scholarly journals Literature Review : Pengaruh Batuk Efektif Untuk Pengeluaran Sputum Pada Pasien Tuberculosis

2021 ◽  
Vol 1 ◽  
pp. 1516-1523
Author(s):  
Ida Fauziyah ◽  
Nuniek Nizmah Fajriyah ◽  
Firman Faradisi
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Side Effects ◽  
Literature Review ◽  
The Body ◽  
Forced Expiration ◽  
Shortness Of Breath ◽  
Pharmacological Interventions ◽  
Tuberculosis Patients ◽  
Lung Expansion

AbstractTuberculosis (TB) is in infectious disease that attacks the lungs caused by the bacterium Mycobacterium tuberculosis. Tuberculosis patients usually have symptoms of a prolonged cough, from the cought it can cause shortness of breath in someone who experiences these symtoms because there are too many secretions that are difficult to expel, causing a forced expiration. Forced expiration is one of the non-pharmacological interventions carried out to expel secretions, increase lung expansion, mobilize secretions and prevent side effects of retention of secretions. The purpose of this study was to describe the effect of forced expiration for sputum extraction in tuberculosis patients. Used in this study was a literature review from a database that had been determined used the keywoard tuberculosis, forced expiration, and sputum extraction. Obtained after forced expiration was reduced in the number of secretions in the patient. This study is that forced expiration can effectively reduce the amount of secretions in the body of tuberculosis patients. Keywoard: Forced expiration; Sputum extraction; Tuberculosis (Pulponary tuberculosis) AbstrakTuberculosis (TB) adalah salah satu penyakit infeksi yang menyerang bagian paru-paru disebabkan oleh bakteri mycrobacterium tuberculosis. Pendertia tuberculosis biasanya memiliki gejala batuk yang berkepanjangan, dari batuk tersebut dapat menyebabkan sesak nafas pada seseorang yang mengalami gejala tersebut karena terlalu banyak sekret yang susah untuk dikeluarkan sehingga menyebabkan batuk efektif. Batuk efektif adalah salah satu tindakan non farmakologi yang dilakukan untuk pengeluaran sekresi, meningkatkan ekspansi paru, memobilisasi sekret dan mencegah efek samping dari retensi sekresi. Dari karya tulis ilmiah adalah untuk mengetahui gambaran tentang pengaruh batuk efektif untuk pengeluaran sputum pada pasien tuberculosis. Metode yang dilakukan dalam penelitian adalah literature review dari database yang telah ditentukan dengan menggunakan kata kunci Tuberculosis, latihan batuk efektif, dan pengeluaran sputum. Hasil yang didapatkan setelah dilakukan tindakan latihan batuk efektif yaitu banyaknya sekret pada pasien mulai berkurang. Kesimpulan karya tulis ilmiah ini bahwa tindakan latihan batuk efektif dapat mengurangi jumlah sekresi yang ada pada tubuh pasien tuberculosis.Kata kunci: Latihan batuk efektik; Pengeluaran Sputum; Tuberculosis ( TB Paru)

scholarly journals tuberculosis, efek samping, OTA KELUHAN PENDERITA TUBERCULOSIS TENTANG EFEK SAMPING OBAT ANTI TUBERCULOSIS DAN FAKTOR YANG MEMPENGARUHINYA DI UPTD KESEHATAN

2019 ◽  
Vol 3 (2) ◽  
pp. 85-93
Author(s):  
Agus Khoirul Anam
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Side Effects ◽  
Data Collection ◽  
Side Effect ◽  
Total Population ◽  
Health Workers ◽  
Tuberculosis Patients ◽  
Descriptive Research ◽  
Success Of Treatment

Abstract: Tuberculosis is an infectious disease caused by germs of a group of mycobacterium namely mycobacterium tuberculosis. The objective of the research is to identify Tuberculosis patients complaints in side effects of drug treatment anti-tuberculosis and factors that influences the success of treatment at the UPTD Health Blitar City. The design of the research is descriptive research. The samples of Research is all patients tuberculosis in UPTD Health Blitar City , a large sample as many as 40 people taken with the technique of total population. The data collection was carried out by giving the questionnaire. The time of data collection is performed on 28 March – 31 May 2016. Based on the research that has been carried out, the results obtained as much as 33.5% complainedmild side effects of OATS and 2.5% complained of severe side effects of OATS. In addition,to the factors influence the success of treatment that is obedience as much as 100.0%.  The recommendations in this research , it is expected that health workers can provide counseling routinely about the side effect of oats . Keywords:tuberculosis , side effects of treatment, oats

scholarly journals Gambaran pH urin pada pasien tuberkulosis paru dewasa di RSUP Prof. Dr. R. D. Kandou manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Satrio Z. Tuah ◽  
Arthur E. Mongan ◽  
Mayer F. Wowor
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Clinical Manifestations ◽  
The Body ◽  
Adult Patients ◽  
Acid Base Balance ◽  
Urine Ph ◽  
Probability Sampling ◽  
Tuberculosis Patients ◽  
Consecutive Sampling

Abstract: Tuberculosis (TB) is a chronic contagious infectious disease caused by Mycobacterium tuberculosis with several clinical manifestations and treatment with nephrotoxic drug regimen. This situation affects the kidney function to maintain acid-base balance of the body through urine excretion. This study aim to describe urine pH in adult tuberculosis patients in Prof. Dr. R. D. Kandou Hospital Manado. This was an observational descriptive study with samples taken by non-probability sampling, consecutive sampling types to get the urine of all tuberculosis adult patients with specified period and criteria. From 30 adult patients with pulmonary tuberculosis are inpatient and outpatient, showed the average pH of the urine in patients with pulmonary tuberculosis without comorbidities was 6.2 and in pulmonary tuberculosis patients with comorbidities was 6.4. Conclusion: The urine pH in adult pulmonary tuberculosis in RSUP. Prof. Dr. R. D. Kandou Manado with or without comorbidities are normal.Keywords: urine pH, urinalysis, tuberculosis. Abstrak: Tuberkulosis (TB) merupakan penyakit infeksi kronik menular yang disebabkan oleh Mycobacterium tuberculosis dengan beragam manifestasi klinis dan pengobatan yang menggunakan resimen obat nefrotoksik. Keadaan ini mempengaruhi ginjal dalam fungsinya untuk mempertahankan keseimbangan asam-basa tubuh melalui ekskresi urin. Penelitian ini bertujuan untuk mengetahui gambaran pH urin pada pasien tuberkulosis dewasa di RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ini adalah penelitian deskriptif observasional dan sampel diambil dengan cara non-probability sampling jenis consecutive sampling untuk mendapatkan urin dari semua pasien tuberkulosis dewasa dalam kurun waktu dan kriteria yang ditentukan. Dari 30 pasien tuberkulosis paru dewasa rawat inap dan rawat jalan, menunjukkan rerata pH urin pada pasien tuberkulosis paru tanpa penyakit penyerta adalah 6,2 dan pada pasien tuberkulosis paru dengan penyakit penyerta adalah 6,4. Simpulan: Gambaran pH urin pada penyakit tuberkulosis paru dewasa di RSUP Prof. Dr. R. D. Kandou Manado dengan atau tanpa penyakit penyerta adalah normal. Kata kunci: pH urin, urinalisis, tuberkulosis

scholarly journals LITERATUR REVIEW : PENERAPAN BATUK EFEKTIF DAN FISIOTERAPI DADA UNTUK MENGATASI KETIDAKEFEKTIFAN BERSIHAN JALAN NAFAS PADA KLIEN YANG MENGALAMI TUBERCULOSIS (TBC)

2020 ◽  
Vol 1 (2) ◽  
pp. 1-5
Author(s):  
Wahyu Widodo, Siska Diyah Pusporatri
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Literature Review ◽  
Respiratory Tract ◽  
Chest Physiotherapy ◽  
Google Scholar ◽  
Tuberculosis Patients ◽  
Airway Clearance ◽  
Keywords Chest

Tuberculosis is a disease caused by mycobacterium tuberculosis that get into respiratory tract and the lungs so that there was rash in alveoli or inflammation, the alveolar walls then will shrink. The prevalence of tuberculosis based on doctor diagnosis by provience 2013-2018 indonesia occupies 0,4% of the population. Purpose : The Purpose of writing literature review is to conduct research on clients who have tuberculosis with ineffective airway clearance. Method : The method research used by analyzing articles  and searching through google scholar by using the keywords “chest physiotherapy and effective cough”, “chest physiotherapy and effective cough”+”tuberculosis”, “management of effective cough and  chest physiotherapy” + “tuberculosis”, “effect of effective cough and chest physiotherapy” + “tuberculosis”. Results : The result from 5 journals found that there was a change in breathing rhythm, are able t secrete, shorthnes of breath decreases after effective coughing and chest physiotherapy. Conclusions : The conclutions application of effective cough and chest physiotherapy in tuberculosis patients who experience ineffective airway clearance can reduce shortness breath and spuntum and it is recommended that client can do effective chough and chest physiotherapy independently

scholarly journals Gambaran pemeriksaan makroskopis urin pada pasien tuberkulosis paru dewasa di RSUP Prof. Dr. R. D. Kandou Manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Vivin Mustikawangi ◽  
Glady I. Rambert ◽  
Mayer Wowor
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Side Effect ◽  
Research Method ◽  
Urine Specimen ◽  
Tuberculosis Patients ◽  
Almost All ◽  
Macroscopic Examination ◽  
Urine Colour

Abstract: Tuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis. Anti-tuberculosis drugs have nephrotoxic and hepatotoxic side effect. Renal and liver damage caused by the side effect of anti-tuberculosis drugs will make some changes in macroscopic urinalysis. Research Objective: To understand the description of macroscopic urinalysis on pulmonary tuberculosis patients in RSUP Prof. Dr. R. D. Kandou Manado. Research Method: Observational descriptive, to obtain the data of macroscopic urinalysis on pulmonary tuberculosis patients conducted in October - November 2016 at RSUP Prof. Dr. R. D. Kandou Manado.The research samples were random urine specimen and 24-hour urine specimen that meet with the predefined criteria. Result: Based on macroscopic urinalysis results on 30 patients, almost all of the colour, odour, clarity and volume examination results were normal. Only a couple of patients have macroscopic changes. Although in colour examination, rifampicin changes urine colour to orange. Conclusion: Based on the result, it can be concluded that macroscopic urinalysis on pulmonary tuberculosis patients either in-patient or out patient showed that there are no abnormalities in almost all of them.Keywords: pulmonary tuberculosis, urinalysis, macroscopic examination Abstrak: Tuberkulosis (TB) adalah penyakit akibat infeksi bakteri Mycobacterium Tuberculosis. Obat yang diberikan pada pasien TB bersifat nefrotoksik dan hepatotoksik. Kerusakan ginjal dan hati yang disebabkan oleh efek samping obat tersebut akan menunjukkan perubahan pada pemeriksaan makroskopis urin. Tujuan Penelitian: untuk mengetahui gambaran pemeriksaan makroskopis urin pada pasien tuberkulosis paru dewasa di RSUP Prof. Dr. R. D. Kandou Manado. Metode Penelitian: deskriptif observasional, untuk mendapatkan data tentang pemeriksaan makroskopis urin pada pasien tuberkulosis paru dewasa yang dilakukan sejak oktober-november 2016 di RSUP. Prof. Dr. R. D. Kandou Manado. Sampel penelitian adalah sampel urin sewaktu dan 24 jamdari semua pasien tuberkulosis paru yang memenuhi kriteria yang telah ditentukan. Hasil: Berdasarkan urinalisis pemeriksaan makroskopis pada 30 pasien, pemeriksaan warna, bau, kejernihan, dan volume sebagian besar normal. Hanya beberapa pasien yang mengalami perubahan makroskopis.Pada pemeriksaan warna, pemakaian rifampisin menyebabkan urin berwarna jingga. Simpulan: dari hasil penelitian dapat disimpulkan bahwa antara pemeriksaan makroskopis urin dengan pasien tuberkulosis paru dewasa baik yang dirawat inap maupun rawat jalan menunjukan hampir semua tidak ada kelainan. Kata kunci: tuberkulosis paru, urinalisis, pemeriksaan makroskopis

scholarly journals Synovial tuberculosis of the hand: An ancient disease in an unusual localisation

2017 ◽  
Vol 50 (02) ◽  
pp. 130-137 ◽  
Author(s):  
Renato Franz Matta Ramos ◽  
Lucas Cancian ◽  
Fernando Calcagnotto ◽  
Ricardo Zeni ◽  
Gabriel Varela ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Early Diagnosis ◽  
Literature Review ◽  
Case Reports ◽  
Transverse Carpal Ligament ◽  
Complete Excision ◽  
Antituberculosis Drugs ◽  
Osteoarticular Tuberculosis ◽  
The World

ABSTRACTBackground: Tuberculosis is the most prevalent infectious disease in the world. It is mainly caused by Mycobacterium tuberculosis. Osteoarticular tuberculosis represents 1%–3%. Tenosynovitis is the most common form of the disease in the hand. Aims: The aim of this study is to present an update of synovial tuberculosis. Materials and Methods: The authors present a literature review, the clinical and surgical management and case reports. Results: The outcomes were satisfactory and were not report complications. Conclusions: Early diagnosis, surgical transection of the transverse carpal ligament, debridement and complete excision of the infected synovium may be required, along with antituberculosis drugs. Knowledge of this disease in the hand can provide a better diagnosis and outcome.

scholarly journals Docking Molecular analysis of potential Drug Paritaprevir against Mycobacterium tuberculosis (Mtb)

2021 ◽  
Author(s):  
IVAN VITO FERRARI ◽  
PAOLO PATRIZIO
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Rna Polymerase ◽  
Binding Affinity ◽  
The Body ◽  
Oral Drug ◽  
Potential Drug ◽  
Autodock Vina ◽  
Ligand Efficiency ◽  
Candidate Drug

Background: Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, which kills 1.8 million annually. This is an infectious disease generally affects the lungs, but can also affect other parts of the body. Mtb RNA polymerase (RNAP) is the target of the first-line antituberculosis drug Rifampin (Rif). We report first time a Potential Drug Paritaprevir against with severe infectious disease , by in Silico approach, using Autodock Vina and Autodock 4 ( or MGL Tool), estimated with Pyrx and AMDock Software, calculating three different important parameters: Binding Affinity ( kcal/mol), estimated Ki ( in nM units) and Ligand Efficiency ( L.E. in kcal/mol). After a selective analysis of over 1000 drugs, processed with Pyrx (a Virtual Screening software for Computational Drug Discovery) in the Ligand Binding site pocket of the protein ( ID PDB 5UHB chain C,DNA-directed RNA polymerase subunit beta), we noticed high values of these 3 parameters mentioned above of Paritaprevir, concluding that it could be an excellent candidate drug for this type of infection. Indeed, from the results of Autodock Vina and Autodock 4 ( or Autodock 4.2 ), implemented with lamarckian genetic algorithm, LGA, trough AMDock Software, This oral drug, approved by FDA in 2014, both by Autodock Vina and Autodock Vina 4 has excellent Binding affinity value, ca. -10.00 kcal/mol, a Ki value 40 nM and Ligand efficiency ca -0.15 kcal/mol. These results are comparable to the drug crystallized in the above-mentioned protein, currently used against TBC.

scholarly journals Gambaran eritrosit urin pada pasien tuberkulosis paru dewasa di RSUP Prof. Dr. R. D. Kandou Manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Gracia S. Sinaga ◽  
Glady I. Rambert ◽  
Mayer F. Wowor
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Observational Research ◽  
Inclusion Criteria ◽  
High Power Field ◽  
Tuberculosis Patients ◽  
Duration Of Therapy ◽  
Normal Urine ◽  
Global Health Problem

Abstract: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Tuberculosis remains a major global health problem and ranks as the second leading cause of death from an infectious disease worldwide. Anti-tuberculosis drugs, such as streptomycin and rifampicin are nephrotoxic. If the kidney function decreased, especially the glomerulus there can be found blood cells in the urine. A small number of erythrocytes may be found in normal urine, about 0-2 cells per HPF (High Power Field). But more than three erythrocytes per HPF is generally considered hematuria. This study aims to describe about how the urine erythrocytes in adult pulmonary tuberculosis patients at RSUP Prof. Dr. R. D. Kandou Manado. Research design used is descriptive observational research. Samples were urine samples of all pulmonary tuberculosis patients that suit to inclusion criteria. This study was conducted from October to November 2016. The results of chemical urinalysis of urine erythrocytes are negative in 20 patients and positive in 10 patients, while the results of microscopic urinalysis of urine erythrocytes are normal in 26 patients and hematuria in 4 patients. Conclusion: Hematuria mostly found in males, age 56-65 years old, default tuberculosis type, the first category of anti-tuberculosis drugs, the duration of therapy about 3-4 months, and in patients with comorbid disease.Keywords: pulmonary tuberculosis, urinalysis, hematuria Abstrak: Tuberkulosis merupakan penyakit infeksi yang disebabkan oleh Mycobacterium tuberculosis. Tuberkulosis masih merupakan salah satu masalah kesehatan masyarakat di dunia dan menduduki peringkat kedua penyebab kematian oleh penyakit infeksi di dunia. Obat anti-tuberkulosis seperti streptomisin dan rifampisin memiliki efek nefrotoksik. Apabila fungsi ginjal terutama glomerulus telah rusak maka dapat ditemukan adanya eritrosit dalam urin. Pada urin normal terdapat eritrosit sekitar 0-2 sel/LPB. Jika ditemukan 3 sel/LPB atau lebih, maka disebut hematuria. Penelitian ini bertujuan untuk mengetahui gambaran eritrosit urin pada pasien tuberkulosis paru dewasa di RSUP Prof. Dr. R.D. Kandou Manado. Desain penelitian yang digunakan adalah deskriptif observasional. Sampel penelitian adalah sampel urin sewaktu dari semua pasien tuberkulosis paru yang memenuhi kriteria inklusi. Penelitian dilakukan sejak Oktober-November 2016. Dari hasil pemeriksaan eritrosit urin secara kimia didapatkan hasil negatif pada 20 pasien dan hasil positif pada 10 pasien, sedangkan pemeriksaan mikroskopis eritrosit urin ditemukan hasil normal pada 26 pasien dan hasil hematuria pada 4 pasien. Simpulan: Hematuria didapatkan lebih banyak pada pasien laki-laki, pada kelompok usia 56-65 tahun, pada jenis kasus putus obat, pada jenis pengobatan kategori 1, pada lama pengobatan 3-4 bulan, dan pada pasien dengan penyakit penyerta. Kata kunci: tuberkulosis paru, urinalisis, hematuria

scholarly journals Effectiveness Of Peppermint Aromatherapy To Minimize Shortness Of Breath In Patients With Pulmonary Tuberculosis

2021 ◽  
Vol 7 (3) ◽  
pp. 56-64
Author(s):  
Nunung Nurhayati ◽  
Eva Supriatin ◽  
Linlin Lindayani
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Respiratory Tract ◽  
Google Scholar ◽  
Shortness Of Breath ◽  
Pulmonary Tb

Tuberculosis is an infectious disease caused by the bacteria Mycobacterium tuberculosis with various symptoms. It spreads through droplets of people infected with TB bacilli. Patients with pulmonary TB have several different complaints that can exacerbate respiratory difficulties, including shortness of breath. Inhalation is a form of treatment by supplying steam ventilation directly to the respiratory tract. EBN is developed to assess the potency of aromatherapy peppermint to minimize shortness of breath in patients with pulmonary tuberculosis. This EBN uses literature-based approaches to analyze study findings collected from method article filter searches using Google Scholar and PubMed databases. Results revealed that the use of peppermint aromatherapy was successful against shortness of breath in patients with pulmonary tuberculosis.

The Potential of Natural Diterpenes Against Tuberculosis: An Updated Review

2020 ◽  
Vol 26 (24) ◽  
pp. 2909-2932 ◽  
Author(s):  
Kadidiatou O. Ndjoubi ◽  
Rajan Sharma ◽  
Ahmed A. Hussein
Keyword(s):  
Infectious Disease ◽  
Natural Products ◽  
Mycobacterium Tuberculosis ◽  
Side Effects ◽  
Medicinal Plants ◽  
Marine Species ◽  
Inhibitory Effects ◽  
Natural Sources ◽  
Antimicrobial Effects ◽  
Research Studies

Every year, 10 million people are affected by tuberculosis (TB). Despite being a preventable and curable disease, 1.5 million people die from TB each year, making it the world’s top infectious disease. Many of the frontline antibiotics cause painful and disagreeable side effects. To mitigate the side effects from the use of chemically synthesized or clinical anti-tubercular drugs, there are many research studies focussed on natural products as a source of potential anti-tuberculosis drugs. Among different phytoconstituents, several classes of diterpenoids exert significant antimicrobial effects. This review explores diterpenoids as potential anti-tubercular drugs from natural sources. A total of 204 diterpenoids isolated from medicinal plants and marine species are discussed that inhibit the growth of Mycobacterium tuberculosis. The literature from 1994-2018 is reviewed, and 158 diterpenoids from medicinal plants, as well as 40 diterpenoids from marines, are alluded to have antituberculosis properties. The antitubercular activities discussed in the review indicate that the type of diterpenoids, the Mtb strains, substituents attached to diterpenoids and their position in the diterpenoids general skeleton can change the compounds antimycobacterial inhibitory effects.

Side effects of using disinfectants to fight COVID-19

2020 ◽  
Vol 3 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Saeed Yari ◽  
Hanns Moshammer ◽  
Ayda Fallah Asadi ◽  
Alireza Mosavi jarrahi
Keyword(s):  
Infectious Disease ◽  
Electron Microscope ◽  
Side Effects ◽  
The Body ◽  
Toxic Effects ◽  
Specific Morphology ◽  
Hand Contact

Coronavirus refers to a group of widespread viruses. The name refers to the specific morphology of these viruses because their spikes look like a crown under an electron microscope. Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered crown-shaped virus. Human-to-human transmission of the coronavirus is through coughing, sneezing, discharge from the nose and mouth. The virus can be transmitted from 1 to 2 meters through coughing or sneezing. Another way of transmission is by hand contact with the environment and virus-infected surfaces. Various substances are used to disinfect the body and surfaces. However, improper and unsafe use of these disinfectants can lead to other toxic effects in people that can be far more dangerous than the virus itself.

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