scholarly journals A Study to Assess the Neurocognitive Profile of Patients with OCD and Depression

2020 ◽  
Vol 9 (4) ◽  
pp. 5-8
Author(s):  
Musuku Srikanth Reddy

Background: The present study was conducted to assess the neurocognitive profile of patients with OCD and depression. Subjects & Methods: It comprised of patients of OCD (42) and depression (42) of both genders. An equal number of healthy control was also recruited. VAIS and performance tests of intelligence (BSS) were recorded. Results: Group I had 22 males and 20 females, group II had 18 males and 24 females and group III had 21 males and 21 females. The value for VAIS and performance tests of intelligence (BSS) parameters such as information were 94.2, 96.4 and 98.3 in all groups respectively, digit span was 103.4, 102.5 and 105.6 in all groups respectively, arithmetic was 95.8, 96.2 and 8.4 in all groups respectively, comprehension was 102.4, 104.5 and 107.3 in all groups respectively, verbal quotient was 105.2 in group I, 103.6 in group II and 10.6.7 in group III respectively. Block design was 9.12, 10.2 and 10.4 in all groups respectively, pass along test was 9.4, 9.8 and 10.2 in all groups respectively and the performance quotient was 102.2, 103.5 and 10.5.7 in all groups respectively. The difference was non-significant (P> 0.05). Conclusion: Neuropsychological/cognitive parameters in patients with OCD, depression and healthy control were comparables.

1960 ◽  
Vol 11 (1) ◽  
pp. 75 ◽  
Author(s):  
M Wodzicka

The monthly wool growth of three groups of rams was studied at Beltsville, Maryland. Group I received natural daylight (at 38° 53' N.) and was shorn monthly. Group II had a 7:17 hours of daylight to hours of darkness rhythm and was shorn every 6 months, once in winter and once in summer. Group III received natural daylight and was likewise shorn every 6 months. The rams of all groups produced more wool in summer than in winter. This difference was significant (P<0.001). The mean body weight and food intake were both greater in the winter months, which indicated that the seasonal rhythm of wool growth was not a consequence of poorer feeding in winter. The rams which were shorn monthly (group I) grew considerably more wool than the other two groups, but the difference was not statistically significant. The short-day treatment of group II did not increase the annual wool production nor decrease the seasonal rhythm of wool growth. The balance of evidence from this and other experiments indicates that temperature rather than light controls the seasonal rhythm of wool growth.


2002 ◽  
Vol 20 (2-3) ◽  
pp. 56-65 ◽  
Author(s):  
Chin-Keng Sim ◽  
Pei-Chang Xu ◽  
Hwee-Leng Pua ◽  
Guojing Zhang ◽  
Tat-Leang Lee

Acupuncture has been shown to be effective in experimental and clinical acute pain settings. This study aims to evaluate the effect of preoperative electroacupuncture (EA) on intraoperative and postoperative analgesic (alfentanil and morphine) requirement in patients scheduled for gynaecologic lower abdominal surgery. Ninety patients were randomly assigned to one of three groups: Group I (control group) –received placebo EA for 45 minutes before induction of general anaesthesia (GA); Group II –preoperative EA instituted 45 minutes before induction of GA; Group III – 45 minutes of postoperative EA. The Bispectral Index monitor was used intraoperatively to monitor the hypnotic effect of anaesthetic drugs, and alfentanil was titrated to maintain the blood pressure and pulse rate within ±15% of basal values. Postoperative pain was managed by intravenous morphine via a patient-controlled analgesia (PCA) device. Patients in Group II (0.44 ± 0.15μg/kg/min) received less alfentanil than those in Group III (0.58 ± 0.22μg/kg/min) (p=0.024), but not significantly less than those in Group I (0.51 ± 0.21μg/kg/min) (p=0.472). Postoperative morphine consumption was numerically lower in Group II compared with the other groups; however, the difference was statistically significant only during the period of 6–12 hours between Group II [0.03 (0.05) mg/kg] and Group I [0.10 (0.11) mg/kg] (p=0.015), and Group II and Group III [0.08 (0.10) mg/kg] (p=0.010). The 24-hour cumulative morphine consumption for Group II (0.52 ± 0.19mg/kg) was less than that for either Group I (0.68 ± 0.38mg/kg) or Group III (0.58 ± 0.27mg/kg), but the difference did not reach significance. In conclusion, preoperative EA leads to a reduced intraoperative alfentanil consumption, though this effect may not be specific, and has a morphine sparing effect during the early postoperative period.


2002 ◽  
Vol 116 (11) ◽  
pp. 917-919 ◽  
Author(s):  
Khader J. Abdul-Baqi ◽  
Farouk M. N. Shakhatreh

This study was performed to find out the effectiveness of three different treatments of patients having acute tonsillopharyngitis. Three groups of patients were selected (50 patients in each group). Group I received one antibiotic according to the result of culture and sensitivity test, while groups II and III received two antibiotics or one antibiotic respectively without a culture and sensitivity test. Diagnosis was based on the acutely subjective symptoms of sore throat and positive clinical examination findings. The effectiveness of treatment in group I (96 per cent) was statistically significant (p<0.05) and higher than group II (82 per cent) and group III (74 per cent), while the difference between group II and III was not statistically significant (p>0.05).Our findings demonstrate that a culture and sensitivity test of the throat swab is necessary before treating acute tonsillopharyngitis. It was suggested that there should be appropriate selection of antibiotics to preserve normal flora, avoidance antibiotics for viral infections, patient compliance with prescription and educational programmes directed at patients and physicians. All of these measures would assist in reducing the volume of antibiotic use, bacterial resistance and the overall cost of treatment of tonsillopharyngitis.


2015 ◽  
Vol 03 (01) ◽  
pp. 039-046
Author(s):  
Geetanjali Bansal ◽  
Ajay Bansal ◽  
Bhupinder Padda

AbstractThe aim of this study was to evaluate and compare the sealing ability to obturate oval canals with three thermoplasticizedguttaperchaobturation techniques taking lateral condensation technique as the control. Ninety-five freshly extracted teeth were decoronated at 2mm coronal to CEJ. Biomechanical preparation was done using step back technique. The teeth were divided into three experimental groups of 30 teeth each and one control group of 5 teeth. The group I (control group) was obturated with lateral condensation technique, group II obturated with injectable thermoplasticizedguttapercha technique, group III obturated with thermoplasticizedguttapercha with downpack and backfill technique andgroup IV obturated with core carrier thermoplasticizedguttapercha technique. The sealability of each technique was assessed by a dye penetration method. The roots were given two full layers of nail polish varnish except apical 2mm. Specimens were then immersed in India ink for 48 hours. Robertson’s technique was used to clear the specimens. The linear dye penetration was measured from anatomic apex to the deepest extent of dye penetration in a coronal direction using triocular stereomicroscope at 10 × magnification. The mean dye leakage of group I was 2.6700mm;group II 0.1713mm;group III 3.3977mm; group IV 2.3210mm. When the means of all the four groups were compared using Kruskal Wallis test the difference was found to be very highly significant with the value<.001**, meaning there by that group II is significantly better than the other three groups as far as sealing ability is concerned.


1967 ◽  
Vol 10 (3) ◽  
pp. 219-228 ◽  
Author(s):  
R. J. Wood

Inheritance of DDT resistance has been studied in crosses between the highly resistant ‘T’ strain of A. aegypti (constituted by inbreeding from the TRINIDAD DDT-resistant stock) and the ‘64’ susceptible strain.Larval DDT resistance derives from a major gene RDDT1 on linkage group II, the order being RDDT1–s–y. Linkage group III may also contribute to larval resistance. Linkage group I makes no contribution.Adult DDT resistance derives from a major gene RDDT2, 18·2 ± 2·1 units from the market blt on linkage group III. Linkage group II has no influence on adult resistance.Selection with DDT to retain only RDDT1/+ segregants in larvae of backcrosses RDDT1/+×+/+ did not increase resistance in resulting adults, confirming the difference in genetic mechanism at the two stages.The F1 progenies from reciprocal crosses between ‘T’ and ‘64’ differed slightly but significantly in larval resistance, modifying the influence of the major gene RDDT1 in the heterozygote.The early developmental stages of the RDDT1/+ phenotype (up to the fourth larval stage) were more viable than the +/+ phenotype in backcross segregation. The difference in mortality probably exceeded 30%.


2020 ◽  
Vol 59 ◽  
pp. 17-25
Author(s):  
S. F. Antonenko

The scientific experiment was carried out in two stages at State enterprise pilot farm “Hontarivka”, Vovchansk district, Kharkiv region. First stage. In a retrospective analysis of the rearing calf intensity from 3 to 6 months revealed that the highest live weight at 6-month age had animals of group III, .which is probably 47.0 kg or 34.6% and 23.0 kg or 14.4% (P < 0.001 in both comparison cases) outperformed peers I and II groups. A similar trend was observed in the analysis of live weight of heifers at 9 and 12-month age. Live weight at insemination in the higher growth group also had better rates of 4.0 and 3.7%, respectively, in animals of groups I and II (P < 0.001–0.05). It should be noted that the required live weight for insemination at heifers at growth rates of up to 500 g was reached in only 20.3 months, however, in the other two groups, the insemination age decreased by 1.5 and 1.7 months. Firstcalf heifers from group III also had the highest milk expectancy of 170.0 and 123.0 kg, or 3.1 and 2.3%, respectively, then animals in groups I and II. In the age period from 6 to 9 months it was found that at 9-month age heifers of group III had a higher live weight against animals of I and II groups respectively by 39.0 and 16.0 kg or 18.8 and 7.0% (P < 0.001 in both comparison cases). Intergroup differences by this indicator at 12-month age hiefers decreased to 35.0 and 8.0 kg, respectively, or 13.0 and 2.7% (P < 0.001 in both cases of comparison), which provided an advantage for the live weight of group III over I and II groups during the first fruitful insemination. Whereas the age of first fruitfull insemination, on the contrary, was lower at heifers of group III at 49 and 34 days than at groups I and II heifers. The highest milk productivity was also found at firstcalf heifers of group III at 634 kg or 12.3% (P < 0.001) and at 137 kg or 2.5% against animal I and II groups. The heifer live weight at the period from 9 to 12 months corresponded to the established differences at other age periods generally. And 12-month age calves of group III also significantly exceeded the analogues of group I by 38.0 kg or 14.0% (P < 0.001) and peers of group II – by 23.0 kg or 8.0% (P < 0.001). The live weight at fruitfull insemination of group III heifers was the largest and the difference compared with animals of group I was 21.0 kg or 5.3% (P < 0.01) and group II – 19.0 kg or 4.8% (P < 0.001). Group III animals also had the highest milk productivity, which is likely to be higher than group I peers by 751 kg or 14.5% (P < 0.001) and group II animals by 552 kg or 10.3% (P < 0.001). Second stage. It was found that during the experiment, live weight of free-stall keeping heifers were outnumbered by peers. In particular, the live weight of group I animals at the first month of the experiment was less by 8.0 kg or 2.9%, the second by 15.0 kg or 4.7% (P < 0.05) and the third by 19.0 kg or 5.4% against peers of group II. A similar pattern was observed in the estimation of intensive growth of these animals. However, at the end of the experiment, the heifers of the experimental group were 7.0 cm or 5.9% (P < 0.001) higher in the withers, 7.0 cm or 5.6% (P < 0.001) in the back, and the sacrum – 6.0 cm or 4.7% (P < 0.001). They showed deeper breasts by 3.0 cm or 4.9% (P < 0.01), larger breast widths – by 2.0 cm or 5.4% (P < 0.01), width in macaques – by 2.0 cm or 4.9% (P < 0.01), oblique torso length – 8.0 cm or 5.8% (P < 0.001), chest circumference 9.0 cm or 5.6% (P < 0.001) and girth – 1.0 cm or 6.1% (P < 0.01). It should be noted that from the second month of the research the animal number the free-stall keeping animal number, which ready for insemination, was more at 2.3 times or 5 goals than stall keeping heifers, and their live weight was more at 8 kg or 3.0%. With age, the differences between the groups gradually increased and by the third month reached 8 goals or 2.6 times and 19.0 kg or 5.7%.


2021 ◽  
Vol 61 ◽  
pp. 186-191
Author(s):  
І. F. Chernev

Purpose of research: In the process of growth and development of pigs, to study the hematological and biochemical parameters of the blood of young pigs obtained by combining two breed sows with purebred and hybrid boars. Material and research methods. The studies were carried out at the State Agrarian University of Moldova and at the pork production enterprise "SC Agroseminvest SRL". To achieve the goal, the research material was two breed sows large white x Landrace (maternal form) and purebred and hybrid boars: I-pietrain; II-large white x landrace x pietrain; III-(large white x landrace x pietrain) x pietrain; IV-duroc; V-pietrain x duroc, (paternal form). In order to determine the influence of hybrid boars on the growth and development of the offspring, five experimental groups were formed according to the principle of analogs of 6 sows and 30 heads of young animals (15 pigs and 15 castrates). Research results .The data obtained indicate an insignificant increase in the hemoglobin content in group I in comparison with group V animals with a moderate significance of the difference, which was 4 g/l (B ≥ 0.95). Consequently, in groups where meat breeds Pietrain and Duroc were used in various combinations, the hemoglobin content was higher. The best results in terms of the content of erythrocytes were obtained in groups III and V, respectively 7.61 x 1012 и and 7.59 x 1012, and a significant difference was established between groups III and IV (B ≥ 0.99), while in the second group the content of erythrocytes was 0.39 lower than in group III (7.22 x 10¹²). Reliable data on the ALT content were obtained between young pigs of groups I and V (B ≥ 0.95). Some tendencies towards a higher content of AST in the second group have been established. The blood glucose level in hybrid young animals in different combination combinations ranged from 5.68 mmol/l (group I) to 6.19 (group II), and the calcium level from 2.55 mmol/l (group III) to 2.81 mmol/l (group II) with a moderate tendency to increase these indicators in group II. Conclusions: A higher hemoglobin content was found in the I group of animals in comparison with the V group with a moderate significance of the difference, which was 4 g/l (B ≥ 0.95). A significant difference was established between groups III and IV (B ≥ 0.99). A higher content of protein in the blood is found in groups I–II, and is more than 89 g/l. In hybrid young animals, the glucose level in different combination combinations ranged from 5.68 mmol/l (group I) to 6.19 (group II), and the calcium level from 2.55 mmol/l (group III) to 2.81 mmol/l (Group II) with a moderate tendency to an increase in these indicators in group II.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Artur Wdowiak

The aim of this study was to investigate the activity of myoinositol, in a court of 217 PCOS women undergoing intracytoplasmic sperm injection (ICSI), on pregnancy rate, embryo development, estradiol, and progesterone concentration in blood serum, superoxide dismutase (SOD), and catalase (CAT) in follicular fluid. Concerning the court of patient, 112 (groups I and II) out of 217 were PCOS women, whereas group III consisted of healthy subjects (not PCOS). Group I patients were treated with 400 μg of folic acid per day for 3 months before ICSI, whereas group II patients received 4000 mg of myoinositol and 400 μg of folic acid per day for 3 months before ICSI. Group II revealed a shorter embryo/blastocyst development period between microinjection and 5-cell stage compared to group I. The difference in SOD concentration between groups I and II and between groups II and III was statistically significant. In group II, 34.62% of pregnancies were obtained, whereas in group I this number reached 20% (NS). Myoinositol increased embryo development dynamics and accelerated blastocyst stage reaching time; however, no effect was shown on clinical pregnancy. Furthermore, it restored SOD concentration, lowered in PCOS women, but did not exert any effect on CAT concentration.


2015 ◽  
Vol 1 (2) ◽  
pp. 72
Author(s):  
Wahdah Norsiah

Examination of hemoglobin levels influenced leukocytosis sianmethemoglobin method that causes increased absorbance measurements of hemoglobin levels increased significantly and the false blood sample that has been diluted with a solution Drabkins in centrifugation at 3000 rpm for 10 minutes and then the absorbance of the supernatant was measured with a photometer at λ 546 nm. This study aimed to analyze the differences in hemoglobin level examination siamethemoglobin method with and without centrifugation at sample leukocytosis. This type of research is observational research laboratory. The study design was cross-sectional study. Samples were taken from the remaining blood samples of patients who have been examined leukositnya number more than 20,000 / uL with Hematology Analyzer (CEL-DYN Ruby) February-April 2014, and were divided into 4 groups based on criteria that group 1. leukocyte count of 20,000 / uL-29 999 / mL, group II. 30,000 / uL-39 999 / uL, the group III. 40,000 / uL-49,999 / uL, the group IV. More than 50,000 / uL. The number of samples taken were 20 samples of each group, a total sample of 80 samples. The analysis showed no significant difference in hemoglobin levels siamethemoglobin method with and without centrifugation at sample leukocytosis with a value of p = 0.000 less than 0.05 α. Leukocytosis Turbidity affects the difference in hemoglobin levels with and without centrifugation, the higher the number the greater the difference in leukocyte levels of hemoglobin, hemoglobin level examination results of the study based on the criteria of the number of leukocytes obtained by the difference in hemoglobin levels with and without centrifugation in group I. 0.22 ± 0.07 g / dL, group II 0.40 ± 0.22 g / dL, a group III. 0.44 ± 0.14 g / dL, Group IV. 0.85 ± 0.41 g / dL. The level of hemoglobin in the sample sianmethemoglobin method leukocytosis with more than 20,000 / uL need a centrifuge so that appropriate hemoglobin levels over the patient's clinical condition.


Author(s):  
I. I. Rosenfeld

Aim. The article discusses the results of a study using a patented method of two-layer laparoscopic repair of large and giant hiatal hernias using a biocarbon implant in comparison with other surgical techniques.Materials and methods. 716 patients were divided into 3 study groups based on the area of the size of the esophageal hernia defect: group I (314 patients) – with small (less than 5 cm2) and medium (5–10 cm2) hiatal hernias, that is, up to 10 cm2, which hernioplasty was performed only by the method of posterior cruraphy; group II (323 patients) – with large hernias 10–20 cm2: subgroup 1 (92 patients) underwent posterior cruraphy, subgroup 2 (231 patients) – alloplasty. Depending on the alloplasty technique, subgroup 2, in turn, was divided: subgroup A (89 people) – hernioplasty with a polypropylene implant and subgroup B (142 people) – hernioplasty with a medical biocarbon construction. Study group III (79 patients) – patients with giant diaphragmatic hernias of more than 20 cm2 using alloplasty: subgroup A (29 people) – hernioplasty with a polypropylene implant and subgroup B (50 patients) – alloplasty with a medical biocarbon construction.Results. When comparing group I with subgroup 1 of group II, the following results were obtained. Statistically significant differences were found in the degrees and types of diaphragmatic hernias. The average age of patients and statistical differences for it were insignificant. When comparing subgroup 1 with subgroup 2 of group II, statistically insignificant differences were found in the degrees and types of hiatal hernias. The difference in the average age of patients was also statistically insignificant. The difference in the average age of patients was also statistically insignificant. When comparing subgroup A with subgroup B of group II, statistically insignificant differences were found among themselves in the degrees and types of hiatal hernias. When comparing subgroup 2 of group II with group III, the difference turned out to be statistically significant in the distribution of patients by types and degrees of diaphragmatic hernias. When comparing subgroup A with subgroup B of group III by degrees and types of hiatal hernias, statistically insignificant differences were revealed.Conclusion. Posterior cruraphia in small and medium diaphragmatic hernias had significant statistical differences in types and degrees compared to that in large hernias, as well as in the average area of the hernial defect. Posterior cruraphia with hernioplasty in large hiatal hernias did not differ statistically significantly according to any of the criteria. Plastic surgery with a polypropylene implant with alloplasty of a biocarbon implant for large hernias did not differ significantly according to any of the criteria. Hernioplasty for large hiatal hernias, when compared with giant hernias, differed significantly only in the degree and type, as well as in the area of the hernial defect. «Onlay» plastic surgery with a polypropylene implant with alloplasty of biocarbon structures for giant hernias did not differ significantly according to any of the criteria, except for gender distribution, which did not have significant fundamental significance, which made it possible to make a more correct comparison of the results of surgical interventions in these research subgroups.


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