scholarly journals Diphtheria serology in adults in Central Java and East Java, Indonesia: the importance of continuous diphtheria vaccination

2021 ◽  
Vol 21 (3) ◽  
pp. 1148-1154
Author(s):  
Sunarno ◽  
Febriyani Asri ◽  
Subangkit ◽  
Mursinah ◽  
Herna ◽  
...  

Background: Vaccination increase immunity against diphtheria, yet will decrease by aging. Therefore, boosters are needed to be done regularly. Objectives: This study aims to determine the immunity to diphtheria for the population of 16 years old and above. Methods: The sample of study were 295 collected blood serums by Riskesdas project in 2013, the criteria was above 15 years of age and originating from the Provinces of Central Java or East Java inclusively. Immunity assessment was based on antibody titer (IgG) against diphtheria using Vero Cell cytotoxicity test. Statistical analysis was performed using the X2 test. Results: The full protective IgG titer (>0.1 IU/ml) at the age of 16-20 years included 75% sample with a geometric mean titer (GMT) of 0.19 IU/ml. Yet, at the age of 21-60 years and > 60 years, full protective IgG titers only cover 45.5% and 33.3% sample with GMT respectively 0.06 IU / ml. Statistical analysis showed the relationship between age and immune status with p-value 0.003. Otherwise, no relationship between the status of immunity with sex and residency with p-values of 0.16 and 0.43. Conclusions: The immune status against diphtheria at the age of above 15 years decreases with aging. Keywords: Adult; diphtheria; Indonesia; serology.

2020 ◽  
Vol 202 ◽  
pp. 03009
Author(s):  
Tristano Edwan Cancer Ananta ◽  
M. H. Dewi Susilowati ◽  
Ratri Candra Restuti

The city of Surakarta is one of the cultural and historical tourist destinations that continues to develop in Indonesia. The trend of an increase in the number of tourists in 2016-2018 has led to the emergence of many accommodation facilities in the city of Surakarta. Differences in location characteristics in each accommodation facility will affect tourists in choosing accommodation facilities. This study aims to determine the characteristics of the location of accommodation facilities chosen by domestic and foreign tourists in the city of Surakarta, as well as the relationship between the characteristics of the location of accommodation facilities with the characteristics of tourists based on the age and place of origin of tourists. This study uses a spatial comparison analysis method and uses a chi-square statistical analysis to see the relationship between variables, such as the characteristics of the location of accommodation facilities and characteristics of tourists. The results of this study indicate that the location characteristics of the accommodation facilities chosen by foreign and domestic tourists are different. Foreign tourists tend to choose star hotels, while for domestic tourists the choice varies, namely star hotels and non-star hotels. In addition, there is a relationship between the characteristics of domestic tourists with the characteristics of the location of selected accommodation facilities, while for the characteristics of foreign tourists there is no relationship with the characteristics of the location of selected accommodation facilities.


2018 ◽  
Vol 5 (1) ◽  
pp. 16-22
Author(s):  
Jaenudin ◽  
Sandi Aprianto ◽  
Citra Setyo Dwi Andini

Background: Garbage is something material or solid objects that is no used by humans. The impact or risk of improper handling of garbage can cause to environmental damages that can cause health problems and disesase, one of them is diarrhea disease. According to the health profile of West Java Province (2012) showed that the 1.906.886 diarrhea incidence. Cirebon City is ranked ninth with 88,702 diarrhea incidence. Purpose: The purpose of this research is to know the relationship of waste management with the incidence of diarrhea In Argasunya Village Cirebon City. Method: This research used descriptive correlation with kohort retrospekif approach. The population in this study that is all the people who suffer from diarrhea in the Argasunya Village with 72 respondents. The sample in this study using total sampling with 72 respondents who suffer from diarrhea. The research instrument used the observation sheet of waste management and the result of the status of the patient according the medical record data in Sitopeng Public Health Center. The analysis used univariate and bivariate used Chi Square test. Result: The result of univariate analysis showed that most of the waste management did not fulfill the requirement of 59 respondents (81,9%) and most of the acute diarrhea was 62 respondents (86,1%). There was no significant relationship of waste management with the incidence of diarrhea In Argasunya Village Cirebon City, p-value = 0,677.


PEDIATRICS ◽  
1968 ◽  
Vol 41 (3) ◽  
pp. 600-611
Author(s):  
Rebecca H. Buckley ◽  
Susan C. Dees ◽  
W. Michael O'Fallon

In 201 normal individuals from infancy to adulthood, serum concentrations of immunoglobulins G, A, and M are presented as geometric mean values (mg/l00 ml) and as percents of adult mean values for each of these proteins. A statistical analysis revealed a significant relationship between age and both IgG and IgA concentrations up to ages 6 and 7 years. No correlation was present between age and immunoglobulin concentrations beyond that time, suggesting that the adult concentrations of IgG and IgA are normally reached and maintained after ages 6 and 7 years. In contrast, analysis of the IgM data suggested that the adult value is reached by age 1 year. No truly significant differences were found in immunoglobulin concentrations which could be attributed to sex. Significantly higher concentrations of IgG were found in normal Negro than in normal Caucasian subjects after age 6 years, but no significant differences were found below this age for IgG or at any age for IgA and IgM. Similarly determined serum immunoglobulins in 85 allergic children, selected because they had no complicating illnesses, were compared with the normal group according to the age of the child. No significant differences were found in concentrations of either IgG or IgA. Some differences were found in IgM, but these were small and were primarily associated with the relationship of IgM to age in the allergic group.


2021 ◽  
Author(s):  
Huseyin Duman ◽  
Doğan Uğur Şanlı

<p>In the analysis of GNSS time series, when the sampling frequency and time-series lengths are almost identical, it is possible to highlight a linear relationship between the series repeatabilities (i.e. WRMS) and noise magnitudes. In the literature, linear equations as a function of WRMSs allowed many researchers to estimate the noise magnitudes. However, this was built upon homoskedasticity. We experienced the higher WRMSs, the more erroneous analysis results using the noise magnitudes from the linear equations stated. We hence studied whether or not homoscedasticity clearly describes the modeling errors. To test that, we used the published results of GPS baseline components from the previous work in the literature and realized here that each component forms part of the totality. We introduced all baseline component results as a whole into statistical analysis to check heteroskedasticity. We established null and alternative hypotheses on the residuals which are homoscedastic (H0) or heteroskedastic (HA). We adopted both the Breusch-Pagan test and the Goldfeld-Quandt test to prove heteroskedasticity and obtained p-values for both methods. The p-value, which is the probability measure, equals to almost zero for both test methods, that is, we fail to accept the null hypothesis. Consequently, we can confidently state that the relationship between the WRMSs and the noise magnitudes is heteroskedastic.</p><p><strong>Keywords:</strong> Noise magnitudes, repeatabilities, heteroskedasticity, time-series analysis</p>


2021 ◽  
Vol 10 (4) ◽  
pp. 328-334
Author(s):  
Anggrita Salsabila Ramadhia ◽  
Harna Harna ◽  
Mertien Sa'pang ◽  
Nadiyah Nadiyah

Background: Adequate micronutrients intake is essential to ensure the immune function. Certain populations may have insufficient intake of micronutrients, and in situations that increase the demand for example infections, stress, and pollution that decrease the body's stores of micronutrients, putting them at risk of deficiency and may impair immunity. Several researchs related to micronutrient intake, nutritional status, sleep duration are still contradictory results in showing the relationship with immunity.Objectives: To determine the relationship between micronutrient intake, sleep duration, body mass index and the immune status of Balitbang Hukum dan HAM employees.Methods: This type of research is an observational study with a cross sectional approach. The sampling technique used was simple random sampling technique. The samples taken were 47 people.Results: Median intake of micronutrient vitamin A 1024.5 mcg, vitamin C 208.3 mg, vitamin D 1.4 mcg, vitamin E 3.5 mg, iron 5.1 mg, zinc 4.2 mg. Meanwhile, the median sleep duration was 6 hours and the median body mass index was 22.2 kg / m2. The intake of micronutrients with immune status has a p value> 0.05. Sleep duration with immune status has a p value <0.05 with a negative relationship direction. Body mass index with immune status has a p value> 0.05.Conclusion: There is no relationship between micronutrient intake and body mass index with immune status, meanwhile there is a relationship between sleep duration and immune status of Balitbang Hukum dan HAM employees.Keywords : Micronutrient intake; Sleep duration; Body mass index; Immune status


2019 ◽  
Vol 6 (2) ◽  
pp. 108-119
Author(s):  
Ruthy Ngapiyem ◽  
Erik Adik Putra Bambang Kurniawan

Latar Belakang : Halusinasi merupakan  gangguan persepsi dimana  pasien mempersepsikan sesuatu  yang sebenarnya tidak terjadi.  Penatalaksanaan keperawatan pada pasien dengan perubahan sensori persepsi: halusinasi selain diberi pengobatan farmakologi juga dengan dukungan keluarga agar dapat mengontrol halusinasi. Keterlibatan pendukung pasien (keluarga) sangat dapat membantu dalam proses pengobatan dalam kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran. Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga dengan kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Metode Penelitian : Penelitian ini menggunakan desain studi korelasi untuk melihat adanya hubungan dukungan keluarga  dengan kemampuan mengontrol halusinasi pendengaran pada klien halusinasi pendengaran. Besar sampel dalam penelitian ini mengunakan kriteria sampling sebagai berikut: Populasi < 100 diambil total/ semua sampling. Dalam penelitian ini, jumlah sampelnya berjumlah 40 responden. Hasil Penelitian : Berdasarkan hasil uji statistic chi-square didapatkan nilai P-value > α yaitu (0,356 > 0,05) yang artinya tidak ada hubungan antara dukungan keluarga dengan kemampuan klien mengontrol halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Kesimpulan dan Saran : Tidak ada hubungan antara dukungan keluarga dengan kemampuan klien mengontrol halusinasi pendengaran di Poli Jiwa RSJD Dr. RM Soedjarwadi Provinsi Jawa Tengah tahun 2018. Diharapkan bagi peneliti selanjutnya meneliti terkait dengan faktor apa saja yang dapat mendukung kemampuan mengontrol halusinasi pendengaran.   Kata Kunci : dukungan keluarga, halusinasi pendengaran, kemampuan mengontrol halusinasi pendengaran   ABSTRACT   Background: Hallucinations are perceptual disorders where patients perceive something that really doesn't happen. Nursing management in patients with hallucinations besides being given pharmacological treatment also with family support in order to control hallucinations. The involvement of supporting patients (families) can greatly assist in the treatment process in the ability to control auditory hallucinations in auditory hallucinations clients. Objective: This study aims to determine the relationship of family support with the ability to control auditory hallucinations in auditory hallucinations clients at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. Method: This study uses a correlation study design to see the relationship of family support with the ability to control auditory hallucinations in auditory hallucinations clients. The sample size in this study used the following sampling criteria: Population <100 was taken total/ all sampling. In this study, the number of samples was 40 respondents. Result: Based on the results of the chi-square statistical test, the value of P-value> α is obtained (0.356> 0.05) which means there is no relationship between family support and the client's ability to control auditory hallucinations at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. Conclusion and Reccomendation: There is no relationship between family support and the client's ability to control auditory hallucinations at the Psychiatric Psychology RSJD Dr. RM Soedjarwadi Province of Central Java in 2018. It is hoped that the next researcher will examine the related factors that can support the ability to control auditory hallucinations.   Keywords : family support, auditory hallucinations, ability to control auditory hallucinations


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Nikola Sprigg ◽  
Katie Robson ◽  
Zhe K Law ◽  
Jason Appleton ◽  
Philip Bath

Background: Intensive lowering of blood pressure in the hyperacute phase after intracerebral haemorrhage may improve outcome (as observed in the INTERACT-2 trial) or have no effect (ATACH-2). Clinical guidelines recommend BP lowering. Methods: We investigated the relationship between BP, and BP lowering treatment on functional outcome, death and serious adverse events at day 90. Statistical models were adjusted for baseline characteristics. Results: As at 18 th July 2016, 1161 (71.4%) of patients were on BP lowering treatment by day 2; these patients were younger (mean (SD): 67.7 (13.9) vs 71.9 (12.9) years, p-value<0.0001), more likely to be male (660/1161 (56.9%) vs 241/466 (51.7%), p-value=0.0598) and had lower NIHSS at baseline (12.5 (7.2) vs 14.2 (8.0), p-value<0.0001). Patients on BP lowering were found to have significantly better mRS and Barthel Index by day 90 (p-values: 0.0171, 0.0482, respectively) as compared to those not on treatment, and fewer of these patients died or suffered an SAE (p-values: 0.0074, 0.0002, respectively). However, there was no relationship between systolic BP levels (<140 vs >= 140 mmHg) on day 2, and outcome at day 90. Conclusion: Early BP lowering is associated with improved functional outcome, and fewer deaths and SAEs, at day 90. Those achieving a BP target of <140mmHg by day 2 did not have a better outcome, suggesting that the optimal BP target may need more investigation.


2019 ◽  
Vol 11 (1) ◽  
pp. 1-10
Author(s):  
Yufi Yufi Aliyupiudin

Nosocomial infection or also called hospital-acquired infection occurs in patients who are hospitalized for at least 72 hours and the patient does not show symptoms of infection when admitted to hospital. Riskes data shows the level of nosocomial infection in Indonesia reaches 6-16% with an average of 9.8%. In 2006 Indonsia had the percentage of nosocomial infections was obtained in Lampung Province reached 4.3%, Jambi 2.8%, DKI Jakarta 0.9%, West Java 2.2%, then Central Java 0.5%, and Yogyakarta 0.8 %. Knowing the relationship between nurses' knowledge about nosocomial infections on the prevention behavior of nosocomial infections in the Salak hospital operating room Bogor in 2018 This type of research uses quantitative analytic descriptive study with Cross Sectional research design. The sampling method uses total sampling with the population are nurses in the operating room and data were obtained by 30 respondents. The data collection is obtained through questionnaires. The results showed that from a total of 30 respondents 17 respondents (56.7%) stated that nurses were well-informed, 18 respondents (60.0%) stated that nurses behaved positively. The results of the behavior of prevention of nosocomial infection there were 16 respondents (53.3%) nurses had knowledge with positive behavior. The results of statistical tests obtained p value = 0,000 which means that p value <0.05. At the conclusion of the statistical test, there was a relationship between nurses' knowledge about nosocomial infections on the prevention behavior of nosocomial infections in the operating room Salak hospital of Bogor in 2018


2019 ◽  
Vol 4 (4) ◽  
pp. 2473011419S0009
Author(s):  
Chayanin Angthong ◽  
Prasit Rajbhandari

Category: Ankle, Sports Introduction/Purpose: Posterior talofibular ligament is one of the lateral ligamentous complex of the ankle. However, little is known about its anatomic profile especially on the relationship between its length and the morphometric profiles of talus. The present was to analyze the correlations between PTFL length and the talar morphometric profiles in the cadaveric specimens. The PTFL variation was also reported in this study. Methods: A total of twenty four cadaveric ankles as twelve matched pairs of ankle were collected in this study. All ankles were measured with a Vernier caliper which provided the data for further analysis regarding the PTFL length and the talar morphometric profiles. The data was calculated to demonstrate the relationship between PTFL length and the morphometric profiles of talus. There was a cadaveric ankle which was not used in the study due to its absence of PTFL. Results: An average length of PTFL was 23.9+/-6.9 mm. In overall, an average talar length (TaL) was 53.5 millimeters (mm). An average talar dome height (TaH) was 31.2 mm. An average talar body width (TaW) was 41.3 mm. The average anterior trochlear width (TrAW), middle trochlear width (TrMW), posterior trochlear width (TrPW), and trochlear length (TrL) were 31.8, 31.2, 28.3, and 30.7 mm. Based on twenty three ankles, the paired samples T-test showed the significantly negative correlations between PTFL length and TrL (Pearson’s r correlation coefficient: -0.432; P-value: 0.039). Other correlations were in negative values but P-values > 0.05. There were 16 ankles (84.2%) with 1 PTFL band and 3 ankles (15.8%) with 2 bands from 19 ankles with complete data. Conclusion: The present study may be a first study which delineates the relationship between PTFL length and the morphometric profiles of talus. The PTFL length was negatively correlated with talar size especially on the trochlear length of talus.


2014 ◽  
Vol 9 (11) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Eriko Fukuda ◽  
Yoshihiro Uesawa ◽  
Masaki Baba ◽  
Ryuichiro Suzuki ◽  
Tatsuo Fukuda ◽  
...  

In order to identify the country of growth of Sophora flavescens by chemical fingerprinting, extracts of plants grown in China and Japan were analyzed using direct analysis in real time mass spectrometry (DART)-MS. The peaks characteristic of each country of growth were statistically analyzed using a volcano plot to summarize the relationship between the p-values of a statistical test and the magnitude of the difference in the peak intensities of the samples in the groups. Peaks with a p value <0.05 in the t-test and a ≥2 absolute difference were defined as characteristic. Peaks characteristic of Chinese S. flavescens were found at m/z 439 and 440. In contrast, peaks characteristic of Japanese S. flavescens were found at m/z 313, 423, 437 and 441. The intensity of the selected peaks was similar in Japanese samples, whereas the m/z 439 peak had a significantly higher intensity than the other peaks in Chinese samples. Therefore, differences in selected peak patterns may allow identification of the country of growth of S. flavescens.


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