Resonance Frequency Change in Microcantilever-Based Sensor due to Humidity Variation

2013 ◽  
Vol 737 ◽  
pp. 176-182 ◽  
Author(s):  
Ratno Nuryadi ◽  
Arko Djajadi ◽  
Reyhan Adiel ◽  
Lia Aprilia ◽  
Nuning Aisah
Keyword(s):  
Environmental Monitoring ◽  
Resonance Frequency ◽  
Rapid Detection ◽  
High Sensitivity ◽  
Spring Constant ◽  
Dynamic Mode ◽  
Frequency Change ◽  
The Many

Microcantilever-based sensors have attracted interest in the last decade because of their small size, rapid detection and high sensitivity. This sensor can be applied in the many fields, i.e. physics, chemistry, biology, biochemistry, medical, and environment. In this paper, we describe microcantilever-based sensor for environmental monitoring, especially for a humidity detection. This sensor was operated in dynamic mode where a change in mass or spring constant of the microcantilever provides the resonance frequency change. Here, a change of humidity is detected by the resonance frequency and the amplitude changes. It is found that the increase in the humidity causes the decreasing the resonance frequency but increasing the amplitude. This result opens up the possibility of the humidity detection using microcantilever-based sensor.

Modeling of I-, T- and V-Shaped Microcantilevers for Environmental Monitoring

2013 ◽  
Vol 737 ◽  
pp. 119-125 ◽  
Author(s):  
Ratno Nuryadi
Keyword(s):  
Environmental Monitoring ◽  
Effective Mass ◽  
Spring Constant ◽  
Dynamic Mode ◽  
Sensor Sensitivity ◽  
Resonance Frequencies ◽  
Simulation Results

This paper describes a model of microcantilever to determine the optimal dimensions that can be used for environmental monitoring. Three types, which are usually used i.e., I-, T- and V-shaped microcantilevers, are considered. The microcantilevers work in dynamic mode in which their resonance frequencies depend on both spring constant and effective mass. It can be seen that the spring constant and effective mass of the microcantilever change when the structure is changed even the size is same. In consequent, the sensor sensitivity is also found to be different each other. The V-shaped microcantilever is more sensitive than I- and T-shaped ones. Moreover, the simulation results show that the microcantilever with sizes of length 10 µm, width 5 µm and thickness 100 nm is good enough to detect molecule gas with the mass of less than femtogram.

scholarly journals Magnetoelastic Coupling and Delta-E Effect in Magnetoelectric Torsion Mode Resonators

Sensors ◽  
2021 ◽  
Vol 21 (6) ◽  
pp. 2022
Author(s):  
Benjamin Spetzler ◽  
Elizaveta V. Golubeva ◽  
Ron-Marco Friedrich ◽  
Sebastian Zabel ◽  
Christine Kirchhof ◽  
...  
Keyword(s):  
Low Frequency ◽  
High Sensitivity ◽  
Element Model ◽  
Mode Number ◽  
Frequency Change ◽  
General Description ◽  
Resonance Modes ◽  
Field Sensor ◽  
Magnetic Sensitivity ◽  
Bending Modes

Magnetoelectric resonators have been studied for the detection of small amplitude and low frequency magnetic fields via the delta-E effect, mainly in fundamental bending or bulk resonance modes. Here, we present an experimental and theoretical investigation of magnetoelectric thin-film cantilevers that can be operated in bending modes (BMs) and torsion modes (TMs) as a magnetic field sensor. A magnetoelastic macrospin model is combined with an electromechanical finite element model and a general description of the delta-E effect of all stiffness tensor components Cij is derived. Simulations confirm quantitatively that the delta-E effect of the C66 component has the promising potential of significantly increasing the magnetic sensitivity and the maximum normalized frequency change ∆fr. However, the electrical excitation of TMs remains challenging and is found to significantly diminish the gain in sensitivity. Experiments reveal the dependency of the sensitivity and ∆fr of TMs on the mode number, which differs fundamentally from BMs and is well explained by our model. Because the contribution of C11 to the TMs increases with the mode number, the first-order TM yields the highest magnetic sensitivity. Overall, general insights are gained for the design of high-sensitivity delta-E effect sensors, as well as for frequency tunable devices based on the delta-E effect.

scholarly journals Small RNA-Sequencing: Approaches and Considerations for miRNA Analysis

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 964
Author(s):  
Sarka Benesova ◽  
Mikael Kubista ◽  
Lukas Valihrach
Keyword(s):  
Rna Sequencing ◽  
Small Rna ◽  
High Sensitivity ◽  
Small Rna Sequencing ◽  
Rna Seq ◽  
Liquid Biopsies ◽  
Comprehensive Overview ◽  
Rna Molecules ◽  
Novel Mirna ◽  
The Many

MicroRNAs (miRNAs) are a class of small RNA molecules that have an important regulatory role in multiple physiological and pathological processes. Their disease-specific profiles and presence in biofluids are properties that enable miRNAs to be employed as non-invasive biomarkers. In the past decades, several methods have been developed for miRNA analysis, including small RNA sequencing (RNA-seq). Small RNA-seq enables genome-wide profiling and analysis of known, as well as novel, miRNA variants. Moreover, its high sensitivity allows for profiling of low input samples such as liquid biopsies, which have now found applications in diagnostics and prognostics. Still, due to technical bias and the limited ability to capture the true miRNA representation, its potential remains unfulfilled. The introduction of many new small RNA-seq approaches that tried to minimize this bias, has led to the existence of the many small RNA-seq protocols seen today. Here, we review all current approaches to cDNA library construction used during the small RNA-seq workflow, with particular focus on their implementation in commercially available protocols. We provide an overview of each protocol and discuss their applicability. We also review recent benchmarking studies comparing each protocol’s performance and summarize the major conclusions that can be gathered from their usage. The result documents variable performance of the protocols and highlights their different applications in miRNA research. Taken together, our review provides a comprehensive overview of all the current small RNA-seq approaches, summarizes their strengths and weaknesses, and provides guidelines for their applications in miRNA research.

Stimulated electromagnetic shock radiation (SESR) in frequency-dispersive media

1977 ◽  
Vol 55 (17) ◽  
pp. 1499-1509 ◽  
Author(s):  
S. Schneider ◽  
R. Spitzer
Keyword(s):  
Resonance Frequency ◽  
Energy Levels ◽  
Stimulated Emission ◽  
Dispersive Media ◽  
Electron Trajectory ◽  
Frequency Change ◽  
Electromagnetic Shock ◽  
Frequency Changes ◽  
Shock Frequency ◽  
Shock Fronts

The interaction in a frequency-dispersive medium of a coherent electromagnetic wave with an electron moving faster than a critical (Mach) speed produces electromagnetic radiation with novel characteristics. Theory predicts emission of intense radiation in the form of shock fronts at specific angles from the electron trajectory. The shock fronts are correlated with specific frequencies shifted significantly from that of the incident wave. We have named this effect stimulated electromagnetic shock radiation (SESR). The shock frequencies depend dynamically on the populations of the energy levels that give rise to the medium resonances. A given shock frequency changes from below to above the resonance frequency of the medium with which it is associated as the populations of the two energy levels corresponding to this resonance frequency change from an equilibrium distribution to an inverted one. This dynamic resonance crossing points to the possibility of new synergisms between SESR emission and stimulated emission between discrete levels.

Gold Immunochromatography Assay - A Newly Rapid Detection Technique for Aquatic Products

2013 ◽  
Vol 690-693 ◽  
pp. 1449-1454
Author(s):  
Yuan Wang ◽  
Hui Juan Yu ◽  
Bei Lei Qian ◽  
You Qiong Cai ◽  
Dong Mei Huang ◽  
...  
Keyword(s):  
Rapid Detection ◽  
High Sensitivity ◽  
Detection Technique ◽  
Detection Methods ◽  
Future Perspectives ◽  
Auxiliary Equipment ◽  
Basic Principles ◽  
Aquatic Products ◽  
Immunological Detection

Gold immunochromatography assay (GICA) technique has the following characteristics: rapid and simple, high sensitivity, good specificity, no auxiliary equipment, ease of interpreting results, and satisfactory stability. The technique has become one of the most rapid and sensitive immunological detection methods, which is widely used in medical, biological and other fields. The article focuses on the basic principles and technical characteristics of GICA, and briefly describes the applications and future perspectives in the rapid detection of aquatic products.

New Perspectives for SARS-CoV-2 Rapid Detection

Coronaviruses ◽  
2021 ◽  
Vol 02 ◽  
Author(s):  
Latifa Khattabi ◽  
Mustapha Mounir Bouhenna ◽  
Feriel Sellam
Keyword(s):  
Rapid Detection ◽  
High Sensitivity ◽  
The Other ◽  
Host Cells ◽  
Rt Pcr ◽  
Human Immune System ◽  
Virus Attachment ◽  
Testing Procedures ◽  
Diagnostic Kits ◽  
Human Immune

: The present paper elucidates the conceivable application of two key molecules in SARS-CoV-2 detection of suspected infected persons. These molecules were selected from the basis of ACE-2 and S protein strong interaction that allows virus attachment to its host cells, on the other hand specific immunocompetant effectors generated by human immune system during the infection. Several testing procedures are already used to diagnose SARS-CoV-2 infection, particularly RT-PCR technique. ELISA and LFIA are possible assays for the employment of shACE-2/ hAc-anti-S (the molecules of interest) as the main agents of the test and confer a dual principal functions (capture and detection). The future diagnostic kits involving shACE-2 and hAc-anti-S will have the particularity of high sensitivity and rapid detection in addition to its advantage of relatively easy conception. It could be largely considered as a technical advanced kits in regards to the current SARS-CoV-2 diagnostic immunoassays.

A Numerical Approach of Estimating Dental Implant Healing Process Using Resonance Frequency Analysis (RFA)

2011 ◽  
Author(s):  
Reza Harirforoush ◽  
Siamak Arzanpour
Keyword(s):  
Resonance Frequency ◽  
Dental Implant ◽  
Frequency Analysis ◽  
Healing Process ◽  
Primary Stability ◽  
High Sensitivity ◽  
Titanium Implant ◽  
Resonance Frequency Analysis ◽  
Early Assessment ◽  
Bone Interface

This paper investigates primary stability of dental implant that indicates the process of bone-implant integration. This integration is known to happen at the boundary of the bone and dental implant contact surface. The resonance frequency of dental implant is used as the parameter for this investigation due to its high sensitivity to boundary condition variations. In this study, resonance frequency analysis (RFA) of the jaw-implant structure is carried out using finite element modeling. The FEM analyses are conducted in ANSYS modal analysis simulation environment. The FEM model of the structure includes titanium implant, Cancellous and cortical bone. Different implant-bone interface conditions are studied for this investigation. Various boundary conditions were studied to identify natural frequencies of jaw-implant structure. Our analysis shows that the resonance frequency of the implant increases during the healing period and reaches a plateau when the implant-bone interface was fully integrated. The results show that RFA could be suggested as a non-invasive, reliable and accurate diagnostic method for early assessment of the healing stages.

Rapid detection and enumeration of total bacteria in drinking water and tea beverages using a laboratory-built high-sensitivity flow cytometer

2015 ◽  
Vol 7 (7) ◽  
pp. 3072-3079 ◽  
Author(s):  
Muxin Yu ◽  
Lina Wu ◽  
Tianxun Huang ◽  
Shuo Wang ◽  
Xiaomei Yan
Keyword(s):  
Drinking Water ◽  
Rapid Detection ◽  
High Sensitivity ◽  
Flow Cytometer ◽  
Total Bacteria

This paper describes a method for the rapid detection and enumeration of total bacteria in drinking water and tea beverages.

scholarly journals Organic Molecule Detection Based on SERS in Microfluidics

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Xin Zhang ◽  
Haiyan Zhang ◽  
Sheng Yan ◽  
Zugang Zeng ◽  
Anshou Huang ◽  
...  
Keyword(s):  
Environmental Monitoring ◽  
Ag Nanoparticles ◽  
Organic Molecule ◽  
Organic Molecules ◽  
Chemical Reduction ◽  
Fdtd Method ◽  
Great Influence ◽  
High Sensitivity ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate

AbstractSensitive in situ detection of organic molecules is highly demanded in environmental monitoring. In this work, the surface enhanced Raman spectroscopy (SERS) is adopted in microfluidics to detect the organic molecules with high accuracy and high sensitivity. Here the SERS substrate in microchannel consists of Ag nanoparticles synthesized by chemical reduction. The data indicates the fabrication conditions have great influence on the sizes and distributions of Ag nanoparticles, which play an important role on the SERS enhancement. This result is further confirmed by the simulation of electromagnetic field distributions based on finite difference time domain (FDTD) method. Furthermore, the SERS spectra of organic molecule (methylene blue) obtained in this plasmonic microfluidic system exhibit good reproducibility with high sensitivity. By a combination of SERS and microfluidics, our work not only explores the research field of plasmonics but also has broad application prospects in environmental monitoring.

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