scholarly journals TO ESTABLISH TREATMENT MODALITIES IN SEASONAL NON-COMMUNICABLE CHRONIC DISORDERS W. S. R. TO “TAMAKA SHWASA” AS PRANAVAHA PRADOSHAJA VIKARA

2021 ◽  
Vol 9 (11) ◽  
pp. 2713-2722
Author(s):  
Sushil Kumar Jangid ◽  
Sunita Kumari Bijarniya
Keyword(s):  
Clinical Study ◽  
Bronchial Asthma ◽  
The Body ◽  
Treatment Modalities ◽  
Group Iii ◽  
Philosophy Of Life ◽  
Group I ◽  
Mild Improvement ◽  
Group 2 ◽  
And Function

Ayurveda is not only the science of life but also the philosophy of life. Srotasa which represent the internal transport system includes a series of channels through which Rasa-Raktaadi Dhatu is propelled to all parts of the body. The concept of Pranavaha Srotodushti & its explanation matches entirely with the pathogenesis mechanism symptoms of Asthma. Taking this aspect in the mind, the clinical study was planned to establishment of the func- tional utility of Srotomoola in the management of the disease Tamaka Shwasa. AIM & OBJECTIVES: To estab- lish the role and function utility of Srotomoola. To study the aetiopathogenesis and treatment of Pranavaha- Pradoshaja Vikara. To assess the efficacy of Shwashar Yoga, Hridya Yoga, and Deepaniya Yoga. MATERIALS AND METHODS: For the clinical study 30 clinically diagnosed patients of Tamaka Shwasa (Bronchial Asthma) were registered for present clinical. They were treated in three groups randomly each containing 10 patients with- in the age group of 20-70 years. Group 1 has been treated with Shwashar Yoga 5gm three times a day for 2 months. Group 2 have given Hridya Yoga 5gm three times a day for 2 months. Group 3 have given Deepaniya Yoga 5gm three times a day for 2 months. 30 clinically diagnosed patients of Tamaka Shwasa (Bronchial Asthma) were registered for the present clinical study in 3 divided groups. RESULTS: After the complete intervention the overall improvement in the patient of group I was found to be 77.27%, in Group II was found to be 63.64% and in group III was found to be 31.50% which was a mild improvement symptomatically but statistically it was highly significant. DISCUSSION AND CONCLUSION: It was observed that most drug ingredients in Shwashar Yoga, Hridya Yoga, Deepaniya Yoga have Laghu, Ruksha, Tikshna Guna, Tikta, Katu Rasa, Katu & Madhura Vipaka & Kapha Vatashamaka Prabha- va. Considering these factors, the selected drugs as well comprises Kapha Vatashamaka action, moreover, should contain a strong affinity to perform on Pranavaha Srotas. It shows signs of Srotoshodhaka properties which may assist to eliminate sluggish Dosha in the Srotas. Keywords: Srotasa, Srotomoola, Tamaka Shwasa, Kapha Vatashamaka.

scholarly journals Evidence of Regeneration of Testicular and Epididymal Tissue Structure and Function Following Withdrawal from Sub-chronic Khat Exposure: Studies in the Rabbit Animal Model

2020 ◽  
pp. 10-23
Author(s):  
Albert W. Nyongesaa ◽  
Esther M. Malukib ◽  
Jemimah A. Simbaunib
Keyword(s):  
Body Weight ◽  
Chronic Exposure ◽  
Structure And Function ◽  
The Body ◽  
Endocrine Function ◽  
Eastern Africa ◽  
Blood Samples ◽  
Middle East Countries ◽  
Group I ◽  
And Function

Khat, Catha edulis, use is rampant in Eastern Africa and Middle East countries with associated reports of reproductive function impairment in the body of the user. Reports on recovery post long-term khat exposure are obscure. The present study investigated evidence of restoration of testicular and epididymal structure and function during withdrawal from cytotoxic damage caused by sub-chronic exposure of khat extract. Twenty-eight male rabbits were divided into 7 groups of 4 rabbits each. Group I (control) was administered normal saline while groups II, III and IV were administered 1.0 g/kg, 10 g/kg and 20 g/kg body weight of khat extract, respectively, via oral gavage on alternate days of the week for 12 weeks. Blood samples from animals were collected for hormonal assays followed by euthanasia using 26.4 mg/kg body weight of Sagatal sodium intramuscularly for testicular and epididymal histology. Group V, VI and VII were administered 1.0 g/kg, 10 g/kg and 20 g/kg body weight of khat extract, respectively, orally on alternate days of the week for 12 weeks followed by 1-month withdrawal period, blood samples collected for hormone assays and animals sacrificed for testicular and epididymal histology. High khat dose, 20 g/kg body weight, at sub-chronic exposure caused degeneration in spermatogenic cells with accompanying decrease in plasma FSH and testosterone. Histological output of Sertoli cells, Leydig cells and epididymal epithelium appeared unaffected in treatment groups. Post withdrawal data showed apparent regeneration of seminiferous epithelium and restoration of plasma FSH and testosterone comparable to control. It appears khat extract preferentially affected germ cell spermatogonia and subsequent daughter cells while stem cell spermatogonia were unaffected and contributed to regeneration of germinal epithelium and endocrine function.

scholarly journals Anaesthesia Circuits, Humidity Output, and Mucociliary Structure and Function

1998 ◽  
Vol 26 (2) ◽  
pp. 178-183 ◽  
Author(s):  
R. D. Branson ◽  
R. S. Campbell ◽  
K. Davis ◽  
D. T. Porembka
Keyword(s):  
Minute Ventilation ◽  
Absolute Humidity ◽  
Tracheobronchial Tree ◽  
Open Circuit ◽  
Structure And Function ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
And Function ◽  
Circuit Technique

We compared the effects of humidity delivered by the circle system at low fresh gas flows (FGF) with a conventional two-limb and coaxial circuit on the structure and function of the tracheobronchial epithelium in dogs. Animals were anaesthetized and mechanically ventilated using an anaesthesia ventilator to maintain normocarbia. Group I (control) animals received a FGF equal to the required minute ventilation mimicking an open circuit technique. Group II and III animals had FGF set at 20% of the required minute ventilation. Group II used a two-limb circuit and Group III used a coaxial circuit. Relative humidity and temperature of inspired gases were measured at baseline and hourly afterwards. In the first experiment, biopsies of the tracheobronchial tree were obtained bronchoscopically at baseline and then hourly for six hours. Microscopic examination of these samples allowed calculation of mean ciliary length. In the second experiment, tracheal mucus flow velocity (TMFV) was measured at baseline and hourly afterward, using a cinebroncho-fibrescopic method. Delivered absolute humidity was greatest with low FGF and the coaxial circuit, followed by low FGF and a conventional circuit, and high FGF (15±1.4 vs 9±0.8 vs 5±0.4 mg H2O, P<0.01) after two hours. Mean cilia length (μ m) and TMFV (mm/min) fell during the first hour in all three groups. At hour two TMFV returned to baseline in Group III and was significantly greater than Groups I and II (0.8±0.4 vs 8.6±1.1 vs 15.4±2.1, P<0.001). Mean ciliary length demonstrated a similar pattern with reductions from baseline in all three groups for the first two hours. Groups II and III had an increase in cilia length beginning at hour three and were both significantly greater than Group I at hours 3 through 6 (1.3±0.5 vs 3.2±1.1 vs 4.2±0.8, P <0.001). Alterations in tracheobronchial structure and function result from exposure to dry gases and are amplified by the duration of exposure. Our findings suggest a minimum of 12 to 15 mg H2O/l is necessary to prevent these alterations. In this study, the combination of low FGF and a coaxial anaesthesia circuit reached this minimum threshold more quickly than a conventional two-limb circuit.

A note on the effect of weaning age on lamb production

1969 ◽  
Vol 11 (4) ◽  
pp. 569-572
Author(s):  
M. A. Sharafeldin ◽  
I. A. Ramadan
Keyword(s):  
Mortality Rates ◽  
The Body ◽  
The Other ◽  
Suckling Period ◽  
Group Iii ◽  
Group I ◽  
Body Weights ◽  
Weaning Age ◽  
Group Ii ◽  
Better Than

SUMMARYAt birth, the Barki lambs used in this experiment were randomly allocated to three groups which numbered 133, 126 and 154 lambs of both sexes weaned at the ages of 10 weeks (Group I), 12 weeks (Group II) and 16 weeks (Group III) respectively.The most pronounced differences between the three groups of lambs in their body weights took place at the age from 4 to 6 months. Group II lambs performed as well as or even slightly better than the other two groups, which leads to the conclusion that as far as the body weight of lambs is concerned there is no need to extend their suckling period more than 12 weeks.The three groups of lambs varied little in their mortality rates from 2·5 to 12 months of age.

scholarly journals Effectiveness of EDTA and EDTA-T brushingm on the removal of root surface smear layer

2003 ◽  
Vol 17 (4) ◽  
pp. 319-325 ◽  
Author(s):  
José Eduardo Cezar Sampaio ◽  
Ricardo Samih Georges Abi Rached ◽  
Gibson Luiz Pilatti ◽  
Letícia Helena Theodoro ◽  
Luiz Henrique Carvalho Batista
Keyword(s):  
Root Surface ◽  
Smear Layer ◽  
Treatment Modalities ◽  
Control Group ◽  
Group Iii ◽  
Layer Removal ◽  
Group I ◽  
Control Application ◽  
Root Surfaces ◽  
Gel Ph

The purpose of this study was to compare the removal of root surface smear layer following active application of EDTA gel and EDTA-T (texapon) gel in different concentrations (5%, 10%, 15%, 20% and 24%), using scanning electron microscopy. A total of 220 dentin blocks obtained from the root surfaces of extracted teeth were divided into 3 groups: Group I - (control) application of saline solution (n = 20); Group II - EDTA gel (pH 7.0) was applied in the following concentrations: 5%, 10%, 15%, 20% and 24% (n = 100); Group III - EDTA-T gel (pH 7.0) applied in the same concentrations described above (n = 100). The photomicrographs were evaluated by one calibrated examiner using a smear layer removal index and following statistical analysis (Kruskal-Wallis test). The results demonstrated that the specimens treated with EDTA and EDTA-T gel presented a better smear layer removal than the control group (p < 0.01); no statistically significant differences were observed between the EDTA and EDTA-T groups and between the concentrations tested (Mann-Whitney, p > 0.05). Within the limits of this study, it can be concluded that all treatment modalities effectively removed the smear layer from the root surface. The addition of texapon into the EDTA gel formulation did not increase its effectiveness.

scholarly journals A preoperatív antibiotikus és antiszeptikus kezelés hatása a műtéti úton eltávolított alsó bölcsességfogak sebgyógyulására – prospektív randomizált vizsgálat

2017 ◽  
Vol 158 (1) ◽  
pp. 13-19 ◽  
Author(s):  
István Kaposvári ◽  
Kinga Körmöczi ◽  
Zsuzsa Beáta László ◽  
Ferenc Oberna ◽  
Ferenc Horváth ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Third Molar ◽  
Control Group ◽  
Surgical Removal ◽  
Group Iii ◽  
Prophylactic Dose ◽  
Group I ◽  
Mandibular Third Molar ◽  
Amoxicillin Clavulanate ◽  
Group 2

Abstract: Introduction and aim: The study compares the antibiotic prophylaxis combined with postoperative antibiotic therapy to preoperative chlorhexidine rinse combined with postoperative antibiotic therapy in preventing complications after surgical removal of a mandibular third molar. Method: 71 healthy patients in four groups were enrolled in the study: I. prophylactic dose of 2000 mg of amoxicillin clavulanate, continued with amoxicillin clavulanate postoperatively; II. prophylactic dose of 600 mg of clindamycin, continued with clindamycin postoperatively; III. prophylactic chlorhexidin rinsing, continued randomized amoxicillin clavulanate or clindamycin postoperatively; IV. control, with clindamycin postoperatively. Results: The pain was smaller in the prophylaxis groups. Alveolitis occurred only in the control group: 2 patients. Wound opening occurred in 22,2 % in group IV., 14,2 % in group II, 10 % in group I., 5 % in group III. Conclusion: We consider completing the indicated postoperative antibiotic prescription with antibiotic or antiseptic prophylaxis. Chlorhexidin prophylaxis could have the same positive effect. Orv. Hetil., 2017, 158(1), 13–19.

scholarly journals Investigation of the Protective Effects of Taurine against Alloxan-Induced Diabetic Retinal Changes via Electroretinogram and Retinal Histology with New Zealand White Rabbits

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Samuel Tung-Hsing Chiang ◽  
Shang-Min Yeh ◽  
Yi-Chen Chen ◽  
Shiun-Long Lin ◽  
Jung-Kai Tseng
Keyword(s):  
Body Weight ◽  
Protective Role ◽  
The Body ◽  
Antidiabetic Activity ◽  
Protective Effects ◽  
Group Iii ◽  
Glucose Levels ◽  
Diabetic Retina ◽  
Group I ◽  
Group Ii

The purpose of this study was to investigate the protective role of orally administered taurine against diabetic retinal changes via electroretinogram (ERG) and retinal histology on rabbits. Rabbits were randomly assigned into groups: Group I (vehicle administration only); Group II (diabetes: induced by 100 mg/kg alloxan injection); Group III (diabetes and fed with 200 mg/kg taurine); and Group IV (diabetes and fed with 400 mg/kg taurine). The body weight and blood glucose levels of the rabbits were monitored weekly. The ERG was measured on weeks 5 and 15. Retinal histology was analyzed in the end of the experiment. Results revealed that a taurine supplement significantly ameliorates the alloxan-induced hyperglycemia and protects the retina from electrophysiological changes. Group II showed a significant(P<0.05)change in the mean scotopic b-wave amplitude when compared to that of Group I, whereas the diabetic rabbits treated with taurine (Group III and IV) were analogous to Group I. Histologically, the amount of Bipolar and Müller cells showed no difference(P>0.05)between all groups and when compared with those of Group I. Our study provides solid evidences that taurine possesses an antidiabetic activity, reduced loss of body weight, and less electrophysiological changes of the diabetic retina.

scholarly journals DNA Analysis of Ralstonia solanacearum and Related Bacteria Based on 282-bp PCR-Amplified Fragment

Plant Disease ◽  
2003 ◽  
Vol 87 (11) ◽  
pp. 1337-1343 ◽  
Author(s):  
Joselito Villa ◽  
Kenichi Tsuchiya ◽  
Mitsuo Horita ◽  
Marina Natural ◽  
Nenita Opina ◽  
...  
Keyword(s):  
Ralstonia Solanacearum ◽  
Dna Analysis ◽  
Restriction Analysis ◽  
Polymerase Chain Reaction Amplification ◽  
Restriction Enzymes ◽  
The Philippines ◽  
Restriction Fragments ◽  
Group Iii ◽  
Group I ◽  
Group 2

Strains of Ralstonia solanacearum, Pseudomonas syzygii, and the blood disease bacterium (BDB) from different countries were tested for polymerase chain reaction amplification of the 282-bp fragment using the primer pair 759 and 760. These 282-bp fragments from 49 strains of R. solanacearum, six strains of P. syzygii, and two strains of BDB were sequenced. A phylogenetic tree was generated based on the sequence alignment. The R. solanacearum strains were divided into three groups. Group I was composed of strains belonging to biovars 3, 4, 5, and biovar N2 from Japan. Most of the strains from this group were of Asian origin except for two strains from Australia and Guyana (GMI 1000), the type strain. Group II was composed of strains belonging to biovars 1 and 2 and biovar N2 from Brazil. Group III was composed of strains belonging to biovar N2 from Japan and the Philippines. All strains of P. syzygii and BDB clustered in group III. Based on nucleotide differences of the 282-bp fragments, restriction enzyme NlaIII was capable of differentiating R. solanacearum strains into the three groups. Restriction analysis of 165 R. solanacearum isolates from the Philippines using NlaIII showed that all biovar 3 and 4 (group 1) strains had restriction fragments of 116 and 166 bp, strains belonging to biovars 1 and 2 (group 2) showed no restriction, and one strain belonging to biovar 2 (group 3) showed restriction fragments of 54 and 228 bp in size. Thus, NlaIII could be used for rapid differentiation of R. solanacearum strains. Additionally, other restriction enzymes, such as McrI, BsiEI, and MnlI could be used to differentiate R. solanacearum strains from P. syzygii strains.

scholarly journals Sustained Attention and Types of Dynamics of Cardiovascular Reactivity during a Short-Term, Human Whole-Body Exposure to Cold Air

2020 ◽  
Vol 10 (4) ◽  
pp. 407-411
Author(s):  
Olga Krivonogova ◽  
Elena Krivonogova ◽  
Liliya Poskotinova
Keyword(s):  
Processing Speed ◽  
The Body ◽  
Whole Body ◽  
Short Term ◽  
Cold Air ◽  
Group I ◽  
Baseline Values ◽  
Group 2 ◽  
Stage 1 ◽  
Group 1

Background: Despite global warming and the improvement of personal protective equipment against unfavorable climatic factors, cold remains an important environmental challenge for humans. The aim of the work was to reveal the peculiarities of the dynamics of cardiovascular parameters in humans with short-term, whole-body exposure to cold air, depending on the parameters of voluntary attention. Methods and Results: The study involved 28 healthy male volunteers aged between18 and 21 years, born and living in Arkhangelsk. Testing to assess sustained attention parameters using the Toulouse-Pierón Attention Test with the measurement of the index of accuracy (C, units) (the ability to voluntary concentration) and processing speed (V, units), had been previously performed. Subsequent stages of the study included recording the studied parameters before (Stage 1), during 10-minute exposure to the cold air (Stage 2), and 5 minutes after cold exposure (Stage 3). The registration of indicators in Stages 1 and 3 was carried out indoors at an air temperature of +20 °C. The registration of indicators in Stage 2 was carried out in a cold chamber at -20 °C. Determining the body temperature in the ear canal (Tear, °C) and on the skin of the dorsum of the right hand (Tskin, °C) was performed using a B.Well WF-1000 medical electronic infrared thermometer. Parameters of blood pressure (SBP and DBP) and heart rate variability (HRV) were evaluated. As a result of cluster analysis, 2 groups were identified: Group 1 (n=14) and Group 2 (n=14). In Group 2, the index V was significantly lower than in Group 1(P=0.02). In Group I, Tskin in Stage 1 was significantly higher than in Group 2 (P=0.03). In Stage 2, Tskin decreased in both groups, but lower Tskin values (P=0.001) were recorded in Group 2 than in Group I. In Stage 2, there was a statistically significant increase in SBP in Group 2 (P=0.01). In Group 1, initial SDNN and all HRV spectral indices were significantly higher than in Group 2. In Stage 2, there was a significant increase in SDNN in both groups. However, in Group 2, we found a statistically significant increase in VLF in Stage 2 (P=0.01), while in Group I this indicator remained unchanged. In Stage 3, HRV parameters in Group 1 recovered to baseline values, while in Group 2, HRV parameters remained elevated relative to baseline values. Conclusion: Individuals with high processing speed and preserved attention span have higher vagal activity and skin temperature. When such individuals are exposed to cold, they experience a moderate increase in BP and baroreflex response. In persons with a reduced speed of information processing but with sufficient accuracy of attention, there is a more pronounced mobilization of regulation resources on the part of the cardiovascular, neurovegetative systems to maintain the core temperature of the body.

scholarly journals DUAL EFFECT OF ATORVASTATIN ON ENDOTHELIUM

2015 ◽  
Vol 22 (09) ◽  
pp. 1196-1202
Author(s):  
Faizania Shabbir ◽  
Muhammad Alamgir Khan ◽  
Tausif Ahmed Rajput
Keyword(s):  
Colorimetric Method ◽  
The Body ◽  
Sprague Dawley ◽  
Dual Effect ◽  
Immunosorbant Assay ◽  
Group Iii ◽  
Medical College ◽  
Group I ◽  
Randomized Control ◽  
Enzyme Linked Immunosorbant Assay

Objective: The objective of the study was to observe the effect of lipid loweringtherapy on homocysteine and TXA2 concentration in obese hyperlipidemic Sprague Dawleyrats. Design: Randomized Control Trial (RCT). Place and Duration of study: The study wasconducted in Department of Physiology and Centre for Research in Experimental and AppliedMedicine (CREAM), Army Medical College, Rawalpindi; and National Institute of Health (NIH)Islamabad over a period of 12 months. Methodology: Ninety healthy Sprague Dawley ratsdivided into three equal groups. Group I (n=30) were healthy controls, group II (n=30) weremade obese and group III (n=30) were obese treated (atorvastatin 10 mg/kg/day orally bygavage method for three weeks). Body weight was recorded thrice weekly, lipid profile wasmeasured by colorimetric method on microlab and homocysteine and TXA2 were measuredby Enzyme Linked Immunosorbant Assay. Results: Serum low density lipoproteins and TXA2decreased after three weeks of atorvastatin administration, elevated HCY concentration in obesehyperlipidemic rats however was not significantly affected. Conclusion: Atorvastatin apart fromlowering lipid levels in the body also reduces TXA2 concentration which is a vasoprotective.Elevated HCY concentration which is deleterious to the endothelium however is not affected.

scholarly journals GAMBARAN HISTOPATOLOGI HATI TIKUS WISTAR YANG DIBERIKAN JUS TOMAT (Solanum Lycopersicum) PASCA KERUSAKAN HATI WISTAR YANG DIINDUKSI KARBON TETRAKLORIDA (CCl4)

2013 ◽  
Vol 1 (3) ◽  
Author(s):  
Eka Sari Tappi ◽  
Poppy Lintong ◽  
Lily Loho
Keyword(s):  
Carbon Tetrachloride ◽  
Wistar Rats ◽  
Liver Cells ◽  
The Body ◽  
Tomato Juice ◽  
Control Group ◽  
Histopathological Changes ◽  
Group Iii ◽  
Group I ◽  
Group Ii

Abstract: Liver is the largest organ in the abdominal cavity. As the center of metabolism in the body, liver is potentially damaged by exposure of toxic substances, inter alia carbon tetrachloride (CCl4). Metabolism of carbon tetrachloride (CCl4) produces CCl3 free radicals that can damage the liver. In Indonesia, there are a lot of natural ingredients that have antioxidant properties, such as tomato. Lycopene in tomatoes contains antioxidant compounds that can prevent damages due to free radical. This study aimed to obtain liver histopathological changes of wistar rats fed with tomato juice after being induced of carbon tetrachloride (CCl4). This was an experimental study, using 10 wistar rats which were divided into 4 groups. Group I was the negative control; group II was induced with CCl4 0,05 cc/day and was terminated on day 6; group III was induced with CCl4 0,05 cc/day and was given tomato juice 3 ml/day, and terminated on day 13; group IV was induced by CCl4 0,05 cc/day, given regular pellets, and terminated on day 13. The results showed that group II had histopathological changes of the liver indicating fatty liver, meanwhile group III showed regeneration of nearly all liver cells. Conclusion: Administration of tomato juice after the induction of 3 ml carbon tetrachloride (CCl4) for 7 day showed regeneration of almost all liver cells. Keywords: histopathological changes of the liver, carbon tetrachloride, tomato juice.   Abstrak: Hati merupakan organ terbesar dalam rongga abdomen, dan pusat metabolisme tubuh dengan fungsi yang sangat kompleks dan sangat berpotensi mengalami kerusakan akibat terpapar oleh bahan-bahan toksik, salah satunya yaitu karbon tertraklorida (CCL4). Metabolisme CCl4 menghasilkan radikal bebas CCl3 yang dapat merusak hati. Di Indonesia terdapat  banyak sekali bahan-bahan alami yang mempunyai kandungan antioksidan, salah satunya yaitu tomat. Tomat mengandung senyawa likopen sebagai antioksidan yang dapat mencegah kerusakan jaringan akibat radikal bebas. Penelitian ini bertujuan untuk mendapatkan gambaran histopatologi hati tikus wistar yang diberi jus tomat pasca induksi karbon tetraklorida (CCl4). Metode penelitian ialah eksperimental. Sampel sebanyak 10 ekor tikus wistar yang dibagi dalam 4 kelompok. Kelompok I sebagai kontrol negatif; kelompok II diinduksi CCl4 0,05cc/perhari dan diterminasi hari ke-6; kelompok III diinduksi CCl4 0,05 cc/hari kemudian diberikan jus tomat 3ml/hari;  dan kelompok IV diinduksi CCl4 0,05 cc/hari kemudian diberikan pelet biasa dan diterminasi hari ke-13. Hasil penelitian menunjukkan pada pemberian CCl4 pada tikus wistar selama 5 hari terdapat gambaran morfologik perlemakan sel hati. Pemberian jus tomat dosis 3 ml pasca induksi karbon tetraklorida (CCl4) menunjukkan terjadinya regenerasi pada hampir seluruh sel-sel hati. Simpulan: Pemberian jus tomat dosis 3 ml pasca induksi karbon tetraklorida (CCl4) selama 7 hari menunjukkan regenerasi pada hampir seluruh sel-sel hati. Kata kunci: gambaran histopatologi hati, karbon tetraklorida, jus tomat.

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