solvent

A simple and effective method for the fabrication of porous nanofibers based on the solvent evaporation methods in one-step electrospinning process from the commercial polyvinyl butyral (PVB) is presented. The obtained nanofibers are prevalently amorphous with diameters ranging from 150 to 4350 nm and specific surface area of approximately 2–20 m2/g. Pore size with irregular shape of the porous PVB fibers ranged approximately from 50 to 200 nm. The effects of polymer solution concentration, composition of the solvents mixture, and applied voltage on fiber diameter and morphology were investigated. The theoretical approach for the choice of poor and good solvents for PVB was explained by the application Hansen solubility parameter (HSP) and two-dimensional graph. Three basic conditions for the production of porous PVB nanofibers were defined: (i) application of good/poor solvent mixture for spinning solution, (ii) differences of the evaporation rate between good/poor solvent, and (iii) correct ratios of good/poor solvent (v/v). The diameter of prepared porous PVB fibers decreased as the polymer concentration was lowered and with higher applied voltage. These nanofiber sheets with porous PVB fibers could be a good candidate for high-efficiency filter materials in comparison to smooth fibers without pores.

scholarly journals Effect of Electrospinning Parameters on the Fiber Diameter and Morphology of PLGA Nanofibers

2021 ◽  
pp. 1-7
Author(s):  
Yuanyuan Duan ◽  
Lohitha Kalluri ◽  
Megha Satpathy ◽  
Yuanyuan Duan
Keyword(s):  
Bone Regeneration ◽  
Flow Rate ◽  
Applied Voltage ◽  
Fiber Diameter ◽  
Solution Concentration ◽  
Electrospun Fibers ◽  
High Porosity ◽  
The Mean ◽  
Nanoscale Fibers ◽  
One Way Anova

Background: Poly lactic-co-glycolic acid (PLGA) has been widely investigated for various biomedical applications, such as craniofacial bone regeneration, wound dressing and tissue engineering. Electrospinning is a versatile technology used to produce micro/nanoscale fibers with large specific surface area and high porosity. Purpose: The aim of the current study is to prepare PLGA nanofibers using electrospinning for guided tissue regeneration/guided bone regeneration applications. The objective of this study is to determine the appropriate electrospinning parameters such as applied voltage, flow rate, spinneret-collector distance and polymer solution concentration for preparation of PLGA fibrous membrane and their effect on the mean fiber diameter of the electrospun fibers. Method: PLGA pellets were dissolved in Hexafluoroisopropanol (HFIP) in various concentrations overnight using a bench rocker. The resulting PLGA solution was then loaded into a syringe and electrospinning was done by maintaining the other parameters constant. Similarly, various fibrous mats were collected by altering the specific electrospinning parameter inputs such as applied voltage, flow rate and spinneret-collector distance. The morphology of the fibrous mats was characterized using Scanning Electron Microscope. The mean fiber diameter was assessed using ImageJ software and the results were compared using one-way ANOVA. Results: We obtained bead-free uniform fibers with various tested solution concentrations. One-way ANOVA analysis demonstrated significant variation in mean fiber diameter of the electrospun fibers with altering applied voltage, solution concentration, flow rate and spinneret-collector distance. Conclusion: The above-mentioned electrospinning parameters and solution concentration influence the mean fiber diameter of electrospun PLGA nanofibers.

Sign in / Sign up

Export Citation Format

Share Document