Conversion of Strontium Hydroxyapatite Nanopowders to Porous Scaffolds for Bone Implant Application

2014 ◽  
Vol 607 ◽  
pp. 3-6
Author(s):  
Che Murad Mardziah ◽  
Iis Sopyan ◽  
Koay Mei Hyie ◽  
N.R. Nik Roselina
Keyword(s):  
Compressive Strength ◽  
Cancellous Bone ◽  
Compression Test ◽  
Ambient Air ◽  
Porous Scaffolds ◽  
Distilled Water ◽  
Bone Implant ◽  
Morphological Evaluation ◽  
Dispersing Agent ◽  
Xrd Patterns

The fabrication of Sr hydroxyapatite (HA) porous scaffolds was done by using polymeric sponge method. To prepare the porous samples, the synthesized SrHA nanopowders were mixed with distilled water and appropriate amount of dispersing agent followed by drying in the ambient air and sintering at 1300°C. The compressive strength of the materials was strongly influenced by the porosity, while there was almost no dependence on the crystallinity of the powders since XRD patterns showed high crystallinity of HA phase for all porous samples. Morphological evaluation by FESEM revealed that the SrHA scaffolds were characterized by macro-micro interconnected porosity, which replicates the morphology of the cancellous bone. Compression test on the porous scaffolds demonstrated that doping 10 mol% of strontium in HA has increased the compressive strength by a factor of two compared to the undoped HA with 1.81±0.26 MPa at 41% porosity.

Fabrication and Characterization of Strontium-Doped Hydroxyapatite Bioceramics Scaffolds for Bone Implant Application: A Preliminary Study

2010 ◽  
Vol 93-94 ◽  
pp. 401-404 ◽  
Author(s):  
M.C. Murad ◽  
Iis Sopyan ◽  
C. Rohaida ◽  
Z. Ahmad ◽  
M. Reusmaazran
Keyword(s):  
Sol Gel ◽  
Ambient Air ◽  
Porous Scaffolds ◽  
Chemical Compositions ◽  
Bone Implant ◽  
Porous Bodies ◽  
Morphological Evaluation ◽  
Dispersing Agent ◽  
Xrd Patterns

In this study, strontium doped hydroxyapatite (SrHA) nanopowder was synthesized through a sol-gel method. Strontium concentration was varied from 0 to 15 mol%. The obtained gel was then dried and subsequently subjected to 900 °C calcination. SrHA porous bodies were fabricated by using polymeric sponge method with different chemical compositions (0, 2 and 10 mol% SrHA). To prepare the porous samples, the synthesized SrHA powders was mixed with distilled water and appropriate amount of dispersing agent followed by drying in the ambient air for 72 hours. The dried impregnated sponges were then sintered at 1300°C for 3 hours. The XRD patterns showed high crystallinity of HA phase only for all porous samples. Morphological evaluation by FESEM measurement revealed that the SrHA scaffolds were characterized by a uniform distribution of interconnected pores (200-800 µm). Compression test on the porous scaffolds revealed that doping 10 mol% of strontium in HA has increased the compressive strength compared to the undoped HA.

Fabrication of Porous Ceramic Scaffolds via Polymeric Sponge Method Using Sol-Gel Derived Strontium Doped Hydroxyapatite

2011 ◽  
Vol 117-119 ◽  
pp. 829-832 ◽  
Author(s):  
I. Sopyan ◽  
C.M. Mardziah ◽  
Ramesh Singh
Keyword(s):  
Cell Attachment ◽  
Calcium Phosphates ◽  
Porous Ceramic ◽  
Sol Gel ◽  
Ambient Air ◽  
Porous Scaffolds ◽  
High Porosity ◽  
Sintering Process ◽  
Morphological Evaluation ◽  
Dispersing Agent

Recently, development of porous calcium phosphates ceramics has raised considerable interest. A porous structure promotes cell attachment, proliferation and provides pathways for biofluids. Therefore, a high porosity with interconnected pore structure generally favors tissue regeneration. In this work, replication of 0, 2, 5, 10 and 15% SrHA (strontium-doped hydroxyapatite) porous scaffolds via polymeric sponge method has been employed using the sol-gel derived SrHA powders. To prepare the porous samples, the synthesized SrHA powders were mixed with distilled water and dispersing agent followed by drying in the ambient air and specific sintering process. Morphological evaluation by FESEM measurement revealed that the SrHA scaffolds were characterized by macro-micro interconnected porosity, which replicates the morphology of the cancellous bone. Compression test on the porous scaffolds revealed that doping 10 mol% of strontium in HA has increased the compressive strength by a factor of two compared to the undoped HA with 1.81±0.26 MPa at 41% porosity.

Effect of Slurry Preparation on Physical Properties of Porous Hydroxyapatite Prepared via Polymeric Sponge Method

2008 ◽  
Vol 47-50 ◽  
pp. 932-935 ◽  
Author(s):  
Iis Sopyan ◽  
J. Kaur ◽  
A.R. Toibah ◽  
Mohd Hamdi Bin Abdul Shukor ◽  
Ramesh Singh
Keyword(s):  
Compressive Strength ◽  
Cancellous Bone ◽  
Sintering Process ◽  
Porous Hydroxyapatite ◽  
Porous Bodies ◽  
Hydroxyapatite Powder ◽  
Dispersing Agent ◽  
Human Cancellous Bone ◽  
Stirring Time ◽  
Slurry Preparation

Hydroxyapatite porous materials for cancellous bone applications were prepared via polymeric sponge method. Suspensions of the nanostructured hydroxyapatite powders were prepared via stirring of the mixture of hydroxyapatite powder, water, and dispersing agent. The stirring time was adjusted at 4 and 20 hours. After soaking cellulosic sponges into the suspension, the sponges were dried and then subjected to heat-treatment at 600°C, followed by sintering at 1250°C for 1 h. No additional phases were identified in the sintered porous hydroxyapatite. This result showed that the sintering process did not alter the hydroxyapatite phase composition. The study found that the apparent density of the porous bodies varied from 1.69 g/cm3 to 2.03 g/cm3 with 35.6 – 46.2 % porosities and 100-500 microns macropore size depending on the composition of slurry and the stirring time. Longer stirring time resulted in the breakdown of HA agglomerates and the slurry obtained tends to be more homogeneous, leading to higher density and better compressive strength of the sintered porous bodies. The measurement of compressive strength provided the values of 4.3 MPa and 10 MPa for 4 h and 20 h stirring time, which is in the range of mechanical strength of human cancellous bone.

Size Effect on Mechanical Properties of LVL

2014 ◽  
Vol 887-888 ◽  
pp. 824-829
Author(s):  
Qing Fang Lv ◽  
Ji Hong Qin ◽  
Ran Zhu
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Compressive Strength ◽  
Size Effect ◽  
Tensile Test ◽  
Compression Test ◽  
Test Results ◽  
Laminated Veneer Lumber ◽  
Object Of Study ◽  
The Relationship

Laminated veneer lumber is taken as an object of study, and use LVL specimens of different sizes for compression test and tensile test. The goal of the experiment is to investigate the size effect on compressive strength and tensile strength as well as the influence of the secondary glued laminated face, which appears in the secondary molding processes. The results show that both compressive strength and tensile strength have the size effect apparently and the existence of the secondary glued laminated face lower the compressive strength of LVL specimens. Afterwards, the relationship between compressive strength and volume along with tensile strength and area are obtained by the test results.

scholarly journals Pemanfaatan Lumpur Lapindo sebagai Bahan Baku Pembuatan Genteng Keramik dengan Variasi Suhu Pembakaran

Eksergi ◽  
2015 ◽  
Vol 12 (1) ◽  
pp. 08
Author(s):  
Wasir Nuri ◽  
Dyah Tri Retno
Keyword(s):  
Grain Size ◽  
Compressive Strength ◽  
Water Absorption ◽  
Combustion Temperature ◽  
Ambient Air ◽  
Industrial Area ◽  
Type I ◽  
Flooded Rice ◽  
Roof Tile ◽  
Silica Oxide

Lapindo mudflow issued a very large volume of mud. The mud flooded rice fields, residential and industrial area to date has not been stopped but the mud bursts untapped yet. Therefore, attempted use Lapindo mud very much it to be made tile. Sludge containing 55.4% silica oxide, alumina 16.1% and 8.9% iron with the composition of the possibility of mud can be created tile roof. Dried mud that has been mashed into the grain size of 80 mesh, then water added until plastic. Mud that has plastic printed with size 6 x 3 x 3 cm and then dried using ambient air. After the dried samples were burned using a furnace at temperatures varying from 500 to 900oC, after chilling the samples tested compressive strength, fracture modulus and water absorption. The results showed that the higher the combustion temperature obtained greater compressive strength and less water absorption. Most compressive strength is 142 kg/cm2and smallest water absorption is 0.06 g/cm2at a temperature of 900oC. At combustion temperatures of 500 to 700oC fracture modulus down from 72.78 to 41.81 kg/cm2 while at 700 to 900oC fracture modulus rose to 126.7 kg/cm2. The best results obtained on the combustion temperature at 800oC with fracture modulus 103.18 kg/cm2 and water absorption 0.08 g/cm2.   These results satisfy roof tile as type I according SII.0027 UDC-81. 666.74.

Effect of Curing Time and Sintering to the Properties of Geopolymer Mortars

2017 ◽  
Vol 888 ◽  
pp. 184-187
Author(s):  
Salwa Ismail ◽  
Mohammad Faizal Mohd Razali ◽  
Izwan Johari ◽  
Zainal Arifin Ahmad ◽  
Shah Rizal Kasim
Keyword(s):  
Compressive Strength ◽  
Fly Ash ◽  
Distilled Water ◽  
Curing Time ◽  
Pore Former ◽  
X Ray ◽  
Before And After ◽  
Naoh Solution ◽  
Added Water ◽  
Alkaline Activator

In this study, the geopolymer mortars were synthesized with fly ash (FA) and silica powder as aluminosilicate sources and a combination of sodium hydroxide (NaOH) solution, sodium silicate (Na2SiO3) solution and distilled water as alkaline activator. Commercial sago was used as a pore former in the mortars. The percentage of sago used were 10, 20 and 30 wt% of FA. The amount of added water used in each mixture was 5% by weight of FA, NaOH solution and Na2SiO3 solution. The formed geopolymer mortars were cured for 1, 3 and 7 days and sintered at 1000 °C. X-ray fluoresence (XRF) shown that FA contains higher amount of silica (SiO2) and alumina (Al2O3) which is important as aluminosilicate sources. The properties of the geopolymer mortars before and after sintered at 1000 °C have been investigated. The results show that geopolymer mortars with 10% of sago content with curing time of 7 days and sintered at 1000 °C give the highest compressive strength of 13.5 MPa.

scholarly journals Influence of high insertion torque on implant placement: an anisotropic bone stress analysis

2010 ◽  
Vol 21 (6) ◽  
pp. 508-514 ◽  
Author(s):  
Bruno Salles Sotto-Maior ◽  
Eduardo Passos Rocha ◽  
Erika Oliveira de Almeida ◽  
Amilcar Chagas Freitas-Júnior ◽  
Rodolfo Bruniera Anchieta ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Cancellous Bone ◽  
Maximum Principal Stress ◽  
Insertion Torque ◽  
Stress Concentrations ◽  
Bone Implant ◽  
Significance Level ◽  
Bone Stress ◽  
Implant Placement ◽  
Solid Works

The aim of this study was to evaluate the influence of the high values of insertion torques on the stress and strain distribution in cortical and cancellous bones. Based on tomography imaging, a representative mathematical model of a partial maxilla was built using Mimics 11.11 and Solid Works 2010 softwares. Six models were built and each of them received an implant with one of the following insertion torques: 30, 40, 50, 60, 70 or 80 Ncm on the external hexagon. The cortical and cancellous bones were considered anisotropic. The bone/implant interface was considered perfectly bonded. The numerical analysis was carried out using Ansys Workbench 10.0. The convergence of analysis (6%) drove the mesh refinement. Maximum principal stress (σmax) and maximum principal strain (εmax) were obtained for cortical and cancellous bones around to implant. Pearson's correlation test was used to determine the correlation between insertion torque and stress concentration in the periimplant bone tissue, considering the significance level at 5%. The increase in the insertion torque generated an increase in the σmax and εmax values for cortical and cancellous bone. The σmax was smaller for the cancellous bone, with greater stress variation among the insertion torques. The εmax was higher in the cancellous bone in comparison to the cortical bone. According to the methodology used and the limits of this study, it can be concluded that higher insertion torques increased tensile and compressive stress concentrations in the periimplant bone tissue.

scholarly journals Can osteophagia provide giraffes with phosphorus and calcium?

2008 ◽  
Vol 75 (1) ◽  
Author(s):  
I.P. Bredin ◽  
J.D. Skinner ◽  
G. Mitchell
Keyword(s):  
Cancellous Bone ◽  
Rumen Fluid ◽  
Artificial Saliva ◽  
Cervical Vertebrae ◽  
Distilled Water ◽  
Metacarpal Shaft ◽  
Observed Behaviour ◽  
Calcium And Phosphorus

The daily requirement for calcium and phosphorus by giraffes to sustain the growth and maintenance of their skeletons is large. The source of sufficient calcium is browse. The source of necessary phosphorus is obscure, but it could be osteophagia, a frequently observed behaviour in giraffes. We have assessed whether bone ingested as a result of osteophagia can be digested in the rumen. Bone samples from cancellous (cervical vertebrae) and dense bones (metacarpal shaft) were immersed in the rumens of five sheep, for a period of up to 30 days, and the effect compared to immersion in distilled water and in artificial saliva for 30 days. Distilled water had no effect on the bones. Dense bone samples were softened by exposure to the saliva and rumen fluid, but did not lose either calcium or phosphorus. In saliva and rumen fluid the cancellous bone samples also softened, and their mass and volume decreased as a result of exposure to saliva, but in neither fluid did they lose significant amounts of calcium and phosphorus. We conclude that although saliva and rumen fluid can soften ingested bones, there is an insignificant digestion of bones in the rumen.

Comparison of Porous Ti6Al4V Made by Sponge Replication and Directly 3D Fiber Deposition and Cancellous Bone

2007 ◽  
Vol 330-332 ◽  
pp. 999-1002 ◽  
Author(s):  
J.P. Li ◽  
J.R. Wijn ◽  
Clemens A. van Blitterswijk ◽  
K. de Groot
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Pore Structure ◽  
Cancellous Bone ◽  
Structure And Properties ◽  
Porous Ti ◽  
Fiber Deposition ◽  
Regular Open

The present investigation gives a comparison of the structure and properties of porous Ti6Al4V made by sponge replication (Sponge Ti) and directly 3D fiber deposition (D3DF Ti) and cancellous bone. Although the macrostructure of these two materials differs, their microstructure seems to be similar. Both scaffolds reveal an open pore structure, while D3DF Ti shows a fairly regular open pore structure, sponge Ti6Al4V exhibit an irregular open pore structure similar to that of cancellous bone. The mechanisms resulting in mechanical properties like stiffness or strength are, accordingly, different. The compressive strength and E’ modulus of Ti6Al4V scaffold are higher than that of cancellous bone,. The permeability results show both Ti6Al4V scaffolds are quite comparable with cancellous bone.

Preparation and Property of Waterborne Polyurethane Waterproofing Composites

2013 ◽  
Vol 477-478 ◽  
pp. 1184-1186
Author(s):  
Yan Ping Wang ◽  
Xiao Lei Su ◽  
Yong Sheng Tan ◽  
Kai Li Zhao ◽  
Yin Hu Qu
Keyword(s):  
Compressive Strength ◽  
Tensile Testing ◽  
Raw Materials ◽  
Testing Machine ◽  
Waterborne Polyurethane ◽  
Distilled Water ◽  
Tensile Testing Machine ◽  
Compression Performance

Waterborne polyurethane waterproofing composite has been prepared using polyurethane emulsion, cement, sand, and distilled water as raw materials, respectively. The compression performance of the samples has been determined by tensile testing machine. The microstructure of the samples has been observed by metallographic microscope. At the same time, the water resisting property of samples has been presented. The result shows that the surface of samples becomes the more smoothing with the increase ratio of cement to sand. The best compressive strength and water resisting property have been obtained when the weight of polyurethane emulsion to distilled water was 1:5 and the ratio of sand to cement was 2.1:1.

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