Formulation and Stability Test of Lip Cream Preparation of Kenop Flower Ethanol Extract (Gomphrena globosa L.)

Author(s):  
Mevi Irianti Tonapa ◽  
Rani Dewi Pratiwi ◽  
Elsye Gunawan

Kenop Flower (Gomphrena globosa L.) is used in the manufacture of lip cream because contains betacyanin pigments that function as color pigments. This study aims to determine the physical quality and stability of the lip cream preparation of the ethanol extract of kenop flower (Gomphrena globosa L.). This research was conducted experimentally, including the manufacture of lip cream formulations with ethanol extract of kenop flower (Gomphrena globosa L.) with a concentration of 10%. The results of the physical examination test for lip cream preparations for all preparations have a distinctive vanilla aroma with a semi-solid texture, F0 has ivory white color and F1-F3 has a brown color. The preparations had a homogeneous composition, average pH 6-7, had good greasing power, 5.0-5.8 average dispersion and 60.33-66.67 seconds average adhesion. The stability test carried out on day 28 found that all preparations were stable, had a distinctive vanilla aroma with a semi-solid texture, F0 had ivory white color and F1-F3 had a brown color. The preparation has a homogeneous composition; the average pH is 6-7. Where the lip cream formulas F1 and F3 decreased the pH value on the 28th day from 7 to 6 but tended to be stable and in the pH range that matched the lip pH. And there is no phase separation in all formulas.

Author(s):  
W. C. C. S. Sá ◽  
E. M. Santos ◽  
J. S. de Oliveira ◽  
G. G. L. de Araujo ◽  
A. F. Perazzo ◽  
...  

Abstract The objective of this study was to evaluate the fermentative characteristics and chemical composition of cochineal nopal cactus silage additives with urea or Lactobacillus buchneri (LB), as well as the association of both additives in four storage times (7, 15, 60 and 120 days) and during aerobic stability, with evaluations at 0, 48 and 96 h. Four silages were used: no additive, addition of 2% urea, addition of LB and addition of 2% urea and LB. The study was divided into two experiments: the first experiment evaluated the silages at different storage times, and the second experiment evaluated the silages during the aerobic stability test. In both experiments, the experimental design was completely randomized in a factorial scheme (4 × 4 and 4 × 3) with three replicates per treatment. After the ensiling process, lactic acid bacteria predominated in all treatments. The concentration of lactic acid increased significantly from 60 days of ensiling. The concentration of acetic acid varied significantly between the storage times only for the silages treated with urea and LB alone. The silage treated with urea maintained a constant pH value up to 120 days of storage. During the 96 h aerobic stability test, no breaking in the stability of silages was observed. The exclusive or associated use of urea and LB promotes improvement in the fermentative characteristics of cochineal nopal cactus silage, without major alterations in the chemical composition or interfering with the aerobic stability of the silages.


PHARMACON ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 487
Author(s):  
Grace Dien Manik ◽  
Hosea J. Edy ◽  
Elly J. Suoth

ABSTRACT Purple Sweet Potato (Ipomoea batatas L.) and Red Cana Flower (Canna coccinea Mill.) contain natural dyes (anthocyanins) which are used as an alternative natural dyes as well as natural antioxidants. This study aims to make and discover the physical evaluation of blusher preparations using natural dyes in a combination of Purple Sweet Potato extract and Red Cana Flower with a concentration of 15%: 15%, 15%: 20 %, 20%: 20%. This research used laboratory experimental methods. The results of the physical properties test showed that the resulting preparations gave a light purple to purplish pink color, had a distinctive odor of pafrum oleum rose, had a soft texture, all preparations had a homogeneous composition, the ph value of the preparations ranged from 6.00 – 6.45, the best polish at concentrations dye 20%: 20%, for 14 days of observation the color on all preparations did not change with light, and the most preferred preparations by researcher are those with dye concentrations of 20%: 20%. It shows that it can be concluded that a combination of ethanol extract of Purple Sweet Potato and Red Cana Flower. Can be used as a natural dye in blush preparations. Keywords:  Ipomoea batatas L., Canna coccinea Mill., Blusher. ABSTRAK  Ubi Jalar Ungu (Ipomoea batatas L.) dan Bunga Kana Merah (Canna coccinea Mill.) mengadung pewarna alami (antosianin) yang digunakan sebagai zat pewarna alami alternatif mapun sebagai antioksidan alami. Penelitian ini bertujuan untuk membuat serta mengetahui evaluasi fisik sediaan perona pipi dengan memanfaatkan pewarna alami pada kombinasi ekstrak Ubi Jalar Ungu dan Bunga Kana Merah dengan konsentrasi 15%:15%, 15%:20% dan 20%:20%. Penelitian ini menggunakan metode eksperimental laboratorium. Hasil pengujian sifat fisik menunjukan bahwa sediaan yang dihasilkan memberikan warna ungu muda hingga merah muda keunguan, bau khas parfum oleum rose, teksturnya lembut, semua sediaan memiliki susunan yang homogen, nilai pH sediaan berkisar 6,00 - 6,45, polesan terbaik pada konsentrasi zat warna 20%:20%, selama 14 hari pengamatan warna pada semua sediaan tidak mengalami perubahan terhadap cahaya, dan sediaan yang paling disukai oleh panelis adalah sediaan dengan konsentrasi zat warna 20%:20%. Dengan demikian dapat disimpulkan bahwa kombinasi ekstrak etanol Ubi Jalar Ungu dan Bungu Kana Merah dapat digunkan sebagai pewarna alami dalam sediaan perona pipi. Kata kunci: Ipomoea batatas L., Canna coccinea Mill., Perona pipi


2005 ◽  
Vol 48 (2) ◽  
pp. 187-193 ◽  
Author(s):  
Seyis Isil ◽  
Aksoz Nilufer

In this study, some physiological conditions affecting the activity of xylanase enzyme produced from Trichoderma harzianum 1073 D3 were determined. In addition, stabilization of pH and temperature in liquid and semi-solid state cultivation media were investigated. It was concluded that for maximum xylanase activity, incubation at 60°C in an enzyme incubation medium with pH 5 that contained 1 % xylan was appropriate. The stability studies showed that the enzyme was relatively stable in the pH range 3-7 and retained more than 50 % of its original activity after four months.


2013 ◽  
Vol 29 (2) ◽  
pp. 399-404
Author(s):  
V. Vukovic ◽  
M. Vicentijevic ◽  
N. Plavsa

In the stability test of the mastitis reagent ad us.vet., as the finished product, three production series were tested in quantities of 500 ml of the sample, under appropriate storage conditions. For the testing, the appropriate uniformity of temperature and relative humidity was provided. Also, the procedure of the stability test was determined, which included the initial state, then every three months until the end of the first trial and a final testing at the end of shelf life (0, 3, 6, 9, 12 and 18 months). Of the tested parameters the following were included: appearance, pH value of the solution, dry residue (in %) and microbiological purity.


2017 ◽  
Vol 14 (2) ◽  
pp. 63-68
Author(s):  
NINDYA NARESWARI ◽  
ANANG KUNCORO

Nareswari N, Kuncoro A. 2016. Preparation of essential oil ointment of lime leaves (Citrus amblycarpa) and stability test on base type used. Biofarmasi 14: 63-68. Citrus lime has a content of volatile oil contained in the leaves and the skin. Essential oils from the leaves of citrus lime-containing β-pinene, linalool, citronellal, and geraniol citronellol. The yield of essential oil of citrus lime leaves 0,47% could inhibit the growth of bacteria S.aureus with KBM and the MIC values of 0,039% (v / v).This research is design experimental that used Pre Test Post Test Control Desain. The essential oil for skin medication has to be made in practical and stable preparation. Ointment is a semi-solid preparation which is easy to be applied and to be used as the external medicine.The use of essential oil of citrus lime leaf was made in ointment preparation with three varieties of basis, those are water-soluble basis, absorptive bases and base hydrocarbon, in order for the ointment to be easily applied into skin. The physical stability test series which consisted of the homogeneity, the organoleptic, the viscosity the adhesiveness, and the dispersiveness and the acidity level (pH) of the ointment preparation was tested for 8 weeks in order to investigate the most stable ointment basis out of the three formulae to make the ointment of the essential oil of citrus lime (Citrus amblycarpa (Hassk) Ochse). Next, the stability of the ointment preparations was investigated from the data which contained the results of the observation from the first week to the eighth week. The data were analyzed statistically by using the Kolmogorov-Smirnov analysis technique. Finally, the data were analyzed by using the one-way Analysis of Variance (ANOVA) in order to investigate the effect of the difference in the basis of the ointment on the stability of the ointment preparations. The results of the research indicate that all three types of base oils used in ointment citrus lime leaves have a good physical stability test based on the results of the viscosity, the acidity level (pH), the dispersiveness and the adhesiveness.


2021 ◽  
Vol 3 (2) ◽  
pp. 151-160
Author(s):  
Widitia Pristifa Darajati ◽  
◽  
Yani Ambari ◽  

Cayenne pepper leaf (Capsicum frutescents L) is one of the natural ingredients that contains chemical compounds including saponins, alkaloids, terpenoids, quinones and flavonoids. Saponin and flavonoid compounds in cayenne pepper leaves have a role to stimulate hair growth. So that it can be used to overcome the problem of hair loss, where hair loss often occurs in the community dueto lack of nutritional intake and excessive use of chemicals. To overcome this, this research was carried out which aims to use preparations from natural ingredients of ethanol extract of cayenne pepper leaves which were made into hairtonic preparations with variations of propylene glycol and 96% ethanol Hairtonic formulations used 96% ethanol, menthol, propylene glycol, methyl paraben, propyl paraben, and aquades. Then a physical stability test was carried out to determine at what concentration the hairtonic preparation produced good physical stability. Hairtonic physical stability test was carried out for 14 days of storage with organoleptic results. Brownish orange color in the form of a clear solution and distinctive aroma of cayenne pepper leaf extract, the pH test was from the last cycle Formulation 1: 4.9 then Formulation 2: 5.0 and Formulation 3. : 5.1. Still in the skin pH range of 4.5-6.5, the Viscosity test is from the last cycle of Formulation 1: 1.01 Cps then Formulation 2: 0.95 Cps and Formulation 3: 1.06 Cps. Still in the hair tonic viscosity specification, which is below 5 Cps, in the Specific Gravity test in Formulation 1: 0.9950 gram/ml. then Formulation 2: 0.9951 gram/ml. and Formula 3: 0.9978 gram/ml. Still in the hair tonic viscosity specification, which is ±1 gram/ml. From these results, it can be seen that at concentrations of propylene glycol 10%, 15%, 20% and ethanol 5%, 10%, 15% produced good physical stability


2021 ◽  
Vol 1 ◽  
pp. 1059-1070
Author(s):  
Asri Septiani ◽  
W Wirasti ◽  
S Slamet ◽  
Urmatul Waznah

AbstractGreen tea is a plant that contains antioxidants. The content of green tea compounds that act as antioxidants are polyphenols. The addition of natural antioxidants in hydrogel masks has the potential as an alternative to synthetic antioxidants. The purpose of this study was to determine the antioxidant activity of the hydrogel mask preparation of green tea (Camellia sinensis L.) ethanol extract. The method of determining antioxidant activity was carried out by the -Carotene Bleaching (BCB) method. The stability test of the preparation using the cycling test method was carried out for 6 cycles including organoleptic, viscosity, pH, homogeneity tests. The data obtained from the antioxidant activity test is the IC50 value. The IC50 results of the green tea ethanol extract were 27,162 ppm, while the IC50 values for the formulations 1, 2 and 3 were 40,893 ppm, respectively; 35,348 ppm; and 32,270 ppm. The results of the stability test showed that the preparation was stable from the parameters of viscosity, pH and homogeneity but not stable from the organoleptic parameters because there was a color change in the preparation containing the extract after the cycling test process. In conclusion, both extracts and hydrogel mask preparations contain high antioxidants with relatively stable dosage forms.Keywords: Green Tea, Antioxidants, Hydrogel Mask, -Carotene Bleaching (BCB), IC50. AbstrakTeh hijau merupakan salah satu tanaman yang mengandung antioksidan. Kandungan senyawa teh hijau yang berperan sebagai antioksidan adalah polifenol. Penambahan antioksidan alami pada masker hidrogel berpotensi sebagai alternatif pengganti antioksidan sintetis. Tujuan penelitian ini adalah mengetahui aktivitas antioksidan sediaan masker hidrogel ekstrak etanol teh hijau (Camellia sinensis L.). Metode penentuan aktivitas antioksidan dilakukan dengan metode β-Carotene Bleaching (BCB). Pengujian stabilitas sediaan dengan metode cycling test dilakukan sebanyak 6 siklus meliputi uji organoleptik, viskositas, pH, homogenitas. Data yang diperoleh dari uji aktivitas antioksidan berupa nilai IC50. Hasil IC50 ekstrak etanol teh hijau sebesar 27,162 ppm, sedangkan pada sediaan menunjukan nilai IC50 berturut-turut dari formulasi 1, 2 dan 3 sebesar 40,893 ppm; 35,348 ppm; dan 32,270 ppm. Hasil uji stabilitas menunjukkan sediaan stabil dari parameter viskositas, pH dan homogenitas tetapi tidak stabil dari parameter organoleptik karena terjadi perubahan warna pada sediaan yang mengandung ekstrak setelah proses cycling test. Kesimpulannya ekstrak maupun sediaan masker hidrogel mengandung antioksidan tinggi dengan bentuk sediaan relatif stabil.Kata kunci:Teh Hijau; Antioksidan; Masker Hidrogel; β-Carotene Bleaching (BCB);IC50.


2019 ◽  
Vol 16 (01) ◽  
pp. 8
Author(s):  
Husnani Husnani ◽  
Fitri Sri Rizki

ABSTRACTDayak onion contains alkaloid compounds, flavonoids, saponins, tannins, glycosides, and triterpenoids which have anti-acne effects. This study aims to make cream formulas from Dayak onion ethanol extract and evaluate the physical quality characteristics of cream. The cream formulation from dayak onion extract was made with extract concentration of 100 mg/ml with stearic acid and triethanolamine as emulgator. Stearic acid and triethanolamine concentrations used were FI (6%: 2%), FII (12%: 3%), FIII ( 18%: 3%). The creams were evaluated for its physical quality characteristics, namely organoleptic, homogeneity, pH, dispersion, cream type and viscosity. From the evaluation of physical quality characteristics, it can be concluded that Formula III is the best formula that meets good cream quality requirements. The Dayak onion ethanol extract cream is an O/W type cream resulting in semi-solid, brown, organoleptic and dayak onion odor. In the homogeneity test there is no clumping on the cream preparation so that the preparation is homogeneous. The pH value is 6, so the cream is safe for the face. The spreadability of FIII is 7.52 cm, meets the requirements. The viscosity of F III is 32000 cPs, meets the requirements of a good cream preparation viscosity.Keywords: Formulation, Cream, Dayak Onion Extract (Eleutherine palmifolia (L.) Merr).


Processes ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 50
Author(s):  
Barbara D. Weiß ◽  
Michael Harasek

This review studies unwanted precipitation reactions, which can occur in SO2 absorption processes using a magnesium hydroxide slurry. Solubility data of potential salts in the MgO-CaO-SO2-H2O system are evaluated. The reviewed data can serve as a reliable basis for process modeling of this system used to support the optimization of the SO2 absorption process. This study includes the solubility data of MgSO3, MgSO4, Mg(OH)2, CaSO3, CaSO4, and Ca(OH)2 as potential salts. The solubility is strongly dependent on the state of the precipitated salts. Therefore, this review includes studies on the stability of different forms of the salts under different conditions. The solubility data in water over temperature serve as a base for modeling the precipitation in such system. Furthermore, influencing factors such as pH value, SO2 content and the co-existence of other salts are included and available data on such dependencies are reviewed. Literature data evaluated by the International Union of Pure and Applied Chemistry (IUPAC) are revisited and additional and newer studies are supplemented to obtain a solid base of accurate experimental values. For temperatures higher than 100 °C the available data are scarce. For a temperature range from 0 to 100 °C, the reviewed investigations and data provide a good base to evaluate and adapt process models for processes in order to map precipitations issues accurately.


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