scholarly journals Prevalence of atherosclerosis risk factors in Egyptian patients with acute coronary syndrome: final data of the nationwide cross-sectional ‘CardioRisk’ project

2021 ◽  
Vol 11 (2) ◽  
Author(s):  
Ashraf Reda ◽  
Ahmed Bendary ◽  
Atef Elbahry ◽  
Elsayed Farag ◽  
Tamer Mostafa ◽  
...  

Background: Little are known about the prevalence of atherosclerosis risk factors in Egyptian patients with acute coronary syndromes (ACS). Objective: Describe the prevalence of these risk factors with focus on gender-specific data and patients with premature presentation. Methods: From November 2015 to August 2018, data were collected from 3224 patients with ACS in 30 coronary care centers covering 11 governorates across Egypt, with focus premature ACS. Results: The vast majority were males (74%) and the most prevalent age group was (56-65 years) representing 37% of whole study population. Among female patients, 92% were post-menopausal. The prevalence of premature ACS was 51%. Forty five percent of total males and 69.6% of total females with ACS had premature presentation (P<0.001). Abdominal obesity was the most prevalent risk factor (66%). Nearly half of the entire study patients were current smokers (48%). We showed a high prevalence of documented dyslipidemia (48%) as well. Early invasive management strategy was employed in 65% of patients with no significant gender disparity noticed. Vascular access for coronary angiography was most commonly femoral (80% of time). Emergent percutaneous coronary intervention (PCI) was attempted in 53% of patients. Thrombolytic therapy (using Streptokinase) was used in 24% of included participants. Conclusion: Among Egyptian patients with ACS, premature presentation is common with greater male preponderance. Abdominal obesity is the most prevalent risk factor followed by hypertension. Most traditional risk factors (apart from smoking) were more prevalent in women than men.   * A complete list of contributors is available as ad hoc online appendix

2018 ◽  
Vol 21 (1A) ◽  
Author(s):  
Zdzisława Chmiel ◽  
Grażyna Hejda ◽  
Monika Binkowska-Bury

Introduction. A World Health Organization (WHO) conference on a “second wave” epidemic of cardiovascular diseases, directly linked to arterial sclerosis (AS), predicts that in 2020 cardiovascular diseases will most likely be the leading cause of death in the world. The development of AS begins in youth and progresses with age. It’s intensity depends on the risk factors involved, such as: smoking, hypertension, obesity and fat and sugar disorders in the body. Aim. The aim of this study was to establish the risk factors of cardiovascular diseases and their existence, among the youth of the upper gymnasium school. Material and methods. The research was conducted using 511 volunteer students from upper and lower gymnasium schools, between 16-19 years of age. Our research methods included: a diagnostic questionnaire, the measurement of blood pressure (BP) and anthropometric measurements. In the statistical study, we used chi-square independence testing, the V-Kramer test and the tau-b Kendall test; the level of changes α = 0.05 – was used. Results. Over a half of the study group (52.5%) was characterised with the lack of recommended physical activity, much more common in girls than boys (p = 0.000), just like smoking (p = 0.009) which was declared by 39.7% of the interviewed youth. In turn, a heightened value of systolic and diastolic pressure occurred more often in boys (19.6%) than in girls (12.1%); (p = 0.000 vs. p = 0.003). Excessive body mass was noted in 15.7% of the respondents, also more often in boys than in girls (p = 0.02), and abdominal obesity occurred in 10.2% of the respondents, with no significant differences between the sexes. 42.3% of the respondents showed one, 29.9% showed two and 18.8% showed three atherosclerosis risk factors. 9.0% of the study group showed 4 and more such risk factors. Accumulation of atherosclerosis risk factors occurred significantly more often in girls than in boys (p = 0.002). Conclusions. In all the respondents at least one atherosclerosis risk factor was found, and in over half of the study group, more frequently in girls than in boys, an accumulation of two or more risk factors was observed. Lack of recommended physical activity was the most frequent atherosclerosis risk factor occurring in the youth.


Medicina ◽  
2019 ◽  
Vol 55 (10) ◽  
pp. 657 ◽  
Author(s):  
Javad Alizargar ◽  
Chyi-Huey Bai ◽  
Nan-Chen Hsieh ◽  
Shu-Fang Vivienne Wu ◽  
Shih-Yen Weng ◽  
...  

Background and objectives: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD). Previous studies reported controversial results about the independence of CKD as a risk factor for atherosclerosis. In this study, we tried to determine whether the estimated glomerular filtration rate (eGFR) and other renal function tests are independent factors associated with arterial stiffness in community-dwelling individuals with a normal (≥90) or slightly decreased eGFR (60-90). Materials and Methods: Data of 164 community individuals were analyzed, and demographic information, related disease history, atherosclerosis risk factors, certain laboratory tests, the estimated eGFR, and urine albumin creatinine ratio (UACR) were recorded for each individual. Results: The age, systolic blood pressure (SBP), hypertension (HTN), and cardio-ankle vascular index (CAVI) significantly differed between individuals with a normal and those with a slightly decreased eGFR. Blood urea nitrogen (BUN), glycated hemoglobin (HBA1c), and the eGFR significantly differed between the high- and low-CAVI groups and were also significantly correlated with the CAVI. The relationship between the eGFR and CAVI was shown to be independent of other atherosclerosis risk factors in a multiple linear regression model. Conclusions: We concluded that evaluations of the eGFR, HTN, body-mass index, and SBP can be used in a model for arterial stiffness risk assessments for community-dwelling individuals with a normal or slightly decreased eGFR.


2021 ◽  
Vol 8 (4) ◽  
pp. 511
Author(s):  
Chandregowda . ◽  
Mahesh K. ◽  
Anagha Unnikrishnan

Background: Acute coronary syndrome (ACS) is a potentially life‑threatening condition which is more common in elderly people, and young are relatively protected. Its incidence in young Indians is about 12-16%. Currently, the protective effect on young from coronary artery disease (CAD) is taken away by several risk factors. The aim of this study is to determine the conventional and new emerging risk factors like hyperhomocysteinemia and lipoprotein a (Lp [a]) which are suggested to play an important role in myocardial infarction (MI). Methods: This study was a hospital‑based retrospective cross‑sectional analytical study involving 61 patients aged ≤40years presented with signs and symptoms of ACS confirmed by ECG changes and cardiac enzyme levels admitted in the cardiac ICU from April 2019 to March 2020.Results: Although ACS is a less common entity in young adults aged ≤40 years, smoking was the most common cause of the MI (75%) in young adults. Homocysteine and Lp (a) should be measured in young MI patients. Smoking cessation and prevention of diabetes and hypertension (HTN) should be encouraged.Conclusions: Smoking was the most common cause of the MI (75%) in young adults and is the major modifiable risk factor for MI in very young patients which needs strict prevention. Young patients with CAD were mainly males. There is a need for early detection of a risk factor to prevent the progression of ACS,


e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Stivano R. V. Torry ◽  
Lucia Panda ◽  
Jeffrey Ongkowijaya

Abstract: Acute Coronary Syndrome (ACS) is an uncomfortable condition or other symptoms in the chest due to lack of oxygen consumption in myocardium. In 2004, WHO reported that myocard infarct is main cause of death in the world. There is a strong correlation of risk factor to incidence of acute coronary syndrome. Prevention of acute coronary syndrome case is needed by identifying the risk factor that contributes to the acute coronary syndrome to occur. The aim of this study is to investigate the risk factors of acute coronary syndrome. This study is a retrospective cross-sectional. Forty four cases defined as ACS were evaluated in this study, 32 cases were men and 12 cases were women. The majority of ACS cases were 46-55 years old. The risk factor were found were : hypertension were 37 cases, diabetes were 18 cases, raised cholesterol total level were 18 cases, raised LDL level were 32 cases, raised uric acid level were 13 cases, smoking habits were 11 cases. Only 1 cases were having cardiovascular disease history in family.In this study the majority risk factors were hypertension, diabetes, and raised cholesterol level. The highest number of risk factor is 7 risk factors, only 2 cases were having 2 risk factors Keywords: acute coronary syndrome, myocard infarct, risk factor   Abstrak: Sindrom koroner akut (SKA) adalah sebuah kondisi yang melibatkan ketidaknyamanan dada atau gejala lain yang disebabkan oleh kurangnya oksigen ke otot jantung (miokardium). Menurut laporan WHO, pada tahun 2004, penyakit infark miokard akut merupakan penyebab kematian utama di dunia.Sebuah studi menjelaskan hubungan yang kuat antara faktor risiko dengan kejadian sindrom koroner akut. Perlu upaya pengendalian kejadian SKA dengan mengidentifikasi faktor risiko yang berperan terhadap terjadinya SKA.Penelitian yang bertujuan untuk mengetahui gambaran faktor risiko penderita sindrom koroner akut ini menggunakan metode retrospektif dengan studi cross-sectional.Jumlah sampel pada penelitian ini adalah 44 orang. Penderita laki-laki lebih banyak dibandingkan dengan penderita perempuan. Kelompok usia terbanyak yang menderita SKA adalah 46-55 tahun. Terdapat 37 orang penderita yang memiliki tekanan darah di atas normal. Terdapat 18 orang memiliki kadar gula darah puasa meningkat. Kadar kolesterol total meningkat dimiliki oleh 18 orang penderita. Kadar kolesterol LDL meningkat dimiliki oleh 32 orang penderita. Kadar kolesterol HDL rendah dimiliki oleh 15 orang penderita. Tiga belas orang memiliki kadar asam urat tinggi. Sebelas orang memiliki riwayat merokok. Hanya 1 orang memiliki riwayat penyakit kardiovaskuler dalam keluarga. Dapat disimpulkan bahwa faktor risiko utama pada penelitian ini adalah hipertensi, diabetes, dan peningkatan kadar kolesterol. Faktor risiko terbanyak adalah 7 faktor risiko yang dimiliki oleh 3 orang penderita. Hanya 2 orang penderita yang memiliki 2 faktor risiko. Kata kunci:sindrom koroner akut, infark miokard, faktor risiko


Medicine ◽  
2016 ◽  
Vol 95 (11) ◽  
pp. e1357 ◽  
Author(s):  
Leonardo S. Roever ◽  
Elmiro. S. Resende ◽  
Angélica. L. D. Diniz ◽  
Nilson Penha-Silva ◽  
Fernando. C. Veloso ◽  
...  

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 418
Author(s):  
Maria Maroudia Berikopoulou ◽  
Aikaterini Pana ◽  
Theodota Liakopoulou-Tsitsipi ◽  
Nikos F. Vlahos ◽  
Vasiliki Papaevangelou ◽  
...  

Group B streptococcus (GBS) is a leading cause of serious neonatal infections. Maternal GBS colonization is associated with early- and late-onset neonatal disease (EOD/LOD). In Greece, a screening-based strategy is recommended, in which concurrent vaginal-rectal cultures should be obtained between 36 0/7 and 37 6/7 weeks’ gestation. We sought to examine the level of adherence to the GBS screening guidelines and estimate the prevalence of GBS colonization among pregnant women. Although in Greece the screening-based strategy is followed, we also examined known EOD risk factors and linked them to GBS colonization. A cross-sectional study of 604 women postpartum in three hospitals and maternity clinics was conducted. Following written informed consent, data were collected via a short self-completed questionnaire and review of patients’ records. In 34.6% of the enrolled pregnant women, no culture had been taken. Of the remaining, 12.8% had proper vaginal-rectal sample collections. The overall maternal colonization rate was 9.6%. At least one risk factor for EOD was identified in 12.6% of participants. The presence of risk factors was associated with positive cultures (p = 0.014). The rate of culture collection did not differ between women with or without an EOD risk factor. Adherence to a universal screening of pregnant women with vaginal-rectal cultures was poor. Despite probable underestimation of GBS carrier status, almost 1 in 10 participants were GBS positive during pregnancy. Screening of women with risk factors for EOD should, at least, be prioritized to achieve prevention and prompt intervention of EOD.


2008 ◽  
Vol 24 (3) ◽  
pp. 549-554 ◽  
Author(s):  
Maria H. Kniażewska ◽  
Anna K. Obuchowicz ◽  
Tomasz Wielkoszyński ◽  
Joanna Żmudzińska-Kitczak ◽  
Katarzyna Urban ◽  
...  

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